References
- SiegelRLMillerKDJemalACancer statistics, 2016CA Cancer J Clin201666173026742998
- ChenWZhengRBaadePDCancer statistics in China, 2015CA Cancer J Clin201666211513226808342
- CersosimoRJManagement of advanced colorectal cancer, Part 1Am J Health Syst Pharm201370539540623413162
- MurilloGPengXTorresKEMehtaRGDeguelin inhibits growth of breast cancer cells by modulating the expression of key members of the Wnt signaling pathwayCancer Prev Res (Phila)200921194295019861542
- LeeHYOhSHWooJKChemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesisJ Natl Cancer Inst200597221695169916288123
- YanBZhaoDYaoYBaoZLuGZhouJDeguelin Induces the Apoptosis of Lung Squamous Cell Carcinoma Cells through Regulating the Expression of Galectin-1Int J Biol Sci201612785086027313498
- BoreddySRSrivastavaSKDeguelin suppresses pancreatic tumor growth and metastasis by inhibiting epithelial-to-mesenchymal transition in an orthotopic modelOncogene201332343980399122986522
- LeeHYSuhYAKosmederJWPezzutoJMHongWKKurieJMDeguelin-induced inhibition of cyclooxygenase-2 expression in human bronchial epithelial cellsClin Cancer Res20041031074107914871987
- MemmottRMDennisPAThe role of the Akt/mTOR pathway in tobacco carcinogen-induced lung tumorigenesisClin Cancer Res201016141020028747
- OhSHWooJKJinQIdentification of novel antiangiogenic anticancer activities of deguelin targeting hypoxia-inducible factor-1 alphaInt J Cancer2008122151417764071
- SuhYAKimJHSungMAA novel antitumor activity of deguelin targeting the insulin-like growth factor (IGF) receptor pathway via up-regulation of IGF-binding protein-3 expression in breast cancerCancer Lett2013332110210923348700
- KangHWKimJMChaMYJungHCSongISKimJSDeguelin, an Akt inhibitor, down-regulates NF-κB signaling and induces apoptosis in colon cancer cells and inhibits tumor growth in miceDig Dis Sci201257112873288222623043
- JinQMenterDGMaoLHongWKLeeHYSurvivin expression in normal human bronchial epithelial cells: an early and critical step in tumorigenesis induced by tobacco exposureCarcinogenesis20082981614162218635526
- LooDTIn situ detection of apoptosis by the TUNEL assay: an overview of techniquesMethods Mol Biol201168231321057916
- OlsonJMHallahanARp38 MAP kinase: a convergence point in cancer therapyTrends Mol Med200410312512915102355
- CuadradoANebredaARMechanisms and functions of p38 MAPK signallingBiochem J2010429340341720626350
- XiaYShenSVermaIMNF-κB, an active player in human cancersCancer Immunol Res20142982383025187272
- HsuYCChiangJHYuCSAntitumor effects of deguelin on H460 human lung cancer cells in vitro and in vivo: Roles of apoptotic cell death and H460 tumor xenografts modelEnviron Toxicol2017321849826592500
- MarianiMZannoniGFSioleticSGender influences the class III and V β-tubulin ability to predict poor outcome in colorectal cancerClin Cancer Res201218102964297522438565
- TammIWangYSausvilleEIAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugsCancer Res19985823531553209850056
- CorySAdamsJMThe Bcl2 family: regulators of the cellular life-or-death switchNat Rev Cancer20022964765612209154
- AdamsJMCorySThe Bcl-2 apoptotic switch in cancer development and therapyOncogene20072691324133717322918
- MerinoDLokSWVisvaderJELindemanGJTargeting BCL-2 to enhance vulnerability to therapy in estrogen receptor-positive breast cancerOncogene201635151877188726257067
- BelmokhtarCAHillionJSégal-BendirdjianEStaurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanismsOncogene200120263354336211423986
- Pozo-GuisadoEMerinoJMMulero-NavarroSResveratrol-induced apoptosis in MCF-7 human breast cancer cells involves a caspase-independent mechanism with downregulation of Bcl-2 and NF-kappaBInt J Cancer20051151748415688415
- GrossiVPesericoATezilTSimoneCp38α MAPK pathway: a key factor in colorectal cancer therapy and chemoresistanceWorld J Gastroenterol201420299744975825110412
- ShinDYLeeWSLuJNInduction of apoptosis in human colon cancer HCT-116 cells by anthocyanins through suppression of Akt and activation of p38-MAPKInt J Oncol2009356149950419885574
- PangHCaiLYangYChenXSuiGZhaoCKnockdown of osteopontin chemosensitizes MDA-MB-231 cells to cyclophosphamide by enhancing apoptosis through activating p38 MAPK pathwayCancer Biother Radiopharm201126216517321539449
- LouXZhouQYinYZhouCShenYInhibition of the met receptor tyrosine kinase signaling enhances the chemosensitivity of glioma cell lines to CDDP through activation of p38 MAPK pathwayMol Cancer Ther2009851126113619435873
- GanLWangJXuHYangXResistance to docetaxel-induced apoptosis in prostate cancer cells by p38/p53/p21 signalingProstate201171111158116621656826
- PereiraLIgeaACanovasBDoladoINebredaARInhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNKEMBO Mol Med20135111759177424115572