Expression and Clinical Significance of the NCAPH, AGGF1, and FOXC2 Proteins in Serous Ovarian Cancer

References

• SungH, FerlayJ, SiegelRL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–249. doi:10.3322/caac.2166033538338
   PubMed Web of Science ®Google Scholar
• TorreLA, TrabertB, DeSantisCE, et al. Ovarian cancer statistics, 2018. CA Cancer J Clin. 2018;68(4):284–296. doi:10.3322/caac.2145629809280
   PubMed Web of Science ®Google Scholar
• De AndradeWP, Da Conceicao BragaL, GoncalesNG, et al. HSPA1A, HSPA1L and TRAP1 heat shock genes may be associated with prognosis in ovarian epithelial cancer. Oncol Lett. 2020;19(1):359–367. doi:10.3892/ol.2019.1109531897148
   PubMed Web of Science ®Google Scholar
• HiranoT. Condensins: universal organizers of chromosomes with diverse functions. Genes Dev. 2012;26(15):1659–1678. doi:10.1101/gad.194746.11222855829
   PubMed Web of Science ®Google Scholar
• WoodAJ, SeversonAF, MeyerBJ. Condensin and cohesin complexity: the expanding repertoire of functions. Nat Rev Genet. 2010;11(6):391–404. doi:10.1038/nrg279420442714
   PubMed Web of Science ®Google Scholar
• NeuwaldAF, HiranoT. HEAT repeats associated with condensins, cohesins, and other complexes involved in chromosome-related functions. Genome Res. 2000;10(10):1445–1452. doi:10.1101/gr.14740011042144
   PubMed Web of Science ®Google Scholar
• SunC, HuangS, WangH, et al. Non-SMC condensin I complex subunit H enhances proliferation, migration, and invasion of hepatocellular carcinoma. Mol Carcinog. 2019;58(12):2266–2275. doi:10.1002/mc.2311431523845
   PubMed Web of Science ®Google Scholar
• CuiF, HuJ, XuZ, TanJ, TangH. Overexpression of NCAPH is upregulated and predicts a poor prognosis in prostate cancer. Oncol Lett. 2019;17(6):5768–5776. doi:10.3892/ol.2019.1026031186803
   PubMed Web of Science ®Google Scholar
• YinL, JiangLP, ShenQS, et al. NCAPH plays important roles in human colon cancer. Cell Death Dis. 2017;8(3):e2680. doi:10.1038/cddis.2017.8828300828
   PubMed Web of Science ®Google Scholar
• TianXL, KadabaR, YouSA, et al. Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome. Nature. 2004;427(6975):640–645. doi:10.1038/nature0232014961121
   PubMed Web of Science ®Google Scholar
• YaoHH, WangBJ, WuY, et al. High expression of angiogenic factor with G-patch and FHA domain1 (AGGF1) predicts poor prognosis in gastric cancer. Med Sci Monit. 2017;23:1286–1294. doi:10.12659/msm.90324828289272
   PubMed Web of Science ®Google Scholar
• TuJ, YingX, ZhangD, et al. High expression of angiogenic factor AGGF1 is an independent prognostic factor for hepatocellular carcinoma. Oncotarget. 2017;8(67):111623. doi:10.18632/oncotarget.2288029340079
   PubMedGoogle Scholar
• ZhangX, SunH, ChenW, HeX. Elevated expression of AGGF1 predicts poor prognosis and promotes the metastasis of colorectal cancer. BMC Cancer. 2019;19(1):1252. doi:10.1186/s12885-019-6474-731881864
   PubMed Web of Science ®Google Scholar
• WangT, ZhengL, WangQ, et al. Emerging roles and mechanisms of FOXC2 in cancer. Clin Chim Acta. 2018;479:84–93. doi:10.1016/j.cca.2018.01.01929341903
   PubMed Web of Science ®Google Scholar
• RyuB, KimDS, DelucaAM, et al. Comprehensive expression profiling of tumor cell lines identifies molecular signatures of melanoma progression. PLoS One. 2007;2(7):e594. doi:10.1371/journal.pone.000059417611626
   PubMed Web of Science ®Google Scholar
• WangM, QiaoX, CooperT, et al. HPV E7-mediated NCAPH ectopic expression regulates the carcinogenesis of cervical carcinoma via PI3K/AKT/SGK pathway. Cell Death Dis. 2020;11(12):1049. doi:10.1038/s41419-020-03244-933311486
   PubMed Web of Science ®Google Scholar
• ShimomuraH, SasahiraT, NakashimaC, et al. Non-SMC condensin I complex subunit H (NCAPH) is associated with lymphangiogenesis and drug resistance in oral squamous cell carcinoma. J Clin Med. 2020;9(1):72. doi:10.3390/jcm9010072
   Web of Science ®Google Scholar
• ZhangT, YaoY, WangJ, et al. Haploinsufficiency of Klippel-Trenaunay syndrome gene Aggf1 inhibits developmental and pathological angiogenesis by inactivating PI3K and AKT and disrupts vascular integrity by activating VE-cadherin. Hum Mol Genet. 2016;25(23):5094–5110. doi:10.1093/hmg/ddw27327522498
   PubMed Web of Science ®Google Scholar
• YangC, ZhengJ, XueY, et al. The effect of MCM3AP-AS1/miR-211/KLF5/AGGF1 axis regulating glioblastoma angiogenesis. Front Mol Neurosci. 2018;10:437. doi:10.3389/fnmol.2017.0043729375300
   PubMed Web of Science ®Google Scholar
• LiW, FuQ, ManW, et al. LncRNA OR3A4 participates in the angiogenesis of hepatocellular carcinoma through modulating AGGF1/akt/mTOR pathway. Eur J Pharmacol. 2019;849:106–114. doi:10.1016/j.ejphar.2019.01.04930710550
   PubMed Web of Science ®Google Scholar
• ManiSA, YangJ, BrooksM, et al. Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers. Proc Natl Acad Sci U S A. 2007;104(24):10069–10074. doi:10.1073/pnas.070390010417537911
   PubMed Web of Science ®Google Scholar
• ZhouZ, ZhangL, XieB, et al. FOXC2 promotes chemoresistance in nasopharyngeal carcinomas via induction of epithelial mesenchymal transition. Cancer Lett. 2015;363(2):137–145. doi:10.1016/j.canlet.2015.04.00825896630
   PubMed Web of Science ®Google Scholar
• LiC, DingH, TianJ, et al. Forkhead box protein C2 promotes epithelial-mesenchymal transition, migration and invasion in cisplatin-resistant human ovarian cancer cell line (SKOV3/CDDP). Cell Physiol Biochem. 2016;39(3):1098–1110. doi:10.1159/00044781827562816
   PubMedGoogle Scholar
• BowersLW, RossiEL, McDonellSB, et al. Leptin signaling mediates obesity-associated CSC enrichment and EMT in preclinical TNBC models. Mol Cancer Res. 2018;16(5):869–879. doi:10.1158/1541-7786.MCR-17-050829453319
   PubMed Web of Science ®Google Scholar
• BorretzenA, GravdalK, HaukaasSA, et al. FOXC2 expression and epithelial-mesenchymal phenotypes are associated with castration resistance, metastasis and survival in prostate cancer. J Pathol Clin Res. 2019;5(4):272–286. doi:10.1002/cjp2.14231464093
   PubMedGoogle Scholar
• AgnihotriNS, AstekarM. The role of novel prognostic markers PROX1 and FOXC2 in carcinogenesis of oral squamous cell carcinoma. J Exp Ther Oncol. 2018;12(3):171–184.29790306
   PubMed Web of Science ®Google Scholar
• QiY, MoK, ZhangT. A transcription factor that promotes proliferation, migration, invasion, and epithelial-mesenchymal transition of ovarian cancer cells and its possible mechanisms. Biomed Eng Online. 2021;20(1):83. doi:10.1186/s12938-021-00919-y34399777
   PubMed Web of Science ®Google Scholar
• ZhouWM, WuGL, HuangJ, et al. Low expression of PDK1 inhibits renal cell carcinoma cell proliferation, migration, invasion and epithelial mesenchymal transition through inhibition of the PI3K-PDK1-Akt pathway. Cell Signal. 2019;56:1–14. doi:10.1016/j.cellsig.2018.11.01630465826
   PubMed Web of Science ®Google Scholar
• IchikawaR, KawasakiR, IwataA, et al. MicroRNA‑126‑3p suppresses HeLa cell proliferation, migration and invasion, and increases apoptosis via the PI3K/PDK1/AKT pathway. Oncol Rep. 2020;43(4):1300–1308. doi:10.3892/or.2020.751232323808
   PubMed Web of Science ®Google Scholar