72
Views
16
CrossRef citations to date
0
Altmetric
Review

Predictive biomarkers for tumor immune checkpoint blockade

, , , , , & show all
Pages 4501-4507 | Published online: 11 Oct 2018

References

  • SiegelRLMillerKDJemalACancer Statistics, 2017CA Cancer J Clin201767173028055103
  • HowladerNNooneAMKrapchoMSEER Cancer Statistics Review, 1975–2013Bethesda, MDNational Cancer Institute2016 Available from: http://seer.cancer.gov/csr/1975_2013/
  • JaysonGCKerbelREllisLMHarrisALAntiangiogenic therapy in oncology: current status and future directionsLancet20163881004351852926853587
  • MahoneyKMRennertPDFreemanGJCombination cancer immunotherapy and new immunomodulatory targetsNat Rev Drug Discov201514856158426228759
  • AssiHIKamphorstAOMoukalledNMRamalingamSSImmune checkpoint inhibitors in advanced non-small cell lung cancerCancer2018124224826129211297
  • BoussiotisVAMolecular and Biochemical Aspects of the PD-1 Checkpoint PathwayN Engl J Med2016375181767177827806234
  • DongHZhuGTamadaKChenLB7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretionNat Med19995121365136910581077
  • LatchmanYWoodCRChernovaTPD-L2 is a second ligand for PD-1 and inhibits T cell activationNat Immunol20012326126811224527
  • KythreotouASiddiqueAMauriFABowerMPinatoDJPD-L1J Clin Pathol201871318919429097600
  • O’DaySJHamidOUrbaWJTargeting cytotoxic T-lymphocyte antigen-4 (CTLA-4): a novel strategy for the treatment of melanoma and other malignanciesCancer2007110122614262718000991
  • GaronEBRizviNAHuiRKEYNOTE-001 InvestigatorsPembrolizumab for the treatment of non-small-cell lung cancerN Engl J Med2015372212018202825891174
  • JacquelotNRobertiMPEnotDPPredictors of responses to immune checkpoint blockade in advanced melanomaNat Commun20178159228928380
  • BrahmerJReckampKLBaasPNivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung CancerN Engl J Med2015373212313526028407
  • RittmeyerABarlesiFWaterkampDOAK Study GroupAtezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trialLancet20173891006625526527979383
  • HellmannMDCallahanMKAwadMMTumor Mutational Burden and Efficacy of Nivolumab Monotherapy and in Combination with Ipilimumab in Small-Cell Lung CancerCancer Cell2018335853861.e429731394
  • HellmannMDCiuleanuTEPluzanskiANivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational BurdenN Engl J Med2018378222093210429658845
  • CarboneDPReckMPaz-AresLCheckMate 026 InvestigatorsFirst-Line Nivolumab in Stage IV or Recurrent Non-Small-Cell Lung CancerN Engl J Med2017376252415242628636851
  • SchattonTScolyerRAThompsonJFMihmMCJrTumor-infiltrating lymphocytes and their significance in melanoma prognosisMethods Mol Biol2014110228732424258985
  • WeissSAHanSWLuiKImmunologic heterogeneity of tumor-infiltrating lymphocyte composition in primary melanomaHum Pathol20165711612527473267
  • LeeNZakkaLRMihmMCSchattonTTumour-infiltrating lymphocytes in melanoma prognosis and cancer immunotherapyPathology201648217718727020390
  • KeirMEButteMJFreemanGJSharpeAHPD-1 and its ligands in tolerance and immunityAnnu Rev Immunol20082667770418173375
  • RitprajakPAzumaMIntrinsic and extrinsic control of expression of the immunoregulatory molecule PD-L1 in epithelial cells and squamous cell carcinomaOral Oncol201551322122825500094
  • AzumaKOtaKKawaharaAAssociation of PD-L1 overexpression with activating EGFR mutations in surgically resected nonsmall-cell lung cancerAnn Oncol201425101935194025009014
  • MarzecMZhangQGoradiaAOncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1)Proc Natl Acad Sci U S A200810552208522085719088198
  • MadoreJVilainREMenziesAMPD-L1 expression in melanoma shows marked heterogeneity within and between patients: implications for anti-PD-1/PD-L1 clinical trialsPigment Cell Melanoma Res201528324525325477049
  • CalleaMAlbigesLGuptaMDifferential Expression of PD-L1 between Primary and Metastatic Sites in Clear-Cell Renal Cell CarcinomaCancer Immunol Res20153101158116426014095
  • BorghaeiHPaz-AresLHornLNivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung CancerN Engl J Med2015373171627163926412456
  • McLaughlinJHanGSchalperKAQuantitative Assessment of the Heterogeneity of PD-L1 Expression in Non-Small-Cell Lung CancerJAMA Oncol201621465426562159
  • BalarAVCastellanoDO’DonnellPHFirst-line pembrolizumab in cisplatin-ineligible patients with locally advanced and unresectable or metastatic urothelial cancer (KEYNOTE-052): a multicentre, single-arm, phase 2 studyLancet Oncol201718111483149228967485
  • ChalmersZRConnellyCFFabrizioDAnalysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burdenGenome Med2017913428420421
  • LlosaNJCruiseMTamAThe vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpointsCancer Discov201551435125358689
  • LeDTDurhamJNSmithKNMismatch repair deficiency predicts response of solid tumors to PD-1 blockadeScience2017357634940941328596308
  • GainorJFShawATSequistLVEGFR Mutations and ALK Rearrangements Are Associated with Low Response Rates to PD-1 Pathway Blockade in Non-Small Cell Lung Cancer: A Retrospective AnalysisClin Cancer Res201622184585459327225694
  • HarataniKHayashiHTanakaTTumor immune microenvironment and nivolumab efficacy in EGFR mutation-positive non-small-cell lung cancer based on T790M status after disease progression during EGFR-TKI treatmentAnn Oncol20172871532153928407039
  • DongZYZhongWZZhangXCPotential Predictive Value of TP53 and KRAS Mutation Status for Response to PD-1 Blockade Immunotherapy in Lung AdenocarcinomaClin Cancer Res201723123012302428039262
  • IbrahimEMAl-FoheidiMEAl-MansourMMKazkazGAThe prognostic value of tumor-infiltrating lymphocytes in triple-negative breast cancer: a meta-analysisBreast Cancer Res Treat2014148346747625361613
  • WolfGTChepehaDBBellileETumor infiltrating lymphocytes (TIL) and prognosis in oral cavity squamous carcinoma: a preliminary studyOral Oncol2015511909525283344
  • LiBSeversonEPignonJCComprehensive analyses of tumor immunity: implications for cancer immunotherapyGenome Biol201617117427549193
  • McGranahanNFurnessAJRosenthalRClonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockadeScience201635162801463146926940869
  • ZhengCZhengLYooJKLandscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell SequencingCell2017169713421356.e1628622514
  • ZhangXZhangWYuanXFuMQianHXuWNeutrophils in cancer development and progression: Roles, mechanisms, and implications (Review)Int J Oncol201649385786727573431
  • RakicABeaudryPMahoneyDJThe complex interplay between neutrophils and cancerCell Tissue Res2018371351752929427051
  • LairdBJFallonMHjermstadMJQuality of Life in Patients With Advanced Cancer: Differential Association With Performance Status and Systemic Inflammatory ResponseJ Clin Oncol201634232769277527354484
  • LiSXuXLiangDTianGSongSHeYPrognostic value of blood neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in patients with gastric cancerZhonghua Zhong Liu Za Zhi2014361291091525623765
  • DiemSSchmidSKrapfMNeutrophil-to-Lymphocyte ratio (NLR) and Platelet-to-Lymphocyte ratio (PLR) as prognostic markers in patients with non-small cell lung cancer (NSCLC) treated with nivolumabLung Cancer201711117618128838390
  • MartensAWistuba-HamprechtKGeukes FoppenMBaseline Peripheral Blood Biomarkers Associated with Clinical Outcome of Advanced Melanoma Patients Treated with IpilimumabClin Cancer Res201622122908291826787752
  • WeideBMartensAHasselJCBaseline Biomarkers for Outcome of Melanoma Patients Treated with PembrolizumabClin Cancer Res201622225487549627185375
  • MlecnikBBindeaGAngellHKIntegrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite InstabilityImmunity201644369871126982367
  • CaseySCTongLLiYMYC regulates the antitumor immune response through CD47 and PD-L1Science2016352628222723126966191
  • PengWChenJQLiuCLoss of PTEN Promotes Resistance to T Cell-Mediated ImmunotherapyCancer Discov20166220221626645196
  • WooSRFuertesMBCorralesLSTING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumorsImmunity201441583084225517615
  • FuJKanneDBLeongMSTING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockadeSci Transl Med20157283283ra252
  • MickePOstmanATumourstroma interaction: cancer-associated fibroblasts as novel targets in anti-cancer therapy?Lung Cancer200445Suppl 2S163S17515552797
  • HeHQiLXiaoYHouYTumor Associated Fibroblasts Promote PD-L1 Expression in Lung Cancer CellsZhongguo Fei Ai Za Zhi201720529329728532535
  • WeberJSGibneyGSullivanRJSequential administration of nivolumab and ipilimumab with a planned switch in patients with advanced melanoma (CheckMate 064): an open-label, randomised, phase 2 trialLancet Oncol201617794395527269740