62
Views
4
CrossRef citations to date
0
Altmetric
Original Research

Epidermal growth factor receptor gene mutations in non-small-cell lung cancer cells are associated with increased radiosensitivity in vitro

, , , , &
Pages 3551-3560 | Published online: 13 Sep 2018

References

  • MolinaJRYangPCassiviSDSchildSEAdjeiAANon-small cell lung cancer: epidemiology, risk factors, treatment, and survivorshipMayo Clin Proc200883558459418452692
  • HaslettKPöttgenCStuschkeMFaivre-FinnCHyperfractionated and accelerated radiotherapy in non-small cell lung cancerJ Thorac Dis20146432833524688777
  • CurranWJPaulusRLangerCJSequential vs. concurrent chemo-radiation for stage III non-small cell lung cancer: randomized phase III trial RTOG 9410J Natl Cancer Inst2011103191452146021903745
  • DasAKBellMHNirodiCSStoryMDMinnaJDRadiogenomics predicting tumor responses to radiotherapy in lung cancerSemin Radiat Oncol201020314915520685577
  • MitsudomiTMoritaSYatabeYGefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trialLancet Oncol201011212112820022809
  • MidhaADeardenSMccormackREGFR mutation incidence in non-small-cell lung cancer of adenocarcinoma histology: a systematic review and global map by ethnicity (mutMapII)Am J Cancer Res2015592892291126609494
  • SoriaJCWuYLNakagawaKGefitinib plus chemotherapy versus placebo plus chemotherapy in EGFR-mutation-positive non-small-cell lung cancer after progression on first-line gefitinib (IMPRESS): a phase 3 randomised trialLancet Oncol201516899099826159065
  • SequistLVYangJCYamamotoNPhase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutationsJ Clin Oncol201331273327333423816960
  • LeeDWShinDYKimJWAdditional prognostic role of EGFR activating mutations in lung adenocarcinoma patients with brain metastasis: integrating with lung specific GPA scoreLung Cancer201486336336825453849
  • WangTJSaadSQureshiYHDoes lung cancer mutation status and targeted therapy predict for outcomes and local control in the setting of brain metastases treated with radiation?Neuro Oncol20151771022102825910841
  • DasAKSatoMStoryMDNon-small-cell lung cancers with kinase domain mutations in the epidermal growth factor receptor are sensitive to ionizing radiationCancer Res200666199601960817018617
  • OweidaASharifiZHalabiHDifferential response to ablative ionizing radiation in genetically distinct non-small cell lung cancer cellsCancer Biol Ther201617439039927096542
  • ChapmanJDGillespieCJThe power of radiation biophysics-let’s use itInt J Radiat Oncol Biol Phys201284230931122935394
  • IvashkevichARedonCENakamuraAJMartinRFMartinOAUse of the γ-H2AX assay to monitor DNA damage and repair in translational cancer researchCancer Lett20123271–212313322198208
  • LynchTJBellDWSordellaRActivating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinibN Engl J Med2004350212129213915118073
  • PaoWMillerVZakowskiMEGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinibProc Natl Acad Sci U S A200410136133061331115329413
  • BokobzaSMJiangYWeberAMDeveryAMRyanAJShort-course treatment with gefitinib enhances curative potential of radiation therapy in a mouse model of human non-small cell lung cancerInt J Radiat Oncol Biol Phys201488494795424606853
  • LeeHLChungTSTingLLEGFR mutations are associated with favorable intracranial response and progression-free survival following brain irradiation in non-small cell lung cancer patients with brain metastasesRadiat Oncol2012718123110940
  • MakRHDoranEMuzikanskyAOutcomes after combined modality therapy for EGFR-mutant and wild-type locally advanced NSCLCOncologist201116688689521632451
  • BalakMNGongYRielyGJNovel D761Y and common secondary T790M mutations in epidermal growth factor receptor-mutant lung adenocarcinomas with acquired resistance to kinase inhibitorsClin Cancer Res200612216494650117085664
  • BethuneGBethuneDRidgwayNXuZEpidermal growth factor receptor (EGFR) in lung cancer: an overview and updateJ Thorac Dis201021485122263017
  • FrancoSMurphyMMLiGDNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombinationJ Exp Med2008205355756418316419
  • GurleyKEMoserRGuYHastyPKempCJDNA-PK suppresses a p53-independent apoptotic response to DNA damageEMBO Rep2009101879319057578
  • ChenDJNirodiCSThe epidermal growth factor receptor: a role in repair of radiation-induced DNA damageClin Cancer Res20071322 Pt 16555656018006754
  • LiccardiGHartleyJAHochhauserDEGFR nuclear translocation modulates DNA repair following cisplatin and ionizing radiation treatmentCancer Res20117131103111421266349
  • StrasserAHarrisAWJacksTCorySDNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2Cell19947923293397954799
  • NowsheenSYangESThe intersection between DNA damage response and cell death pathwaysExp Oncol201234324325423070009
  • PlescaDMazumderSAlmasanADNA damage response and apoptosisMethods Enzymol200844610712218603118
  • WangJPablaNWangCYCaspase-mediated cleavage of ATM during cisplatin-induced tubular cell apoptosis: inactivation of its kinase activity toward p53Am J Physiol Renal Physiol20062916F1300F130716849690