Comparisons of Outcomes Between Adolescent and Young Adult with Older Patients After Radical Resection of Pancreatic Ductal Adenocarcinoma by Propensity Score Matching: A Single-Center Study

References

• Miller KD, Fidler-Benaoudia M, Keegan TH, Hipp HS, Jemal A, Siegel RL. Cancer statistics for adolescents and young adults, 2020. CA Cancer J Clin. 2020;70(6):443–459. doi:10.3322/caac.2163732940362
   PubMed Web of Science ®Google Scholar
• Coccia PF, Pappo AS, Beaupin L, et al. Adolescent and young adult oncology, Version 2.2018, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2018;16(1):66–97. doi:10.6004/jnccn.2018.000129295883
   PubMed Web of Science ®Google Scholar
• Close AG, Dreyzin A, Miller KD, Seynnaeve B, Rapkin LB. Adolescent and young adult oncology-past, present, and future. CA Cancer J Clin. 2019;69(6):485–496. doi:10.3322/caac.2158531594027
   PubMed Web of Science ®Google Scholar
• Tricoli JV, Bleyer A. Adolescent and young adult cancer biology. Cancer J. 2018;24(6):267–274. doi:10.1097/PPO.000000000000034330480571
   PubMed Web of Science ®Google Scholar
• Bleyer A, Barr R, Hayes-Lattin B, Thomas D, Ellis C, Anderson B. The distinctive biology of cancer in adolescents and young adults. Nat Rev Cancer. 2008;8(4):288–298. doi:10.1038/nrc234918354417
   PubMed Web of Science ®Google Scholar
• Berkman AM, Livingston JA, Merriman K, et al. Long-term survival among 5-year survivors of adolescent and young adult cancer. Cancer-Am Cancer Soc. 2020;126(16):3708–3718. doi:10.1002/cncr.33003
   Web of Science ®Google Scholar
• Liu L, Moke DJ, Tsai KY, et al. A reappraisal of sex-specific cancer survival trends among adolescents and young adults in the United States. J Natl Cancer Inst. 2019;111(5):509–518. doi:10.1093/jnci/djy14030321398
   PubMedGoogle Scholar
• Kamisawa T, Wood LD, Itoi T, Takaori K. Pancreatic cancer. Lancet. 2016;388(10039):73–85. doi:10.1016/S0140-6736(16)00141-026830752
   PubMed Web of Science ®Google Scholar
• Siegel RL, Miller KD, Jemal A. Cancer statistics. CA Cancer J Clin. 2019;69(1):7–34. doi:10.3322/caac.2155130620402
   PubMed Web of Science ®Google Scholar
• Rahib L, Smith BD, Aizenberg R, Rosenzweig AB, Fleshman JM, Matrisian LM. Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States. Cancer Res. 2014;74(11):2913–2921. doi:10.1158/0008-5472.CAN-14-015524840647
   PubMed Web of Science ®Google Scholar
• Muniraj T, Jamidar PA, Aslanian HR. Pancreatic cancer: a comprehensive review and update. Dis Mon. 2013;59(11):368–402. doi:10.1016/j.disamonth.2013.08.00124183261
   PubMed Web of Science ®Google Scholar
• Ansari D, Althini C, Ohlsson H, Andersson R. Early-onset pancreatic cancer: a population-based study using the SEER registry. Langenbecks Arch Surg. 2019;404(5):565–571. doi:10.1007/s00423-019-01810-031377855
   PubMed Web of Science ®Google Scholar
• Mcwilliams RR, Maisonneuve P, Bamlet WR, et al. Risk factors for early-onset and very-early-onset pancreatic adenocarcinoma: a pancreatic cancer case-control consortium (PanC4) analysis. Pancreas. 2016;45(2):311–316. doi:10.1097/MPA.000000000000039226646264
   PubMed Web of Science ®Google Scholar
• Tavakkoli A, Singal AG, Waljee AK, et al. Racial disparities and trends in pancreatic cancer incidence and mortality in the United States. Clin Gastroenterol Hepatol. 2020;18(1):171–178.e10. doi:10.1016/j.cgh.2019.05.05931202981
   PubMed Web of Science ®Google Scholar
• Amin MB, Edge S, Greene F, et al. AJCC Cancer Staging Manual. 8th ed. New York, NY: Springer-Verlag; 2017.
   Google Scholar
• Barbas AS, Turley RS, Ceppa EP, et al. Comparison of outcomes and the use of multimodality therapy in young and elderly people undergoing surgical resection of pancreatic cancer. J Am Geriatr Soc. 2012;60(2):344–350. doi:10.1111/j.1532-5415.2011.03785.x22211710
   PubMed Web of Science ®Google Scholar
• Bassi C, Marchegiani G, Dervenis C, et al. The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 years after. Surgery. 2017;161(3):584–591. doi:10.1016/j.surg.2016.11.01428040257
   PubMed Web of Science ®Google Scholar
• Wente MN, Veit JA, Bassi C, et al. Postpancreatectomy hemorrhage (PPH): an International Study Group of Pancreatic Surgery (ISGPS) definition. Surgery. 2007;142(1):20–25. doi:10.1016/j.surg.2007.02.00117629996
   PubMed Web of Science ®Google Scholar
• Wente MN, Bassi C, Dervenis C, et al. Delayed gastric emptying (DGE) after pancreatic surgery: a suggested definition by the International Study Group of Pancreatic Surgery (ISGPS). Surgery. 2007;142(5):761–768. doi:10.1016/j.surg.2007.05.00517981197
   PubMed Web of Science ®Google Scholar
• Austin PC. Optimal caliper widths for propensity-score matching when estimating differences in means and differences in proportions in observational studies. Pharm Stat. 2011;10(2):150–161. doi:10.1002/pst.43320925139
   PubMed Web of Science ®Google Scholar
• Tesfaye AA, Kamgar M, Azmi A, Philip PA. The evolution into personalized therapies in pancreatic ductal adenocarcinoma: challenges and opportunities. Expert Rev Anticancer Ther. 2018;18(2):131–148. doi:10.1080/14737140.2018.141784429254387
   PubMed Web of Science ®Google Scholar
• He J, Edil BH, Cameron JL, et al. Young patients undergoing resection of pancreatic cancer fare better than their older counterparts. J Gastrointest Surg. 2013;17(2):339–344. doi:10.1007/s11605-012-2066-423184271
   PubMed Web of Science ®Google Scholar
• Raimondi S, Maisonneuve P, Lowenfels AB. Epidemiology of pancreatic cancer: an overview. Nat Rev Gastroenterol Hepatol. 2009;6(12):699–708. doi:10.1038/nrgastro.2009.17719806144
   PubMed Web of Science ®Google Scholar
• Brune KA, Lau B, Palmisano E, et al. Importance of age of onset in pancreatic cancer kindreds. J Natl Cancer Inst. 2010;102(2):119–126. doi:10.1093/jnci/djp46620068195
   PubMedGoogle Scholar
• Abe T, Blackford AL, Tamura K, et al. Deleterious germline mutations are a risk factor for neoplastic progression among high-risk individuals undergoing pancreatic surveillance. J Clin Oncol. 2019;37(13):1070–1080. doi:10.1200/JCO.18.0151230883245
   PubMed Web of Science ®Google Scholar
• Eguchi H, Yamaue H, Unno M, et al. Clinicopathological characteristics of young patients with pancreatic cancer: an analysis of data from pancreatic cancer registry of Japan Pancreas Society. Pancreas. 2016;45(10):1411–1417. doi:10.1097/MPA.000000000000063627171511
   PubMed Web of Science ®Google Scholar
• Neoptolemos JP, Palmer DH, Ghaneh P, et al. Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, Phase 3 trial. Lancet. 2017;389(10073):1011–1024. doi:10.1016/S0140-6736(16)32409-628129987
   PubMed Web of Science ®Google Scholar
• Conroy T, Hammel P, Hebbar M, et al. FOLFIRINOX or gemcitabine as adjuvant therapy for pancreatic cancer. N Engl J Med. 2018;379(25):2395–2406. doi:10.1056/NEJMoa180977530575490
   PubMed Web of Science ®Google Scholar
• Strobel O, Neoptolemos J, Jager D, Buchler MW. Optimizing the outcomes of pancreatic cancer surgery. Nat Rev Clin Oncol. 2019;16(1):11–26. doi:10.1038/s41571-018-0112-130341417
   PubMed Web of Science ®Google Scholar
• Stauffer JA, Grewal MS, Martin JK, Nguyen JH, Asbun HJ. Pancreas surgery is safe for octogenarians. J Am Geriatr Soc. 2011;59(1):184–186. doi:10.1111/j.1532-5415.2010.03223.x21226703
   PubMed Web of Science ®Google Scholar
• Lee MK, Dinorcia J, Reavey PL, et al. Pancreaticoduodenectomy can be performed safely in patients aged 80 years and older. J Gastrointest Surg. 2010;14(11):1838–1846. doi:10.1007/s11605-010-1345-120824366
   PubMed Web of Science ®Google Scholar
• Oliverius M, Kala Z, Varga M, Gürlich R, Lanska V, Kubesova H. Radical surgery for pancreatic malignancy in the elderly. Pancreatology. 2010;10(4):499–502. doi:10.1159/00028870520720452
   PubMed Web of Science ®Google Scholar
• Cho SJ, Yoon JH, Hwang SS, Lee HS. Do young hepatocellular carcinoma patients with relatively good liver function have poorer outcomes than elderly patients? J Gastroenterol Hepatol. 2007;22(8):1226–1231. doi:10.1111/j.1440-1746.2007.04914.x17498220
   PubMed Web of Science ®Google Scholar
• Emile SH, Elfeki H, Shalaby M, Elbalka S, Metwally IH, Abdelkhalek M. Patients with early-onset rectal cancer aged 40 year or less have similar oncologic outcomes to older patients despite presenting in more advanced stage; A retrospective cohort study. Int J Surg. 2020;83:161–168. doi:10.1016/j.ijsu.2020.09.02932980517
   PubMed Web of Science ®Google Scholar
• Llanos O, Butte JM, Crovari F, Duarte I, Guzmán S. Survival of young patients after gastrectomy for gastric cancer. World J Surg. 2006;30(1):17–20. doi:10.1007/s00268-005-7935-516369709
   PubMed Web of Science ®Google Scholar
• Nakamura R, Saikawa Y, Takahashi T, et al. Retrospective analysis of prognostic outcome of gastric cancer in young patients. Int J Clin Oncol. 2011;16(4):328–334. doi:10.1007/s10147-011-0185-721301918
   PubMed Web of Science ®Google Scholar
• Kang JS, Jang JY, Kwon W, Han Y, Kim SW. Clinicopathologic and survival differences in younger patients with pancreatic ductal adenocarcinoma – a propensity score-matched comparative analysis. Pancreatology. 2017;17(5):827–832. doi:10.1016/j.pan.2017.08.01328870389
   PubMed Web of Science ®Google Scholar
• van der Geest LG, Besselink MG, van Gestel YR, et al. Pancreatic cancer surgery in elderly patients: balancing between short-term harm and long-term benefit. A population-based study in the Netherlands. Acta Oncol. 2016;55(3):278–285. doi:10.3109/0284186X.2015.110538126552841
   PubMed Web of Science ®Google Scholar
• Ordonez JE, Hester CA, Zhu H, et al. Clinicopathologic features and outcomes of early-onset pancreatic adenocarcinoma in the United States. Ann Surg Oncol. 2020;27(6):1997–2006. doi:10.1245/s10434-019-08096-y31894482
   PubMed Web of Science ®Google Scholar
• Ramai D, Lanke G, Lai J, et al. Early- and late-onset pancreatic adenocarcinoma: a population-based comparative study. Pancreatology. 2021;21(1):124–129. doi:10.1016/j.pan.2020.12.00733334692
   PubMed Web of Science ®Google Scholar
• Tingstedt B, Weitkamper C, Andersson R. Early onset pancreatic cancer: a controlled trial. Ann Gastroenterol. 2011;24(3):206–212.24713777
   PubMedGoogle Scholar
• Piciucchi M, Capurso G, Valente R, et al. Early onset pancreatic cancer: risk factors, presentation and outcome. Pancreatology. 2015;15(2):151–155. doi:10.1016/j.pan.2015.01.01325708929
   PubMed Web of Science ®Google Scholar
• Ntala C, Debernardi S, Feakins RM, Crnogorac-Jurcevic T. Demographic, clinical, and pathological features of early onset pancreatic cancer patients. Bmc Gastroenterol. 2018;18(1):139. doi:10.1186/s12876-018-0866-z30208959
   PubMed Web of Science ®Google Scholar