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Original Research

microRNA-145-5p Inhibits Migration, Invasion, and Metastasis in Hepatocellular Carcinoma by Inhibiting ARF6

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Pages 3473-3484 | Published online: 21 Apr 2021

References

  • Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424. doi:10.3322/caac.2149230207593
  • Yu J, Xu QG, Wang ZG, et al. Circular RNA cSMARCA5 inhibits growth and metastasis in hepatocellular carcinoma. J Hepatol. 2018;68(6):1214–1227. doi:10.1016/j.jhep.2018.01.01229378234
  • Fang JH, Zhou HC, Zhang C, et al. A novel vascular pattern promotes metastasis of hepatocellular carcinoma in an epithelial-mesenchymal transition-independent manner. Hepatology. 2015;62(2):452–465. doi:10.1002/hep.2776025711742
  • Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell. 2009;136(2):215–233. doi:10.1016/j.cell.2009.01.00219167326
  • He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet. 2004;5(7):522–531. doi:10.1038/nrg137915211354
  • Garzon R, Calin GA, Croce CM. MicroRNAs in Cancer. Annu Rev Med. 2009;60:167–179. doi:10.1146/annurev.med.59.053006.10470719630570
  • Ishii H, Vodnala SK, Achyut BR, et al. miR-130a and miR-145 reprogram Gr-1CD11b myeloid cells and inhibit tumor metastasis through improved host immunity. Nat Commun. 2018;9(1):2611. doi:10.1038/s41467-018-05023-929973593
  • Wong QW, Lung RW, Law PT, et al. MicroRNA-223 is commonly repressed in hepatocellular carcinoma and potentiates expression of Stathmin1. Gastroenterology. 2008;135(1):257–269. doi:10.1053/j.gastro.2008.04.00318555017
  • Gai X, Tang B, Liu F, et al. mTOR/miR-145-regulated exosomal GOLM1 promotes hepatocellular carcinoma through augmented GSK-3β/MMPs. J Genet Genomics. 2019;46(5):235–245. doi:10.1016/j.jgg.2019.03.01331186161
  • D’Souza-Schorey C, Chavrier P. ARF proteins: roles in membrane traffic and beyond. Nat Rev Mol Cell Biol. 2006;7(5):347–358. doi:10.1038/nrm191016633337
  • Donaldson JG. Multiple roles for Arf6: sorting, structuring, and signaling at the plasma membrane. J Biol Chem. 2003;278(43):41573–41576. doi:10.1074/jbc.R30002620012912991
  • Hashimoto S, Furukawa S, Hashimoto A, et al. KRASARF6 and AMAP1 are major targets of and mutations to promote invasion, PD-L1 dynamics, and immune evasion of pancreatic cancer. Proc Natl Acad Sci USA. 2019;116(35):17450–17459. doi:10.1073/pnas.190176511631399545
  • Gao W, Zhang C, Li W, et al. Promoter Methylation-Regulated miR-145-5p Inhibits Laryngeal Squamous Cell Carcinoma Progression by Targeting FSCN1. Mol Ther. 2019;27(2):365–379. doi:10.1016/j.ymthe.2018.09.01830341010
  • Qi S, Su L, Li J, et al. Arf6-driven endocytic recycling of CD147 determines HCC malignant phenotypes. J Exp Clin Cancer Res. 2019;38(1):471. doi:10.1186/s13046-019-1464-931752956
  • Onodera Y, Nam JM, Hashimoto A, et al. Rab5c promotes AMAP1-PRKD2 complex formation to enhance β1 integrin recycling in EGF-induced cancer invasion. J Cell Biol. 2012;197(7):983–996. doi:10.1083/jcb.20120106522734003
  • Sato H, Hatanaka KC, Hatanaka Y, et al. High level expression of AMAP1 protein correlates with poor prognosis and survival after surgery of head and neck squamous cell carcinoma patients. Cell Commun Signal. 2014;12(1):17. doi:10.1186/1478-811X-12-1724621372
  • Li M, Wang J, Ng SS, et al. Adenosine diphosphate-ribosylation factor 6 is required for epidermal growth factor-induced glioblastoma cell proliferation. Cancer. 2009;115(21):4959–4972. doi:10.1002/cncr.2455019642173
  • Forner A, Reig M, Bruix J. Reig M and Bruix J. Hepatocellular carcinoma. Lancet. 2018;391(10127):1301–1314. doi:10.1016/S0140-6736(18)30010-229307467
  • Lu M, Zhu WW, Wang X, et al. ACOT12-Dependent Alteration of Acetyl-CoA Drives Hepatocellular Carcinoma Metastasis by Epigenetic Induction of Epithelial-Mesenchymal Transition. Cell Metab. 2019;29(4):886–900. doi:10.1016/j.cmet.2018.12.01930661930
  • Lupini L, Pepe F, Ferracin M, et al. Over-expression of the miR-483-3p Overcomes the miR-145/TP53 Pro-apoptotic Loop in Hepatocellular Carcinoma. Oncotarget. 2016;7(21):31361–31371. doi:10.18632/oncotarget.891327120784
  • Wei F, Ma C, Zhou T, et al. Exosomes derived from gemcitabine-resistant cells transfer malignant phenotypic traits via delivery of miRNA-222-3p. Mol cancer. 2017;16(1):132. doi:10.1186/s12943-017-0694-828743280
  • Yu L, Wang S, Lin X, Lu Y, Gu P. MicroRNA-124a inhibits cell proliferation and migration in liver cancer by regulating interleukin-11. Mol Med Rep. 2018;17(3):3972–3978. doi:10.3892/mmr.2017.834829286137
  • Wang B, Dong W, Li X. miR-145-5p Acts as a Novel Tumor Suppressor in Hepatocellular Carcinoma Through Targeting RAB18. Technol Cancer Res Treat. 2019;18:1533033819850189. doi:10.1177/153303381985018931106707
  • Hernández-Deviez DJ, Casanova JE, Wilson JM. Regulation of dendritic development by the ARF exchange factor ARNO. Nat Neurosci. 2002;5(7):623–624. doi:10.1038/nn86512032543
  • Wu B, Wang Y, Yang XM, et al. Basigin-mediated redistribution of CD98 promotes cell spreading and tumorigenicity in hepatocellular carcinoma. J Exp Clin Cancer Res. 2015;34:110. doi:10.1186/s13046-015-0226-626437640
  • Hsu WC, Li WM, Lee YC, et al. MicroRNA-145 Suppresses Cell Migration and Invasion in Upper Tract Urothelial Carcinoma by Targeting ARF6. FASEB J. 2020;34(4):5975–5992. doi:10.1096/fj.201902555R32077148
  • Dong G, Zhang S, Shen S, et al. SPATS2, negatively regulated by miR-145-5p, promotes hepatocellular carcinoma progression through regulating cell cycle. Cell Death Dis. 2020;11(10):837. doi:10.1038/s41419-020-03039-y33037180
  • Zhou J, Zhang X, Li W, Chen Y. MicroRNA-145-5p regulates the proliferation of epithelial ovarian cancer cells via targeting SMAD4. J Ovarian Res. 2020;13(1):54. doi:10.1186/s13048-020-00656-132366274