Dichloroacetate enhances the antitumor efficacy of chemotherapeutic agents via inhibiting autophagy in non-small-cell lung cancer

References

• MaherARMiake-LyeIMBeroesJMShekellePGTreatment of Metastatic Non-Small Cell Lung Cancer: A Systematic Review of Comparative Effectiveness and Cost-EffectivenessWashington (DC)Department of Veterans Affairs (US)2012
   Google Scholar
• SpiroSGPorterJCLung cancer – where are we today? Current advances in staging and nonsurgical treatmentAm J Respir Crit Care Med20021661166119612403687
   PubMed Web of Science ®Google Scholar
• SongWTangZLiMPolypeptide-based combination of paclitaxel and cisplatin for enhanced chemotherapy efficacy and reduced side-effectsActa Biomater2014101392140224316362
   PubMed Web of Science ®Google Scholar
• WardPSThompsonCBMetabolic reprogramming: a cancer hallmark even Warburg did not anticipateCancer Cell20122129730822439925
   PubMed Web of Science ®Google Scholar
• PathakRKMarracheSHarnDADharSMito-DCA: a mitochondria targeted molecular scaffold for efficacious delivery of metabolic modulator dichloroacetateACS Chem Biol201491178118724617941
   PubMed Web of Science ®Google Scholar
• KimuraTTakabatakeYTakahashiAIsakaYChloroquine in cancer therapy: a double-edged sword of autophagyCancer Res2013733723288916
   PubMed Web of Science ®Google Scholar
• LevineBKroemerGAutophagy in the pathogenesis of diseaseCell2008132274218191218
   PubMed Web of Science ®Google Scholar
• GomesLRVessoniATMenckCFMicroenvironment and autophagy cross-talk: Implications in cancer therapyPharmacol Res201610730030727037157
   PubMed Web of Science ®Google Scholar
• SuZYangZXuYChenYYuQApoptosis, autophagy, necroptosis, and cancer metastasisMol Cancer2015144825743109
   PubMed Web of Science ®Google Scholar
• KorenIKimchiACell biology. Promoting tumorigenesis by suppressing autophagyScience201233888989023161981
   PubMed Web of Science ®Google Scholar
• RosenfeldtMTRyanKMThe role of autophagy in tumour development and cancer therapyExpert Rev Mol Med200911e3619951459
   PubMed Web of Science ®Google Scholar
• RubinszteinDCCodognoPLevineBAutophagy modulation as a potential therapeutic target for diverse diseasesNat Rev Drug Discov20121170973022935804
   PubMed Web of Science ®Google Scholar
• EggerMEHuangJSYinWMcMastersKMMcNallyLRInhibition of autophagy with chloroquine is effective in melanomaJ Surg Res201318427428123706562
   PubMed Web of Science ®Google Scholar
• RangwalaRChangYCHuJCombined MTOR and autophagy inhibition: phase I trial of hydroxychloroquine and temsirolimus in patients with advanced solid tumors and melanomaAutophagy2014101391140224991838
   PubMed Web of Science ®Google Scholar
• VoglDTStadtmauerEATanKSCombined autophagy and proteasome inhibition: a phase 1 trial of hydroxychloroquine and bortezomib in patients with relapsed/refractory myelomaAutophagy2014101380139024991834
   PubMed Web of Science ®Google Scholar
• BonnetSArcherSLAllalunis-TurnerJA mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growthCancer Cell200711375117222789
   PubMed Web of Science ®Google Scholar
• ChristofkHRVanderHMHarrisMHThe M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growthNature200845223023318337823
   PubMed Web of Science ®Google Scholar
• TanJJiangXYinGAnacardic acid induces cell apoptosis of prostatic cancer through autophagy by ER stress/DAPK3/Akt signaling pathwayOncol Rep20173831373138228731173
   PubMed Web of Science ®Google Scholar
• ChenLMSongTJXiaoJHHuangZHLiYLinTYTripchlorolide induces autophagy in lung cancer cells by inhibiting the PI3K/AKT/mTOR pathway and improves cisplatin sensitivity in A549/DDP cellsOncotarget2017838639116392228969040
   PubMedGoogle Scholar
• WangZWangNLiuPXieXAMPK and cancerEXS201610720322627812982
   PubMedGoogle Scholar
• UmezawaSHigurashiTNakajimaAAMPK: therapeutic target for diabetes and cancer preventionCurr Pharm Des201723253629364428714409
   PubMed Web of Science ®Google Scholar
• GillsJJDennisPAPerifosine: update on a novel Akt inhibitorCurr Oncol Rep20091110211019216841
   PubMed Web of Science ®Google Scholar
• JankuFMcConkeyDJHongDSKurzrockRAutophagy as a target for anticancer therapyNat Rev Clin Oncol2011852853921587219
   PubMed Web of Science ®Google Scholar
• RubinszteinDCCodognoPLevineBAutophagy modulation as a potential therapeutic target for diverse diseasesNat Rev Drug Discov20121170973022935804
   PubMed Web of Science ®Google Scholar
• MaWGilliganBMYuanJLiTCurrent status and perspectives in translational biomarker research for PD-1/PD-L1 immune checkpoint blockade therapyJ Hematol Oncol201694727234522
   PubMed Web of Science ®Google Scholar
• DholariaBHammondWShredersALouYEmerging therapeutic agents for lung cancerJ Hematol Oncol2016913827938382
   PubMed Web of Science ®Google Scholar
• WangSCangSLiuDThird-generation inhibitors targeting EGFR T790M mutation in advanced non-small cell lung cancerJ Hematol Oncol201693427071706
   PubMed Web of Science ®Google Scholar
• WhiteEKarpCStroheckerAMGuoYMathewRRole of autophagy in suppression of inflammation and cancerCurr Opin Cell Biol20102221221720056400
   PubMed Web of Science ®Google Scholar
• MathewRKarantza-WadsworthVWhiteERole of autophagy in cancerNat Rev Cancer2007796196717972889
   PubMed Web of Science ®Google Scholar
• ApelAHerrISchwarzHRodemannHPMayerABlocked autophagy sensitizes resistant carcinoma cells to radiation therapyCancer Res2008681485149418316613
   PubMed Web of Science ®Google Scholar
• ZhouWLiottaLAPetricoinEFThe Warburg effect and mass spectrometry-based proteomic analysisCancer Genomics Proteomics20171421121828647695
   PubMed Web of Science ®Google Scholar
• HoWLHsuWMHuangMCKadomatsuKNakagawaraAProtein glycosylation in cancers and its potential therapeutic applications in neuroblastomaJ Hematol Oncol2016910027686492
   PubMed Web of Science ®Google Scholar
• LinGHillDKAndrejevaGDichloroacetate induces autophagy in colorectal cancer cells and tumoursBr J Cancer201411137538524892448
   PubMed Web of Science ®Google Scholar
• GongFPengXSangYDichloroacetate induces protective autophagy in LoVo cells: involvement of cathepsin D/thioredoxin-like protein 1 and Akt-mTOR-mediated signalingCell Death Dis20134e91324201812
   PubMed Web of Science ®Google Scholar
• ChouTCTheoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studiesPharmacol Rev20065862168116968952
   PubMed Web of Science ®Google Scholar
• EskelinenELThe dual role of autophagy in cancerCurr Opin Pharmacol20111129430021498118
   PubMed Web of Science ®Google Scholar
• RavikumarBSarkarSDaviesJERegulation of mammalian autophagy in physiology and pathophysiologyPhysiol Rev2010901383143520959619
   PubMed Web of Science ®Google Scholar
• NaveedSAslamMAhmadAStarvation based differential chemotherapy: a novel approach for cancer treatmentOman Med J20142939139825584154
   PubMedGoogle Scholar
• YoshidaGJTherapeutic strategies of drug repositioning targeting autophagy to induce cancer cell death: from pathophysiology to treatmentJ Hematol Oncol2017106728279189
   PubMed Web of Science ®Google Scholar
• ChoiAMRyterSWLevineBAutophagy in human health and diseaseN Engl J Med201336865166223406030
   PubMed Web of Science ®Google Scholar