68
Views
1
CrossRef citations to date
0
Altmetric
Original Research

Efficacy and Safety of Transarterial Chemoembolization for the Treatment of Unresectable Hepatocellular Carcinoma Associated with Bile Duct Tumor Thrombus: A Real-World Retrospective Cohort Study

, , , , , , , & show all
Pages 3551-3560 | Published online: 28 Apr 2021

References

  • Bray F , Ferlay J , Soerjomataram I , Siegel RL , Torre LA , Jemal A . Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin . 2018;68(6):394–424. doi:10.3322/caac.21492 30207593
  • Chen W , Zheng R , Baade PD , et al. Cancer statistics in China, 2015. CA Cancer J Clin . 2016;66(2):115–132. doi:10.3322/caac.21338 26808342
  • Lee JW , Han JK , Kim TK , et al. Obstructive jaundice in hepatocellular carcinoma: response after percutaneous transhepatic biliary drainage and prognostic factors. Cardiovasc Intervent Radiol . 2002;25(3):176–179. doi:10.1007/s00270-001-0100-0 12058212
  • Kim DS , Kim BW , Hatano E , et al. Surgical outcomes of hepatocellular carcinoma with bile duct tumor thrombus: a Korea-Japan multicenter study. Ann Surg . 2020;271(5):913–921. doi:10.1097/SLA.0000000000003014 30216223
  • Lu WP , Tang HW , Yang ZY , Jiang K , Chen YL , Lu SC . A proposed modification for the Barcelona clinic liver cancer staging system: adding bile duct tumor thrombus status in patients with hepatocellular carcinoma. Am J Surg . 2020;220(4):965–971. doi:10.1016/j.amjsurg.2020.04.003 32336518
  • Sun J , Wu J , Shi J , et al. Thrombus-first surgery for hepatocellular carcinoma with bile duct tumor thrombus. J Gastrointest Surg . 2020. doi:10.1007/s11605-020-04813-1
  • An J , Lee KS , Kim KM , et al. Clinical features and outcomes of patients with hepatocellular carcinoma complicated with bile duct invasion. Clin Mol Hepatol . 2017;23(2):160–169. doi:10.3350/cmh.2016.0088 28506055
  • Oba A , Takahashi S , Kato Y , et al. Usefulness of resection for hepatocellular carcinoma with macroscopic bile duct tumor thrombus. Anticancer Res . 2014;34(8):4367–4372.25075073
  • Satoh S , Ikai I , Honda G , et al. Clinicopathologic evaluation of hepatocellular carcinoma with bile duct thrombi. Surgery . 2000;128(5):779–783. doi:10.1067/msy.2000.108659 11056440
  • Shiomi M , Kamiya J , Nagino M , et al. Hepatocellular carcinoma with biliary tumor thrombi: aggressive operative approach after appropriate preoperative management. Surgery . 2001;129(6):692–698. doi:10.1067/msy.2001.113889 11391367
  • Wong TC , Cheung TT , Chok KS , et al. Outcomes of hepatectomy for hepatocellular carcinoma with bile duct tumour thrombus. HPB . 2015;17(5):401–408. doi:10.1111/hpb.12368 25410794
  • European Association for the Study of the Liver . EASL clinical practice guidelines: management of hepatocellular carcinoma. J Hepatol . 2018;69(1):182–236. doi:10.1016/j.jhep.2018.03.019 29628281
  • Heimbach JK , Kulik LM , Finn RS , et al. AASLD guidelines for the treatment of hepatocellular carcinoma. Hepatology . 2018;67(1):358–380. doi:10.1002/hep.29086 28130846
  • Lin S , Hoffmann K , Schemmer P . Treatment of hepatocellular carcinoma: a systematic review. Liver Cancer . 2012;1(3–4):144–158. doi:10.1159/000343828 24159579
  • Gui CH , Baey S , D’cruz RT , Shelat VG . Trans-arterial chemoembolization + radiofrequency ablation versus surgical resection in hepatocellular carcinoma - a meta-analysis. Eur J Surg Oncol . 2020;46(5):763–771. doi:10.1016/j.ejso.2020.01.004 31937433
  • Dai QS , Gu HL , Ye S , et al. Transarterial chemoembolization vs. conservative treatment for unresectable infiltrating hepatocellular carcinoma: a retrospective comparative study. Mol Clin Oncol . 2014;2(6):1047–1054. doi:10.3892/mco.2014.391 25279196
  • Lee IC , Huo TI , Huang YH , et al. Transarterial chemoembolization can prolong survival for patients with metastatic hepatocellular carcinoma: a propensity score matching analysis. Hepatol Int . 2012;6(4):753–762. doi:10.1007/s12072-011-9322-7 26201524
  • Kong JY , Li SM , Fan HY , Zhang L , Zhao HJ , Li SM . Transarterial chemoembolization extends long-term survival in patients with unresectable hepatocellular carcinoma. Medicine . 2018;97(33):e11872. doi:10.1097/MD.0000000000011872 30113483
  • Zhou J , Sun H , Wang Z , et al. Guidelines for the diagnosis and treatment of hepatocellular carcinoma (2019 edition). Liver Cancer . 2020;9(6):682–720. doi:10.1159/000509424 33442540
  • Jung AY , Lee JM , Choi SH , et al. CT features of an intraductal polypoid mass: differentiation between hepatocellular carcinoma with bile duct tumor invasion and intraductal papillary cholangiocarcinoma. J Comput Assist Tomogr . 2006;30(2):173–181. doi:10.1097/00004728-200603000-00002 16628028
  • Choi J , Ryu JK , Lee SH , et al. Palliative treatment of unresectable hepatocellular carcinoma with obstructive jaundice using biliary drainage with subsequent transarterial chemoembolization. J Palliat Med . 2013;16(9):1026–1033. doi:10.1089/jpm.2013.0067 23888306
  • Sun JJ , Wang K , Zhang CZ , et al. Postoperative adjuvant transcatheter arterial chemoembolization after R0 hepatectomy improves outcomes of patients who have hepatocellular carcinoma with microvascular invasion. Ann Surg Oncol . 2016;23(4):1344–1351. doi:10.1245/s10434-015-5008-z 26714945
  • Chen ZH , Zhang XP , Wang K , et al. Liver resection versus transcatheter arterial chemoembolization for the treatment of patients with hepatocellular carcinoma and hepatic vein or inferior vena cava tumor thrombus: a propensity score matching analysis. Hepatol Res . 2019;49(4):441–452. doi:10.1111/hepr.13297 30549370
  • Ikenaga N , Chijiiwa K , Otani K , Ohuchida J , Uchiyama S , Kondo K . Clinicopathologic characteristics of hepatocellular carcinoma with bile duct invasion. J Gastrointest Surg . 2009;13(3):492–497. doi:10.1007/s11605-008-0751-0 19011945
  • Noda T , Nagano H , Tomimaru Y , et al. Prognosis of hepatocellular carcinoma with biliary tumor thrombi after liver surgery. Surgery . 2011;149(3):371–377. doi:10.1016/j.surg.2010.08.006 20869094
  • Wang DD , Wu LQ , Wang ZS . Prognosis of hepatocellular carcinoma with bile duct tumor thrombus after R0 resection: a matched study. Hepatobiliary Pancreat Dis Int . 2016;15(6):626–632. doi:10.1016/s1499-3872(16)60143-1 27919852
  • Yu XH , Xu LB , Liu C , Zhang R , Wang J . Clinicopathological characteristics of 20 cases of hepatocellular carcinoma with bile duct tumor thrombi. Dig Dis Sci . 2011;56(1):252–259. doi:10.1007/s10620-010-1256-8 20437099
  • Choi JW , Chung JW , Cho YK , et al. Transarterial chemoembolization for hepatocellular carcinomas with central bile duct invasion: safety, prognosis, and predictive factors. Cardiovasc Intervent Radiol . 2015;38(4):937–945. doi:10.1007/s00270-014-1032-9 25465065
  • Cui W , Xu R , Wang Y , Shi F , Li J , Chen X . Percutaneous endobiliary radiofrequency ablation and stents in management of hepatocellular carcinoma with bile duct tumor thrombus: initial single-institution experience. Asia Pac J Clin Oncol . 2020;16(4):259–265. doi:10.1111/ajco.13330 32368843
  • Ahmed S , de Souza NN , Qiao W , Kasai M , Keem LJ , Shelat VG . Quality of life in hepatocellular carcinoma patients treated with transarterial chemoembolization. HPB Surg . 2016;2016:6120143. doi:10.1155/2016/6120143 27143815
  • Salem R , Lewandowski RJ , Mulcahy MF , et al. Radioembolization for hepatocellular carcinoma using Yttrium-90 microspheres: a comprehensive report of long-term outcomes. Gastroenterology . 2010;138(1):52–64. doi:10.1053/j.gastro.2009.09.006 19766639
  • Spreafico C , Sposito C , Vaiani M , et al. Development of a prognostic score to predict response to Yttrium-90 radioembolization for hepatocellular carcinoma with portal vein invasion. J Hepatol . 2018;68(4):724–732. doi:10.1016/j.jhep.2017.12.026 29331342
  • Llovet JM , Real MI , Montaña X , et al. Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial. Lancet . 2002;359(9319):1734–1739. doi:10.1016/S0140-6736(02)08649-X 12049862
  • Lo CM , Ngan H , Tso WK , et al. Randomized controlled trial of transarterial lipiodol chemoembolization for unresectable hepatocellular carcinoma. Hepatology . 2002;35(5):1164–1171. doi:10.1053/jhep.2002.33156 11981766
  • Luo J , Guo RP , Lai EC , et al. Transarterial chemoembolization for unresectable hepatocellular carcinoma with portal vein tumor thrombosis: a prospective comparative study. Ann Surg Oncol . 2011;18(2):413–420. doi:10.1245/s10434-010-1321-8 20839057
  • Niu ZJ , Ma YL , Kang P , et al. Transarterial chemoembolization compared with conservative treatment for advanced hepatocellular carcinoma with portal vein tumor thrombus: using a new classification. Med Oncol . 2012;29(4):2992–2997. doi:10.1007/s12032-011-0145-0 22200992
  • Chung GE , Lee JH , Kim HY , et al. Transarterial chemoembolization can be safely performed in patients with hepatocellular carcinoma invading the main portal vein and may improve the overall survival. Radiology . 2011;258(2):627–634. doi:10.1148/radiol.10101058 21273524
  • Xiang X , Lau WY , Wu ZY , et al. Transarterial chemoembolization versus best supportive care for patients with hepatocellular carcinoma with portal vein tumor thrombus: a multicenter study. Eur J Surg Oncol . 2019;45(8):1460–1467. doi:10.1016/j.ejso.2019.03.042 31005471