JAM3 functions as a novel tumor suppressor and is inactivated by DNA methylation in colorectal cancer

References

• SiegelRDesantisCJemalAColorectal Cancer statistics, 2014CA Cancer J Clin201464210411724639052
   PubMed Web of Science ®Google Scholar
• IrrazábalTBelchevaAGirardinSEMartinAPhilpottDJThe multifaceted role of the intestinal microbiota in colon cancerMol Cell201454230932024766895
   PubMed Web of Science ®Google Scholar
• LaoVVGradyWMEpigenetics and colorectal cancerNat Rev Gas-troenterol Hepatol2011812686700
   PubMed Web of Science ®Google Scholar
• DiazLABardelliALiquid biopsies: genotyping circulating tumor DNAJ Clin Oncol201432657958624449238
   PubMed Web of Science ®Google Scholar
• KulisMEstellerMDNA methylation and cancerAdv Genet201070275620920744
   PubMed Web of Science ®Google Scholar
• HanFLiuWJiangXSOX30, a novel epigenetic silenced tumor suppressor, promotes tumor cell apoptosis by transcriptional activating p53 in lung cancerOncogene201534334391440225435374
   PubMed Web of Science ®Google Scholar
• ZhouDTangWSuGPCDH18 is frequently inactivated by promoter methylation in colorectal cancerSci Rep201771281928588296
   PubMedGoogle Scholar
• BeckSRakyanVKThe methylome: approaches for global DNA methylation profilingTrends Genet200824523123718325624
   PubMed Web of Science ®Google Scholar
• SchoenbornJRDorschnerMOSekimataMComprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-gammaNat Immunol20078773274217546033
   PubMed Web of Science ®Google Scholar
• DejanaEEndothelial cell-cell junctions: happy togetherNat Rev Mol Cell Biol20045426127015071551
   PubMed Web of Science ®Google Scholar
• WolburgHNoellSMackAWolburg-BuchholzKFallier-BeckerPBrain endothelial cells and the glio-vascular complexCell Tissue Res20093351759618633647
   PubMed Web of Science ®Google Scholar
• EbnetKSuzukiAOhnoSVestweberDJunctional adhesion molecules (JAMs): more molecules with dual functions?J Cell Sci2004117Pt 1192914657270
   PubMed Web of Science ®Google Scholar
• ArrateMPRodriguezJMTranTMBrockTACunninghamSACloning of human junctional adhesion molecule 3 (JAM3) and its identification as the JAM2 counter-receptorJ Biol Chem200127649458264583211590146
   PubMed Web of Science ®Google Scholar
• BradfieldPFScheiermannCNoursharghSJAM-C regulates unidirectional monocyte transendothelial migration in inflammationBlood200711072545255517625065
   PubMed Web of Science ®Google Scholar
• KolaczkowskaEKubesPNeutrophil recruitment and function in health and inflammationNat Rev Immunol201313315917523435331
   PubMed Web of Science ®Google Scholar
• MandicourtGIdenSEbnetKAurrand-LionsMImhofBAJAM-C regulates tight junctions and integrin-mediated cell adhesion and migrationJ Biol Chem200728231830183717099249
   PubMed Web of Science ®Google Scholar
• HajjariMBehmaneshMSadeghizadehMZeinoddiniMJunctional adhesion molecules 2 and 3 may potentially be involved in progression of gastric adenocarcinoma tumorsMed Oncol201330138023277282
   PubMed Web of Science ®Google Scholar
• ZenKBabbinBALiuYJAM-C is a component of desmosomes and a ligand for CD11b/CD18-mediated neutrophil transepithelial migrationMol Biol Cell20041583926393715194813
   PubMed Web of Science ®Google Scholar
• HinoueTWeisenbergerDJLangeCPGenome-scale analysis of aberrant DNA methylation in colorectal cancerGenome Res201222227128221659424
   PubMed Web of Science ®Google Scholar
• AnHXNiederacherDBeckmannMWERBB2 gene amplification detected by fluorescent differential polymerase chain reaction in paraffin-embedded breast carcinoma tissuesInt J Cancer19956452912977591299
   PubMed Web of Science ®Google Scholar
• LuLKatsarosDde La LongraisIASochircaOYuHHypermeth-ylation of let-7a-3 in epithelial ovarian cancer is associated with low insulin-like growth factor-II expression and favorable prognosisCancer Res20076721101171012217974952
   PubMed Web of Science ®Google Scholar
• TanSSunCWeiXQuantitative assessment of lung cancer associated with genes methylation in the peripheral bloodExp Lung Res2013394–518219023614702
   PubMed Web of Science ®Google Scholar
• ShannonPMarkielAOzierOCytoscape: a software environment for integrated models of biomolecular interaction networksGenome Res200313112498250414597658
   PubMed Web of Science ®Google Scholar
• Martìn-PaduraILostaglioSSchneemannMJunctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigrationJ Cell Biol199814211171279660867
   PubMed Web of Science ®Google Scholar
• EbnetKAurrand-LionsMKuhnAThe junctional adhesion molecule (JAM) family members JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarityJ Cell Sci2003116Pt 193879389112953056
   PubMed Web of Science ®Google Scholar
• YinAZhangQKongXJAM3 methylation status as a biomarker for diagnosis of preneoplastic and neoplastic lesions of the cervixOncotarget2015642443734438726517242
   PubMed Web of Science ®Google Scholar
• SantosoSOrlovaVVSongKThe homophilic binding of junctional adhesion molecule-C mediates tumor cell-endothelial cell interactionsJ Biol Chem200528043363263633316118203
   PubMed Web of Science ®Google Scholar
• LiXYinAZhangWJAM3 promotes migration and suppresses apoptosis of renal carcinoma cell linesInt J Mol Med20184252923292930226554
   PubMed Web of Science ®Google Scholar
• ThieryJPEpithelial-mesenchymal transitions in tumour progressionNat Rev Cancer20022644245412189386
   PubMed Web of Science ®Google Scholar
• ZeisbergMNeilsonEGBiomarkers for epithelial-mesenchymal transitionsJ Clin Invest200911961429143719487819
   PubMed Web of Science ®Google Scholar
• De WeverOPauwelsPDe CraeneBMolecular and pathological signatures of epithelial-mesenchymal transitions at the cancer invasion frontHistochem Cell Biol2008130348149418648847
   PubMed Web of Science ®Google Scholar
• JeanesAGottardiCJYapASCadherins and cancer: how does cadherin dysfunction promote tumor progression?Oncogene200827556920692919029934
   PubMed Web of Science ®Google Scholar
• TianYTianYZhangWJunctional adhesion molecule-A, an epithelial-mesenchymal transition inducer, correlates with metastasis and poor prognosis in human nasopharyngeal cancerCarcinogenesis2015361414825416560
   PubMed Web of Science ®Google Scholar
• FangDHawkeDZhengYPhosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activityJ Biol Chem200728215112211122917287208
   PubMed Web of Science ®Google Scholar
• HeXCYinTGrindleyJCPTEN-deficient intestinal stem cells initiate intestinal polyposisNat Genet200739218919817237784
   PubMed Web of Science ®Google Scholar
• ChungCHBernardPSPerouCMMolecular portraits and the family tree of cancerNat Genet200232Suppl53354012454650
   PubMedGoogle Scholar