Therapeutic Options in Unresectable Oral Squamous Cell Carcinoma: A Systematic Review

References

• DalyB, BatchelorP, TreasureE. Introduction to the principles of public health. In: Essential Dental Public Health. Vol. 2. Oxford: Oxford University Press; 2013:1–48.
   Google Scholar
• SiegelRL, MillerKD, JemalA. Cancer Statistics, 2017. CA Cancer J Clin. 2017;67(1):7–30. doi:10.3322/caac.2138728055103
   PubMed Web of Science ®Google Scholar
• BrayF, FerlayJ, SoerjomataramI, SiegelRL, TorreLA, JemalA. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424. doi:10.3322/caac.2149230207593
   PubMed Web of Science ®Google Scholar
• WarnakulasuriyaS. Global epidemiology of oral and oropharyngeal cancer. Oral Oncol. 2009;45(4–5):309–316. doi:10.1016/j.oraloncology.2008.06.00218804401
   PubMed Web of Science ®Google Scholar
• KyrgiasG, HajiioannouJ, ToliaM, et al. Intraoperative radiation therapy (IORT) in head and neck cancer: a systematic review. Medicine (Baltimore). 2016;95(50):e5035. doi:10.1097/MD.000000000000503527977569
   PubMed Web of Science ®Google Scholar
• KochL, JansenL, BrennerH, ArndtV. Fear of recurrence and disease progression in long-term (≥ 5 years) cancer survivors–a systematic review of quantitative studies. Psycho-Oncol. 2013;22(1):1–11. doi:10.1002/pon.3022
   PubMed Web of Science ®Google Scholar
• DziobaA, AaltoD, Papadopoulos-NydamG, et al. Functional and quality of life outcomes after partial glossectomy: a multi-institutional longitudinal study of the head and neck research network. J Otolaryngol Head Neck Surgery. 2017;46(1):56. doi:10.1186/s40463-017-0234-y
   PubMed Web of Science ®Google Scholar
• WongT, WiesenfeldD. Oral cancer. Aust Dent J. 2018;63(Suppl 1):S91–s99. doi:10.1111/adj.1259429574808
   PubMed Web of Science ®Google Scholar
• HartnerL. Chemotherapy for oral cancer. Dent Clin North Am. 2018;62(1):87–97. doi:10.1016/j.cden.2017.08.00629126496
   PubMedGoogle Scholar
• BulsaraVM, WorthingtonHV, GlennyA-M, ClarksonJE, ConwayDI, MacluskeyM. Interventions for the treatment of oral and oropharyngeal cancers: surgical treatment. Cochrane Database Syst Rev. 2018;12(12):CD006205–CD006205.30582609
   PubMed Web of Science ®Google Scholar
• WolffKD, FollmannM, NastA. The diagnosis and treatment of oral cavity cancer. Dtsch Arztebl Int. 2012;109(48):829–835.23248713
   PubMed Web of Science ®Google Scholar
• GrégoireV, LeroyR, HeusP, et al. Oral cavity cancer: diagnosis, treatment and follow-up. Good clinical practice (GCP) Brussels: Belgian health care knowledge centre (KCE). KCE Rep. 2014:227. Available from: https://kce.fgov.be/sites/default/files/atoms/files/KCE_227Cs_oral%20cavity%20cancer_Synthesis_2.pdf.
   Google Scholar
• AlzahraniR, ObaidA, Al-HakamiH, et al. Locally advanced oral cavity cancers: what is the optimal care?Cancer Control. 2020;27(1):1073274820920727. doi:10.1177/107327482092072732339002
   PubMed Web of Science ®Google Scholar
• MaderaM, FrancoJ, BallesterosM, SolàI, UrrútiaG, BonfillX. Evidence mapping and quality assessment of systematic reviews on therapeutic interventions for oral cancer. Cancer Manag Res. 2019;11:117–130. doi:10.2147/CMAR.S18670030636891
   PubMed Web of Science ®Google Scholar
• PageMJ, McKenzieJE, BossuytPM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71. doi:10.1136/bmj.n7133782057
   PubMed Web of Science ®Google Scholar
• OuzzaniM, HammadyH, FedorowiczZ, ElmagarmidA. Rayyan-a web and mobile app for systematic reviews. Syst Rev. 2016;5(1):210. doi:10.1186/s13643-016-0384-427919275
   PubMedGoogle Scholar
• MoolaS, MunnZ, TufanaruC, et al. Chapter 7: systematic reviews of etiology and risk. In: AromatarisE, MunnZ, editors. JBI Manual for Evidence Synthesis. 2020. Available from: https://synthesismanual.jbi.global. Accessed 816, 2021.
   Google Scholar
• BazykaD, VorobyovM, KechynI, VorobyovO, ShmykovaO. Radiothermometric personalisation of chemo- and radiotherapy for patients with advanced (III, IVa and IVb) stages malignant lesions of oral cavity, throat and epiglottis. Problemy Radiatsiinoi Medytsyny Ta Radiobiolohii. 2019;24:296–311. doi:10.33145/2304-8336-2019-24-296-31131841475
   PubMedGoogle Scholar
• BiswasR, HalderA, GhoshA, GhoshSK. A comparative study of treatment outcome in younger and older patients with locally advanced oral cavity and oropharyngeal cancers treated by chemoradiation. South Asian j Cancer. 2019;8(1):47–51. doi:10.4103/sajc.sajc_7_1830766854
   PubMed Web of Science ®Google Scholar
• ChangPM, LuHJ, WangLW, et al. Effectiveness of incorporating cetuximab into docetaxel/cisplatin/fluorouracil induction chemotherapy and chemoradiotherapy for inoperable squamous cell carcinoma of the oral cavity: a phase II study. Head Neck. 2017;39(7):1333–1342. doi:10.1002/hed.2476628370774
   PubMed Web of Science ®Google Scholar
• ChhatuiB, DevleenaRS, MajiT, LahiriD, BiswasJ. Immunomodulated anterior chemotherapy followed by concurrent chemoradiotherapy in locally advanced tongue cancer: an Institutional experience. Indian J Med Paediatr Oncol. 2015;36(1):43–48. doi:10.4103/0971-5851.15178225810574
   PubMedGoogle Scholar
• ChitapanaruxI, TraisathitP, KomolmalaiN, et al. Ten-year outcome of different treatment modalities for squamous cell carcinoma of oral cavity. Asian Pacific j Cancer Prevention. 2017;18(7):1919–1924.
   PubMedGoogle Scholar
• DonatoV, CianciulliM, FourakiS, et al. Helical tomotherapy: an innovative radiotherapy technique for the treatment of locally advanced oropharynx and inoperable oral cavity carcinoma. Radiation Oncol. 2013;8:210. doi:10.1186/1748-717X-8-210
   PubMed Web of Science ®Google Scholar
• ElbersJBW, Al-MamganiA, PapingD, et al. Definitive (chemo) radiotherapy is a curative alternative for standard of care in advanced stage squamous cell carcinoma of the oral cavity. Oral Oncol. 2017;75:163–168. doi:10.1016/j.oraloncology.2017.11.00629224815
   PubMed Web of Science ®Google Scholar
• FosterCC, MelotekJM, BrissonRJ, et al. Definitive chemoradiation for locally-advanced oral cavity cancer: a 20-year experience. Oral Oncol. 2018;80:16–22. doi:10.1016/j.oraloncology.2018.03.00829706184
   PubMed Web of Science ®Google Scholar
• HayashiY, OsawaK, NakakajiR, et al. Prognostic factors and treatment outcomes of advanced maxillary gingival squamous cell carcinoma treated by intra-arterial infusion chemotherapy concurrent with radiotherapy. Head Neck. 2019;41(6):1777–1784. doi:10.1002/hed.2560730694002
   PubMed Web of Science ®Google Scholar
• HinoS, HamakawaH, MiyamotoY, et al. Effects of a concurrent chemoradiotherapy with S-1 for locally advanced oral cancer. Oncol Lett. 2011;2(5):839–843.22866137
   PubMed Web of Science ®Google Scholar
• IqbalH, JamshedA, BhattiAB, et al. Five-year follow-up of concomitant accelerated hypofractionated radiation in advanced squamous cell carcinoma of the buccal mucosa: a retrospective cohort study. Biomed Res Int. 2015;2015:963574. doi:10.1155/2015/96357426075278
   PubMed Web of Science ®Google Scholar
• LarizadehMH, ShabaniM. Survival following non surgical treatments for oral cancer: a single institutional result. Asian Pacific j Cancer Prevention. 2012;13(8):4133–4136. doi:10.7314/APJCP.2012.13.8.4133
   PubMedGoogle Scholar
• LiY, LiLJ, WangLJ, et al. Selective intra-arterial infusion of rAd-p53 with chemotherapy for advanced oral cancer: a randomized clinical trial. BMC Med. 2014;12:16. doi:10.1186/1741-7015-12-1624479409
   PubMed Web of Science ®Google Scholar
• MengJ, GuQP, MengQF, et al. Efficacy of nimotuzumab combined with docetaxel-cisplatin-fluorouracil regimen in treatment of advanced oral carcinoma. Cell Biochem Biophys. 2014;68(1):181–184. doi:10.1007/s12013-013-9686-523733674
   PubMed Web of Science ®Google Scholar
• MurakamiR, SembaA, KawaharaK, et al. Concurrent chemoradiotherapy with S-1 in patients with stage III-IV oral squamous cell carcinoma: a retrospective analysis of nodal classification based on the neck node level. Mol Clin Oncol. 2017;7(1):140–144. doi:10.3892/mco.2017.127628685092
   PubMed Web of Science ®Google Scholar
• OyamaT, HosokawaY, AbeK, et al. Prognostic value of quantitative FDG-PET in the prediction of survival and local recurrence for patients with advanced oral cancer treated with superselective intra-arterial chemoradiotherapy. Oncol Lett. 2020;19(6):3775–3780.32382329
   PubMed Web of Science ®Google Scholar
• PatilVM, PrabhashK, NoronhaV, et al. Neoadjuvant chemotherapy followed by surgery in very locally advanced technically unresectable oral cavity cancers. Oral Oncol. 2014;50(10):1000–1004. doi:10.1016/j.oraloncology.2014.07.01525130412
   PubMed Web of Science ®Google Scholar
• PedersonAW, SalamaJK, WittME, et al. Concurrent chemotherapy and intensity-modulated radiotherapy for organ preservation of locoregionally advanced oral cavity cancer. Am J Clin Oncol. 2011;34(4):356–361. doi:10.1097/COC.0b013e3181e8420b21633289
   PubMed Web of Science ®Google Scholar
• RewadkarMS, MahobiaVK. Impact of induction chemotherapy to concurrent chemoirradiation over radiotherapy alone in advanced oral cavity. Indian J Cancer. 2017;54(1):16–19. doi:10.4103/ijc.IJC_166_1729199654
   PubMed Web of Science ®Google Scholar
• RudreshaAH, ChaudhuriT, LakshmaiahKC, et al. Induction chemotherapy in technically unresectable locally advanced t4a oral cavity squamous cell cancers: experience from a regional cancer center of South India. Indian J Med Paediatr Oncol. 2017;38(4):490–494. doi:10.4103/ijmpo.ijmpo_185_1629333018
   PubMed Web of Science ®Google Scholar
• RudreshaAH, ChaudhuriT, LakshmaiahKC, et al. Induction chemotherapy in locally advanced T4b oral cavity squamous cell cancers: a regional cancer center experience. Indian J Cancer. 2017;54(1):35–38. doi:10.4103/ijc.IJC_131_1729199659
   PubMed Web of Science ®Google Scholar
• SantosMA, GuinotJL, TortajadaMI, et al. High-dose-rate interstitial brachytherapy boost in inoperable locally advanced tongue carcinoma. Brachytherapy. 2017;16(6):1213–1218. doi:10.1016/j.brachy.2017.07.00628807749
   PubMed Web of Science ®Google Scholar
• SatoK, HayashiY, WatanabeK, YoshimiR, HibiH. Concurrent chemoradiotherapy with intravenous cisplatin and docetaxel for advanced oral cancer. Nagoya J Med Sci. 2019;81(3):407–414.31579331
   PubMed Web of Science ®Google Scholar
• ScherED, RomesserPB, ChenC, et al. Definitive chemoradiation for primary oral cavity carcinoma: a single institution experience. Oral Oncol. 2015;51(7):709–715. doi:10.1016/j.oraloncology.2015.04.00725958830
   PubMed Web of Science ®Google Scholar
• ShiaBC, QinL, LinKC, et al. Outcomes for elderly patients aged 70 to 80 years or older with locally advanced oral cavity squamous cell carcinoma: a propensity score-matched, nationwide, oldest old patient-based cohort study. Cancers. 2020;12(2):258. doi:10.3390/cancers12020258.
   PubMed Web of Science ®Google Scholar
• SinghK, DixitA, PrashadS, SaxenaT, ShahooD, SharmaD. A randomized trial comparing radiotherapy alone versus radiotherapy with gefitinib in locally advance oral cavity cancer. Clin Cancer Investigation J. 2013;2:29–33. doi:10.4103/2278-0513.110768
   Google Scholar
• Takácsi-NagyZ, ObernaF, KoltaiP, et al. Long-term outcomes with high-dose-rate brachytherapy for the management of base of tongue cancer. Brachytherapy. 2013;12(6):535–541. doi:10.1016/j.brachy.2013.07.00123988507
   PubMed Web of Science ®Google Scholar
• TakayamaK, NakamuraT, TakadaA, et al. Treatment results of alternating chemoradiotherapy followed by proton beam therapy boost combined with intra-arterial infusion chemotherapy for stage III-IVB tongue cancer. J Cancer Res Clin Oncol. 2016;142(3):659–667. doi:10.1007/s00432-015-2069-026521257
   PubMed Web of Science ®Google Scholar
• VedasoundaramP, RaghavaKA, PeriasamyK, et al. The effect of high dose rate interstitial implant on early and locally advanced oral cavity cancers: update and long-term follow-up study. Cureus. 2020;12(5):e7910.32494525
   PubMed Web of Science ®Google Scholar
• WuCF, ChangKP, HuangCJ, ChenCM, ChenCY, Steve LinCL. Continuous intra-arterial chemotherapy for downstaging locally advanced oral commissure carcinoma. Head Neck. 2014;36(7):1027–1033. doi:10.1002/hed.2340823784874
   PubMed Web of Science ®Google Scholar
• YenCJ, TsouHH, HsiehCY, et al. Sequential therapy of neoadjuvant biochemotherapy with cetuximab, paclitaxel, and cisplatin followed by cetuximab-based concurrent bioradiotherapy in high-risk locally advanced oral squamous cell carcinoma: final analysis of a Phase 2 clinical trial. Head Neck. 2019;41(6):1703–1712. doi:10.1002/hed.2564030636183
   PubMed Web of Science ®Google Scholar
• ZaidiSHM, MasoodAI, ShahSIH, HashemyI. Open label, non-randomized, interventional study to evaluate response rate after induction therapy with docetaxel and cisplatin in locally advanced squamous cell carcinoma of oral cavity. Gulf J Oncol. 2020;1(32):12–28.
   PubMedGoogle Scholar
• ZhangH, DziegielewskiPT, BironVL, et al. Survival outcomes of patients with advanced oral cavity squamous cell carcinoma treated with multimodal therapy: a multi-institutional analysis. J Otolaryngol. 2013;42(1):30. doi:10.1186/1916-0216-42-30
   Google Scholar
• Müller-RichterU, BetzC, HartmannS, BrandsRC. Nutrition management for head and neck cancer patients improves clinical outcome and survival. Nutr Res. 2017;48:1–8. doi:10.1016/j.nutres.2017.08.00729246276
   PubMed Web of Science ®Google Scholar
• TomarSL, LoreeM, LoganH. Racial differences in oral and pharyngeal cancer treatment and survival in Florida. Cancer Causes Control. 2004;15(6):601–609. doi:10.1023/B:CACO.0000036166.21056.f915280639
   PubMed Web of Science ®Google Scholar
• ZakeriK, MacEwanI, VazirniaA, et al. Race and competing mortality in advanced head and neck cancer. Oral Oncol. 2014;50(1):40–44. doi:10.1016/j.oraloncology.2013.09.01224134948
   PubMed Web of Science ®Google Scholar
• ShantiRM, O’MalleyBWJr. Surgical management of oral cancer. Dent Clin North Am. 2018;62(1):77–86. doi:10.1016/j.cden.2017.08.00529126495
   PubMedGoogle Scholar
• ZanoniDK, MonteroPH, MigliacciJC, et al. Survival outcomes after treatment of cancer of the oral cavity (1985–2015). Oral Oncol. 2019;90:115–121. doi:10.1016/j.oraloncology.2019.02.00130846169
   PubMed Web of Science ®Google Scholar
• SylvesterRJ, CanfieldSE, LamTB, et al. Conflict of evidence: resolving discrepancies when findings from randomized controlled trials and meta-analyses disagree. Eur Urol. 2017;71(5):811–819. doi:10.1016/j.eururo.2016.11.02327914898
   PubMed Web of Science ®Google Scholar
• Alonso-CoelloP, SchunemannHJ, MobergJ, et al. GRADE evidence to decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 1: introduction. BMJ. 2016;353:i2016. doi:10.1136/bmj.i201627353417
   PubMed Web of Science ®Google Scholar
• SunW, ShiQ, ZhangH, et al. Advances in the techniques and methodologies of cancer gene therapy. Discov Med. 2019;27(146):45–55.30721651
   PubMed Web of Science ®Google Scholar
• FarmerZL, KimES, CarrizosaDR. Gene therapy in head and neck cancer. Oral Maxillofac Surg Clin North Am. 2019;31(1):117–124. doi:10.1016/j.coms.2018.08.00630454787
   PubMed Web of Science ®Google Scholar
• PerrottiV, CaponioVCA, MascittiM, et al. Therapeutic potential of antibody-drug conjugate-based therapy in head and neck cancer: a systematic review. Cancers. 2021;13:13. doi:10.3390/cancers13133126
   Web of Science ®Google Scholar