Diabetes mellitus is a predictive factor for radiation pneumonitis after thoracic radiotherapy in patients with lung cancer

References

• Chang JY, Senan S, Paul MA, et al. Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two randomised trials. Lancet Oncol. 2015;16(6):630–637. doi:10.1016/S1470-2045(15)70168-325981812
   PubMed Web of Science ®Google Scholar
• Rodrigues G, Lock M, D’Souza D, Yu E, Van Dyk J. Prediction of radiation pneumonitis by dose - volume histogram parameters in lung cancer – a systematic review. Radiother Oncol. 2004;71(2):127–138. doi:10.1016/j.radonc.2004.02.01515110445
   PubMed Web of Science ®Google Scholar
• Kim Y, Hong SE, Kong M, Choi J. Predictive factors for radiation pneumonitis in lung cancer treated with helical tomotherapy. Cancer Res Treat. 2013;45(4):295–302. doi:10.4143/crt.2013.45.4.29524454002
   PubMed Web of Science ®Google Scholar
• Palma DA, Senan S, Tsujino K, et al. Predicting radiation pneumonitis after chemoradiation therapy for lung cancer: an international individual patient data meta-analysis. Int J Radiat Oncol Biol Phys. 2013;85(2):444–450. doi:10.1016/j.ijrobp.2012.04.04322682812
   PubMed Web of Science ®Google Scholar
• Kim K, Lee J, Cho Y, et al. Predictive factors of symptomatic radiation pneumonitis in primary and metastatic lung tumors treated with stereotactic ablative body radiotherapy. Radiat Oncol J. 2017;35(2):163–171. doi:10.3857/roj.2017.0006628712275
   PubMedGoogle Scholar
• Shi A, Zhu G, Wu H, Yu R, Li F, Xu B. Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy. Radiat Oncol. 2010;5:35. doi:10.1186/1748-717X-5-3520462424
   PubMed Web of Science ®Google Scholar
• Boonyawan K, Gomez DR, Komaki R, et al. Clinical and dosimetric factors predicting grade >/=2 radiation pneumonitis after postoperative radiotherapy for patients with non-small cell lung carcinoma. Int J Radiat Oncol Biol Phys. 2018;101(4):919–926. doi:10.1016/j.ijrobp.2018.04.01229976504
   PubMed Web of Science ®Google Scholar
• Onishi H, Kuriyama K, Yamaguchi M, et al. Concurrent two-dimensional radiotherapy and weekly docetaxel in the treatment of stage III non-small cell lung cancer: a good local response but no good survival due to radiation pneumonitis. Lung Cancer. 2003;40(1):79–84.12660011
   PubMed Web of Science ®Google Scholar
• Parashar B, Edwards A, Mehta R, et al. Chemotherapy significantly increases the risk of radiation pneumonitis in radiation therapy of advanced lung cancer. Am J Clin Oncol. 2011;34(2):160–164. doi:10.1097/COC.0b013e3181d6b40f20498591
   PubMed Web of Science ®Google Scholar
• Zhang XJ, Sun JG, Sun J, et al. Prediction of radiation pneumonitis in lung cancer patients: a systematic review. J Cancer Res Clin Oncol. 2012;138(12):2103–2116. doi:10.1007/s00432-012-1284-122842662
   PubMed Web of Science ®Google Scholar
• Zaorsky NG, Shaikh T, Ruth K, et al. Prostate cancer patients with unmanaged diabetes or receiving insulin experience inferior outcomes and toxicities after treatment with radiation therapy. Clin Genitourin Cancer. 2017; 15(2):326–335, e323. doi:10.1016/j.clgc.2016.08.02027789181
   PubMed Web of Science ®Google Scholar
• Kalakota K, Liauw SL. Toxicity after external beam radiotherapy for prostate cancer: an analysis of late morbidity in men with diabetes mellitus. Urology. 2013;81(6):1196–1201. doi:10.1016/j.urology.2013.01.04723540863
   PubMed Web of Science ®Google Scholar
• Herold DM, Hanlon AL, Hanks GE. Diabetes mellitus: a predictor for late radiation morbidity. Int J Radiat Oncol Biol Phys. 1999;43(3):475–479. doi:10.1016/s0360-3016(98)00460-x10078625
   PubMed Web of Science ®Google Scholar
• Akimoto T, Muramatsu H, Takahashi M, et al. Rectal bleeding after hypofractionated radiotherapy for prostate cancer: correlation between clinical and dosimetric parameters and the incidence of grade 2 or worse rectal bleeding. Int J Radiat Oncol Biol Phys. 2004;60(4):1033–1039. doi:10.1016/j.ijrobp.2004.07.69515519772
   PubMed Web of Science ®Google Scholar
• Alashkham A, Paterson C, Hubbard S, Nabi G. What is the impact of diabetes mellitus on radiation induced acute proctitis after radical radiotherapy for adenocarcinoma prostate? A prospective longitudinal study. Clin Transl Radiat Oncol. 2019;14:59–63. doi:10.1016/j.ctro.2017.02.00330623118
   PubMed Web of Science ®Google Scholar
• Peairs KS, Barone BB, Snyder CF, et al. Diabetes mellitus and breast cancer outcomes: a systematic review and meta-analysis. J Clin Oncol. 2011;29(1):40–46. doi:10.1200/JCO.2009.27.301121115865
   PubMed Web of Science ®Google Scholar
• Stein KB, Snyder CF, Barone BB, et al. Colorectal cancer outcomes, recurrence, and complications in persons with and without diabetes mellitus: a systematic review and meta-analysis. Dig Dis Sci. 2010;55(7):1839–1851. doi:10.1007/s10620-009-0944-819731028
   PubMed Web of Science ®Google Scholar
• Orton MD, Mukhopadhyay ND, Weiss E. Evaluation of diabetes as a risk factor for the development of clinically symptomatic pneumonitis following Stereotactic Body Radiation Therapy (SBRT). Int J Radiat Oncol Biol Phys. 2013;87(2):S514. doi:10.1016/j.ijrobp.2013.06.1359
   Web of Science ®Google Scholar
• Zhou H, Cao K, Cao P, Jiang W. [Impact of diabetes mellitus on clinicopathological factors and relation with radiation pneumonitis in 332 patients with lung cancer]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2013;38(2):138–141. doi:10.3969/j.issn.1672-7347.2013.02.00523456072
   PubMedGoogle Scholar
• Hsia WJ, Jan N, Mukhopadhyay ND, Weiss E. Effect of diabetes mellitus and selected medications on the development of radiation pneumonitis in patients with locally advanced non-small cell lung cancer. Int J Radiat Oncol Biol Phys. 2015;93(3):E403. doi:10.1016/j.ijrobp.2015.07.1576
   Web of Science ®Google Scholar
• Song H, Yu JM. [Effect of diabetes mellitus on the development of radiation pneumonitis in patients with non-small cell lung cancer]. Zhonghua Zhong Liu Za Zhi. 2009;31(1):45–47.19538869
   PubMedGoogle Scholar
• Trott KR, Herrmann T, Kasper M. Target cells in radiation pneumopathy. Int J Radiat Oncol Biol Phys. 2004;58(2):463–469. doi:10.1016/j.ijrobp.2003.09.04514751516
   PubMed Web of Science ®Google Scholar
• Domingueti CP, Dusse LM, Carvalho M, de Sousa LP, Gomes KB, Fernandes AP. Diabetes mellitus: the linkage between oxidative stress, inflammation, hypercoagulability and vascular complications. J Diabetes Complications. 2016;30(4):738–745. doi:10.1016/j.jdiacomp.2015.12.01826781070
   PubMed Web of Science ®Google Scholar
• Meyer JS. Diabetes and wound healing. Crit Care Nurs Clin North Am. 1996;8(2):195–201.8716387
   PubMedGoogle Scholar
• Morain WD, Colen LB. Wound healing in diabetes mellitus. Clin Plast Surg. 1990;17(3):493–501.2199140
   PubMed Web of Science ®Google Scholar
• Jain V, Berman AT. Radiation pneumonitis: old problem, new tricks. Cancers (Basel). 2018;10:7. doi:10.3390/cancers10110400
   PubMed Web of Science ®Google Scholar
• Ha KH, Kim DJ. Current status of managing diabetes mellitus in Korea. Korean J Intern Med. 2016;31(5):845–850. doi:10.3904/kjim.2016.25327604796
   PubMed Web of Science ®Google Scholar
• Palmer JD, Zaorsky NG, Witek M, Lu B. Molecular markers to predict clinical outcome and radiation induced toxicity in lung cancer. J Thorac Dis. 2014;6(4):387–398. doi:10.3978/j.issn.2072-1439.2013.12.0424688783
   PubMed Web of Science ®Google Scholar
• Hartsell WF, Scott CB, Dundas GS, et al. Can serum markers be used to predict acute and late toxicity in patients with lung cancer? Analysis of RTOG 91–03. Am J Clin Oncol. 2007;30(4):368–376. doi:10.1097/01.coc.0000260950.44761.7417762437
   PubMed Web of Science ®Google Scholar
• Zhao L, Wang L, Ji W, et al. Elevation of plasma TGF-beta1 during radiation therapy predicts radiation-induced lung toxicity in patients with non-small-cell lung cancer: a combined analysis from Beijing and Michigan. Int J Radiat Oncol Biol Phys. 2009;74(5):1385–1390. doi:10.1016/j.ijrobp.2008.10.06519231104
   PubMed Web of Science ®Google Scholar
• Yuan X, Liao Z, Liu Z, et al. Single nucleotide polymorphism at rs1982073: T869Cof the TGFbeta 1 gene is associated with the risk of radiation pneumonitis in patients with non-small-cell lung cancer treated with definitive radiotherapy. J Clin Oncol. 2009;27(20):3370–3378. doi:10.1200/JCO.2008.20.676319380441
   PubMed Web of Science ®Google Scholar