miR-424 targets AKT3 and PSAT1 and has a tumor-suppressive role in human colorectal cancer

Yifeng Fang1 Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China, [email protected]

Xiao Liang1 Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China, [email protected]

Junfen Xu2 Department of Gynecologic Oncology, Women’s Hospital, Zhejiang University School of Medicine, Hangzhou, China, [email protected]Correspondence[email protected]

Xiujun Cai1 Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China, [email protected]Correspondence[email protected]

Pages 6537-6547 | Published online: 29 Nov 2018

Cite this article
CrossMark

Full Article
Figures & data
References
Citations
Metrics
Licensing
Reprints & Permissions
View PDF PDF

References

TorreLABrayFSiegelRLFerlayJLortet-TieulentJJemalAGlobal cancer statistics, 2012CA Cancer J Clin2015652 8710825651787
PubMed Web of Science ®Google Scholar
CenterMMJemalASmithRAWardEWorldwide variations in colorectal cancerCA Cancer J Clin2009596 36637819897840
PubMed Web of Science ®Google Scholar
DesantisCELinCCMariottoABCancer treatment and survivorship statistics, 2014CA Cancer J Clin2014644 25227124890451
PubMed Web of Science ®Google Scholar
BartelDPMicroRNAs: target recognition and regulatory functionsCell20091362 21523319167326
PubMed Web of Science ®Google Scholar
IorioMVCroceCMMicroRNA involvement in human cancerCarcinogenesis2012336 1126113322491715
PubMed Web of Science ®Google Scholar
PasquinelliAEMicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationshipNat Rev Genet2012134 27128222411466
PubMed Web of Science ®Google Scholar
LinSGregoryRIMicroRNA biogenesis pathways in cancerNat Rev Cancer2015156 32133325998712
PubMed Web of Science ®Google Scholar
SayedDAbdellatifMMicroRNAs in development and diseasePhysiol Rev2011913 82788721742789
PubMed Web of Science ®Google Scholar
XuJFangYWangXCUL2 overexpression driven by CUL2/E2F1/miR-424 regulatory loop promotes HPV16 E7 induced cervical carcinogenesisOncotarget2016721 315203153327153550
PubMedGoogle Scholar
FangYYuHLiangXXuJCaiXChk1-induced CCNB1 overexpression promotes cell proliferation and tumor growth in human colorectal cancerCancer Biol Ther2014159 1268127924971465
PubMed Web of Science ®Google Scholar
XuJWanXChenXmiR-2861 acts as a tumor suppressor via targeting EGFR/AKT2/CCND1 pathway in cervical cancer induced by human papillomavirus virus 16 E6Sci Rep201662896827364926
PubMed Web of Science ®Google Scholar
YangHZhengWShuaiXMicroRNA-424 inhibits Akt3/E2F3 axis and tumor growth in hepatocellular carcinomaOncotarget2015629 277362775026315541
PubMedGoogle Scholar
FinnertyJRWangWXHébertSSWilfredBRMaoGNelsonPTThe miR-15/107 group of microRNA genes: evolutionary biology, cellular functions, and roles in human diseasesJ Mol Biol20104023 49150920678503
PubMed Web of Science ®Google Scholar
LeeAPapangeliIParkYA PPARγ-dependent miR-424/503-CD40 axis regulates inflammation mediated angiogenesisSci Rep201771 252828566713
PubMedGoogle Scholar
ZhangDShiZLiMMiJHypoxia-induced miR-424 decreases tumor sensitivity to chemotherapy by inhibiting apoptosisCell Death Dis20145e130124967963
PubMed Web of Science ®Google Scholar
PengHYJiangSSHsiaoJRIL-8 induces miR-424-5p expression and modulates SOCS2/STAT5 signaling pathway in oral squamous cell carcinomaMol Oncol2016106 89590927038552
PubMed Web of Science ®Google Scholar
DrasinDJGuarnieriALNeelakantanDTWIST1-induced miR-424 reversibly drives mesenchymal programming while inhibiting tumor initiationCancer Res2015759 1908192125716682
PubMed Web of Science ®Google Scholar
XuJLiYWangFSuppressed miR-424 expression via upregulation of target gene Chk1 contributes to the progression of cervical cancerOncogene2013328 97698722469983
PubMed Web of Science ®Google Scholar
Rodriguez-BarruecoRNekritzEABertucciFmiR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapyGenes Dev2017316 55356628404630
PubMed Web of Science ®Google Scholar
ChenBDuanLYinGTanJJiangXSimultaneously expressed miR-424 and miR-381 synergistically suppress the proliferation and survival of renal cancer cells–Cdc2 activity is up-regulated by targeting WEE1Clinics (Sao Paulo)2013686 82583323778472
PubMed Web of Science ®Google Scholar
YuLDingGFHeCSunLJiangYZhuLMicroRNA-424 is down-regulated in hepatocellular carcinoma and suppresses cell migration and invasion through c-MybPLoS One201493 e9166124675898
PubMed Web of Science ®Google Scholar
WeiSLiQLiZWangLZhangLXuZmiR-424-5p promotes proliferation of gastric cancer by targeting Smad3 through TGF-β signaling pathwayOncotarget2016746 751857519627655675
PubMedGoogle Scholar
LimLPLauNCGarrett-EngelePMicroarray analysis shows that some microRNAs downregulate large numbers of target mRNAsNature20054337027 76977315685193
PubMed Web of Science ®Google Scholar
LewisBPShihIHJones-RhoadesMWBartelDPBurgeCBPrediction of mammalian microRNA targetsCell20031157 78779814697198
PubMed Web of Science ®Google Scholar
BartelDPChenCZMicromanagers of gene expression: the potentially widespread influence of metazoan microRNAsNat Rev Genet200455 39640015143321
PubMed Web of Science ®Google Scholar
GonzalezEMcGrawTEThe Akt kinases: isoform specificity in metabolism and cancerCell Cycle2009816 2502250819597332
PubMed Web of Science ®Google Scholar
StålOPérez-TenorioGAkerbergLAkt kinases in breast cancer and the results of adjuvant therapyBreast Cancer Res200352 R374412631397
PubMed Web of Science ®Google Scholar
RoyHKOlusolaBFClemensDLAKT proto-oncogene overexpression is an early event during sporadic colon carcinogenesisCarcinogenesis2002231 20120511756242
PubMed Web of Science ®Google Scholar
StahlJMSharmaACheungMDeregulated Akt3 activity promotes development of malignant melanomaCancer Res20046419 7002701015466193
PubMed Web of Science ®Google Scholar
ViéNCopoisVBascoul-MolleviCOverexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cellsMol Cancer200871418221502
PubMed Web of Science ®Google Scholar

Share icon
Back to Top

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.

People also read
Recommended articles
Cited by

To cite this article:

Reference style: APA Chicago Harvard

Citation copied to clipboard

Reference styles above use APA (6th edition), Chicago (16th edition) & Harvard (10th edition)

Download citation

Download a citation file in RIS format that can be imported by citation management software including EndNote, ProCite, RefWorks and Reference Manager.

Choose format: RIS BibTex RefWorks Direct Export

Choose options: Citation Citation & abstract Citation & references

miR-424 targets AKT3 and PSAT1 and has a tumor-suppressive role in human colorectal cancer

References

Information for

Open access

Opportunities

Help and information

Your download is now in progress and you may close this window

Login or register to access this feature

miR-424 targets AKT3 and PSAT1 and has a tumor-suppressive role in human colorectal cancer

References

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date