Exosomes derived from rAAV/AFP-transfected dendritic cells elicit specific T cell-mediated immune responses against hepatocellular carcinoma

References

• FerlayJSoerjomataramIDikshitRCancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012Int J Cancer20151365E359E38625220842
   PubMed Web of Science ®Google Scholar
• GBD 2015 Mortality and Causes of Death CollaboratorsGlobal, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015Lancet2016388100531459154427733281
   PubMed Web of Science ®Google Scholar
• FornerALlovetJMBruixJHepatocellular carcinomaLancet201237998221245125522353262
   PubMed Web of Science ®Google Scholar
• MendizabalMReddyKRCurrent management of hepatocellular carcinomaMed Clin North Am200993488590019577120
   PubMed Web of Science ®Google Scholar
• AkoadMEPomfretEASurgical resection and liver transplantation for hepatocellular carcinomaClin Liver Dis201519238139925921669
   PubMed Web of Science ®Google Scholar
• BruixJShermanMPractice Guidelines Committee, American Association for the Study of Liver DiseasesManagement of hepatocellular carcinomaHepatology20054251208123616250051
   PubMed Web of Science ®Google Scholar
• BruixJLlovetJMCastellsATransarterial embolization versus symptomatic treatment in patients with advanced hepatocellular carcinoma: results of a randomized, controlled trial in a single institutionHepatology1998276157815839620330
   PubMed Web of Science ®Google Scholar
• MorimotoMSugimoriKShiratoKTreatment of hepatocellular carcinoma with radiofrequency ablation: radiologic-histologic correlation during follow-up periodsHepatology20023561467147512029632
   PubMed Web of Science ®Google Scholar
• LlovetJMBruixJMolecular targeted therapies in hepatocellular carcinomaHepatology20084841312132718821591
   PubMed Web of Science ®Google Scholar
• StotzMGergerAHaybaeckJKiesslichTBullockMDPichlerMMolecular targeted therapies in hepatocellular carcinoma: past, present and futureAnticancer Res201535115737574426503994
   PubMed Web of Science ®Google Scholar
• SangiovanniAColomboMTreatment of hepatocellular carcinoma: beyond international guidelinesLiver Int201636Suppl 112412926725909
   PubMedGoogle Scholar
• PrietoJMeleroISangroBImmunological landscape and immunotherapy of hepatocellular carcinomaNat Rev Gastroenterol Hepatol2015121268170026484443
   PubMed Web of Science ®Google Scholar
• FinnOJCancer immunologyN Engl J Med2008358252704271518565863
   PubMed Web of Science ®Google Scholar
• RosenbergSAYangJCRestifoNPCancer immunotherapy: moving beyond current vaccinesNat Med200410990991515340416
   PubMed Web of Science ®Google Scholar
• TopalianSLWeinerGJPardollDMCancer immunotherapy comes of ageJ Clin Oncol201129364828483622042955
   PubMed Web of Science ®Google Scholar
• SturmJWKeeseMMultimodal treatment of hepatocellular carcinoma (HCC)Onkologie200427329430315249721
   PubMedGoogle Scholar
• BreousEThimmeRPotential of immunotherapy for hepatocellular carcinomaJ Hepatol201154483083421145836
   PubMed Web of Science ®Google Scholar
• VegliaFGabrilovichDIDendritic cells in cancer: the role revisitedCurr Opin Immunol201745435128192720
   PubMed Web of Science ®Google Scholar
• GabrilovichDICiernikIFCarboneDPDendritic cells in antitumor immune responses. I. Defective antigen presentation in tumor-bearing hostsCell Immunol199617011011108665590
   PubMed Web of Science ®Google Scholar
• ApetohLLocherCGhiringhelliFKroemerGZitvogelLHarnessing dendritic cells in cancerSemin Immunol2011231424921295491
   PubMed Web of Science ®Google Scholar
• ColacoCADC-based cancer immunotherapy: the sequelImmunol Today199920419719810203720
   PubMedGoogle Scholar
• GilboaEDC-based cancer vaccinesJ Clin Invest200711751195120317476349
   PubMed Web of Science ®Google Scholar
• GilboaENairSKLyerlyHKImmunotherapy of cancer with dendritic-cell-based vaccinesCancer Immunol Immunother199846282879558003
   PubMed Web of Science ®Google Scholar
• HradilovaNSadilkovaLPalataOGeneration of dendritic cell-based vaccine using high hydrostatic pressure for non-small cell lung cancer immunotherapyPLoS One2017122e017153928187172
   PubMed Web of Science ®Google Scholar
• UmSJChoiYJShinHJPhase I study of autologous dendritic cell tumor vaccine in patients with non-small cell lung cancerLung Cancer201070218819420223553
   PubMed Web of Science ®Google Scholar
• ShimizuKKoteraYArugaATakeshitaNTakasakiKYamamotoMClinical utilization of postoperative dendritic cell vaccine plus activated T-cell transfer in patients with intrahepatic cholangiocarcinomaJ Hepatobiliary Pancreat Sci201219217117821874278
   PubMed Web of Science ®Google Scholar
• MarksEIYeeNSImmunotherapeutic approaches in biliary tract carcinoma: Current status and emerging strategiesWorld J Gastrointest Oncol201571133834626600933
   PubMed Web of Science ®Google Scholar
• NaritaMKandaTAbeTImmune responses in patients with esophageal cancer treated with SART1 peptide-pulsed dendritic cell vaccineInt J Oncol20154641699170925625346
   PubMed Web of Science ®Google Scholar
• ZhuHYangXLiJImmune response, safety, and survival and quality of life outcomes for advanced colorectal cancer patients treated with dendritic cell vaccine and cytokine-induced killer cell therapyBiomed Res Int20142014603871525136601
   PubMed Web of Science ®Google Scholar
• BurgdorfSKFischerAMyschetzkyPSClinical responses in patients with advanced colorectal cancer to a dendritic cell based vaccineOncol Rep20082061305131119020707
   PubMed Web of Science ®Google Scholar
• SunTYYanWYangCMClinical research on dendritic cell vaccines to prevent postoperative recurrence and metastasis of liver cancerGenet Mol Res2015144162221623226662415
   PubMed Web of Science ®Google Scholar
• ShimizuKKoteraYArugaAPostoperative dendritic cell vaccine plus activated T-cell transfer improves the survival of patients with invasive hepatocellular carcinomaHum Vaccin Immunother201410497097624419174
   PubMed Web of Science ®Google Scholar
• El AnsaryMMogawerSElhamidSAImmunotherapy by autologous dendritic cell vaccine in patients with advanced HCCJ Cancer Res Clin Oncol20131391394822886490
   PubMed Web of Science ®Google Scholar
• QiCJNingYLHanYSAutologous dendritic cell vaccine for estrogen receptor (ER)/progestin receptor (PR) double-negative breast cancerCancer Immunol Immunother20126191415142422290073
   PubMed Web of Science ®Google Scholar
• GelaoLCriscitielloCEspositoADendritic cell-based vaccines: clinical applications in breast cancerImmunotherapy20146334936024762078
   PubMed Web of Science ®Google Scholar
• LópezMNPeredaCSegalGProlonged survival of dendritic cell-vaccinated melanoma patients correlates with tumor-specific delayed type IV hypersensitivity response and reduction of tumor growth factor beta-expressing T cellsJ Clin Oncol200927694595219139436
   PubMed Web of Science ®Google Scholar
• NakaiNHartmannGKishimotoSKatohNDendritic cell vaccination in human melanoma: relationships between clinical effects and vaccine parametersPigment Cell Melanoma Res201023560761920579307
   PubMed Web of Science ®Google Scholar
• GargADVandenberkLKoksCDendritic cell vaccines based on immunogenic cell death elicit danger signals and T cell-driven rejection of high-grade gliomaSci Transl Med20168328:ra27
   Web of Science ®Google Scholar
• LiMHanSShiXIn situ dendritic cell vaccination for the treatment of glioma and literature reviewTumour Biol20163721797180126318301
   PubMedGoogle Scholar
• PalSKHuAFiglinRAA new age for vaccine therapy in renal cell carcinomaCancer J201319436537023867519
   PubMed Web of Science ®Google Scholar
• WangJLiaoLTanJDendritic cell-based vaccination for renal cell carcinoma: challenges in clinical trialsImmunotherapy20124101031104223148755
   PubMed Web of Science ®Google Scholar
• KongstedPBorchTHEllebaekEDendritic cell vaccination in combination with docetaxel for patients with metastatic castration-resistant prostate cancer: A randomized phase II studyCytotherapy201719450051328215654
   PubMed Web of Science ®Google Scholar
• ReyesDSalazarLEspinozaETumour cell lysate-loaded dendritic cell vaccine induces biochemical and memory immune response in castration-resistant prostate cancer patientsBr J Cancer201310961488149723989944
   PubMed Web of Science ®Google Scholar
• TanyiJLChuCSDendritic cell-based tumor vaccinations in epithelial ovarian cancer: a systematic reviewImmunotherapy2012410995100923148752
   PubMed Web of Science ®Google Scholar
• CannonMJGoyneHStonePJChiriva-InternatiMDendritic cell vaccination against ovarian cancer–tipping the Treg/TH17 balance to therapeutic advantage?Expert Opin Biol Ther201111444144521271951
   PubMed Web of Science ®Google Scholar
• CuiYYangXZhuWLiJWuXPangYImmune response, clinical outcome and safety of dendritic cell vaccine in combination with cytokine-induced killer cell therapy in cancer patientsOncol Lett20136253754124137363
   PubMed Web of Science ®Google Scholar
• AnguilleSSmitsELLionEvan TendelooVFBernemanZNClinical use of dendritic cells for cancer therapyLancet Oncol2014157e257e26724872109
   PubMed Web of Science ®Google Scholar
• ButlerJSThe yin and yang of the exosomeTrends Cell Biol2002122909611849973
   PubMed Web of Science ®Google Scholar
• AzmiASBaoBSarkarFHExosomes in cancer development, metastasis, and drug resistance: a comprehensive reviewCancer Metastasis Rev2013323–462364223709120
   PubMed Web of Science ®Google Scholar
• SrivastavaAFilantJMoxleyKMSoodAMcMeekinSRameshRExosomes: a role for naturally occurring nanovesicles in cancer growth, diagnosis and treatmentCurr Gene Ther201515218219225537774
   PubMed Web of Science ®Google Scholar
• TaïebJChaputNZitvogelLDendritic cell-derived exosomes as cell-free peptide-based vaccinesCrit Rev Immunol200525321522316048436
   PubMed Web of Science ®Google Scholar
• PittJMAndréFAmigorenaSDendritic cell-derived exosomes for cancer therapyJ Clin Invest201612641224123227035813
   PubMed Web of Science ®Google Scholar
• PittJMCharrierMViaudSDendritic cell-derived exosomes as immunotherapies in the fight against cancerJ Immunol201419331006101125049431
   PubMed Web of Science ®Google Scholar
• ViaudSTermeMFlamentCDendritic cell-derived exosomes promote natural killer cell activation and proliferation: a role for NKG2D ligands and IL-15RalphaPLoS One200943e494219319200
   PubMed Web of Science ®Google Scholar
• BrodyJDEnglemanEGDC-based cancer vaccines: lessons from clinical trialsCytotherapy20046212212715203988
   PubMed Web of Science ®Google Scholar
• ZhouJMaPLiJSongWComparative analysis of cytotoxic T lymphocyte response induced by dendritic cells pulsed with recombinant adeno-associated virus carrying α-fetoprotein gene or cancer cell lysateMol Med Rep20151143174318025484119
   PubMed Web of Science ®Google Scholar
• GiaccaMZacchignaSVirus-mediated gene delivery for human gene therapyJ Control Release2012161237738822516095
   PubMed Web of Science ®Google Scholar
• BiancoNRKimSHMorelliAERobbinsPDModulation of the immune response using dendritic cell-derived exosomesMethods Mol Biol200738044345517876111
   PubMedGoogle Scholar
• ZitvogelLRegnaultALozierAEradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomesNat Med1998455946009585234
   PubMed Web of Science ®Google Scholar
• YinWOuyangSLiYXiaoBYangHImmature dendritic cell-derived exosomes: a promise subcellular vaccine for autoimmunityInflammation201336123224022956173
   PubMed Web of Science ®Google Scholar
• SeguraEAmigorenaSThéryCMature dendritic cells secrete exosomes with strong ability to induce antigen-specific effector immune responsesBlood Cells Mol Dis2005352899315990342
   PubMed Web of Science ®Google Scholar
• Utsugi-KobukaiSFujimakiHHottaCNakazawaMMinamiMMHC class I-mediated exogenous antigen presentation by exosomes secreted from immature and mature bone marrow derived dendritic cellsImmunol Lett2003892–312513114556969
   PubMed Web of Science ®Google Scholar
• MorseMAGarstJOsadaTA phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancerJ Transl Med200531915723705
   PubMed Web of Science ®Google Scholar
• EscudierBDorvalTChaputNVaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trialJ Transl Med2005311015740633
   PubMed Web of Science ®Google Scholar
• DaiSWeiDWuZPhase I clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancerMol Ther200816478279018362931
   PubMed Web of Science ®Google Scholar
• AndréFChaputNSchartzNEExosomes as potent cell-free peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cellsJ Immunol200417242126213614764678
   PubMed Web of Science ®Google Scholar
• SeguraEGuérinCHoggNAmigorenaSThéryCCD8+ dendritic cells use LFA-1 to capture MHC-peptide complexes from exosomes in vivoJ Immunol200717931489149617641014
   PubMed Web of Science ®Google Scholar
• ChaputNSchartzNEAndréFExosomes as potent cell-free peptide-based vaccine. II. Exosomes in CpG adjuvants efficiently prime naive Tc1 lymphocytes leading to tumor rejectionJ Immunol200417242137214614764679
   PubMed Web of Science ®Google Scholar
• GillietMFNestleFOGeneration of blood-derived human dendritic cells for antitumor immunotherapyMethods Mol Med20016429730321374269
   PubMedGoogle Scholar
• MarseeDKPinkusGSYuHCD71 (transferrin receptor): an effective marker for erythroid precursors in bone marrow biopsy specimensAm J Clin Pathol2010134342943520716799
   PubMed Web of Science ®Google Scholar
• SpeeckaertMMSpeeckaertRDelangheJRBiological and clinical aspects of soluble transferrin receptorCrit Rev Clin Lab Sci2010475–621322821391831
   PubMed Web of Science ®Google Scholar
• ThéryCDubanLSeguraEVéronPLantzOAmigorenaSIndirect activation of naïve CD4+ T cells by dendritic cell-derived exosomesNat Immunol20023121156116212426563
   PubMed Web of Science ®Google Scholar
• Sobo-VujanovicAMunichSVujanovicNLDendritic-cell exosomes cross-present Toll-like receptor-ligands and activate bystander dendritic cellsCell Immunol20142891–211912724759079
   PubMed Web of Science ®Google Scholar
• RaoQZuoBLuZTumor-derived exosomes elicit tumor suppression in murine hepatocellular carcinoma models and humans in vitroHepatology201664245647226990897
   PubMed Web of Science ®Google Scholar
• LuZZuoBJingRDendritic cell-derived exosomes elicit tumor regression in autochthonous hepatocellular carcinoma mouse modelsJ Hepatol201767473974828549917
   PubMed Web of Science ®Google Scholar