References
- JainRKNormalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapyNat Med20017998798911533692
- JainRKDudaDGClarkJWLoefflerJSLessons from phase III clinical trials on anti-VEGF therapy for cancerNat Clin Pract Oncol200631244016407877
- TongRTBoucherYKozinSVWinklerFHicklinDJJainRKVascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumorsCancer Res200464113731373615172975
- IzumiYXuLdi TomasoEFukumuraDJainRKTumour biology: Herceptin acts as an anti-angiogenic cocktailNature20024166878279280
- AnsiauxRBaudeletCJordanBFMechanism of reoxygenation after antiangiogenic therapy using SU5416 and its importance for guiding combined antitumor therapyCancer Res200666199698970417018628
- AnsiauxRBaudeletCJordanBFThalidomide radiosensitizes tumors through early changes in the tumor microenvironmentClin Cancer Res2005112 Pt 174375015701864
- DingsRPLorenMHeunHScheduling of radiation with angiogenesis inhibitors anginex and Avastin improves therapeutic outcome via vessel normalizationClin Cancer Res200713113395340217545548
- BatchelorTTSorensenAGdi TomasoEAZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vascu-lature and alleviates edema in glioblastoma patientsCancer Cell2007111839517222792
- GuQHuCChenQXiaYFengJYangH[Prevention of chinese green tea on 3,4-benzopyrene-induced lung cancer and its mechanism in animal mode]Zhongguo Fei Ai Za Zhi2008114519523 Chinese20735961
- LiJJGuQHLiMYangHPCaoLMHuCPRole of Ku70 and Bax in epigallocatechin-3-gallate-induced apoptosis of A549 cells in vivoOncol Lett20135110110623255902
- MaYCLiCGaoFEpigallocatechin gallate inhibits the growth of human lung cancer by directly targeting the EGFR signaling pathwayOncol Rep20143131343134924366444
- SongXDuJZhaoWGuoZEpigallocatechin-3-gallate (EGCG): mechanisms and the combined applicationsComb Chem High Throughput Screen Epub20171217
- JungYDKimMSShinBAEGCG, a major component of green tea, inhibits tumour growth by inhibiting VEGF induction in human colon carcinoma cellsBr J Cancer200184684485011259102
- ShimizuMShirakamiYSakaiH(-)-Epigallocatechin gallate inhibits growth and activation of the VEGF/VEGFR axis in human colorectal cancer cellsChem Biol Interact2010185324725220346928
- RashidiBMalekzadehMGoodarziMMasoudifarAMirzaeiHGreen tea and its anti-angiogenesis effectsBiomed Pharmacother20178994995628292023
- ShapiroRValleeBLSite-directed mutagenesis of histidine-13 and histidine-114 of human angiogenin. alanine derivatives inhibit angiogenin-induced angiogenesisBiochemistry19892818740174082479414
- DengPBHuCPXiongZYangHPLiYYTreatment with EGCG in NSCLC leads to decreasing interstitial fluid pressure and hypoxia to improve chemotherapy efficacy through rebalance of Ang-1 and Ang-2Chin J Nat Med201311324525323725836
- LiuXLPengCWChenCQuantum dots-based double-color imaging of HER2 positive breast cancer invasionBiochem Biophys Res Commun2011409357758221609713
- MyersALWilliamsRFNgCYHartwichJEDavidoffAMBev-acizumab-induced tumor vessel remodeling in rhabdomyosarcoma xenografts increases the effectiveness of adjuvant ionizing radiationJ Pediatr Surg20104561080108520620299
- EberhardAKahlertSGoedeVHemmerleinBPlateKHAugustinHGHeterogeneity of angiogenesis and blood vessel maturation in human tumors: implications for antiangiogenic tumor therapiesCancer Res20006051388139310728704
- RolnyCMazzoneMTuguesSHRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PLGFCancer Cell2011191314421215706
- DicksonPVHamnerJBSimsTLBevacizumab-induced transient remodeling of the vasculature in neuroblastoma xenografts results in improved delivery and efficacy of systemically administered chemotherapyClin Cancer Res200713133942395017606728
- FukumuraDJainRKTumor microvasculature and microenvironment: targets for anti-angiogenesis and normalizationMicrovasc Res2007742–3728417560615
- BoucherYKirkwoodJMOpacicDDesantisMJainRKInterstitial hypertension in superficial metastatic melanomas in humansCancer Res19915124669166941742743
- RaleighJAChouSCArteelGEHorsmanMRComparisons among pimonidazole binding, oxygen electrode measurements, and radiation response in C3H mouse tumorsRadiat Res1999151558058910319731
- WeidnerNIntratumor microvessel density as a prognostic factor in cancerAm J Pathol199514719197541613
- DoupleEBTottenMDSpencerFPlatinum levels in murine tumor following intraperitoneal administration of cisplatin or paraplatinNCI Monogr19886129132
- JiangZPoreNCernigliaGJPhosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolo-mide that is reversed by the protease inhibitor nelfinavirCancer Res20076794467447317483362
- DebbagePLGriebelJRiedMGneitingTDevriesAHutzlerPLectin intravital perfusion studies in tumor-bearing mice: micrometer-resolution, wide-area mapping of microvascular labeling, distinguishing efficiently and inefficiently perfused microregions in the tumorJ Histochem Cytochem19984656276399562571
- FalcónBLHashizumeHKoumoutsakosPContrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vesselsAm J Pathol200917552159217019815705
- SchnellCRStaufferFAllegriniPREffects of the dual phospha-tidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 on the tumor vasculature: implications for clinical imagingCancer Res200868166598660718701483
- JainRKMolecular regulation of vessel maturationNat Med20039668569312778167
- SakamotoYTerashitaNMuraguchiTFukusatoTKubotaSEffects of epigallocatechin-3-gallate (EGCG) on A549 lung cancer tumor growth and angiogenesisBiosci Biotechnol Biochem20137791799180324018658
- ShiJLiuFZhangWLiuXLinBTangXEpigallocatechin-3-gallate inhibits nicotine-induced migration and invasion by the suppression of angiogenesis and epithelial-mesenchymal transition in non-small cell lung cancer cellsOncol Rep20153362972298025845434
- WangJManGCWChanTHKwongJWangCCA prodrug of green tea polyphenol (-)-epigallocatechin-3-gallate (Pro-EGCG) serves as a novel angiogenesis inhibitor in endometrial cancerCancer Lett2018412102029024813
- ShankarSChenQSrivastavaRKInhibition of PI3K/Akt and MEK/ERK pathways act synergistically to enhance antiangiogenic effects of EGCG through activation of FoxO transcription factorJ Mol Signal20083718355401
- LatkerCHKuwabaraTRegression of the tunica vasculosa lentis in the postnatal ratInvest Ophthalmol Vis Sci19812156896997298273
- VrackoRBasal lamina scaffold-anatomy and significance for maintenance of orderly tissue structureAm J Pathol19747723143464614671
- ShankarSGanapathySHingoraniSRSrivastavaRKEGCG inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancerFront Biosci20081344045217981559
- NakamutaMHigashiNKohjimaMEpigallocatechin-3-gallate, a polyphenol component of green tea, suppresses both collagen production and collagenase activity in hepatic stellate cellsInt J Mol Med200516467768116142404
- LessJRSkalakTCSevickEMJainRKMicrovascular architecture in a mammary carcinoma: branching patterns and vessel dimensionsCancer Res19915112652731988088
- JainRKNormalization of tumor vasculature: an emerging concept in antiangiogenic therapyScience20053075706586215637262
- BaishJWStylianopoulosTLanningRMScaling rules for diffusive drug delivery in tumor and normal tissuesProc Natl Acad Sci USA201110851799180321224417
- BoucherYJainRKMicrovascular pressure is the principal driving force for interstitial hypertension in solid tumors: implications for vascular collapseCancer Res19925218511051141516068
- YoungJSLumsdenCEStalkerALThe significance of the tissue pressure of normal testicular and of neoplastic (Brown-Pearce carcinoma) tissue in the rabbitJ Pathol Bacteriol195062331333314784896
- RofstadEKTunheimSHMathiesenBPulmonary and lymph node metastasis is associated with primary tumor interstitial fluid pressure in human melanoma xenograftsCancer Res200262366166411830516
- AirleyREPhillipsRMEvansAEHypoxia-regulated glucose transporter GLUT-1 may influence chemosensitivity to some alkylating agents: results of EORTC (first translational Award) study of the relevance of tumour hypoxia to the outcome of chemotherapy in human tumour-derived xenograftsInt J Oncol20052661477148415870859
- GreijerAEde JongMCSchefferGLShvartsAvan DiestPJvan der WallEHypoxia-induced acidification causes mitoxantrone resistance not mediated by drug transporters in human breast cancer cellsCell Oncol2005271434915750206
- JainRKAntiangiogenesis strategies revisited: from starving tumors to alleviating hypoxiaCancer Cell201426560562225517747
- MancusoMRDavisRNorbergSMRapid vascular regrowth in tumors after reversal of VEGF inhibitionJ Clin Invest2006116102610262117016557
- TeicherBADupuisNPRobinsonMFEmiYGoffDAAntiangio-genic treatment (TNP-470/minocycline) increases tissue levels of anticancer drugs in mice bearing Lewis lung carcinomaOncol Res1995752372438534929
- TeicherBAA systems approach to cancer therapy. (Antioncogenics + standard cytotoxics-->mechanism(s) of interaction)Cancer Metastasis Rev19961522472728842498
- MillerKWangMGralowJPaclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancerN Engl J Med2007357262666267618160686
- ReckMvon PawelJZatloukalPPhase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAilJ Clin Oncol20092781227123419188680
- ShimizuMAdachiSMasudaMKozawaOMoriwakiHCancer chemoprevention with green tea catechins by targeting receptor tyrosine kinasesMol Nutr Food Res201155683284321538846
- KhanNMukhtarHMultitargeted therapy of cancer by green tea polyphenolsCancer Lett2008269226928018501505
- DouQPMolecular mechanisms of green tea polyphenolsNutr Cancer200961682783520155623
- SinghTKatiyarSKGreen tea catechins reduce invasive potential of human melanoma cells by targeting COX-2, PGE2 receptors and epithelial-to-mesenchymal transitionPLoS One2011610e2522422022384