Multiphoton microscopy in the diagnostic assessment of pediatric solid tissue in comparison to conventional histopathology: results of the first international online interobserver trial

References

• Coffin CM, Spilker K, Zhou H, et al. Frozen section diagnosis in pediatric surgical pathology: a decade’s experience in a children’s hospital. Arch Pathol Lab Med. 2005;129:1619–1625. 16329734
   PubMed Web of Science ®Google Scholar
• Carrasco A Jr, Caldwell BT, Cost CR, et al. Reliability of intraoperative frozen section for the diagnosis of renal tumors suspicious for malignancy in children and adolescents. Pediatr Blood Cancer. 2017;64(8):e26458. doi:10.1002/pbc.v64.8
   Web of Science ®Google Scholar
• Dall’igna P, d’Amore ES, Cecchetto G, et al. Intraoperative examination (IOE) in pediatric extracranial tumors. Pediatr Blood Cancer. 2010;54:388–393. doi:10.1002/pbc.2230920052774
   PubMed Web of Science ®Google Scholar
• Jain M, Robinson BD, Wu B, Khani F, Mukherjee S. Exploring multiphoton microscopy as a novel tool to differentiate chromophobe renal cell carcinoma from oncocytoma in fixed tissue sections. Arch Pathol Lab Med. 2018;142(3):383–390. doi:10.5858/arpa.2017-0056-OA29219617
   PubMed Web of Science ®Google Scholar
• Jain M, Robinson BD, Aggarwal A, Shevchuk MM, Scherr DS, Mukherjee S. Multiphoton microscopy for rapid histopathological evaluation of kidney tumours. BJU Int. 2016;118(1):118–126. doi:10.1111/bju.1337726575175
   PubMed Web of Science ®Google Scholar
• Jain M, Robinson BD, Shevchuk MM, et al. Multiphoton microscopy: a potential intraoperative tool for the detection of carcinoma in situ in human bladder. Arch Pathol Lab Med. 2015;139(6):796–804. doi:10.5858/arpa.2014-0076-OA26030249
   PubMed Web of Science ®Google Scholar
• Jain M, Narula N, Aggarwal A, et al. Multiphoton microscopy: a potential “optical biopsy” tool for real-time evaluation of lung tumors without the need for exogenous contrast agents. Arch Pathol Lab Med. 2014;138(8):1037–1047. doi:10.5858/arpa.2013-0122-OA24199831
   PubMed Web of Science ®Google Scholar
• Durand M, Jain M, Aggarwal A, et al. Real-time in vivo periprostatic nerve tracking using multiphoton microscopy in a rat survival surgery model: a promising pre-clinical study for enhanced nerve-sparing surgery. BJU Int. 2015;116(3):478–486. doi:10.1111/bju.1290325124551
   PubMed Web of Science ®Google Scholar
• Liu G, Kieu IK, Wise FW, Chen Z. Multiphoton microscopy system with a compact fiber-based femtosecond-pulse laser and handheld probe. J Biophot. 2011;4:34–39. doi:10.1002/jbio.201000049
   PubMed Web of Science ®Google Scholar
• Helmchen F, Denk W, Kerr JN. Miniaturization of two-photon microscopy for imaging in freely moving animals. Cold Spring Harb Protoc. 2013;10:904–913.
   Google Scholar
• Duan X, Li H, Qiu Z, et al. MEMS-based multiphoton endomicroscope for repetitive imaging of mouse colon. Biomed Opt Express. 2015;6(8):3074–3083. doi:10.1364/BOE.6.00307426309768
   PubMed Web of Science ®Google Scholar
• Muensterer OM, Waldron S, Boo YJ, et al. Multiphoton microscopy: a novel diagnostic method for solid tumors in a prospective pediatric oncologic cohort, an experimental study. Int J Surg. 2017;48:128–133. doi:10.1016/j.ijsu.2017.10.03829081372
   PubMed Web of Science ®Google Scholar
• Cohen JF, Korevaar DA, Altman DG, et al. STARD 2015 guidelines for reporting diagnostic accuracy studies: explanation and elaboration. BMJ Open. 2016;6(11):e012799. doi:10.1136/bmjopen-2016-012799
   PubMed Web of Science ®Google Scholar
• Bossuyt PM, Reitsma JB, Bruns DE, et al. STARD 2015: an updated list of essential items for reporting diagnostic accuracy studies. BMJ. 2015;351:h5527. doi:10.1136/bmj.h643226511519
   PubMed Web of Science ®Google Scholar
• Randolph JJ. Free-marginal multirater kappa (multirater K[free]): an alternative to fleiss’ fixed-marginal multirater kappa. Online Submiss; 2005 Available from: http://eric.ed.gov/?id=ED490661 (Availability checked on November 26, 2018).
   Google Scholar
• Yan J, Zheng Y, Zheng X, et al. Real-time optical diagnosis of gastric cancer with serosal invasion using multiphoton imaging. Sci Rep. 2016;6:31004. doi:10.1038/srep3100427499365
   PubMed Web of Science ®Google Scholar
• Neumann H, Vieth M, Atreya R, et al. Prospective evaluation of the learning curve of confocal laser endomicroscopy in patients with IBD. Histol Histopathol. 2011;26(7):867–872. doi:10.14670/HH-26.86721630216
   PubMed Web of Science ®Google Scholar
• Koenig K, Tanke HJ, Schneckenburger H. Laser microscopy. Proc SPIE. 2000;4164:18–27.
   Google Scholar
• König K, Schenke-Layland K, Riemann I, et al. Multiphoton autofluorescence imaging of intratissue elastic fibers. Biomaterials. 2005;26(5):495–500. doi:10.1016/j.biomaterials.2004.02.05915276357
   PubMed Web of Science ®Google Scholar
• Aggarwal A, Jain M, Frykman PK, Xu C, Mukherjee S, Muensterer OJ. Multiphoton microscopy to identify and characterize the transition zone in a mouse model of Hirschsprung disease. J Pediatr Surg. 2013;48:1288–1293. doi:10.1016/j.jpedsurg.2013.03.02523845620
   PubMed Web of Science ®Google Scholar
• Balu M, Zachary CB, Harris RM, et al. In vivo multiphoton microscopy of basal cell carcinoma. JAMA Dermatol. 2015;151(10):1068–1074. doi:10.1001/jamadermatol.2015.045325909650
   PubMed Web of Science ®Google Scholar
• Pouli D, Balu M, Alonzo CA, et al. Imaging mitochondrial dynamics in human skin reveals depth-dependent hypoxia and malignant potential for diagnosis. Sci Transl Med. 2016;8(367):367ra169. doi:10.1126/scitranslmed.aaf0746
   PubMed Web of Science ®Google Scholar
• Dimitrow E, Ziemer M, Koehler MJ, et al. Sensitivity and specificity of multiphoton laser tomography for in vivo and ex vivo diagnosis of malignant melanoma. J Invest Dermatol. 2009;129(7):1752–1758. doi:10.1038/jid.2008.43919177136
   PubMed Web of Science ®Google Scholar
• Zieger M, Springer S, Koehler MJ, Kaatz M. Multiphoton tomography. Hautarzt. 2015;66:511–521. doi:10.1007/s00105-015-3626-925943693
   PubMed Web of Science ®Google Scholar
• McHugh ML. Interrater reliability: the kappa statistic. Biochem Medica. 2012;22:276–282. doi:10.11613/BM.2012.031
   PubMed Web of Science ®Google Scholar
• Huttunen MJ, Hassan A, McCloskey CW, et al. Automated classification of multiphoton microscopy images of ovarian tissue using deep learning. J Biomed Opt. 2018;23(6):1–7. doi:10.1117/1.JBO.23.6.066002
   PubMed Web of Science ®Google Scholar
• Simon F, Schreiber P, Goedeke J, Seidmann L, Muensterer O Multiphoton microscopy: Establishing a new diagnostic method to evaluate pediatric tissues and tumors. Paper presented in part at the 135th Congress of the German Society of Surgery, Berlin, April 20, 2018
   Google Scholar
• Schreiber P. Multiphoton microscopy in the diagnostic assessment of different pediatric solid tissues in comparison to conventional histopathology [doctoral thesis]. Mainz: Johannes Gutenberg University; 2019.
   Google Scholar
• Goedeke J. Innovative new ways in diagnosis and treatment of various malignant extracranial solid tumors in childhood and adolescence [PhD thesis]. Mainz: Johannes Gutenberg University; 2019.
   Google Scholar