Paeoniflorin inhibits glioblastoma growth in vivo and in vitro: a role for the Triad3A-dependent ubiquitin proteasome pathway in TLR4 degradation

References

• OmuroADeAngelisLMGlioblastoma and other malignant gliomas: a clinical reviewJAMA20133101842185024193082
   PubMed Web of Science ®Google Scholar
• PreusserMde RibaupierreSWohrerACurrent concepts and management of glioblastomaAnn Neurol20117092121786296
   PubMed Web of Science ®Google Scholar
• AdamsonCKanuOOMehtaAIGlioblastoma multiforme: a review of where we have been and where we are goingExpert Opin Investig Drugs20091810611083
   PubMed Web of Science ®Google Scholar
• OsukaSVan MeirEGOvercoming therapeutic resistance in glioblastoma: the way forwardJ Clin Invest201712741542628145904
   PubMed Web of Science ®Google Scholar
• LinMYChiangSYLiYZAnti-tumor effect of radix paeoniae rubra extract on mice bladder tumors using intravesical therapyOncol Lett20161290491027446367
   PubMed Web of Science ®Google Scholar
• YangNCuiHHanFPaeoniflorin inhibits human pancreatic cancer cell apoptosis via suppression of MMP-9 and RK signalingOncol Lett2016121471147627446455
   PubMed Web of Science ®Google Scholar
• ZhouZWangSSongCPaeoniflorin prevents hypoxia-induced epithelial-mesenchymal transition in human breast cancer cellsOnco Targets Ther201692511251827175085
   PubMed Web of Science ®Google Scholar
• ZhangJYuKHanXPaeoniflorin influences breast cancer cell proliferation and invasion via inhibition of the notch1 signaling pathwayMol Med Rep2018171321132529115554
   PubMed Web of Science ®Google Scholar
• LiYGongLQiRPaeoniflorin suppresses pancreatic cancer cell growth by upregulating HTRA3 expressionDrug Des Devel Ther20171124812491
   PubMed Web of Science ®Google Scholar
• HaoJYangXDingXLPaeoniflorin potentiates the inhibitory effects of erlotinib in pancreatic cancer cell lines by reducing ErbB3 phosphorylationSci Rep201663280927609096
   PubMed Web of Science ®Google Scholar
• ZhengYBXiaoGCTongSLPaeoniflorin inhibits human gastric carcinoma cell proliferation through up-regulation of microrna-124 and suppression of pi3k/akt and stat3 signalingWorld Journal of Gastroenterology2015217197720726109806
   PubMed Web of Science ®Google Scholar
• LiWQiZWeiZPaeoniflorin inhibits proliferation and induces apoptosis of human glioma cells via microRNA-16 upregulation and matrix metalloproteinase-9 downregulationMol Med Rep2015122735274025954855
   PubMed Web of Science ®Google Scholar
• NieXHOu-yangJXingYPaeoniflorin inhibits human glioma cells via STAT3 degradation by the ubiquitin-proteasome pathwayDrug Des Devel Ther2015956115622
   PubMed Web of Science ®Google Scholar
• JiangNXieFGuoQToll-like receptor 4 promotes proliferation and apoptosis resistance in human papillomavirus-related cervical cancer cells through the Toll-like receptor 4/nuclear factor-κB pathwayTumour Biol201739 1010428317710586
   Google Scholar
• SunNKHuangSLChangTCChaoCCTLR4 and NFκB signaling is critical for taxol resistance in ovarian carcinoma cellsJ Cell Physiol20182332489250128771725
   PubMed Web of Science ®Google Scholar
• WangXYuXWangQLuYChenHExpression and clinical significance of SATB1 and TLR4 in breast cancerOncol Lett2017143611361528927120
   PubMed Web of Science ®Google Scholar
• YangXChenGTWangYQTLR4 promotes the expression of HIF-1α by triggering reactive oxygen species in cervical cancer cells in vitro-implications for therapeutic interventionMol Med Rep2017172 2229223829207048
   PubMed Web of Science ®Google Scholar
• CheFYinJQuanYTLR4 interaction with LPS in glioma CD133+ cancer stem cells induces cell proliferation, resistance to chemotherapy and evasion from cytotoxic T lymphocyte-induced cytolysisOncotarget20178534955350728881826
   PubMed Web of Science ®Google Scholar
• LinCKTingCCTsaiWCA tissue microarray study of toll-like receptor 4, decoy receptor 3, and external signal regulated kinase 1/2 expressions in astrocytomaIndian J Pathol Microbiol20165929430027510663
   PubMed Web of Science ®Google Scholar
• SarrazyVVedrenneNBilletFTLR4 signal transduction pathways neutralize the effect of fas signals on glioblastoma cell proliferation and migrationCancer Lett201131119520221852034
   PubMed Web of Science ®Google Scholar
• ZeunerMTKrugerCLVolkKBiased signalling is an essential feature of TLR4 in glioma cellsBiochim Biophys Acta201618633084309527669113
   PubMed Web of Science ®Google Scholar
• LiLLiuYAging-related gene signature regulated by NLRP3 predicts glioma progressionAm J Cancer Res2015544244925628952
   PubMed Web of Science ®Google Scholar
• TarassishinLCasperDLeeSCAberrant expression of interleukin-1β and inflammasome activation in human malignant gliomasPLoS One20149e10343225054228
   PubMed Web of Science ®Google Scholar
• YangFLiuXLiuYMiR-181d/MALT1 regulatory axis attenuates mesenchymal phenotype through NF-κB pathways in glioblastomaCancer Lett20173961928286260
   PubMed Web of Science ®Google Scholar
• LiHJiaoYXieMPaeoniflorin ameliorates atherosclerosis by suppressing TLR4-mediated NF-κB activationInflammation2017402042205128791506
   PubMed Web of Science ®Google Scholar
• ZhangJDouWZhangEPaeoniflorin abrogates dss-induced colitis via a TLR4-dependent pathwayAm J Physiol Gastrointest Liver Physiol2014306G27G3624232001
   PubMed Web of Science ®Google Scholar
• ZhangJLiHHuoRPaeoniflorin selectively inhibits LPS-provoked B-cell functionJ Pharmacol Sci201512881626041080
   PubMed Web of Science ®Google Scholar
• ZhuSHLiuBQHaoMJPaeoniflorin suppressed high glucose-induced retinal microglia MMP-9 expression and inflammatory response via inhibition of TLR4/NF-κB pathway through upregulation of SOCS3 in diabetic retinopathyInflammation2017401475148628639050
   PubMed Web of Science ®Google Scholar
• ZhangTZhuQShaoYPaeoniflorin prevents TLR2/4-mediated inflammation in type 2 diabetic nephropathyBiosci Trends20171130831828626209
   PubMed Web of Science ®Google Scholar
• ChuangT-HUlevitchRJTriad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptorsNat Immunol2004549550315107846
   PubMed Web of Science ®Google Scholar
• FearnsCPanQMathisonJCChuangTHTriad3A regulates ubiquitination and proteasomal degradation of RIP1 following disruption of Hsp90 bindingJ Biol Chem2006281345923460016968706
   PubMed Web of Science ®Google Scholar
• PickartCMMechanisms underlying ubiquitinationAnnu Rev Biochem20017050353311395416
   PubMed Web of Science ®Google Scholar
• CraggGMGrothausPGNewmanDJImpact of natural products on developing new anti-cancer agentsChem Rev20091093012304319422222
   PubMed Web of Science ®Google Scholar
• HassanSTZemlickaMPlant-derived urease inhibitors as alternative chemotherapeutic agentsArch Pharm (Weinheim)201634950752227244041
   PubMed Web of Science ®Google Scholar
• XuHSongJGaoXPaeoniflorin attenuates lipopolysaccharide-induced permeability of endothelial cells: involvements of F-actin expression and phosphorylations of PI3K/AKT and PKCInflammation20133621622523053726
   PubMed Web of Science ®Google Scholar
• ZhengYBXiaoGCTongSLPaeoniflorin inhibits human gastric carcinoma cell proliferation through up-regulation of microRNA-124 and suppression of PI3K/Akt and STAT3 signalingWorld J Gastroenterol2015217197720726109806
   PubMed Web of Science ®Google Scholar
• HeXXingDDingYDetermination of paeoniflorin in rat hippocampus by high-performance liquid chromatography after intravenous administration of paeoniae radix extractJ Chromatogr B Analyt Technol Biomed Life Sci2004802277281
   PubMed Web of Science ®Google Scholar
• CaoCHeXWangWKinetic distribution of paeoniflorin in cortex of normal and cerebral ischemia-reperfusion rats after intravenous administration of paeoniae radix extractBiomedical Chromatography2006201283128817006964
   PubMed Web of Science ®Google Scholar
• BaumanTMBeckaAJSehgalPDSIGIRR/TIR8, an important regulator of TLR4 and IL-1R-mediated NF-κB activation, predicts biochemical recurrence after prostatectomy in low-grade prostate carcinomasHum Pathol2015461744175126344417
   PubMed Web of Science ®Google Scholar
• XingYCaoRHuHMTLR and NLRP3 inflammasome-dependent innate immune responses to tumor-derived autophagosomes (DRibbles)Cell Death Dis20167e232227490927
   PubMed Web of Science ®Google Scholar