Development And Validation Of A Simple Model For Detection Of Early Hepatocellular Carcinoma In A Liver Cirrhosis Cohort

References

• Grandhi MS, Kim AK, Ronnekleiv-Kelly SM, Kamel IR, Ghasebeh MA, Pawlik TM. Hepatocellular carcinoma: from diagnosis to treatment. Surg Oncol. 2016;25:74–85. doi:10.1016/j.suronc.2016.03.00227312032
   PubMed Web of Science ®Google Scholar
• Shim JJ, Oh CH, Kim JW, Lee CK, Kim BH. Liver cirrhosis stages and the incidence of hepatocellular carcinoma in chronic hepatitis B patients receiving antiviral therapy. Scand J Gastroenterol. 2017;52:1029–1036. doi:10.1080/00365521.2017.133577328562104
   PubMed Web of Science ®Google Scholar
• Altekruse SF, McGlynn KA, Reichman ME. Hepatocellular carcinoma incidence, mortality, and survival trends in the United States from 1975 to 2005. J Clin Oncol. 2009;27:1485–1491. doi:10.1200/JCO.2008.20.775319224838
   PubMed Web of Science ®Google Scholar
• Llovet JM, Zucman-Rossi J, Pikarsky E, et al. Hepatocellular carcinoma. Nat Rev Dis Primers. 2016;2:16018. doi:10.1038/nrdp.2016.1827158749
   PubMed Web of Science ®Google Scholar
• Singal AG, Pillai A, Tiro J. Early detection, curative treatment, and survival rates for hepatocellular carcinoma surveillance in patients with cirrhosis: a meta analysis. Ann Intern Med. 2014;161:261–269. doi:10.7326/M14-055824934699
   PubMedGoogle Scholar
• Heimbach JK, Kulik LM, Finn RS, et al. AASLD guidelines for the treatment of hepatocellular carcinoma. Hepatology. 2018;67:358–380. doi:10.1002/hep.2908628130846
   PubMed Web of Science ®Google Scholar
• Mokdad AA, Hester CA, Singal AG, Yopp AC. Management of hepatocellular in the United States. Chin Clin Oncol. 2017;6:21. doi:10.21037/cco28482674
   PubMed Web of Science ®Google Scholar
• Singal A, Volk M, Waljee A, et al. Meta-analysis:surveillance with ultrasound for early stage hepatocellular carcinoma in patients with cirrhosis. Aliment Pharmacol Ther. 2009;30:37–47. doi:10.1111/apt.2009.30.issue-119392863
   PubMed Web of Science ®Google Scholar
• Shang S, Plymoth A, Ge S, et al. Identification of osteopontin as a novel marker for early hepatocellular carcinoma. Hepatology. 2012;55:483–490. doi:10.1002/hep.2470321953299
   PubMed Web of Science ®Google Scholar
• Wang FH, Yip YC, Zhang M, et al. Diagnostic utility of glypican-3 for hepatocellular carcinoma on liver needle biopsy. J Clin Pathol. 2010;63:599–603. doi:10.1136/jcp.2010.07537420501450
   PubMed Web of Science ®Google Scholar
• El-Serag HB, Marrero JA, Rudolph L, Reddy KR. Diagnosis and treatment of hepatocellular carcinoma. Gastroenterology. 2008;134:1752–1763. doi:10.1053/j.gastro.2008.02.09018471552
   PubMed Web of Science ®Google Scholar
• Suzuki M, Shiraha H, Fujikawa T, et al. Des-gamma-carboxyprothrombin is a potential autologous growth factor for hepatocellular carcinoma. J Biol Chem. 2005;280:6409–6415. doi:10.1074/jbc.M40671420015582995
   PubMed Web of Science ®Google Scholar
• Zhang YS, Chu JH, Cui SX, Qu XJ. Des-γ-carboxyprothrombin (DCP) as a potential autologous growth factor for the development of hepatocellular carcinoma. Cell Physiol Biochem. 2014;34:903–915. doi:10.1159/00036630825200250
   PubMed Web of Science ®Google Scholar
• Fujikawa T, Shiraha H, Ueda N, et al. Des-gamma-carboxyl prothrombin promoted vascular endothelial cell proliferation and migration. J Biol Chem. 2007;282:8741–8748. doi:10.1074/jbc.M60935820017255102
   PubMed Web of Science ®Google Scholar
• Matsubara M, Shiraha H, Kataoka J, et al. Des-γ-carboxyl prothrombin is associated with tumor angiogenesis in hepatocellular carcinoma. J Gastroenterol Hepatol. 2012;27:1602–1608. doi:10.1111/jgh.2012.27.issue-1022554292
   PubMed Web of Science ®Google Scholar
• Poté N, Cauchy F, Albuquerque M, et al. Performance of PIVKA-II for early hepatocellular carcinoma diagnosis and prediction of microvascular invasion. J Hepatol. 2015;62:848–854. doi:10.1016/j.jhep.2014.11.00525450201
   PubMed Web of Science ®Google Scholar
• Chen H, Zhang Y, Li S, et al. Direct comparison of five serum biomarkers in early diagnosis of hepatocellular carcinoma. Cancer Manag Res. 2018;10:1947–1958. doi:10.2147/CMAR30022853
   PubMed Web of Science ®Google Scholar
• Kudo M, Izumi N, Kokudo N, et al. Management of hepatocellular carcinoma in Japan: consensus-based clinical practice guidelines proposed by the Japan Society of Hepatology (JSH) 2010 updated version. Dig Dis. 2011;29:339–364. doi:10.1159/00032757721829027
   PubMed Web of Science ®Google Scholar
• Kudo M, Matsui O, Izumi N, et al. JSH consensus-based clinical practice guidelines for the management of hepatocellular carcinoma: 2014 update by the Liver Cancer Study Group of Japan. Liver Cancer. 2014;3:458–468. doi:10.1159/00034387526280007
   PubMed Web of Science ®Google Scholar
• Song DS, Bae SH. Changes of guidelines diagnosing hepatocellular carcinoma during the last ten-year period. Clin Mol Hepatol. 2012;18:258–267. doi:10.3350/cmh.2012.18.3.25823091805
   PubMedGoogle Scholar
• Bruix J, Sherman M. Management of hepatocellular carcinoma: an update. Hepatology. 2011;53:1020–1022. doi:10.1002/hep.2419921374666
   PubMed Web of Science ®Google Scholar
• Wang X, Kwak KJ, Yang Z, et al. Extracellular mRNA detected by molecular beacons in tethered lipoplex nanoparticles for diagnosis of human hepatocellular carcinoma. PLoS One. 2018;13:e0198552. doi:10.1371/journal.pone.019855229879168
   PubMed Web of Science ®Google Scholar
• Wang X, Zhang W, Liu Y, et al. Diagnostic value of prothrombin induced by the absence of vitamin K or antagonist-II (PIVKA-II) for early stage HBV related hepatocellular carcinoma. Infect Agent Cancer. 2017;12:47. doi:10.1186/s13027-017-0153-628852419
   PubMed Web of Science ®Google Scholar
• Fujikawa T, Shirah AH, Yamamoto K. Significance of des-gamma-carboxyprothrombin production in hepatocellular carcinoma. Acta Med Okayama. 2009;63:299–304. doi:10.18926/AMO/3182620035286
   PubMed Web of Science ®Google Scholar
• Hemken PM, Sokoll LJ, Yang X, et al. Validation of a novel model for the early detection of hepatocellular carcinoma. Clin Proteomics. 2019;16:2. doi:10.1186/s12014-018-9222-030675135
   PubMed Web of Science ®Google Scholar
• Patel J, Yopp A, Waljee AK, Singal AG. Development and internal validation of a model for early detection of hepatocellular carcinoma in patients with cirrhosis. J Clin Gastroenterol. 2016;50:175–179. doi:10.1097/MCG.000000000000037726125462
   PubMed Web of Science ®Google Scholar
• Lok AS, Sterling RK, Everhart JE, et al. Des-gamma-carboxy prothrombin and alpha-fetoprotein as biomarkers for the early detection of hepatocellular carcinoma. Gastroenterology. 2010;138:493–502. doi:10.1053/j.gastro.2009.10.03119852963
   PubMed Web of Science ®Google Scholar