Upregulation of Linc-ROR Promotes the Proliferation, Migration, and Invasion of Gastric Cancer Cells Through miR-212-3p/FGF7 Axis

References

• Siegel RL, Miller KD, Jemal A. Cancer statistics, 2019. CA Cancer J Clin. 2019;69(1):7–34. doi:10.3322/caac.2155130620402
   PubMed Web of Science ®Google Scholar
• Miller KD, Nogueira L, Mariotto AB, et al. Cancer treatment and survivorship statistics, 2019. CA Cancer J Clin. 2019;69(5):363–385. doi:10.3322/caac.2156531184787
   PubMed Web of Science ®Google Scholar
• Karimi P, Islami F, Anandasabapathy S, Freedman ND, Kamangar F. Gastric cancer: descriptive epidemiology, risk factors, screening, and prevention. Cancer Epidemiol Biomarkers Prev. 2014;23(5):700–713. doi:10.1158/1055-9965.EPI-13-105724618998
   PubMed Web of Science ®Google Scholar
• Obermannova R, Lordick F. Management of metastatic gastric cancer. Hematol Oncol Clin North Am. 2017;31(3):469–483. doi:10.1016/j.hoc.2017.01.00628501088
   PubMed Web of Science ®Google Scholar
• Yan Y, Wang LF, Wang RF. Role of cancer-associated fibroblasts in invasion and metastasis of gastric cancer. World J Gastroenterol. 2015;21(33):9717–9726. doi:10.3748/wjg.v21.i33.971726361418
   PubMed Web of Science ®Google Scholar
• Abbas M, Habib M, Naveed M, et al. The relevance of gastric cancer biomarkers in prognosis and pre- and post-chemotherapy in clinical practice. Biomed Pharmacother. 2017;95:1082–1090. doi:10.1016/j.biopha.2017.09.03228922727
   PubMed Web of Science ®Google Scholar
• Chen LT, Oh DY, Ryu MH, et al. Anti-angiogenic therapy in patients with advanced gastric and gastroesophageal junction cancer: a systematic review. Cancer Res Treat. 2017;49(4):851–868. doi:10.4143/crt.2016.17628052652
   PubMed Web of Science ®Google Scholar
• Cavatorta O, Scida S, Miraglia C, et al. Epidemiology of gastric cancer and risk factors. Acta bio-medica: Atenei Parmensis. 2018;89(8–s):82–87. doi:10.23750/abm.v89i8-S.796630561423
   PubMedGoogle Scholar
• Kashihara H, Shimada M, Yoshikawa K, et al. Risk factors for recurrence of gastric cancer after curative laparoscopic gastrectomy. J Med Invest. 2017;64(1.2):79–84. doi:10.2152/jmi.64.7928373634
   PubMed Web of Science ®Google Scholar
• Choi YJ, Kim N. Gastric cancer and family history. Korean J Intern Med. 2016;31(6):1042–1053. doi:10.3904/kjim.2016.14727809451
   PubMed Web of Science ®Google Scholar
• Li W, Xu C, Guo J, et al. Cis- and trans-acting expression quantitative trait loci of long non-coding RNA in 2,549 cancers with potential clinical and therapeutic implications. Front Oncol. 2020;10:602104. doi:10.3389/fonc.2020.60210433194770
   PubMed Web of Science ®Google Scholar
• Bhan A, Soleimani M, Mandal SS. Long noncoding RNA and cancer: a new paradigm. Cancer Res. 2017;77(15):3965–3981. doi:10.1158/0008-5472.CAN-16-263428701486
   PubMed Web of Science ®Google Scholar
• Wang Y, Xu Z, Jiang J, et al. Endogenous miRNA sponge lincRNA-RoR regulates Oct4, Nanog, and Sox2 in human embryonic stem cell self-renewal. Dev Cell. 2013;25(1):69–80. doi:10.1016/j.devcel.2013.03.00223541921
   PubMed Web of Science ®Google Scholar
• Chen W, Wang H, Liu Y, et al. Linc-RoR promotes proliferation, migration, and invasion via the Hippo/YAP pathway in pancreatic cancer cells. J Cell Biochem. 2020;121(1):632–641. doi:10.1002/jcb.2930831452251
   PubMed Web of Science ®Google Scholar
• Huang J, Zhang A, Ho TT, et al. Linc-RoR promotes c-Myc expression through hnRNP I and AUF1. Nucleic Acids Res. 2016;44(7):3059–3069. doi:10.1093/nar/gkv135326656491
   PubMed Web of Science ®Google Scholar
• Deng K, Wang H, Guo X, Xia J. The cross talk between long, non-coding RNAs and microRNAs in gastric cancer. Acta Biochim Biophys Sin (Shanghai). 2016;48(2):111–116. doi:10.1093/abbs/gmv12026621794
   PubMed Web of Science ®Google Scholar
• Hayes J, Peruzzi PP, Lawler S. MicroRNAs in cancer: biomarkers, functions and therapy. Trends Mol Med. 2014;20(8):460–469. doi:10.1016/j.molmed.2014.06.00525027972
   PubMed Web of Science ®Google Scholar
• Jonas S, Izaurralde E. Towards a molecular understanding of microRNA-mediated gene silencing. Nat Rev Genet. 2015;16(7):421–433. doi:10.1038/nrg396526077373
   PubMed Web of Science ®Google Scholar
• Huntzinger E, Izaurralde E. Gene silencing by microRNAs: contributions of translational repression and mRNA decay. Nat Rev Genet. 2011;12(2):99–110. doi:10.1038/nrg293621245828
   PubMed Web of Science ®Google Scholar
• Wang D, Zheng J, Liu X, et al. Knockdown of USF1 inhibits the vasculogenic mimicry of glioma cells via stimulating SNHG16/miR-212-3p and linc00667/miR-429 axis. Mol Ther Nucleic Acids. 2019;14:465–482. doi:10.1016/j.omtn.2018.12.01730743215
   PubMedGoogle Scholar
• Wu R, Li F, Zhu J, et al. A functional variant at miR-132-3p, miR-212-3p, and miR-361-5p binding site in CD80 gene alters susceptibility to gastric cancer in a Chinese Han population. Med Oncol. 2014;31(8):60. doi:10.1007/s12032-014-0060-224981235
   PubMed Web of Science ®Google Scholar
• Qiu HB, Yang K, Yu HY, Liu M. Downregulation of long non-coding RNA XIST inhibits cell proliferation, migration, invasion and EMT by regulating miR-212-3p/CBLL1 axis in non-small cell lung cancer cells. Eur Rev Med Pharmacol Sci. 2019;23(19):8391–8402. doi:10.26355/eurrev_201910_1915031646569
   PubMed Web of Science ®Google Scholar
• Wu X, Chen H, Zhang G, et al. MiR-212-3p inhibits cell proliferation and promotes apoptosis by targeting nuclear factor IA in bladder cancer. J Biosci. 2019;44:4. doi:10.1007/s12038-019-9903-530837356
   PubMed Web of Science ®Google Scholar
• Dang Y, Liu T, Yan J, et al. Gastric cancer proliferation and invasion is reduced by macrocalyxin C via activation of the miR-212-3p/Sox6 pathway. Cell Signal. 2019;66:109430. doi:10.1016/j.cellsig.2019.10943031726103
   PubMed Web of Science ®Google Scholar
• Wang X, Ye T, Xue B, et al. Mitochondrial GRIM-19 deficiency facilitates gastric cancer metastasis through oncogenic ROS-NRF2-HO-1 axis via a NRF2-HO-1 loop. Gastric Cancer. 2020.
   Web of Science ®Google Scholar
• Ye T, Yang M, Huang D, et al. MicroRNA-7 as a potential therapeutic target for aberrant NF-κB-driven distant metastasis of gastric cancer. J Exp Clin Cancer Res. 2019;38(1):55. doi:10.1186/s13046-019-1074-630728051
   PubMed Web of Science ®Google Scholar
• Wang L, Yu X, Zhang Z, et al. Linc-ROR promotes esophageal squamous cell carcinoma progression through the derepression of SOX9. J Exp Clin Cancer Res. 2017;36(1):182. doi:10.1186/s13046-017-0658-229237490
   PubMed Web of Science ®Google Scholar
• Sahebi R, Malakootian M, Balalaee B, et al. Linc-ROR and its spliced variants 2 and 4 are significantly up-regulated in esophageal squamous cell carcinoma. Iran J Basic Med Sci. 2016;19(10):1131–1135.27872710
   PubMed Web of Science ®Google Scholar
• Liu H, Li C, Shen C, et al. MiR-212-3p inhibits glioblastoma cell proliferation by targeting SGK3. J Neurooncol. 2015;122(3):431–439. doi:10.1007/s11060-015-1736-y25720694
   PubMed Web of Science ®Google Scholar
• Hou P, Kang Y, Luo J. Hypoxia-mediated miR-212-3p downregulation enhances progression of intrahepatic cholangiocarcinoma through upregulation of Rab1a. Cancer Biol Ther. 2018;19(11):984–993. doi:10.1080/15384047.2018.145660829672195
   PubMed Web of Science ®Google Scholar
• Lu X, Wang F, Fu M, Li Y, Wang L. Long non-coding RNA KCNQ1OT1 accelerates the progression of ovarian cancer via microRNA-212-3/LCN2 axis. Oncol Res. 2019. doi:10.3727/096504019X15719983040135
   Web of Science ®Google Scholar
• He L, Qu L, Wei L, Chen Y, Suo J. Reduction of miR1323p contributes to gastric cancer proliferation by targeting MUC13. Mol Med Rep. 2017;15(5):3055–3061. doi:10.3892/mmr.2017.634728339011
   PubMed Web of Science ®Google Scholar
• Fan EW, Li CC, Wu WJ, et al. FGF7 over expression is an independent prognosticator in patients with urothelial carcinoma of the upper urinary tract and bladder. J Urol. 2015;194(1):223–229. doi:10.1016/j.juro.2015.01.07325623741
   PubMed Web of Science ®Google Scholar
• Huang T, Wang L, Liu D, et al. FGF7/FGFR2 signal promotes invasion and migration in human gastric cancer through upregulation of thrombospondin-1. Int J Oncol. 2017;50(5):1501–1512. doi:10.3892/ijo.2017.392728339036
   PubMed Web of Science ®Google Scholar
• Katoh M, Nakagama H. FGF receptors: cancer biology and therapeutics. Med Res Rev. 2014;34(2):280–300. doi:10.1002/med.2128823696246
   PubMed Web of Science ®Google Scholar
• Inan S, Hayran M. Cell signaling pathways related to epithelial mesenchymal transition in cancer metastasis. Crit Rev Oncog. 2019;24(1):47–54. doi:10.1615/CritRevOncog.201802950931679219
   PubMedGoogle Scholar
• Ma HW, Xi DY, Ma JZ, et al. Long noncoding RNA AFAP1-AS1 promotes cell proliferation and metastasis via the miR-155-5p/FGF7 axis and predicts poor prognosis in gastric cancer. Dis Markers. 2020;2020:8140989. doi:10.1155/2020/814098932051698
   PubMed Web of Science ®Google Scholar