115
Views
16
CrossRef citations to date
0
Altmetric
Original Research

Silencing of circHIPK3 Sensitizes Paclitaxel-Resistant Breast Cancer Cells to Chemotherapy by Regulating HK2 Through Targeting miR-1286

, , &
Pages 5573-5585 | Published online: 12 Jul 2021

References

  • Bray F , Ferlay J , Soerjomataram I , et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin . 2018;68(6):394–424. doi:10.3322/caac.21492 30207593
  • Ghersi D , Willson ML , Chan MM , et al. Taxane-containing regimens for metastatic breast cancer. Cochrane Database Syst Rev . 2015;2015:Cd003366. doi:10.1002/14651858.CD003366.pub3
  • Megerdichian C , Olimpiadi Y , Hurvitz SA . nab-Paclitaxel in combination with biologically targeted agents for early and metastatic breast cancer. Cancer Treat Rev . 2014;40(5):614–625. doi:10.1016/j.ctrv.2014.02.001 24560997
  • Yardley DA . Drug resistance and the role of combination chemotherapy in improving patient outcomes. Int J Breast Cancer . 2013;2013:137414. doi:10.1155/2013/137414 23864953
  • Szabo L , Salzman J . Detecting circular RNAs: bioinformatic and experimental challenges. Nat Rev Genet . 2016;17(11):679–692. doi:10.1038/nrg.2016.114 27739534
  • Anastasiadou E , Jacob LS , Slack FJ . Non-coding RNA networks in cancer. Nat Rev Cancer . 2018;18(1):5–18. doi:10.1038/nrc.2017.99 29170536
  • Gao D , Zhang X , Liu B , et al. Screening circular RNA related to chemotherapeutic resistance in breast cancer. Epigenomics . 2017;9(9):1175–1188. doi:10.2217/epi-2017-0055 28803498
  • Dou D , Ren X , Han M , et al. CircUBE2D2 (hsa_circ_0005728) promotes cell proliferation, metastasis and chemoresistance in triple-negative breast cancer by regulating miR-512-3p/CDCA3 axis. Cancer Cell Int . 2020;20(1):454. doi:10.1186/s12935-020-01547-7 32944002
  • Zang H , Li Y , Zhang X , et al. Circ-RNF111 contributes to paclitaxel resistance in breast cancer by elevating E2F3 expression via miR-140-5p. Thorac Cancer . 2020;11(7):1891–1903. doi:10.1111/1759-7714.13475 32445273
  • Zhang Y , Liu Q , Liao Q . CircHIPK3: a promising cancer-related circular RNA. Am J Transl Res . 2020;12(10):6694–6704.33194066
  • Chen ZG , Zhao HJ , Lin L , et al. Circular RNA CirCHIPK3 promotes cell proliferation and invasion of breast cancer by sponging miR-193a/HMGB1/PI3K/AKT axis. Thorac Cancer . 2020;11(9):2660–2671. doi:10.1111/1759-7714.13603 32767499
  • Liu Y , Xia L , Dong L , et al. CircHIPK3 promotes gemcitabine (GEM) resistance in pancreatic cancer cells by sponging miR-330-5p and targets RASSF1. Cancer Manag Res . 2020;12:921–929. doi:10.2147/cmar.s239326 32104074
  • Zhang Y , Li C , Liu X , et al. circHIPK3 promotes oxaliplatin-resistance in colorectal cancer through autophagy by sponging miR-637. EBioMedicine . 2019;48:277–288. doi:10.1016/j.ebiom.2019.09.051 31631038
  • Wang YW , Zhang W , Ma R . Bioinformatic identification of chemoresistance-associated microRNAs in breast cancer based on microarray data. Oncol Rep . 2018;39(3):1003–1010. doi:10.3892/or.2018.6205 29328395
  • Wang J , Yang M , Li Y , et al. The role of microRNAs in the chemoresistance of breast cancer. Drug Dev Res . 2015;76(7):368–374. doi:10.1002/ddr.21275 26310899
  • Lee JW , Guan W , Han S , et al. MicroRNA-708-3p mediates metastasis and chemoresistance through inhibition of epithelial-to-mesenchymal transition in breast cancer. Cancer Sci . 2018;109(5):1404–1413. doi:10.1111/cas.13588 29575368
  • Hong T , Ding J , Li W . miR-7 reverses breast cancer resistance to chemotherapy by targeting MRP1 and BCL2. Onco Targets Ther . 2019;12:11097–11105. doi:10.2147/ott.s213780 31908478
  • Santos JC , Lima NDS , Sarian LO , et al. Exosome-mediated breast cancer chemoresistance via miR-155 transfer. Sci Rep . 2018;8(1):829. doi:10.1038/s41598-018-19339-5 29339789
  • Yang S , Chen M , Lin CA . Novel lncRNA MYOSLID/miR-1286/RAB13 axis plays a critical role in osteosarcoma progression. Cancer Manag Res . 2019;11:10345–10351. doi:10.2147/cmar.s231376 31849524
  • Patra KC , Wang Q , Bhaskar PT , et al. Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer. Cancer Cell . 2013;24(2):213–228. doi:10.1016/j.ccr.2013.06.014 23911236
  • Lis P , Dyląg M , Niedźwiecka K , et al. The HK2 dependent “Warburg Effect” and mitochondrial oxidative phosphorylation in cancer: targets for effective therapy with 3-bromopyruvate. Molecules . 2016;21(12):1730. doi:10.3390/molecules21121730
  • Gao Y , Yang Y , Yuan F , et al. TNFα-YAP/p65-HK2 axis mediates breast cancer cell migration. Oncogenesis . 2017;6(9):e383. doi:10.1038/oncsis.2017.83 28945218
  • Zhang T , Zhu X , Wu H , et al. Targeting the ROS/PI3K/AKT/HIF-1α/HK2 axis of breast cancer cells: combined administration of Polydatin and 2-Deoxy-d-glucose. J Cell Mol Med . 2019;23(5):3711–3723. doi:10.1111/jcmm.14276 30920152
  • Lee HJ , Li CF , Ruan D , et al. Non-proteolytic ubiquitination of Hexokinase 2 by HectH9 controls tumor metabolism and cancer stem cell expansion. Nat Commun . 2019;10(1):2625. doi:10.1038/s41467-019-10374-y 31201299
  • He R , Liu H . TRIM59 knockdown blocks cisplatin resistance in A549/DDP cells through regulating PTEN/AKT/HK2. Gene . 2020;747:144553. doi:10.1016/j.gene.2020.144553 32165307
  • Wróbel AM , Gregoraszczuk E . Differential effect of methyl-, butyl- and propylparaben and 17β-estradiol on selected cell cycle and apoptosis gene and protein expression in MCF-7 breast cancer cells and MCF-10A non-malignant cells. J Appl Toxicol . 2014;34(9):1041–1050. doi:10.1002/jat.2978 24481588
  • Yang W , Gong P , Yang Y , et al. Circ-ABCB10 contributes to paclitaxel resistance in breast cancer through let-7a-5p/DUSP7 axis. Cancer Manag Res . 2020;12:2327–2337. doi:10.2147/cmar.s238513 32273769
  • Hatley ME , Patrick DM , Garcia MR , et al. Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21. Cancer Cell . 2010;18(3):282–293. doi:10.1016/j.ccr.2010.08.013 20832755
  • Liu G , Zhang Z , Song Q , et al. Circ_0006528 contributes to paclitaxel resistance of breast cancer cells by regulating miR-1299/CDK8 axis. Onco Targets Ther . 2020;13:9497–9511. doi:10.2147/ott.s252886 33061434
  • Chu A , Liu J , Yuan Y , et al. Comprehensive analysis of aberrantly expressed ceRNA network in gastric cancer with and without H.pylori infection. J Cancer . 2019;10(4):853–863. doi:10.7150/jca.27803 30854091
  • Yao T , Rao Q , Liu L , et al. Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in cervical cancer. Virol J . 2013;10(1):175. doi:10.1186/1743-422x-10-175 23732000
  • Zhang KQ , Chu XD . GANT61 plays antitumor effects by inducing oxidative stress through the miRNA-1286/RAB31 axis in osteosarcoma. Cell Biol Int . 2020;45(1):61–73. doi:10.1002/cbin.11467 32936498
  • Wei X , Gu X , Ma M , et al. Long noncoding RNA HCP5 suppresses skin cutaneous melanoma development by regulating RARRES3 gene expression via sponging miR-12. Onco Targets Ther . 2019;12:6323–6335. doi:10.2147/ott.s195796 31496735
  • Gao YW , Ma F , Xie YC , et al. Sp1-induced upregulation of the long noncoding RNA TINCR inhibits cell migration and invasion by regulating miR-107/miR-1286 in lung adenocarcinoma. Am J Transl Res . 2019;11(8):4761–4775.31497197
  • Hummel R , Wang T , Watson DI , et al. Chemotherapy-induced modification of microRNA expression in esophageal cancer. Oncol Rep . 2011;26(4):1011–1017. doi:10.3892/or.2011.1381 21743970
  • Garcia SN , Guedes RC , Marques MM . Unlocking the potential of HK2 in cancer metabolism and therapeutics. Curr Med Chem . 2019;26:7285–7322. doi:10.2174/0929867326666181213092652 30543165
  • Guo Y , Liang F , Zhao F , et al. Resibufogenin suppresses tumor growth and Warburg effect through regulating miR-143-3p/HK2 axis in breast cancer. Mol Cell Biochem . 2020;466(1–2):103–115. doi:10.1007/s11010-020-03692-z 32006291
  • Akram M . Mini-review on glycolysis and cancer. J Cancer Educ . 2013;28(3):454–457. doi:10.1007/s13187-013-0486-9 23728993