Advanced search
Publication Cover
Cancer Management and Research Volume 13, 2021 - Issue
Submit an article Journal homepage
117
Views
5
CrossRef citations to date
0
Altmetric
Original Research

Treatment and Prognosis of Solid and Cystic Brain Metastases in Patients with Non-Small-Cell Lung Cancer

Yi-Bing Xu1 Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, 310022, People’s Republic of China;2 Institute of Cancer and Basic Medicine (IBMC), Chinese Academy of Sciences, Hangzhou, 310022, People’s Republic of China
,
Yiping Zhang1 Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, 310022, People’s Republic of China;2 Institute of Cancer and Basic Medicine (IBMC), Chinese Academy of Sciences, Hangzhou, 310022, People’s Republic of China
,
Zhengbo Song1 Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, 310022, People’s Republic of China;2 Institute of Cancer and Basic Medicine (IBMC), Chinese Academy of Sciences, Hangzhou, 310022, People’s Republic of China
,
Wenxian Wang1 Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, 310022, People’s Republic of China;2 Institute of Cancer and Basic Medicine (IBMC), Chinese Academy of Sciences, Hangzhou, 310022, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-3047-4149
ORCID Icon &
Lan Shao1 Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, 310022, People’s Republic of China;2 Institute of Cancer and Basic Medicine (IBMC), Chinese Academy of Sciences, Hangzhou, 310022, People’s Republic of ChinaCorrespondence[email protected]
Pages 6309-6317 | Published online: 10 Aug 2021

References

  • SiegelRL, MillerKD, JemalA. Cancer statistics, 2017. CA Cancer J Clin. 2017;67:7–30. doi:10.3322/caac.2138728055103
  • NussbaumES, DjalilianHR, ChoKH, HallWA. Brain metastases. histology, multiplicity, surgery, and survival. Cancer. 1996;78:1781–1788. doi:10.1002/(SICI)1097-0142(19961015)78:8<1781::AID-CNCR19>3.0.CO;2-U8859192
  • ShiY, SunY, YuJ, et al. [China experts consensus on the diagnosis and treatment of brain metastases of lung cancer (2017 version)]. Zhongguo Fei Ai Za Zhi. 2017;20:1–13. [Chinese].28103967
  • LombardiG, Di StefanoAL, FarinaP, et al. Systemic treatments for brain metastases from breast cancer, non-small cell lung cancer, melanoma and renal cell carcinoma: an overview of the literature. Cancer Treat Rev. 2014;40:951–959. doi:10.1016/j.ctrv.2014.05.00724909312
  • OwonikokoTK, ArbiserJ, ZelnakA, et al. Current approaches to the treatment of metastatic brain tumours. Nat Rev Clin Oncol. 2014;11:203–222. doi:10.1038/nrclinonc.2014.2524569448
  • MehtaMP, RodrigusP, TerhaardCH, et al. Survival and neurologic outcomes in a randomized trial of motexafin gadolinium and whole brain radiation therapy in brain metastases. J Clin Oncol. 2003;21:2529–2536. doi:10.1200/JCO.2003.12.12212829672
  • BulbulA, FordePM, MurtuzaA, et al. Systemic treatment options for brain metastases from non-small-cell lung cancer. Oncology. 2018;32:156–163.29684234
  • LimSH, LeeJY, LeeMY, et al. A randomized Phase III trial of stereotactic radiosurgery (SRS) versus observation for patients with asymptomatic cerebral oligo-metastases in non-small-cell lung cancer. Ann Oncol. 2015;26(4):762–768. doi:10.1093/annonc/mdu58425538174
  • UchinoM, NagaoT, SeikiY, et al. Radiosurgery for cystic metastatic brain tumor. No Shinkei Geka. 2000;28:417–421.10806624
  • GardnerWJ, CollisJS, LewisLA. Cystic brain tumors and the blood-brain barrier. Comparison of protein fractions in cyst fluids and sera. Arch Neurol. 1963;8:291–298. doi:10.1001/archneur.1963.0046003007500713946556
  • SunB, HuangZ, WuS, et al. Cystic brain metastasis is associated with poor prognosis in patients with advanced breast cancer. Oncotarget. 2016;7:74006–74014. doi:10.18632/oncotarget.1217627659537
  • SekineA, KatoT, HagiwaraE, et al. Metastatic brain tumors from non-small cell lung cancer with EGFR mutations: distinguishing influence of exon 19 deletion on radiographic features. Lung Cancer. 2012;77:64–69. doi:10.1016/j.lungcan.2011.12.01722335887
  • ShinDY, NaII, KimCH, et al. EGFR mutation and brain metastasis in pulmonary adenocarcinomas. J Thorac Oncol. 2014;9:195–199. doi:10.1097/JTO.000000000000006924419416
  • RusthovenCG, DoebeleRC. Management of brain metastases in ALK-positive non-small-cell lung cancer. J Clin Oncol. 2016;34:2814–2819. doi:10.1200/JCO.2016.67.241027298405
  • GrubbWR, MachtayM, DowlatiA, BiswasT. Diffuse atypical cystic brain metastases in ALK+ NSCLC treated with whole brain radiation and second-generation ALK-targeted therapy. Pract Radiat Oncol. 2019;9:e129–e133. doi:10.1016/j.prro.2018.11.00230665865
  • MartaGN, da Cunha Colombo BonadioRR, MartinsRE, et al. Cystic brain metastases in ALK-rearranged non-small cell lung cancer. Ecancermedicalscience. 2018;12:818.
  • KimSH, HyunJW, KimHJ, et al. De novo cystic brain lesions mimicking neurocysticercosis in ALK-positive lung cancer. Lung Cancer. 2017;110:53–55. doi:10.1016/j.lungcan.2017.06.00328676219
  • SaraceniC, LiPM, GainorJF, et al. Cystic brain metastases in NSCLC harboring the EML4-ALK translocation after treatment with crizotinib. J Thorac Oncol. 2015;10:1116–1117. doi:10.1097/JTO.000000000000040926134230
  • NarayananV, HonceMJ, MehrotraS, CamidgeDR. Cystic brain metastases occurring in anaplastic lymphoma kinase gene rearranged non-small-cell lung cancer patients receiving crizotinib. Clin Lung Cancer. 2016;17:85–90. doi:10.1016/j.cllc.2015.07.00326314227
  • HayashiH, OkamotoI, TanizakiJ, et al. Cystic brain metastasis in non-small-cell lung cancer with ALK rearrangement. J Clin Oncol. 2014;32:e122–e124. doi:10.1200/JCO.2012.48.214124567432
  • ZeeYK, ChinTM, WongAS. Fatal cystic change of brain metastasis after response to gefitinib in non-small-cell lung cancer. J Clin Oncol. 2009;27:e145–146. doi:10.1200/JCO.2009.22.450119667265
  • BrigellRH, CagneyDN, MartinAM, et al. Local control after brain-directed radiation in patients with cystic versus solid brain metastases. J Neurooncol. 2019;142(2):355–363. doi:10.1007/s11060-019-03106-130715665
  • WangH, LiuX, JiangX, et al. Cystic brain metastases had slower speed of tumor shrinkage but similar prognosis compared with solid tumors that underwent radiosurgery treatment. Cancer Manag Res. 2019;11:1753–1763. doi:10.2147/CMAR.S18867430858728

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.