68
Views
16
CrossRef citations to date
0
Altmetric
Original Research

The role of autophagy in the radiosensitivity of the radioresistant human nasopharyngeal carcinoma cell line CNE-2R

, , , , , & show all
Pages 4125-4134 | Published online: 02 Oct 2018

References

  • TorreLABrayFSiegelRLFerlayJLortet-TieulentJJemalAGlobal cancer statistics, 2012CA Cancer J Clin20156528710825651787
  • TangLLChenWQXueWQGlobal trends in incidence and mortality of nasopharyngeal carcinomaCancer Lett20163741223026828135
  • AuKHNganRKCNgAWYTreatment outcomes of nasopharyngeal carcinoma in modern era after intensity modulated radiotherapy (IMRT) in Hong Kong: A report of 3328 patients (HKNPCSG 1301 studyOral Oncol201877162129362121
  • LeeAWMaBBNgWTChanATManagement of Nasopharyngeal Carcinoma: Current Practice and Future PerspectiveJ Clin Oncol201533293356336426351355
  • KongFYingHduCPatterns of local-regional failure after primary intensity modulated radiotherapy for nasopharyngeal carcinomaRadiat Oncol201496024552293
  • LiYQTianYMTanSHPrognostic Model for Stratification of Radioresistant Nasopharynx Carcinoma to Curative Salvage RadiotherapyJ Clin Oncol201836989189929412781
  • HönscheidPDattaKMudersMHAutophagy: detection, regulation and its role in cancer and therapy responseInt J Radiat Biol201490862863524678799
  • LiYQTianYMTanSHReducing autophagy and inducing G1 phase arrest by aloperine enhances radio-sensitivity in lung cancer cellsOncol Rep2017
  • PengWXWanYYGongAHEgr-1 regulates irradiation-induced autophagy through Atg4B to promote radioresistance in hepatocellular carcinoma cellsOncogenesis201761e29228134935
  • HuJLHeGYLanXLInhibition of ATG12-mediated autophagy by miR-214 enhances radiosensitivity in colorectal cancerOncogenesis2018721629459645
  • ZhouZRZhuXDZhaoWPoly(ADP-ribose) polymerase-1 regulates the mechanism of irradiation-induced CNE-2 human nasopharyngeal carcinoma cell autophagy and inhibition of autophagy contributes to the radiation sensitization of CNE-2 cellsOncol Rep20132962498250623563481
  • GuoYZhuXDQuSIdentification of genes involved in radioresistance of nasopharyngeal carcinoma by integrating gene ontology and protein-protein interaction networksInt J Oncol2012401859221874234
  • GuoSI-YANZhuX-DGeL-YRNAi-mediated knockdown of the c-jun gene sensitizes radioresistant human nasopharyngeal carcinoma cell line CNE-2R to radiationOncol Rep20153331155116025571870
  • LinHChenZTZhuXDSerum CD166: A novel biomarker for predicting nasopharyngeal carcinoma response to radiotherapyOncotarget2017838628586286728968954
  • JiangPMizushimaNLC3- and p62-based biochemical methods for the analysis of autophagy progression in mammalian cellsMethods201575131825484342
  • SchläfliAMBerezowskaSAdamsOLangerRTschanMPReliable LC3 and p62 autophagy marker detection in formalin fixed paraffin embedded human tissue by immunohistochemistryEur J Histochem2015592248126150155
  • XinYJiangFYangCRole of autophagy in regulating the radiosensitivity of tumor cellsJ Cancer Res Clin Oncol2017143112147215728786037
  • dasCKMandalMKögelDPro-survival autophagy and cancer cell resistance to therapyCancer Metastasis Rev2018
  • ZhuangWLiBLongLChenLHuangQLiangZInduction of autophagy promotes differentiation of glioma-initiating cells and their radiosensitivityInt J Cancer2011129112720273121384342
  • ZhangXJiJYangYZhangJShenLStathmin1 increases radioresistance by enhancing autophagy in non-small-cell lung cancer cellsOnco Targets Ther201692565257427199567
  • YeHChenMCaoFHuangHZhanRZhengXChloroquine, an autophagy inhibitor, potentiates the radiosensitivity of glioma initiating cells by inhibiting autophagy and activating apoptosisBMC Neurol201616117827644442
  • KaurASharmaSMammalian target of rapamycin (mTOR) as a potential therapeutic target in various diseasesInflammopharmacology201725329331228417246
  • RubinszteinDCCodognoPLevineBAutophagy modulation as a potential therapeutic target for diverse diseasesNat Rev Drug Discov201211970973022935804
  • Avniel-PolakSLeibowitzGRiahiYGlaserBGrossDJGrozinsky-GlasbergSAbrogation of Autophagy by Chloroquine Alone or in Combination with mTOR Inhibitors Induces Apoptosis in Neuroendocrine Tumor CellsNeuroendocrinology2016103672473726619207
  • GoldenEBChoHYJahanianAChloroquine enhances temozolomide cytotoxicity in malignant gliomas by blocking autophagyNeurosurg Focus2014376E12
  • LiuQThoreenCWangJSabatiniDGrayNSmTOR Mediated Anti-Cancer Drug DiscoveryDrug Discov Today Ther Strateg200962475520622997
  • WeichhartTMammalian target of rapamycin: a signaling kinase for every aspect of cellular lifeMethods Mol Biol201282111422125056
  • LiYLiuFWangYRapamycin-induced autophagy sensitizes A549 cells to radiation associated with DNA damage repair inhibitionThorac Cancer20167437938627385978
  • WangFTangJLiPChloroquine Enhances the Radiosensitivity of Bladder Cancer Cells by Inhibiting Autophagy and Activating ApoptosisCell Physiol Biochem2018451546629316551
  • DaiZ-JGaoJMaX-BAntitumor effects of rapamycin in pancreatic cancer cells by inducing apoptosis and autophagyInt J Mol Sci201214127328523344033