References
- SiegelRLMillerKDJemalACancer statistics, 2018CA Cancer J Clin201868173029313949
- PritzkerKPPredictive and prognostic cancer biomarkers revisitedExpert Rev Mol Diagn201515897197426134385
- FukushimaSTerasakiMSakataKSensitivity and usefulness of anti-phosphohistone-H3 antibody immunostaining for counting mitotic figures in meningioma casesBrain Tumor Pathol2009262515719856215
- ChadeeDNHendzelMJTylipskiCPIncreased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblastsJ Biol Chem199927435249142492010455166
- ChoiHSChoiBYChoYYPhosphorylation of histone H3 at serine 10 is indispensable for neoplastic cell transformationCancer Res200565135818582715994958
- IbukiYToyookaTZhaoXYoshidaICigarette sidestream smoke induces histone H3 phosphorylation via JNK and PI3K/Akt pathways, leading to the expression of proto-oncogenesCarcinogenesis20143561228123724398671
- LiBHuangGZhangXIncreased phosphorylation of histone H3 at serine 10 is involved in Epstein-Barr virus latent membrane protein-1-induced carcinogenesis of nasopharyngeal carcinomaBMC Cancer20131312423496845
- ZhuPZhangCBYangPPhosphohistone H3 (pHH3) is a prognostic and epithelial to mesenchymal transition marker in diffuse gliomasOncotarget2016729450054501427323851
- GoltzDMontaniMBraunMPrognostic relevance of proliferation markers (Ki-67, PHH3) within the cross-relation of ERG translocation and androgen receptor expression in prostate cancerPathology201547762963626517642
- GudlaugssonESkalandIUndersrudEJanssenEASoilandHBaakJPD2-40/p63 defined lymph vessel invasion has additional prognostic value in highly proliferating operable node negative breast cancer patientsMod Pathol201124450251121317878
- AlkhasawnehAReithJDToroTZInterobserver variability of mitotic index and utility of PHH3 for risk stratification in gastrointestinal stromal tumorsAm J Clin Pathol2015143338539225696796
- StangACritical evaluation of the Newcastle–Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analysesEur J Epidemiol201025960360520652370
- ChowKLTseKYCheungCLThe mitosis-specific marker phosphohistone-H3 (PHH3) is an independent prognosticator in uterine smooth muscle tumours: an outcome-based studyHistopathology201770574675527864989
- XuHExpression of EN2, PHH3 in Prostate Cancer and Prognostic Significance [master’s thesis]TaiyuanShanxi Medical University2014
- KimJYJeongHSChungTThe value of phosphohistone H3 as a proliferation marker for evaluating invasive breast cancers: a comparative study with Ki67Oncotarget2017839650646507629029412
- WintherTLArnliMBSalvesenØTorpSHPhosphohistone-H3 proliferation index is superior to mitotic index and MIB-1 expression as a predictor of recurrence in human meningiomasAm J Clin Pathol2016146451052027686177
- GudlaugssonEKlosJSkalandIPrognostic comparison of the proliferation markers (mitotic activity index, phosphohistone H3, Ki67), steroid receptors, HER2, high molecular weight cytokeratins and classical prognostic factors in T(1)(-)(2)N(0)M(0) breast cancerPol J Pathol20136411823625593
- LadsteinRGBachmannIMStraumeOAkslenLAPrognostic importance of the mitotic marker phosphohistone H3 in cutaneous nodular melanomaJ Invest Dermatol201213241247125222297638
- KhanSAAmnekarRKhadeBp38-MAPK/MSK1-mediated overexpression of histone H3 serine 10 phosphorylation defines distance-dependent prognostic value of negative resection margin in gastric cancerClin Epigenetics201688827588146
- KimYJKetterRSteudelWIFeidenWPrognostic significance of the mitotic index using the mitosis marker anti-phosphohistone H3 in meningiomasAm J Clin Pathol2007128111812517580279
- IwasakiTMatsushitaMNonakaDPhosphohistone-H3 (PHH3) is prognostic relevant in Merkel cell carcinomas but Merkel cell polyomavirus is a more powerful prognostic factor than AJCC clinical stage, PHH3, Ki-67 or mitotic indicesPathol Int201565840440925982855
- RamaniPTaylorSMillerESowa-AvugrahEMayMTHigh phosphohistone H3 expression correlates with adverse clinical, biological, and pathological factors in neuroblastomasJ Histochem Cytochem201563639740725711230
- OlarAWaniKMSulmanEPMitotic index is an independent predictor of recurrence-free survival in meningiomaBrain Pathol201525326627525040885
- GerringZPearsonJFMorrinHRRobinsonBAHarrisGCWalkerLCPhosphohistone H3 outperforms Ki67 as a marker of outcome for breast cancer patientsHistopathology201567453854725728258
- KlintmanMStrandCAhlinCThe prognostic value of mitotic activity index (MAI), phosphohistone H3 (PPH3), cyclin B1, cyclin A, and Ki67, alone and in combinations, in node-negative premenopausal breast cancerPLoS One2013812e8190224324728
- BrunnerARissPHeinzeGBrustmannHpHH3 and survivin are co-expressed in high-risk endometrial cancer and are prognostic relevantBr J Cancer20121071849022644303
- DuregonEMolinaroLVolanteMComparative diagnostic and prognostic performances of the hematoxylin-eosin and phospho-histone H3 mitotic count and Ki-67 index in adrenocortical carcinomaMod Pathol20142791246125424434900
- SkalandIJanssenEAGudlaugssonEHui Ru GuoLBaakJPThe prognostic value of the proliferation marker phosphohistone H3 (PPH3) in luminal, basal-like and triple negative phenotype invasive lymph node-negative breast cancerCell Oncol200931426127119633363
- SkalandIJanssenEAGudlaugssonEPhosphohistone H3 expression has much stronger prognostic value than classical prognosticators in invasive lymph node-negative breast cancer patients <55 years of ageMod Pathol200720121307131517917671
- TakeiHBhattacharjeeMBRiveraADancerYPowellSZNew immunohistochemical markers in the evaluation of central nervous system tumors: a review of 7 selected adult and pediatric brain tumorsArch Pathol Lab Med2007131223424117284108
- TakahashiHMuraiYTsuneyamaKOverexpression of phosphorylated histone H3 is an indicator of poor prognosis in gastric adenocarcinoma patientsAppl Immunohistochem Mol Morphol200614329630216932020
- BrennerRMSlaydenODRodgersWHImmunocytochemical assessment of mitotic activity with an antibody to phosphorylated histone H3 in the macaque and human endometriumHum Reprod20031861185119312773444
- SambrookJRussellDWDephosphorylation of plasmid DNA.CSH Protoc200620061
- AliHRDawsonSJBlowsFMProvenzanoEPharoahPDCaldasCAurora kinase A outperforms Ki67 as a prognostic marker in ER-positive breast cancerBr J Cancer2012106111798180622538974
- JonsdottirKAssmusJSlewaAPrognostic value of gene signatures and proliferation in lymphnode-negative breast cancerPLoS One201493e9064224599057
- NowakMSvenssonMACarlssonJPrognostic significance of phospho-histone H3 in prostate carcinomaWorld J Urol201432370370723887713
- GotoHTomonoYAjiroKIdentification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensationJ Biol Chem199927436255432554910464286
- JuanGTraganosFDarzynkiewiczZHistone H3 phosphorylation in human monocytes and during HL-60 cell differentiationExp Cell Res199924612122209882530
- SunAZhouWLuncefordJStrackPDauffenbachLMKerfootCALevel of phosphohistone H3 among various types of human cancersBMJ Open201225e001071
- BossardCJarryAColombeixCPhosphohistone H3 labelling for histoprognostic grading of breast adenocarcinomas and computer-assisted determination of mitotic indexJ Clin Pathol200659770671016461563
- RibaltaTMcCutcheonIEAldapeKDBrunerJMFullerGNThe mitosis-specific antibody anti-phosphohistone-H3 (PHH3) facilitates rapid reliable grading of meningiomas according to WHO 2000 criteriaAm J Surg Pathol200428111532153615489659
- SkalandIJanssenEAGudlaugssonEValidating the prognostic value of proliferation measured by phosphohistone H3 (PPH3) in invasive lymph node-negative breast cancer patients <71 years of ageBreast Cancer Res Treat20091141394518373192
- ScottISHeathTMMorrisLSA novel immunohistochemical method for estimating cell cycle phase distribution in ovarian serous neoplasms: implications for the histopathological assessment of paraffin-embedded specimensBr J Cancer20049081583159015083189