Advanced search
Publication Cover
Cancer Management and Research Volume 10, 2018 - Issue
Submit an article Journal homepage
67
Views
23
CrossRef citations to date
0
Altmetric
Original Research

12-HETE facilitates cell survival by activating the integrin-linked kinase/NF-κB pathway in ovarian cancer

Qian Liu1 Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China, [email protected]; [email protected]Correspondence[email protected] [email protected]
,
Wenhua Tan1 Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China, [email protected]; [email protected]
,
Jianhua Che1 Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China, [email protected]; [email protected]
,
Dandan Yuan1 Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China, [email protected]; [email protected]
,
Liying Zhang1 Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China, [email protected]; [email protected]
,
Yuhong Sun1 Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China, [email protected]; [email protected]
,
Xiaolong Yue2 Department of Medical Oncology, Affiliated Tumor Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China
,
Lei Xiao3 Department of General Surgery, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China
&
Yuxia Jin1 Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China, [email protected]; [email protected]Correspondence[email protected] [email protected]
 show all
Pages 5825-5838 | Published online: 16 Nov 2018

References

  • LandenCNBirrerMJSoodAKEarly events in the pathogenesis of epithelial ovarian cancerJ Clin Oncol2008266995100518195328
  • VergoteITropéCGAmantFEuropean Organization for Research and Treatment of Cancer-Gynaecological Cancer Group; NCIC Clinical Trials Group. Neoadjuvant chemotherapy or primary surgery in stage IIIC or IV ovarian cancerN Engl J Med201036394395320818904
  • HedströmEPederivaCFarneboJDownregulation of the cancer susceptibility protein WRAP53β in epithelial ovarian cancer leads to defective DNA repair and poor clinical outcomeCell Death Dis20156e189226426684
  • LiuJYYangJInceogluBInhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine modelBiochem Pharmacol201079688088719896470
  • HuYSunHO’FlahertyJTEdwardsIJ15-Lipoxygenase-1-mediated metabolism of docosahexaenoic acid is required for syndecan-1 signaling and apoptosis in prostate cancer cellsCarcinogenesis201334117618223066085
  • AraGTeicherBACyclooxygenase and lipoxygenase inhibitors in cancer therapyProstaglandins Leukot Essent Fatty Acids19965413168992490
  • JiangYPanYRheaPRA Sucrose-Enriched Diet Promotes Tumorigenesis in Mammary Gland in Part through the 12-Lipoxygenase PathwayCancer Res2016761242926729790
  • ChangJJiangLWangY12/15 Lipoxygenase regulation of colorectal tumorigenesis is determined by the relative tumor levels of its metabolite 12-HETE and 13-HODE in animal modelsOncotarget2015652879288825576922
  • DedharSWilliamsBHanniganGIntegrin-linked kinase (ILK): a regulator of integrin and growth-factor signallingTrends Cell Biol19999831932310407411
  • DedharSCell-substrate interactions and signaling through ILKCurr Opin Cell Biol200012225025610712922
  • HanKSLiNRavenPATargeting Integrin-Linked Kinase Suppresses Invasion and Metastasis through Downregulation of Epithelial-to-Mesenchymal Transition in Renal Cell CarcinomaMol Cancer Ther20151441024103425657336
  • ChoiYPKimBGGaoMQKangSChoNHTargeting ILK and β4 integrin abrogates the invasive potential of ovarian cancerBiochem Biophys Res Commun2012427364264823026047
  • LiQLiCZhangYYSilencing of integrin-linked kinase suppresses in vivo tumorigenesis of human ovarian carcinoma cellsMol Med Rep2013731050105423340803
  • LössnerDAbou-AjramCBengeAAumercierMSchmittMReuningUIntegrin alphavbeta3 upregulates integrin-linked kinase expression in human ovarian cancer cells via enhancement of ILK gene transcriptionJ Cell Physiol2009220236737519334037
  • LiuQXiaoLYuanDShiXLiPSilencing of the integrin-linked kinase gene induces the apoptosis in ovarian carcinomaJ Recept Signal Transduct Res201232212012722384810
  • AnnunziataCMStavnesHTKleinbergLNuclear factor kappaB transcription factors are coexpressed and convey a poor outcome in ovarian cancerCancer2010116133276328420564628
  • SinghaBGatlaHRMannaSProteasome inhibition increases recruitment of IκB kinase β (IKKβ), S536P-p65, and transcription factor EGR1 to interleukin-8 (IL-8) promoter, resulting in increased IL-8 production in ovarian cancer cellsJ Biol Chem201428952687270024337575
  • RyooHDBergmannAThe role of apoptosis-induced proliferation for regeneration and cancerCold Spring Harb Perspect Biol201248a00879722855725
  • YangPCartwrightCALiJArachidonic acid metabolism in human prostate cancerInt J Oncol20124141495150322895552
  • DaiDLMakretsovNCamposEIIncreased expression of integrin-linked kinase is correlated with melanoma progression and poor patient survivalClin Cancer Res20039124409441414555513
  • HanniganGTroussardAADedharSIntegrin-linked kinase: a cancer therapeutic target unique among its ILKNat Rev Cancer200551516315630415
  • AggarwalBBNuclear factor-kappaB: the enemy withinCancer Cell20046320320815380510
  • KwonHJChoiGERyuSStepwise phosphorylation of p65 promotes NF-κB activation and NK cell responses during target cell recognitionNat Commun201671168627221592
  • SakuraiHChibaHMiyoshiHSugitaTToriumiWIkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domainJ Biol Chem199927443303533035610521409
  • CohenLHenzelWJBaeuerlePAIKAP is a scaffold protein of the IkappaB kinase complexNature199839566992922969751059

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.