Unintended target effect of anti-BCL-2 DNAi

Abdul Shukkur Ebrahim1 Lymphoma Research Laboratory

Mustapha Kandouz2 Department of Pathology, School of Medicine

Nada Emara1 Lymphoma Research Laboratory

Amara B Sugalski3 Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, USA

Leonard Lipovich3 Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, USA

Ayad M Al-Katib1 Lymphoma Research LaboratoryCorrespondence[email protected]

Pages 427-432 | Published online: 22 Sep 2017

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SiegelRLMillerKDJemalACancer statisticsCA Cancer J Clin201666173026742998
PubMed Web of Science ®Google Scholar
MohammadRMWangSAboukameelAPreclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-X(L) [(−)-gossypol] against diffuse large cell lymphomaMol Cancer Ther200541132115657349
PubMed Web of Science ®Google Scholar
MohammadRMGoustinASAboukameelAPreclinical studies of TW-37, a new nonpeptidic small-molecule inhibitor of Bcl-2, in diffuse large cell lymphoma xenograft model reveal drug action on both Bcl-2 and Mcl-1Clin Cancer Res20071372226223517404107
PubMed Web of Science ®Google Scholar
ArnoldAAAboukameelAChenJPreclinical studies of Apogossypolone: a new nonpeptidic pan small-molecule inhibitor of Bcl-2, Bcl-XL and Mcl-1 proteins in follicular small cleaved cell lymphoma modelMol Cancer200872018275607
PubMed Web of Science ®Google Scholar
Al-KatibAMSunYGoustinASSMI of Bcl-2 TW-37 is active across a spectrum of B-cell tumors irrespective of their proliferative and differentiation statusJ Hematol Oncol20092819220884
PubMed Web of Science ®Google Scholar
SmithMRAbubakrYMohammadRAntisense oligodeoxyribonucleotide down-regulation of bcl-2 gene expression inhibits growth of the low-grade non-Hodgkin’s lymphoma cell line WSU-FSCCLCancer Gene Ther1995232072128528964
PubMed Web of Science ®Google Scholar
MohammadRAbubakrYDanMBcl-2 antisense oligonucleotides are effective against systemic but not central nervous system disease in severe combined immunodeficient mice bearing human t(14;18) follicular lymphomaClin Cancer Res2002841277128311948143
PubMed Web of Science ®Google Scholar
RodriguezaWVWoolliscroftMJEbrahimASDevelopment and antitumor activity of a BCL-2 targeted single-stranded DNA oligonucleotideCancer Chemother Pharmacol201474115116624832107
PubMed Web of Science ®Google Scholar
EbrahimASKandouzMLiddaneAPNT2258, a novel deoxyribonucleic acid inhibitor, induces cell cycle arrest and apoptosis via a distinct mechanism of action: a new class of drug for non-Hodgkin’s lymphomaOncotarget2016727423744238427283896
PubMedGoogle Scholar
TolcherAWRodriguezaWVRascoDWA phase 1 study of the BCL2-targeted deoxyribonucleic acid inhibitor (DNAi) PNT2258 in patients with advanced solid tumorsCancer Chemother Pharmacol201473236337124297683
PubMed Web of Science ®Google Scholar
MohammadRMMohamedANSmithMRJawadiNSal-KatibAA unique EBV-negative low-grade lymphoma line (WSU-FSCCL) exhibiting both t(14;18) and t(8;11)Cancer Genet Cytogenet199370162678221615
PubMedGoogle Scholar
Al-KatibAMSmithMRKamandaWSBryostatin 1 downregulates mdr1 and potentiates vincristine cytotoxicity in diffuse large cell lymphoma xenograftsClin Cancer Res199845130513149607591
PubMed Web of Science ®Google Scholar
al-KatibAMohammadRHamdanMMohamedANDanMSmithMRPropagation of Waldenstrom’s macroglobulinemia cells in vitro and in severe combined immune deficient mice: utility as a preclinical drug screening modelBlood19938111303430428499639
PubMed Web of Science ®Google Scholar
Al-KatibAMAboukameelAMohammadRBisseryMCZuany-AmorimCSuperior antitumor activity of SAR3419 to rituximab in xenograft models for non-Hodgkin’s lymphomaClin Cancer Res200915124038404519509168
PubMed Web of Science ®Google Scholar
AltschulSFMaddenTLSchäfferAAGapped BLAST and PSI-BLAST: a new generation of protein database search programsNucleic Acids Res19972517338934029254694
PubMed Web of Science ®Google Scholar
AltschulSFGishWMillerWMyersEWLipmanDJBasic local alignment search toolJ Mol Biol199021534034102231712
PubMed Web of Science ®Google Scholar
EbrahimASSabbaghHLiddaneARaufiAKandouzMAl-KatibAHematologic malignancies: newer strategies to counter the BCL-2 proteinJ Cancer Res Clin Oncol201614292013202227043233
PubMed Web of Science ®Google Scholar
MoldoveanuTFollisAVKriwackiRWGreenDRMany players in BCL-2 family affairsTrends Biochem Sci201439310111124503222
PubMed Web of Science ®Google Scholar
MorcianoGGiorgiCBalestraDMcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell deathMol Biol Cell2016271203426538029
PubMed Web of Science ®Google Scholar
O’LearyBFinnRSTurnerNCTreating cancer with selective CDK4/6 inhibitorsNat Rev Clin Oncol201613741743027030077
PubMed Web of Science ®Google Scholar
FinnRSAleshinASlamonDJTargeting the cyclin-dependent kinases (CDK) 4/6 in estrogen receptor-positive breast cancersBreast Cancer Res20161811726857361
PubMed Web of Science ®Google Scholar
HamiltonEInfanteJRTargeting CDK4/6 in patients with cancerCancer Treat Rev20164512913827017286
PubMed Web of Science ®Google Scholar
SamaniAAYakarSLeRoithDBrodtPThe role of the IGF system in cancer growth and metastasis: overview and recent insightsEndocr Rev2007281204716931767
PubMed Web of Science ®Google Scholar
O’DonnellKAYuDZellerKIActivation of transferrin receptor 1 by c-Myc enhances cellular proliferation and tumorigenesisMol Cell Biol20062662373238616508012
PubMed Web of Science ®Google Scholar

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