The Age-Adjusted Charlson Comorbidity Index Predicts Prognosis in Elderly Cancer Patients

References

• Zemedikun DT, Gray LJ, Khunti K, Davies MJ, Dhalwani NN. Patterns of multimorbidity in middle-aged and older adults: an analysis of the UK biobank data. Mayo Clin Proc. 2018;93(7):857–866. doi:10.1016/j.mayocp.2018.02.012
   PubMed Web of Science ®Google Scholar
• Zhao L, Leung LH, Wang J, et al. Association between Charlson comorbidity index score and outcome in patients with stage IIIB-IV non-small cell lung cancer. BMC Pulm Med. 2017;17(1):112. doi:10.1186/s12890-017-0452-0
   PubMed Web of Science ®Google Scholar
• Myers RP, Quan H, Hubbard JN, Shaheen AA, Kaplan GG. Predicting in-hospital mortality in patients with cirrhosis: results differ across risk adjustment methods. Hepatology. 2009;49(2):568–577. doi:10.1002/hep.22676
   PubMed Web of Science ®Google Scholar
• Lee DS, Donovan L, Austin PC, et al. Comparison of coding of heart failure and comorbidities in administrative and clinical data for use in outcomes research. Med Care. 2005;43(2):182–188. doi:10.1097/00005650-200502000-00012
   PubMed Web of Science ®Google Scholar
• Hemmelgarn BR, Manns BJ, Quan H, Ghali WA. Adapting the Charlson comorbidity index for use in patients with ESRD. Am J Kidney Dis. 2003;42(1):125–132. doi:10.1016/S0272-6386(03)00415-3
   PubMed Web of Science ®Google Scholar
• Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40(5):373–383. doi:10.1016/0021-9681(87)90171-8
   PubMedGoogle Scholar
• Wu CC, Hsu TW, Chang CM, Yu CH, Lee CC. Age-adjusted Charlson comorbidity index scores as predictor of survival in colorectal cancer patients who underwent surgical resection and chemoradiation. Medicine. 2015;94(2):e431. doi:10.1097/MD.0000000000000431
   PubMed Web of Science ®Google Scholar
• Tian Y, Jian Z, Xu B, Liu H. Age-adjusted Charlson comorbidity index score as predictor of survival of patients with digestive system cancer who have undergone surgical resection. Oncotarget. 2017;8(45):79453–79461. doi:10.18632/oncotarget.18401
   PubMedGoogle Scholar
• Mulcahy CF, Mohamed ASR, Kanwar A, et al. Age-adjusted comorbidity and survival in locally advanced laryngeal cancer. Head Neck. 2018;40(9):2060–2069. doi:10.1002/hed.25200
   PubMed Web of Science ®Google Scholar
• Gimeno-Hernandez J, Iglesias-Moreno MC, Gomez-Serrano M, Carricondo F, Gil-Loyzaga P, Poch-Broto J. The impact of comorbidity on the survival of patients with laryngeal squamous cell carcinoma. Acta Otolaryngol. 2011;131(8):840–846. doi:10.3109/00016489.2011.564651
   PubMed Web of Science ®Google Scholar
• Fuller CD, Mohamed AS, Garden AS, et al. Long-term outcomes after multidisciplinary management of T3 laryngeal squamous cell carcinomas: improved functional outcomes and survival with modern therapeutic approaches. Head Neck. 2016;38(12):1739–1751. doi:10.1002/hed.24532
   PubMed Web of Science ®Google Scholar
• Ouellette JR, Small DG, Termuhlen PM. Evaluation of Charlson-age comorbidity index as predictor of morbidity and mortality in patients with colorectal carcinoma. J Gastrointest Surgery. 2004;8(8):1061–1067. doi:10.1016/j.gassur.2004.09.045
   PubMed Web of Science ®Google Scholar
• Huguet F, Mukherjee S, Javle M. Locally advanced pancreatic cancer: the role of definitive chemoradiotherapy. Clin Oncol. 2014;26(9):560–568. doi:10.1016/j.clon.2014.06.002
   Web of Science ®Google Scholar
• Morgan JL, Richards P, Zaman O, et al. The decision-making process for senior cancer patients: treatment allocation of older women with operable breast cancer in the UK. Cancer Biol Med. 2015;12(4):308–315.
   PubMed Web of Science ®Google Scholar
• Bauschke A, Altendorf-Hofmann A, Mothes H, Rauchfuß F, Settmacher U. Partial liver resection results in a significantly better long-term survival than locally ablative procedures even in elderly patients. J Cancer Res Clin Oncol. 2016;142(5):1099–1108. doi:10.1007/s00432-016-2115-6
   PubMed Web of Science ®Google Scholar
• Nagata T, Adachi Y, Taniguchi A, et al. [Impact of the age-adjusted Charlson comorbidity index on postoperative complications after gastric cancer surgery]. Gan To Kagaku Ryoho. 2021;48(13):1567–1569. Japanese.
   PubMedGoogle Scholar
• Aoyama T, Yamamoto N, Kamiya M, et al. The age-adjusted Charlson comorbidity index is an independent prognostic factor in pancreatic cancer patients who receive curative resection followed by adjuvant chemotherapy. J Cancer Res Ther. 2020;16(Supplement):S116–S121. doi:10.4103/jcrt.JCRT_440_18
   PubMed Web of Science ®Google Scholar
• Chang CM, Yin WY, Wei CK, et al. Adjusted age-adjusted Charlson comorbidity index score as a risk measure of perioperative mortality before cancer surgery. PLoS One. 2016;11(2):e0148076. doi:10.1371/journal.pone.0148076
   PubMed Web of Science ®Google Scholar
• Girotra M, Hansen A, Farooki A, et al. The current understanding of the endocrine effects from immune checkpoint inhibitors and recommendations for management. JNCI Cancer Spectrum. 2018;2(3):pky021. doi:10.1093/jncics/pky021
   PubMed Web of Science ®Google Scholar
• Yamana I, Takeno S, Shimaoka H, et al. Geriatric Nutritional Risk Index as a prognostic factor in patients with esophageal squamous cell carcinoma -retrospective cohort study. Int J Surg. 2018;56:44–48. doi:10.1016/j.ijsu.2018.03.052
   PubMed Web of Science ®Google Scholar
• Koseki Y, Hikage M, Fujiya K, et al. Utility of a modified age-adjusted Charlson Comorbidity Index in predicting cause-specific survival among patients with gastric cancer. Eur J Surg Oncol. 2021;47(8):2010–2015. doi:10.1016/j.ejso.2021.01.026
   PubMed Web of Science ®Google Scholar
• Park JW, Koh DH, Jang WS, et al. Age-adjusted Charlson Comorbidity Index as a prognostic factor for radical prostatectomy outcomes of very high-risk prostate cancer patients. PLoS One. 2018;13(6):e0199365. doi:10.1371/journal.pone.0199365
   PubMed Web of Science ®Google Scholar
• Kim S, Kim DH, Park SY, et al. Association between Charlson comorbidity index and complications of endoscopic resection of gastric neoplasms in elderly patients. BMC Gastroenterol. 2020;20(1):213. doi:10.1186/s12876-020-01360-6
   PubMed Web of Science ®Google Scholar
• Pule L, Buckley E, Niyonsenga T, Banham D, Roder D. Developing a comorbidity index for comparing cancer outcomes in Aboriginal and non-Aboriginal Australians. BMC Health Serv Res. 2018;18(1):776. doi:10.1186/s12913-018-3603-y
   PubMed Web of Science ®Google Scholar
• Jørgensen TL, Hallas J, Friis S, Herrstedt J. Comorbidity in elderly cancer patients in relation to overall and cancer-specific mortality. Br J Cancer. 2012;106(7):1353–1360. doi:10.1038/bjc.2012.46
   PubMed Web of Science ®Google Scholar
• Qu WF, Zhou PY, Liu WR, et al. Age-adjusted Charlson Comorbidity Index predicts survival in intrahepatic cholangiocarcinoma patients after curative resection. Ann Transl Med. 2020;8(7):487. doi:10.21037/atm.2020.03.23
   PubMed Web of Science ®Google Scholar
• Lin JX, Huang YQ, Xie JW, et al. Age-adjusted Charlson Comorbidity Index (ACCI) is a significant factor for predicting survival after radical gastrectomy in patients with gastric cancer. BMC Surg. 2019;19(1):53. doi:10.1186/s12893-019-0513-9
   PubMed Web of Science ®Google Scholar
• Lee JY, Kang HW, Rha KH, et al. Age-adjusted Charlson comorbidity index is a significant prognostic factor for long-term survival of patients with high-risk prostate cancer after radical prostatectomy: a Bayesian model averaging approach. J Cancer Res Clin Oncol. 2016;142(4):849–858. doi:10.1007/s00432-015-2093-0
   PubMed Web of Science ®Google Scholar
• Hurria A. We need a geriatric assessment for oncologists. Nat Clin Pract Oncol. 2006;3(12):642–643. doi:10.1038/ncponc0662
   PubMedGoogle Scholar
• Takahashi M, Takahashi M, Komine K, et al. The G8 screening tool enhances prognostic value to ECOG performance status in elderly cancer patients: a retrospective, single institutional study. PLoS One. 2017;12(6):e0179694. doi:10.1371/journal.pone.0179694
   PubMed Web of Science ®Google Scholar