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Cancer Management and Research Volume 11, 2019 - Issue
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Original Research

IRF1 inhibits the proliferation and metastasis of colorectal cancer by suppressing the RAS-RAC1 pathway

Min Hong1 Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China, [email protected];2 Department of Pathology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China
,
Zuoyang Zhang3 Department of Pathology, School of Basic Medical Sciences, Anhui Medical University, Hefei, China
,
Qing Chen4 Department of Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China
,
Yanxia Lu1 Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China, [email protected]
,
Jianming Zhang1 Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China, [email protected];4 Department of Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China
,
Chun Lin1 Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China, [email protected]
,
Fan Zhang1 Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China, [email protected]
,
Wenjuan Zhang1 Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China, [email protected]
,
Xiaomin Li1 Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China, [email protected]
,
Wei Zhang1 Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China, [email protected]
&
Xuenong Li1 Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China, [email protected]Correspondence[email protected]
 show all
Pages 369-378 | Published online: 31 Dec 2018

References

  • NivYMucin and colorectal cancer metastasisAm J Gastroenterol19948956656698172135
  • TorreLABrayFSiegelRLFerlayJLortet-TieulentJJemalAGlobal cancer statistics, 2012CA Cancer J Clin20156528710825651787
  • KomatsuYDerwishLHirasawaKIRF1 Downregulation by Ras/MEK Is independent of translational control of IRF1 mRNAPLoS One2016118e016052927508303
  • Mirjačić MartinovićKSrdić-RajićTBabovićNDžodićRJurišićVKonjevićGDecreased expression of pSTAT, IRF-1 and DAP10 signalling molecules in peripheral blood lymphocytes of patients with metastatic melanomaJ Clin Pathol201669430030626442832
  • SzelagMPiaszyk-BorychowskaAPlens-GalaskaMWesolyJBluyssenHATargeted inhibition of STATs and IRFs as a potential treatment strategy in cardiovascular diseaseOncotarget2016730487884881227166190
  • ZhanFBLiuHLaiRFJakovlićIWangWBWangWMMolecular identification and functional characterisation of the interferon regulatory factor 1 in the blunt snout bream (Megalobrama amblycephala)Fish Shellfish Immunol20165445646527150048
  • ShahSKingEMMostafaMMAltonsyMONewtonRDUSP1 maintains IRF1 and leads to increased expression of IRF1-dependent genes: a mechanism promoting glucocorticoid insensitivityJ Biol Chem201629141218022181627551049
  • LimRTranHTLiongSBarkerGLappasMThe transcription factor interferon regulatory factor-1 (IRF1) plays a key role in the terminal effector pathways of human preterm laborBiol Reprod20169423226674566
  • LeslieACareyFAPrattNRSteeleRJThe colorectal adenoma-carcinoma sequenceBr J Surg200289784586012081733
  • LiaoTJTsaiCJJangHFushmanDNussinovRRASSF5: An MST activator and tumor suppressor in vivo but opposite in vitroCurr Opin Struct Biol20164121722427643882
  • DammannRYangGPfeiferGPHypermethylation of the cpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancersCancer Res20016173105310911306494
  • DonningerHSchmidtMLMezzanotteJBarnoudTClarkGJRas signaling through RASSF proteinsSemin Cell Dev Biol201658869527288568
  • Walch-RückheimBPahne-ZeppenfeldJFischbachJSTAT3/IRF1 pathway activation sensitizes cervical cancer cells to chemotherapeutic drugsCancer Res201676133872388327216197
  • PlaisierCLO’BrienSBernardBCausal mechanistic regulatory network for glioblastoma deciphered using systems genetics network analysisCell Syst20163217218627426982
  • XieCLiuCWuBEffects of IRF1 and IFN-β interaction on the M1 polarization of macrophages and its antitumor functionInt J Mol Med201638114816027176664
  • ZhangZYLuYXZhangZYLoss of TINCR expression promotes proliferation, metastasis through activating EpCAM cleavage in colorectal cancerOncotarget2016716226392264927009809
  • YuanLZhouCLuYIFN-γ-mediated IRF1/miR-29b feedback loop suppresses colorectal cancer cell growth and metastasis by repressing IGF1Cancer Lett2015359113614725592039
  • ShanSQiCZhuYLiHAnLYangGExpression profile of carp IFN correlate with the up-regulation of interferon regulatory factor-1 (IRF-1) in vivo and in vitro: the pivotal molecules in antiviral defenseFish Shellfish Immunol2016529410226993613
  • PavanSOliveroMCoràDdi RenzoMFIRF-1 expression is induced by cisplatin in ovarian cancer cells and limits drug effectivenessEur J Cancer201349496497323079474
  • LorenziSForloniMCifaldiLIRF1 and NF-kB restore MHC class I-restricted tumor antigen processing and presentation to cytotoxic T cells in aggressive neuroblastomaPLoS One2012710e4692823071666
  • ChenCJLinTTShivelyJERole of interferon regulatory factor-1 in the induction of biliary glycoprotein (cell CAM-1) by interferon-gammaJ Biol Chem19962714528181281888910434
  • LiuXRuJZhangJmiR-23a targets interferon regulatory factor 1 and modulates cellular proliferation and paclitaxel-induced apoptosis in gastric adenocarcinoma cellsPLoS One201386e6470723785404
  • XuLZhouXWangWIFN regulatory factor 1 restricts hepatitis E virus replication by activating STAT1 to induce antiviral IFN-stimulated genesFASEB J201630103352336727328944
  • WaltersKAOlsufkaRKuestnerREPrior infection with type A Francisella tularensis antagonizes the pulmonary transcriptional response to an aerosolized Toll-like receptor 4 agonistBMC Genomics20151687426510639
  • LanYTJen-KouLLinCHMutations in the RAS and PI3K pathways are associated with metastatic location in colorectal cancersJ Surg Oncol2015111790591025920435
  • AlamoPGallardoAdi NicolantonioFHigher metastatic efficiency of KRas G12V than KRas G13D in a colorectal cancer modelFASEB J201529246447625359494

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