Cohort description: The Danish Blood Donor Staphylococcus aureus Carriage Study

References

• Pedersen OB, Erikstrup C, Kotzé SR, et al. The Danish Blood Donor Study: a large, prospective cohort and biobank for medical research. Vox Sang. 2012;102(3):271. doi:10.1111/j.1423-0410.2011.01553.x21967299
   PubMed Web of Science ®Google Scholar
• Wertheim HF, Melles DC, Vos MC, et al. The role of nasal carriage in Staphylococcus aureus infections. Lancet Infect Dis. 2005;5(12):751–762. doi:10.1016/S1473-3099(05)70295-416310147
   PubMed Web of Science ®Google Scholar
• Kluytmans J, Van Belkum A, Verbrugh H. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks. Clin Microbiol Rev. 1997;10(3):505–520. doi:10.1128/CMR.10.3.5059227864
   PubMed Web of Science ®Google Scholar
• Hoefnagels-Schuermans A, Peetermans WE, Jorissen M, et al. Staphylococcus aureus adherence to nasal epithelial cells in a physiological in vitro model. Vitro Cell Dev Biol Anim. 1999;35(8):472–480. doi:10.1007/s11626-999-0054-0
   Web of Science ®Google Scholar
• Williams REO. Healthy carriage of Staphylococcus aureus: its prevalence and importance. Bacteriol Rev. 1963;27(1):56–71.14000926
   PubMedGoogle Scholar
• Cole AM, Tahk S, Oren A, et al. Determinants of Staphylococcus aureus nasal carriage. Clin Diagn Lab Immunol. 2001;8(6):1064–1069. doi:10.1128/CDLI.8.6.1064-1069.200111687441
   PubMedGoogle Scholar
• Nilsson P, Ripa T. Staphylococcus aureus throat colonization is more frequent than colonization in the anterior nares. J Clin Microbiol. 2006;44(9):3334–3339. doi:10.1128/JCM.00880-0616954269
   PubMed Web of Science ®Google Scholar
• Mertz D, Frei R, Periat N, et al. Exclusive Staphylococcus aureus throat carriage: at-risk populations. Arch Intern Med. 2009;169(2):172. doi:10.1001/archinternmed.2008.53619171814
   PubMedGoogle Scholar
• Mertz D, Frei R, Jaussi B, et al. Throat swabs are necessary to reliably detect carriers of Staphylococcus aureus. Clin Infect Dis. 2007;45(4):475–477. doi:10.1086/52001617638197
   PubMed Web of Science ®Google Scholar
• Wassenberg M, Kluytmans J, Erdkamp S, et al. Costs and benefits of rapid screening of methicillin-resistant Staphylococcus aureus carriage in intensive care units: a prospective multicenter study. Crit Care. 2012;16(1):R22. doi:10.1186/cc1118422314204
   PubMed Web of Science ®Google Scholar
• Blanc DS, Basset P, Nahimana-Tessemo I, Jaton K, Greub G, Zanetti G. High proportion of wrongly identified methicillin-resistant Staphylococcus aureus carriers by use of a rapid commercial PCR assay due to presence of Staphylococcal cassette chromosome element lacking the mecA gene. J Clin Microbiol. 2011;49(2):722–724. doi:10.1128/JCM.01988-1021159945
   PubMed Web of Science ®Google Scholar
• Aydiner A, Lüsebrink J, Schildgen V, et al. Comparison of two commercial PCR methods for methicillin-resistant Staphylococcus aureus (MRSA) screening in a tertiary care hospital. PLoS One. 2012;7(9):e43935. doi:10.1371/journal.pone.004393523028480
   PubMed Web of Science ®Google Scholar
• Mandell GL. Principles and Practice of Infectious Disease. 7th ed. Churchill Livingstone; Elsevier. 2009. ISBN 9781437720600.
   Google Scholar
• Wisplinghoff H, Bischoff T, Tallent SM, Seifert H, Wenzel RP, Edmond MB. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective Nationwide Surveillance Study. Clin Infect Dis. 2004;39(3):309–317. doi:10.1086/42194615306996
   PubMed Web of Science ®Google Scholar
• Benfield T, Espersen F, Frimodt-Møller N, et al. Increasing incidence but decreasing in-hospital mortality of adult Staphylococcus aureus bacteraemia between 1981 and 2000. Clin Microbiol Infect. 2007;13(3):257–263. doi:10.1111/j.1469-0691.2006.01589.x17391379
   PubMed Web of Science ®Google Scholar
• DANMAP. DANMAP 2017 - Use of Antimicrobial Agents and Occurrence of Antimicrobial Resistance in Bacteria from Food Animals, Food and Humans in Denmark. Available from: https://www.danmap.org/-/media/arkiv/projekt-sites/danmap/danmap-reports/danmap-2017/danmap2017.pdf?la=en. Accessed September 11, 2019. ISSN 1600-2032.
   Google Scholar
• Wertheim HF, Vos MC, Ott A, et al. Risk and outcome of nosocomial Staphylococcus aureus bacteraemia in nasal carriers versus non-carriers. Lancet. 2014;364:703–705. doi:10.1016/S0140-6736(04)16897-9
   Web of Science ®Google Scholar
• Kluytmans JAJW, Mouton JW, Ijzerman EPF, et al. Nasal carriage of Staphylococcus aureus as a major risk factor for wound infections after cardiac surgery. J Infect Dis. 1995;171(1):216–219. doi:10.1093/infdis/171.1.2167798667
   PubMed Web of Science ®Google Scholar
• White A. Increased infection rates in heavy nasal carriers of coagulase-positive staphylococci. Antimicrob Agents Chemother. 1963;161:667–670.14274980
   PubMedGoogle Scholar
• Kalmeijer MD, van Nieuwland-Bollen E, Bogaers-Hofman D, de Baere GA. Nasal carriage of Staphylococcus aureus is a major risk factor for surgical-site infections in orthopedic surgery. Infect Control Hosp Epidemiol. 2000;21(5):319–323. doi:10.1086/50176310823564
   PubMed Web of Science ®Google Scholar
• von Eiff C, Becker K, Machka K, Stammer H, Peters G. Nasal carriage as a source of Staphylococcus aureus bacteremia. N Engl J Med. 2001;344(1):11–16. doi:10.1056/NEJM20010104344010211136954
   PubMed Web of Science ®Google Scholar
• Lyytikäinen O, Ruotsalainen E, Järvinen A, Valtonen V, Ruutu P. Trends and outcome of nosocomial and community-acquired bloodstream infections due to Staphylococcus aureus in Finland, 1995–2001. Eur J Clin Microbiol Infect Dis. 2005;24(6):399–404. doi:10.1007/s10096-005-1345-315931453
   PubMed Web of Science ®Google Scholar
• Laupland KB, Ross T, Gregson DB. Staphylococcus aureus bloodstream infections: risk factors, outcomes, and the influence of methicillin resistance in Calgary, Canada, 2000–2006. J Infect Dis. 2008;198(3):336–343. doi:10.1086/58971718522502
   PubMed Web of Science ®Google Scholar
• Goerke C, Wolz C. Regulatory and genomic plasticity of Staphylococcus aureus during persistent colonization and infection. Int J Med Microbiol. 2004;294(2):195–202. doi:10.1016/j.ijmm.2004.06.01315493830
   PubMed Web of Science ®Google Scholar
• van Rijen MML, Bonten M, Wenzel RP, Kluytmans JAJW. Intranasal mupirocin for reduction of Staphylococcus aureus infections in surgical patients with nasal carriage: a systematic review. J Antimicrob Chemother. 2008;61(2):254–261. doi:10.1093/jac/dkm48018174201
   PubMed Web of Science ®Google Scholar
• van Rijen M, Bonten M, Wenzel R, Kluytmans J. Mupirocin ointment for preventing Staphylococcus aureus infections in nasal carriers. Cochrane Database Syst Rev. 2008;(4):CD006216. doi:10.1002/14651858.CD006216.pub218843708
   PubMed Web of Science ®Google Scholar
• Olsen K, Danielsen K, Wilsgaard T, et al. Obesity and Staphylococcus aureus nasal colonization among women and men in a general population. Wertheim HFL, ed. PLoS One. 2013;8(5):e63716. doi:10.1371/journal.pone.006371623667661
   PubMed Web of Science ®Google Scholar
• Olsen K, Sangvik M, Simonsen GS, et al. Prevalence and population structure of Staphylococcus aureus nasal carriage in healthcare workers in a general population. The Tromsø Staph and Skin Study. Epidemiol Infect. 2013;141(1):143–152. doi:10.1017/S095026881200046522440487
   PubMed Web of Science ®Google Scholar
• Holtfreter S, Grumann D, Balau V, et al. Molecular epidemiology of Staphylococcus aureus in the general population in Northeast Germany: results of the Study of Health in Pomerania (SHIP-TREND-0). J Clin Microbiol. 2016;54(11):2774–2785. doi:10.1128/JCM.00312-1627605711
   PubMed Web of Science ®Google Scholar
• Lebon A, Labout JAM, Verbrugh HA, et al. Dynamics and determinants of Staphylococcus aureus carriage in infancy: the Generation R Study. J Clin Microbiol. 2008;46(10):3517–3521. doi:10.1128/JCM.00641-0818667593
   PubMed Web of Science ®Google Scholar
• Rigas AS, Sørensen CJ, Pedersen OB, et al. Predictors of iron levels in 14,737 Danish blood donors: results from the Danish Blood Donor Study. Transfusion (Paris). 2014;54(3 Pt 2):789–796. doi:10.1111/trf.12518
   Web of Science ®Google Scholar
• Kaspersen KA, Dinh KM, Mikkelsen S, et al. Oral iron supplementation is not associated with short-term risk of infections: results from the Danish Blood Donor Study: ORAL IRON SUPPLEMENTATION AND INFECTIONS. Transfusion (Paris). 2019;59:2030–2038. doi:10.1111/trf.15221
   Web of Science ®Google Scholar
• Dinh KM, Pedersen OB, Petersen MS, et al. The impact of CCR5-Δ32 deletion on C-reactive protein levels and cardiovascular disease: results from the Danish Blood Donor Study. Atherosclerosis. 2015;242(1):222–225. doi:10.1016/j.atherosclerosis.2015.07.03126222902
   PubMed Web of Science ®Google Scholar
• Burgdorf KS, Felsted N, Mikkelsen S, et al. Digital questionnaire platform in the Danish Blood Donor Study. Comput Methods Programs Biomed. 2016;135:101–104. doi:10.1016/j.cmpb.2016.07.02327586483
   PubMed Web of Science ®Google Scholar
• Theut Riis P, Pedersen OB, Sigsgaard V, et al. Prevalence of patients with self-reported hidradenitis suppurativa in a cohort of Danish blood donors: a cross-sectional study. Br J Dermatol. 2018. doi:10.1111/bjd.16998
   Web of Science ®Google Scholar
• Didriksen M, Rigas AS, Allen RP, et al. Prevalence of restless legs syndrome and associated factors in an otherwise healthy population: results from the Danish Blood Donor Study. Sleep Med. 2017;36:55–61. doi:10.1016/j.sleep.2017.04.01428735922
   PubMed Web of Science ®Google Scholar
• Hansen TF, Hoeffding LK, Kogelman L, et al. Comorbidity of migraine with ADHD in adults. BMC Neurol. 2018;18(1). doi:10.1186/s12883-018-1149-6
   Web of Science ®Google Scholar
• Dinh KM, Kaspersen KA, Mikkelsen S, et al. Low-grade inflammation is negatively associated with physical Health-Related Quality of Life in healthy individuals: results from The Danish Blood Donor Study (DBDS). Tauler P, ed. PLoS One. 2019;14(3):e0214468. doi:10.1371/journal.pone.021446830921429
   PubMed Web of Science ®Google Scholar
• Jenkinson C, Layte R, Jenkinson D, et al. A shorter form health survey: can the SF-12 replicate results from the SF-36 in longitudinal studies? J Public Health. 1997;19(2):179–186. doi:10.1093/oxfordjournals.pubmed.a024606
   Web of Science ®Google Scholar
• Gandek B, Ware JE, Aaronson NK, et al. Cross-validation of item selection and scoring for the SF-12 Health Survey in nine countries: results from the IQOLA Project. J Clin Epidemiol. 1998;51(11):1171–1178. doi:10.1016/S0895-4356(98)00109-79817135
   PubMed Web of Science ®Google Scholar
• Perneger TV, Burnand B. A simple imputation algorithm reduced missing data in SF-12 health surveys. J Clin Epidemiol. 2005;58(2):142–149. doi:10.1016/j.jclinepi.2004.06.00515680747
   PubMed Web of Science ®Google Scholar
• Kaspersen KA, Pedersen OB, Petersen MS, et al. Obesity and risk of infection: results from the Danish Blood Donor Study. Epidemiology. 2015;26(4):580–589. doi:10.1097/EDE.000000000000030125978794
   PubMed Web of Science ®Google Scholar
• Lee J, Nordestgaard BG, Dahl M. Elevated ACE activity is not associated with asthma, COPD, and COPD co-morbidity. Respir Med. 2009;103(9):1286–1292. doi:10.1016/j.rmed.2009.04.00319423314
   PubMed Web of Science ®Google Scholar
• Hansen TF, Banasik K, Erikstrup C, et al. DBDS Genomic Cohort, a prospective and comprehensive resource for integrative and temporal analysis of genetic, environmental and lifestyle factors affecting health of blood donors. BMJ Open 2019;9(6):e028401. doi:10.1136/bmjopen-2018-028401.
   Google Scholar
• Landspatientregisteret (LPR) - Sundhedsdatastyrelsen. Available from: http://sundhedsdatastyrelsen.dk/da/registre-og-services/om-de-nationale-sundhedsregistre/sygedomme-laegemidler-og-behandlinger/landspatientregisteret.
   Google Scholar
• Lynge E, Sandegaard JL, Rebolj M. The Danish national patient register. Scand J Public Health. 2011;39(7 Suppl):30–33. doi:10.1177/140349481140148221775347
   PubMed Web of Science ®Google Scholar
• Mernelius S, Löfgren S, Lindgren P-E, Matussek A. The role of broth enrichment in Staphylococcus aureus cultivation and transmission from the throat to newborn infants: results from the Swedish hygiene intervention and transmission of S. aureus study. Eur J Clin Microbiol Infect Dis. 2013;32(12):1593–1598. doi:10.1007/s10096-013-1917-623818164
   PubMed Web of Science ®Google Scholar
• Sollid JUE, Furberg AS, Hanssen AM, Johannessen M. Staphylococcus aureus: determinants of human carriage. Infect Genet Evol. 2014;21:531–541. doi:10.1016/j.meegid.2013.03.02023619097
   PubMed Web of Science ®Google Scholar
• Andersen PS, Pedersen JK, Fode P, et al. Influence of host genetics and environment on nasal carriage of Staphylococcus aureus in Danish Middle-Aged and Elderly Twins. J Infect Dis. 2012;206(8):1178–1184. doi:10.1093/infdis/jis49122872733
   PubMed Web of Science ®Google Scholar
• Olsen K, Falch BM, Danielsen K, et al. Staphylococcus aureus nasal carriage is associated with serum 25-hydroxyvitamin D levels, gender and smoking status. The Tromsø Staph and Skin Study. Eur J Clin Microbiol Infect Dis. 2012;31(4):465–473. doi:10.1007/s10096-011-1331-x21811869
   PubMed Web of Science ®Google Scholar
• Eriksen NH, Espersen F, Rosdahl VT, Jensen K. Carriage of Staphylococcus aureus among 104 healthy persons during a 19-month period. Epidemiol Infect. 1995;115(1):51–60. doi:10.1017/s09502688000581187641838
   PubMed Web of Science ®Google Scholar
• Melles DC, Pauw E, van Den Boogaard L, et al. Host–microbe interplay in persistent Staphylococcus aureus nasal carriage in HIV patients. Microbes Infect. 2008;10(2):151–158. doi:10.1016/j.micinf.2007.10.01718248760
   PubMed Web of Science ®Google Scholar
• Nouwen JL, Ott A, Kluytmans-Vandenbergh MF, et al. Predicting the Staphylococcus aureus nasal carrier state: derivation and validation of a “culture rule.” Clin Infect Dis. 2004;39(6):806–811. doi:10.1086/42337615472812
   PubMed Web of Science ®Google Scholar
• van Belkum A, Verkaik NJ, de Vogel CP, et al. Reclassification of Staphylococcus aureus nasal carriage types. J Infect Dis. 2009;199(12):1820–1826. doi:10.1086/59911919419332
   PubMed Web of Science ®Google Scholar
• Liu CM, Price LB, Hungate BA, et al. Staphylococcus aureus and the ecology of the nasal microbiome. Sci Adv. 2015;1(5):e1400216. doi:10.1126/sciadv.140021626601194
   PubMed Web of Science ®Google Scholar
• Pennell LM, Galligan CL, Fish EN. Sex affects immunity. J Autoimmun. 2012;38(2–3):J282–J291. doi:10.1016/j.jaut.2011.11.01322225601
   PubMed Web of Science ®Google Scholar
• Burgdorf KS, Simonsen J, Sundby A, et al. Socio-demographic characteristics of Danish blood donors. PLoS One. 2017;12(2):e0169112. doi:10.1371/journal.pone.016911228182624
   PubMed Web of Science ®Google Scholar