117
Views
10
CrossRef citations to date
0
Altmetric
Original Research

Weight Loss Improves Pregnancy and Livebirth Outcomes in Young Women with Early-Stage Endometrial Cancer and Atypical Hyperplasia

, , , , , , , , ORCID Icon, & show all
Pages 5711-5722 | Published online: 14 Jul 2021

References

  • Koh WJ, Abu-Rustum NR, Bean S, et al. Uterine Neoplasms, Version 1.2018, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2018;16(2):170–199. doi:10.6004/jnccn.2018.000629439178
  • Lortet-Tieulent J, Ferlay J, Bray F, Jemal A. International patterns and trends in endometrial cancer incidence, 1978–2013. J Natl Cancer Inst. 2018;110(4):354–361. doi:10.1093/jnci/djx21429045681
  • Shaw E, Farris M, McNeil J, Friedenreich C. Obesity and endometrial cancer. Recent Results Cancer Res. 2016;208:107–136.27909905
  • Terzic M, Norton M, Terzic S, Bapayeva G, Aimagambetova G. Fertility preservation in endometrial cancer patients: options, challenges and perspectives. Ecancermedicalscience. 2020;14:1030. doi:10.3332/ecancer.2020.103032419842
  • Casadio P, La Rosa M, Alletto A, et al. Fertility sparing treatment of endometrial cancer with and without initial infiltration of myometrium: a single center experience. Cancers. 2020;12(12):3571. doi:10.3390/cancers12123571
  • Soliman PT, Oh JC, Schmeler KM, et al. Risk factors for young premenopausal women with endometrial cancer. Obstet Gynecol. 2005;105(3):575–580. doi:10.1097/01.AOG.0000154151.14516.f715738027
  • Gallos ID, Yap J, Rajkhowa M, Luesley DM, Coomarasamy A, Gupta JK. Regression, relapse, and live birth rates with fertility-sparing therapy for endometrial cancer and atypical complex endometrial hyperplasia: a systematic review and metaanalysis. Am J Obstet Gynecol. 2012;207(4):266.e1–12. doi:10.1016/j.ajog.2012.08.011
  • Li M, Guo T, Cui R, Feng Y, Bai H, Zhang Z. Weight control is vital for patients with early-stage endometrial cancer or complex atypical hyperplasia who have received progestin therapy to spare fertility: a systematic review and meta-analysis. Cancer Manag Res. 2019;11:4005–4021. doi:10.2147/CMAR.S19460731190979
  • Giampaolino P, Di Spiezio Sardo A, Mollo A, et al. Hysteroscopic endometrial focal resection followed by levonorgestrel intrauterine device insertion as a fertility-sparing treatment of atypical endometrial hyperplasia and early endometrial cancer: a retrospective study. J Minim Invasive Gynecol. 2019;26(4):648–656. doi:10.1016/j.jmig.2018.07.00130017893
  • Mazzon I, Corrado G, Masciullo V, Morricone D, Ferrandina G, Scambia G. Conservative surgical management of stage IA endometrial carcinoma for fertility preservation. Fertil Steril. 2010;93(4):1286–1289. doi:10.1016/j.fertnstert.2008.12.00919700153
  • Yang B, Xu Y, Zhu Q, et al. Treatment efficiency of comprehensive hysteroscopic evaluation and lesion resection combined with progestin therapy in young women with endometrial atypical hyperplasia and endometrial cancer. Gynecol Oncol. 2019;153(1):55–62. doi:10.1016/j.ygyno.2019.01.01430674421
  • Best D, Avenell A, Bhattacharya S. How effective are weight-loss interventions for improving fertility in women and men who are overweight or obese? A systematic review and meta-analysis of the evidence. Hum Reprod Update. 2017;23(6):681–705. doi:10.1093/humupd/dmx02728961722
  • Wise MR, Jordan V, Lagas A, et al. Obesity and endometrial hyperplasia and cancer in premenopausal women: a systematic review. Am J Obstet Gynecol. 2016;214(6):689.e1–689.e17. doi:10.1016/j.ajog.2016.01.175
  • Silvestris E, de Pergola G, Rosania R, Loverro G. Obesity as disruptor of the female fertility. Reproductive Biol Endocrinol. 2018;16(1):22. doi:10.1186/s12958-018-0336-z
  • Park JY, Seong SJ, Kim TJ, Kim JW, Bae DS, Nam JH. Significance of body weight change during fertility-sparing progestin therapy in young women with early endometrial cancer. Gynecol Oncol. 2017;146(1):39–43. doi:10.1016/j.ygyno.2017.05.00228526167
  • Kiesel L, Eichbaum C, Baumeier A, Eichbaum M. Obesity epidemic - the underestimated risk of endometrial cancer. Cancers. 2020;12(12):3860. doi:10.3390/cancers12123860
  • Wei J, Zhang W, Feng L, Gao W. Comparison of fertility-sparing treatments in patients with early endometrial cancer and atypical complex hyperplasia: a meta-analysis and systematic review. Medicine. 2017;96(37):e8034. doi:10.1097/MD.000000000000803428906392
  • Cholakian D, Hacker K, Fader AN, Gehrig PA, Tanner EJ. Effect of oral versus intrauterine progestins on weight in women undergoing fertility preserving therapy for complex atypical hyperplasia or endometrial cancer. Gynecol Oncol. 2016;140(2):234–238. doi:10.1016/j.ygyno.2015.12.01026706662
  • Fink A, Cieslak S, Rosenbach F. Non-Pharmacological interventions for the prevention of weight gain in schizophrenic patients treated with antipsychotic medication. Psychiatr Prax. 2015;42(7):359–369. doi:10.1055/s-0035-155267026158719
  • Haggerty AF, Sarwer DB, Schmitz KH, Ko EM, Allison KC, Chu CS. Obesity and endometrial cancer: a lack of knowledge but opportunity for intervention. Nutr Cancer. 2017;69(7):990–995. doi:10.1080/01635581.2017.135931328937804
  • Yerevanian A, Soukas AA. Metformin: mechanisms in human obesity and weight loss. Curr Obes Rep. 2019;8(2):156–164. doi:10.1007/s13679-019-00335-330874963
  • Crosignani PG, Colombo M, Vegetti W, Somigliana E, Gessati A, Ragni G. Overweight and obese anovulatory patients with polycystic ovaries: parallel improvements in anthropometric indices, ovarian physiology and fertility rate induced by diet. Human Reproduction. 2003;18(9):1928–1932. doi:10.1093/humrep/deg36712923151
  • Cavalcante MB, Sarno M, Peixoto AB, Araujo Júnior E, Barini R. Obesity and recurrent miscarriage: a systematic review and meta-analysis. J Obstet Gynaecol Res. 2019;45(1):30–38. doi:10.1111/jog.1379930156037
  • Kawwass JF, Kulkarni AD, Hipp HS, Crawford S, Kissin DM, Jamieson DJ. Extremities of body mass index and their association with pregnancy outcomes in women undergoing in vitro fertilization in the United States. Fertil Steril. 2016;106(7):1742–1750. doi:10.1016/j.fertnstert.2016.08.02827666564
  • Boots C, Stephenson MD. Does obesity increase the risk of miscarriage in spontaneous conception: a systematic review. Semin Reprod Med. 2011;29(6):507–513. doi:10.1055/s-0031-129320422161463
  • Lowe MP, Cooper BC, Sood AK, Davis WA, Syrop CH, Sorosky JI. Implementation of assisted reproductive technologies following conservative management of FIGO grade I endometrial adenocarcinoma and/or complex hyperplasia with atypia. Gynecol Oncol. 2003;91(3):569–572. doi:10.1016/j.ygyno.2003.08.00714675678
  • Zhou R, Yang Y, Lu Q, et al. Prognostic factors of oncological and reproductive outcomes in fertility-sparing treatment of complex atypical hyperplasia and low-grade endometrial cancer using oral progestin in Chinese patients. Gynecol Oncol. 2015;139(3):424–428. doi:10.1016/j.ygyno.2015.09.07826428941
  • Bozdag G, Yarali H, Polat M, Esinler I, Tiras B, Ayhan A. ICSI outcome following conservative fertility sparing management of endometrial cancer. Reprod Biomed Online. 2009;18(3):416–420. doi:10.1016/S1472-6483(10)60102-219298743
  • Kim MJ, Choe SA, Kim MK, Yun BS, Seong SJ, Kim YS. Outcomes of in vitro fertilization cycles following fertility-sparing treatment in stage IA endometrial cancer. Arch Gynecol Obstet. 2019;300(4):975–980. doi:10.1007/s00404-019-05237-231440822
  • Zapardiel I, Cruz M, Diestro MD, Requena A, Garcia-Velasco JA. Assisted reproductive techniques after fertility-sparing treatments in gynaecological cancers. Hum Reprod Update. 2016;22(3):281–305. doi:10.1093/humupd/dmv06626759231
  • Travaglino A, Raffone A, Saccone G, et al. Immunohistochemical predictive markers of response to conservative treatment of endometrial hyperplasia and early endometrial cancer: a systematic review. Acta Obstet Gynecol Scand. 2019;98(9):1086–1099. doi:10.1111/aogs.1358730793281