High-Intensity Focused Ultrasound Enhanced Anti-Tumor Activities of Paclitaxel in Breast Cancer in vitro and in vivo

References

• Fan L, Strasser-Weippl K, Li JJ, et al. Breast cancer in China. Lancet Oncol. 2014;15(7):e279–89. doi:10.1016/S1470-2045(13)70567-9
   PubMed Web of Science ®Google Scholar
• Assi S, Torrington E, Cheema E, Hamid AA. Adverse drug reactions associated with chemotherapeutic agents used in breast cancer: analysis of patients’ online forums. J Oncol Pharm Pract. 2021;27(1):108–118. doi:10.1177/1078155220915767
   PubMed Web of Science ®Google Scholar
• Salek R, Dehghani M, Mohajeri SA, Talaei A, Fanipakdel A, Javadinia SA. Amelioration of anxiety, depression, and chemotherapy related toxicity after crocin administration during chemotherapy of breast cancer: a double blind, randomized clinical trial. Phytother Res. 2021;35(9):5143–5153. doi:10.1002/ptr.7180
   PubMed Web of Science ®Google Scholar
• Moezian GSA, Javadinia SA, Sales SS, Fanipakdel A, Elyasi S, Karimi G. Oral silymarin formulation efficacy in management of AC-T protocol induced hepatotoxicity in breast cancer patients: a randomized, triple blind, placebo-controlled clinical trial. J Oncol Pharm Pract. 2021;10781552211006182. doi:10.1177/10781552211006182
   Web of Science ®Google Scholar
• Wang Y, Chen Z. Mutation detection and molecular targeted tumor therapies. STEMedicine. 2020;1(1):e11. doi:10.37175/stemedicine.v1i1.11
   Google Scholar
• Sedighi Pashaki A, Mohammadian K, Afshar S, et al. A randomized, controlled, parallel-group, trial on the effects of melatonin on fatigue associated with breast cancer and its adjuvant treatments. Integr Cancer Ther. 2021;20:1534735420988343. doi:10.1177/1534735420988343
   Web of Science ®Google Scholar
• Le XF, Bast RC Jr. Src family kinases and paclitaxel sensitivity. Cancer Biol Ther. 2011;12(4):260–269. doi:10.4161/cbt.12.4.16430
   PubMed Web of Science ®Google Scholar
• Wall ME, Wani MC, Taylor H. Plant antitumor agents, 27. Isolation, structure, and structure activity relationships of alkaloids from Fagara macrophylla. J Nat Prod. 1987;50(6):1095–1099. doi:10.1021/np50054a014
   PubMed Web of Science ®Google Scholar
• McGrogan BT, Gilmartin B, Carney DN, McCann A. Taxanes, microtubules and chemoresistant breast cancer. Biochim Biophys Acta. 2008;1785(2):96–132. doi:10.1016/j.bbcan.2007.10.004
   PubMed Web of Science ®Google Scholar
• Mortal S. Microtubule dynamics in cytoskeleton, neurodegenerative and psychiatric disease. STEMedicine. 2021;2(6):e81. doi:10.37175/stemedicine.v2i6.81
   Google Scholar
• Perez EA. Paclitaxel in breast cancer. Oncologist. 1998;3(6):373–389. doi:10.1634/theoncologist.3-6-373
   PubMedGoogle Scholar
• Rivera E, Gomez H. Chemotherapy resistance in metastatic breast cancer: the evolving role of ixabepilone. Breast Cancer Res. 2010;12(Suppl 2):S2. doi:10.1186/bcr2573
   PubMed Web of Science ®Google Scholar
• Smoter M, Bodnar L, Duchnowska R, Stec R, Grala B, Szczylik C. The role of Tau protein in resistance to paclitaxel. Cancer Chemother Pharmacol. 2011;68(3):553–557. doi:10.1007/s00280-011-1696-7
   PubMed Web of Science ®Google Scholar
• Ganguly A, Yang H, Cabral F. Class III beta-tubulin counteracts the ability of paclitaxel to inhibit cell migration. Oncotarget. 2011;2(5):368–377. doi:10.18632/oncotarget.250
   PubMedGoogle Scholar
• Maloney E, Hwang JH. Emerging HIFU applications in cancer therapy. Int J Hyperthermia. 2015;31(3):302–309. doi:10.3109/02656736.2014.969789
   PubMed Web of Science ®Google Scholar
• Zhang H, Han K. High intensity focused ultrasound enhances anti-tumor immunity through promoting CD4 Th1 effector T cell response. STEMedicine. 2020;1(4):e65. doi:10.37175/stemedicine.v1i4.65
   Google Scholar
• Feril LB, Fernan RL, Tachibana K. High-intensity focused ultrasound in the treatment of breast cancer. Curr Med Chem. 2021;28(25):5179–5188. doi:10.2174/0929867327666201111143206
   PubMed Web of Science ®Google Scholar
• Tharkar P, Varanasi R, Wong WSF, Jin CT, Chrzanowski W. Nano-enhanced drug delivery and therapeutic ultrasound for cancer treatment and beyond. Front Bioeng Biotechnol. 2019;7:324. doi:10.3389/fbioe.2019.00324
   PubMed Web of Science ®Google Scholar
• Farr N, Wang YN, D’Andrea S, et al. Hyperthermia-enhanced targeted drug delivery using magnetic resonance-guided focussed ultrasound: a pre-clinical study in a genetic model of pancreatic cancer. Int J Hyperthermia. 2018;34(3):284–291. doi:10.1080/02656736.2017.1336675
   PubMed Web of Science ®Google Scholar
• Jain RK. Delivery of molecular and cellular medicine to solid tumors. Adv Drug Deliv Rev. 2001;46(1–3):149–168. doi:10.1016/s0169-409x(00)00131-9
   PubMed Web of Science ®Google Scholar
• Junttila MR, de Sauvage FJ. Influence of tumour micro-environment heterogeneity on therapeutic response. Nature. 2013;501(7467):346–354. doi:10.1038/nature12626
   PubMed Web of Science ®Google Scholar
• Netti PA, Berk DA, Swartz MA, Grodzinsky AJ, Jain RK. Role of extracellular matrix assembly in interstitial transport in solid tumors. Cancer Res. 2000;60(9):2497–2503.
   PubMed Web of Science ®Google Scholar
• Wong C, Stylianopoulos T, Cui J, et al. Multistage nanoparticle delivery system for deep penetration into tumor tissue. Proc Natl Acad Sci U S A. 2011;108(6):2426–2431. doi:10.1073/pnas.1018382108
   PubMed Web of Science ®Google Scholar
• Parodi A, Haddix SG, Taghipour N, et al. Bromelain surface modification increases the diffusion of silica nanoparticles in the tumor extracellular matrix. ACS Nano. 2014;8(10):9874–9883. doi:10.1021/nn502807n
   PubMed Web of Science ®Google Scholar
• Lee S, Han H, Koo H, et al. Extracellular matrix remodeling in vivo for enhancing tumor-targeting efficiency of nanoparticle drug carriers using the pulsed high intensity focused ultrasound. J Control Release. 2017;263:68–78. doi:10.1016/j.jconrel.2017.02.035
   PubMed Web of Science ®Google Scholar
• Oh KS, Han H, Yoon BD, et al. Effect of HIFU treatment on tumor targeting efficacy of docetaxel-loaded Pluronic nanoparticles. Colloids Surf B Biointerfaces. 2014;119:137–144. doi:10.1016/j.colsurfb.2014.05.007
   PubMed Web of Science ®Google Scholar
• Wang S, Shin IS, Hancock H, et al. Pulsed high intensity focused ultrasound increases penetration and therapeutic efficacy of monoclonal antibodies in murine xenograft tumors. J Control Release. 2012;162(1):218–224. doi:10.1016/j.jconrel.2012.06.025
   PubMed Web of Science ®Google Scholar
• You DG, Yoon HY, Jeon S, et al. Deep tissue penetration of nanoparticles using pulsed-high intensity focused ultrasound. Nano Converg. 2017;4(1):30. doi:10.1186/s40580-017-0124-z
   PubMed Web of Science ®Google Scholar
• Choi Y, Han H, Jeon S, et al. Deep tumor penetration of doxorubicin-loaded glycol chitosan nanoparticles using high-intensity focused ultrasound. Pharmaceutics. 2020;12(10):Oct. doi:10.3390/pharmaceutics12100974
   Web of Science ®Google Scholar
• Phenix CP, Togtema M, Pichardo S, Zehbe I, Curiel L. High intensity focused ultrasound technology, its scope and applications in therapy and drug delivery. J Pharm Pharm Sci. 2014;17(1):136–153. doi:10.18433/j3zp5f
   PubMed Web of Science ®Google Scholar
• Cortazar P, Geyer CE Jr. Pathological complete response in neoadjuvant treatment of breast cancer. Ann Surg Oncol. 2015;22(5):1441–1446. doi:10.1245/s10434-015-4404-8
   PubMed Web of Science ®Google Scholar
• Costea T, Vlad OC, Miclea LC, Ganea C, Szollosi J, Mocanu MM. Alleviation of multidrug resistance by flavonoid and non-flavonoid compounds in breast, lung, colorectal and prostate cancer. Int J Mol Sci. 2020;21(2):401. doi:10.3390/ijms21020401
   PubMed Web of Science ®Google Scholar
• Ambudkar SV, Dey S, Hrycyna CA, Ramachandra M, Pastan I, Gottesman MM. Biochemical, cellular, and pharmacological aspects of the multidrug transporter. Annu Rev Pharmacol Toxicol. 1999;39(1):361–398. doi:10.1146/annurev.pharmtox.39.1.361
   PubMed Web of Science ®Google Scholar
• Shen DW, Goldenberg S, Pastan I, Gottesman MM. Decreased accumulation of [14C]carboplatin in human cisplatin-resistant cells results from reduced energy-dependent uptake. J Cell Physiol. 2000;183(1):108–116. doi:10.1002/(SICI)1097-4652(200004)183:1<108::AID-JCP13>3.0.CO;2-4
   PubMed Web of Science ®Google Scholar
• Liu YY, Han TY, Giuliano AE, Cabot MC. Ceramide glycosylation potentiates cellular multidrug resistance. FASEB J. 2001;15(3):719–730. doi:10.1096/fj.00-0223com
   PubMed Web of Science ®Google Scholar
• Fazilat-Panah D, Vakili Ahrari Roudi S, Keramati A, et al. Changes in cytokeratin 18 during neoadjuvant chemotherapy of breast cancer: a prospective study. Iran J Pathol. 2020;15(2):117–126. doi:10.30699/ijp.2020.116238.2261
   PubMedGoogle Scholar
• Buonomo OC, Grasso A, Pistolese CA, et al. Evaluation of concordance between histopathological, radiological and biomolecular variables in breast cancer neoadjuvant treatment. Anticancer Res. 2020;40(1):281–286. doi:10.21873/anticanres.13950
   PubMed Web of Science ®Google Scholar
• Stanislavova N, Karamanliev M, Ivanov T, Yotsov T, Zhou K, Dimitrov D. Is high-intensity focused ultrasound (HIFU) an option for neoadjuvant therapy for borderline resectable pancreatic cancer patients? - a systematic review. Int J Hyperthermia. 2021;38(2):75–80. doi:10.1080/02656736.2021.1909150
   PubMed Web of Science ®Google Scholar
• Chaussy CG, Thuroff S. High-intensity focused ultrasound for the treatment of prostate cancer: a review. J Endourol. 2017;31(S1):S30–S37. doi:10.1089/end.2016.0548
   PubMed Web of Science ®Google Scholar
• Besse HC, Barten-van Rijbroek AD, van der Wurff-jacobs KMG, Bos C, Moonen CTW, Deckers R. Tumor drug distribution after local drug delivery by hyperthermia, in vivo. Cancers. 2019;11(10):Oct. doi:10.3390/cancers11101512
   Web of Science ®Google Scholar
• de Maar JS, Suelmann BBM, Braat M, et al. Phase I feasibility study of magnetic resonance guided high intensity focused ultrasound-induced hyperthermia, lyso-thermosensitive liposomal doxorubicin and cyclophosphamide in de novo stage IV breast cancer patients: study protocol of the i-GO study. BMJ Open. 2020;10(11):e040162. doi:10.1136/bmjopen-2020-040162
   PubMed Web of Science ®Google Scholar
• Zhu L, Chen L. Progress in research on paclitaxel and tumor immunotherapy. Cell Mol Biol Lett. 2019;24(1):40. doi:10.1186/s11658-019-0164-y
   PubMed Web of Science ®Google Scholar
• Jones SE, Erban J, Overmoyer B, et al. Randomized Phase III study of docetaxel compared with paclitaxel in metastatic breast cancer. J Clin Oncol. 2005;23(24):5542–5551. doi:10.1200/JCO.2005.02.027
   PubMed Web of Science ®Google Scholar
• Weaver BA. How Taxol/paclitaxel kills cancer cells. Mol Biol Cell. 2014;25(18):2677–2681. doi:10.1091/mbc.E14-04-0916
   PubMed Web of Science ®Google Scholar
• Sackett D, Fojo T. Taxanes. Cancer Chemother Biol Response Modif. 1997;17:59–79.
   PubMedGoogle Scholar
• De Brabander M, Geuens G, Nuydens R, Willebrords R, De Mey J. Taxol induces the assembly of free microtubules in living cells and blocks the organizing capacity of the centrosomes and kinetochores. Proc Natl Acad Sci USA. 1981;78(9):5608–5612. doi:10.1073/pnas.78.9.5608
   PubMed Web of Science ®Google Scholar
• Abu Samaan TM, Samec M, Liskova A, Kubatka P, Busselberg D. Paclitaxel’s mechanistic and clinical effects on breast cancer. Biomolecules. 2019;9(12):789. doi:10.3390/biom9120789
   PubMed Web of Science ®Google Scholar
• Jordan MA, Toso RJ, Thrower D, Wilson L. Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations. Proc Natl Acad Sci USA. 1993;90(20):9552–9556. doi:10.1073/pnas.90.20.9552
   PubMed Web of Science ®Google Scholar
• Jordan MA, Wilson L. Microtubules and actin filaments: dynamic targets for cancer chemotherapy. Curr Opin Cell Biol. 1998;10(1):123–130. doi:10.1016/s0955-0674(98)80095-1
   PubMed Web of Science ®Google Scholar
• Alexandre J, Batteux F, Nicco C, et al. Accumulation of hydrogen peroxide is an early and crucial step for paclitaxel-induced cancer cell death both in vitro and in vivo. Int J Cancer. 2006;119(1):41–48. doi:10.1002/ijc.21685
   PubMed Web of Science ®Google Scholar
• Islam MT. Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders. Neurol Res. 2017;39(1):73–82. doi:10.1080/01616412.2016.1251711
   PubMed Web of Science ®Google Scholar
• Lenaz G, D’Aurelio M, Merlo Pich M, et al. Mitochondrial bioenergetics in aging. Biochim Biophys Acta. 2000;1459(2–3):397–404. doi:10.1016/s0005-2728(00)00177-8
   PubMed Web of Science ®Google Scholar
• Lv Q, Hu Q, Zhang W, et al. Disturbance of oxidative stress parameters in treatment-resistant bipolar disorder and their association with electroconvulsive therapy response. Int J Neuropsychopharmacol. 2020;23(4):207–216. doi:10.1093/ijnp/pyaa003
   PubMed Web of Science ®Google Scholar