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Original Research

High Expression of MDM2 and the p53 Protein is Predictive Biomarkers for Poor Prognosis of Oesophageal Squamous Cell Carcinoma

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Pages 2733-2744 | Published online: 23 Mar 2021

References

  • Malhotra GK, Yanala U, Ravipati A, Follet M, Vijayakumar M, Are C. Global trends in esophageal cancer. J Surg Oncol. 2017;115(5):564–579. doi:10.1002/jso.2459228320055
  • Di Pardo BJ, Bronson NW, Diggs BS, Thomas CR, Hunter JG, Dolan JP. The global burden of esophageal cancer: a disability-adjusted life-year approach. World J Surg. 2016;40(2):395–401. doi:10.1007/s00268-015-3356-226630937
  • Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424. doi:10.3322/caac.2149230207593
  • Liang H, Fan JH, Qiao YL. Epidemiology, etiology, and prevention of esophageal squamous cell carcinoma in China. Cancer Biol Med. 2017;14(1):33–41. doi:10.20892/j.issn.2095-3941.2016.009328443201
  • Daly JM, Fry WA, Little AG, et al. Esophageal cancer: results of an American college of surgeons patient care evaluation study. J Am Coll Surg. 2000;190(5):562–572; discussion 572–563. doi:10.1016/S1072-7515(00)00238-6
  • Abnet CC, Arnold M, Wei WQ. Epidemiology of esophageal squamous cell carcinoma. Gastroenterology. 2018;154(2):360–373. doi:10.1053/j.gastro.2017.08.02328823862
  • Shan L, Yu J, He Z, et al. Defining relative mutational difficulty to understand cancer formation. Cell Discov. 2020;6:48. doi:10.1038/s41421-020-0177-832704382
  • Yan W, Wistuba II, Emmert-Buck MR, Erickson HS. Squamous cell carcinoma - similarities and differences among anatomical sites. Am J Cancer Res. 2011;1(3):275–300. doi:10.1158/1538-7445.am2011-27521938273
  • He LR, Liu MZ, Li BK, et al. High expression of EZH2 is associated with tumor aggressiveness and poor prognosis in patients with esophageal squamous cell carcinoma treated with definitive chemoradiotherapy. Int J Cancer. 2010;127(1):138–147. doi:10.1002/ijc.2503119904743
  • Smyth EC, Lagergren J, Fitzgerald RC, et al. Oesophageal cancer. Nat Rev Dis Primers. 2017;3:17048.28748917
  • Lane DP, Crawford LV. T antigen is bound to a host protein in SV40-transformed cells. Nature. 1979;278(5701):261–263. doi:10.1038/278261a0218111
  • Shi L, Tian Q, Feng C, Zhang P, Zhao Y. The biological function and the regulatory roles of wild-type p53-induced phosphatase 1 in immune system. Int Rev Immunol. 2020;1–12.
  • Zhang Y, Qian M, Tang F, et al. Identification and analysis of p53-regulated enhancers in hepatic carcinoma. Front Bioeng Biotechnol. 2020;8:668. doi:10.3389/fbioe.2020.0066832695760
  • Joerger AC, Fersht AR. The p53 pathway: origins, inactivation in cancer, and emerging therapeutic approaches. Annu Rev Biochem. 2016;85:375–404. doi:10.1146/annurev-biochem-060815-01471027145840
  • Oren M, Levine AJ. Molecular cloning of a cDNA specific for the murine p53 cellular tumor antigen. Proc Natl Acad Sci U S A. 1983;80(1):56–59. doi:10.1073/pnas.80.1.566296874
  • Garty H, Klemperer G, Eisenbach M, Caplan SR. The direction of light-induced pH changes in purple membrane suspensions. Influence of pH and temperature. FEBS Lett. 1977;81(2):238–242. doi:10.1016/0014-5793(77)80526-721811
  • Qin JJ, Li X, Hunt C, Wang W, Wang H, Zhang R. Natural products targeting the p53-MDM2 pathway and mutant p53: recent advances and implications in cancer medicine. Genes Dis. 2018;5(3):204–219. doi:10.1016/j.gendis.2018.07.00230320185
  • Wang S, Zhao Y, Aguilar A, Bernard D, Yang CY. Targeting the MDM2-p53 protein-protein interaction for new cancer therapy: progress and challenges. Cold Spring Harb Perspect Med. 2017;7(5):a026245. doi:10.1101/cshperspect.a02624528270530
  • Oliner JD, Saiki AY, Caenepeel S. The role of MDM2 amplification and overexpression in tumorigenesis. Cold Spring Harb Perspect Med. 2016;6(6):a026336. doi:10.1101/cshperspect.a02633627194168
  • Chen Y, Wang DD, Wu YP, et al. MDM2 promotes epithelial-mesenchymal transition and metastasis of ovarian cancer SKOV3 cells. Br J Cancer. 2017;117(8):1192–1201. doi:10.1038/bjc.2017.26528817834
  • Wang BY, Cao J, Chen JW, Liu QY. Triptolide induces apoptosis of gastric cancer cells via inhibiting the overexpression of MDM2. Med Oncol. 2014;31(11):270. doi:10.1007/s12032-014-0270-725280518
  • Wu B, Chu X, Feng C, et al. Heat shock protein gp96 decreases p53 stability by regulating Mdm2 E3 ligase activity in liver cancer. Cancer Lett. 2015;359(2):325–334. doi:10.1016/j.canlet.2015.01.03425637791
  • Sheng W, Dong M, Chen C, et al. Cooperation of Musashi-2, Numb, MDM2, and P53 in drug resistance and malignant biology of pancreatic cancer. FASEB J. 2017;31(6):2429–2438. doi:10.1096/fj.201601240R28223335
  • Su HC, Wu SC, Yen LC, et al. Gene expression profiling identifies the role of Zac1 in cervical cancer metastasis. Sci Rep. 2020;10(1):11837. doi:10.1038/s41598-020-68835-032678267
  • Zheng H, Tie Y, Fang Z, et al. Jumonji domain-containing 6 (JMJD6) identified as a potential therapeutic target in ovarian cancer. Signal Transduct Target Ther. 2019;4(1):24. doi:10.1038/s41392-019-0055-831637004
  • Merten L, Agaimy A, Moskalev EA, et al. Inactivating mutations of RB1 and TP53 correlate with sarcomatous histomorphology and metastasis/recurrence in gastrointestinal stromal tumors. Am J Clin Pathol. 2016;146(6):718–726. doi:10.1093/ajcp/aqw19328028119
  • Michalk M, Meinrath J, Kunstlinger H, et al. MDM2 gene amplification in esophageal carcinoma. Oncol Rep. 2016;35(4):2223–2227. doi:10.3892/or.2016.457826796597
  • Zhang YS, Shen Q, Li J. Traditional Chinese medicine targeting apoptotic mechanisms for esophageal cancer therapy. Acta Pharmacol Sin. 2016;37(3):295–302. doi:10.1038/aps.2015.11626707140
  • Konopleva M, Martinelli G, Daver N, et al. MDM2 inhibition: an important step forward in cancer therapy. Leukemia. 2020;34(11):2858–2874. doi:10.1038/s41375-020-0949-z32651541
  • Sawada R, Maehara R, Oshikiri T, et al. MDM2 copy number increase: a poor prognostic, molecular event in esophageal squamous cell carcinoma. Hum Pathol. 2019;89:1–9. doi:10.1016/j.humpath.2019.04.00231004651
  • Shimada H. p53 molecular approach to diagnosis and treatment of esophageal squamous cell carcinoma. Ann Gastroenterol Surg. 2018;2(4):266–273. doi:10.1002/ags3.1217930003189
  • Sankalecha TH, Gupta SJ, Gaikwad NR, Shirole NU, Kothari HG. Yield of p53 expression in esophageal squamous cell cancer and its relationship with survival. Saudi J Gastroenterol. 2017;23(5):281–286. doi:10.4103/sjg.SJG_56_1728937022
  • Hong Y, Miao X, Zhang X, et al. The role of P53 and MDM2 polymorphisms in the risk of esophageal squamous cell carcinoma. Cancer Res. 2005;65(20):9582–9587. doi:10.1158/0008-5472.CAN-05-146016230424
  • Cheng TH, Hsu PK, Li AF, Hung IC, Huang MH, Hsu HS. Correlation of p53, MDM2 and p14(ARF) protein expression in human esophageal squamous cell carcinoma. J Cancer Res Clin Oncol. 2009;135(11):1577–1582. doi:10.1007/s00432-009-0605-519488782
  • Köbel M, Ronnett BM, Singh N, Soslow RA, Gilks CB, McCluggage WG. Interpretation of P53 immunohistochemistry in endometrial carcinomas: toward increased reproducibility. Int J Gynecol Pathol. 2019;38(Suppl 1):S123–s131. doi:10.1097/PGP.000000000000048829517499
  • Lee JM, Shun CT, Wu MT, et al. The associations of p53 overexpression with p53 codon 72 genetic polymorphism in esophageal cancer. Mutat Res. 2006;594(1–2):181–188. doi:10.1016/j.mrfmmm.2005.09.00316318864