59
Views
4
CrossRef citations to date
0
Altmetric
Original Research

Deposition of insoluble elastin by pulmonary fibroblasts from patients with COPD is increased by treatment with versican siRNA

, , , &
Pages 267-273 | Published online: 12 Jan 2017

References

  • PauwelsRABuistASCalverleyPMJenkinsCRHurdSSGOLD Scientific CommitteeGlobal strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summaryAm J Respir Crit Care Med200116351256127611316667
  • HoggJCMacklemPTThurlbeckWMSite and nature of airway obstruction in chronic obstructive lung diseaseN Engl J Med196827825135513605650164
  • JefferyPKRemodeling in asthma and chronic obstructive lung diseaseAm J Respir Crit Care Med200116410 pt 2S28S38 Review11734464
  • BlackPNChingPSBeaumontBRanasingheSTaylorGMerrileesMJChanges in elastic fibres in the small airways and alveoli in COPDEur Respir J2008315998100418216063
  • MerrileesMJChingPSBeaumontBHinekAWightTNBlackPNChanges in elastin, elastin binding protein and versican in alveoli in chronic obstructive pulmonary diseaseRespir Res200894118485243
  • HinekAMechamRPKeeleyFRabinovitchMImpaired elastin fiber assembly related to reduced 67-kD elastin-binding protein in fetal lamb ductus arteriosus and in cultured aortic smooth muscle cells treated with chondroitin sulfateJ Clin Invest1991886208320941661296
  • MerrileesMJLemireJMFischerJWRetrovirally mediated overexpression of versican v3 by arterial smooth muscle cells induces tropoelastin synthesis and elastic fiber formation in vitro and in neointima after vascular injuryCirc Res200290448148711884379
  • MerrileesMJBeaumontBWBraunKRNeointima formed by arterial smooth muscle cells expressing versican variant V3 is resistant to lipid and macrophage accumulationArterioscler Thromb Vasc Biol20113161309131621441139
  • LuceyECGoldsteinRHStonePJSniderGLRemodeling of alveolar walls after elastase treatment of hamsters. Results of elastin and collagen mRNA in situ hybridizationAm J Respir Crit Care Med199815825555649700135
  • ZimmermannDRRuoslahtiEMultiple domains of the large fibroblast proteoglycan, versicanEMBO J1989810297529812583089
  • WightTNVersican: a versatile extracellular matrix proteoglycan in cell biologyCurr Opin Cell Biol2002145617623 Review12231358
  • ItoKShinomuraTZakoMUjitaMKimataKMultiple forms of mouse PG-M, a large chondroitin sulfate proteoglycan generated by alternative splicingJ Biol Chem199527029589657822336
  • ZhangJWuLQuJMBaiCXMerrileesMJBlackPNProinflammatory phenotype of COPD fibroblasts not compatible with repair in COPD lungJ Cell Mol Med20121671522153222117690
  • HallgrenONihlbergKDahlbäckMAltered fibroblast proteoglycan production in COPDRespir Res2010115520459817
  • Larsson-CallerfeltAKHallgrenOAndersson-SjölandADefective alterations in the collagen network to prostacyclin in COPD lung fibroblastsRespir Res2013142123406566
  • HinekASmithACCutiongcoEMCallahanJWGrippKWWeksbergRDecreased elastin deposition and high proliferation of fibroblasts from Costello syndrome are related to functional deficiency in the 67-kD elastin-binding proteinAm J Hum Genet200066385987210712202
  • NikkariSTJärveläinenHTWightTNFergusonMClowesAWSmooth muscle cell expression of extracellular matrix genes after arterial injuryAm J Pathol19941446134813568203472
  • VogelCMarcotteEMInsights into the regulation of protein abundance from proteomic and transcriptomic analysesNat Rev Genet2012134227232 Review22411467
  • HuangRMerrileesMJBraunKInhibition of versican synthesis by antisense alters smooth muscle cell phenotype and induces elastic fiber formation in vitro and in neointima after vessel injuryCirc Res200698337037716385080
  • HwangJYJohnsonPYBraunKRRetrovirally mediated overexpression of glycosaminoglycan-deficient biglycan in arterial smooth muscle cells induces tropoelastin synthesis and elastic fiber formation in vitro and in neointimae after vascular injuryAm J Pathol200817361919192818988796
  • PirinenRLeinonenTBöhmJVersican in nonsmall cell lung cancer: relation to hyaluronan, clinicopathologic factors, and prognosisHum Pathol2005361445015712181
  • SoltermannATischlerVArbogastSPrognostic significance of epithelial-mesenchymal and mesenchymal-epithelial transition protein expression in non-small cell lung cancerClin Cancer Res200814227430743719010860