Network pharmacology-based identification of key pharmacological pathways of Yin–Huang–Qing–Fei capsule acting on chronic bronchitis

References

• MiravitllesMMoxifloxacin in the management of exacerbations of chronic bronchitis and COPDInt J Chron Obstruct Pulmon Dis20072319120418229559
   PubMedGoogle Scholar
• KoHJOhSKJinJHSonKHKimHPInhibition of experimental systemic inflammation (septic inflammation) and chronic bronchitis by new phytoformula BL containing Broussonetia papyrifera and Lonicera japonicaBiomol Ther (Seoul)2013211667124009861
   PubMed Web of Science ®Google Scholar
• MathersCDLoncarDProjections of global mortality and burden of disease from 2002 to 2030PLoS Med2006311442442
   PubMed Web of Science ®Google Scholar
• HunterDJReddyKSNoncommunicable diseasesN Engl J Med2013369141336134324088093
   PubMed Web of Science ®Google Scholar
• LiuSShergisJChenXChinese herbal medicine (Weijing decoction) combined with pharmacotherapy for the treatment of acute exacerbations of chronic obstructive pulmonary diseaseEvid Based Complement Alternat Med201420148112
   Google Scholar
• JefferyPKRemodeling in asthma and chronic obstructive lung diseaseAm J Respir Crit Care Med2001164suppl 2S28S3811734464
   PubMed Web of Science ®Google Scholar
• LiuWJiangHZhangREfficacy and safety of Qing-Feng-Gan-Ke granules in patients with postinfectious cough: study protocol of a novel-design phase III placebo-controlled, double-blind randomized trialBMC Complement Altern Med201515111125617057
   PubMed Web of Science ®Google Scholar
• TaoWXuXWangXNetwork pharmacology-based prediction of the active ingredients and potential targets of Chinese herbal radix curcumae formula for application to cardiovascular diseaseJ Ethnopharmacol2013145111023142198
   PubMed Web of Science ®Google Scholar
• LiXMTraditional Chinese herbal remedies for asthma and food allergyJ Allergy Clin Immunol20071201253117560638
   PubMed Web of Science ®Google Scholar
• YeHFXieHBEffect and clinical observation of Yinghuang Qingfei capsules on the hemorrheology of patients with acute exacerbation of chronic obstructive pulmonary diseaseChina Pharm201520151115361538
   Google Scholar
• WangDCaiTWuZJLC-ESI-MS/MS analysis of chemical constituents in Yinhuang Qingfei capsuleChina Meas Test201642033640
   Google Scholar
• LiXLLuFGYiDFExperimental research on the function of anti-influenza virus in vitro of Yinhuang Qingfei capsules containing serumChin Arch Tradit Chin Med201520150511071109
   Google Scholar
• PengZLuFGQuJYExperimental research of Yinhuang Qingfei capsules containing serum on the respiratory syncytial virus in vitroJ Hunan Univ Chin Med201636024043
   Google Scholar
• LiangXLiHLiSA novel network pharmacology approach to analyse traditional herbal formulae: the Liu-Wei-Di-Huang pill as a case studyMol Biosyst20141051014102224492828
   PubMedGoogle Scholar
• WangSTongYNgTBNetwork pharmacological identification of active compounds and potential actions of Erxian decoction in alleviating menopause-related symptomsChin Med201510111225657815
   PubMed Web of Science ®Google Scholar
• ZhangGBLiQYChenQLNetwork pharmacology: a new approach for Chinese herbal medicine researchEvid Based Complement Alternat Med20132013819
   Google Scholar
• LiSZhangBJiangDWeiYZhangNHerb network construction and co-module analysis for uncovering the combination rule of traditional Chinese herbal formulaeBMC Bioinformatics201011suppl 11S1S12
   Google Scholar
• ZhaoFGuochunLYangYShiLXuLYinLA network pharmacology approach to determine active ingredients and rationality of herb combinations of modified-Simiaowan for treatment of goutJ Ethnopharmacol201516811625824593
   PubMed Web of Science ®Google Scholar
• ZhangYQWangSSZhuWLDeciphering the pharmacological mechanism of the Chinese formula Huanglian-Jie-Du decoction in the treatment of ischemic stroke using a systems biology-based strategyActa Pharmacol Sin201536672473325937634
   PubMed Web of Science ®Google Scholar
• ShengSWangJWangLNetwork pharmacology analyses of the antithrombotic pharmacological mechanism of Fufang Xueshuantong capsule with experimental support using disseminated intravascular coagulation ratsJ Ethnopharmacol2014154373574424832112
   PubMed Web of Science ®Google Scholar
• HamoshAScottAFAmbergerJSBocchiniCAMcKusickVAOnline Mendelian inheritance in man (OMIM), a knowledgebase of human genes and genetic disordersNucleic Acids Res200533suppl 1S514S517
   Google Scholar
• XuHTaoYLuPA computational drug-target network for Yuanhu Zhitong prescriptionEvid Based Complement Alternat Med2013201317075
   Google Scholar
• ChenJYMamidipalliSHuanTHAPPI: an online database of comprehensive human annotated and predicted protein interactionsBMC Genomics200910suppl 1S1S11
   Web of Science ®Google Scholar
• D’EustachioPReactome knowledgebase of human biological pathways and processesBioinform Comp Proteomics200937374961
   Google Scholar
• BrownKRJurisicaIOnline predicted human interaction databaseBioinformatics20052192076208215657099
   PubMed Web of Science ®Google Scholar
• KerrienSArandaBBreuzaLThe IntAct molecular interaction database in 2012Nucleic Acids Res20124021841846
   Web of Science ®Google Scholar
• PrasadTKKandasamyKPandeyAHuman protein reference database and human proteinpedia as discovery tools for systems biologyMethods Mol Biol2009577577677919718509
   PubMedGoogle Scholar
• CeolAAryamontriACLicataLMINT, the molecular interaction database: 2009 updateNucleic Acids Res200938532539
   Web of Science ®Google Scholar
• LehneBSchlittTProtein-protein interaction databases: keeping up with growing interactomesHum Genomics20093329129719403463
   PubMedGoogle Scholar
• BeumingTSkrabanekLNivMYPDZBase: a protein–protein interaction database for PDZ-domainsBioinformatics200521682782815513994
   PubMed Web of Science ®Google Scholar
• LiSZhangZQWuLJZhangXGLiYDWangYYUnderstanding ZHENG in traditional Chinese medicine in the context of neuro-endocrine-immune networkIET Syst Biol200711516017370429
   PubMed Web of Science ®Google Scholar
• DennisGJrShermanBTHosackDADAVID: database for annotation, visualization, and integrated discoveryGenome Biol20034533
   PubMed Web of Science ®Google Scholar
• KanehisaMGotoSKEGG: Kyoto encyclopedia of genes and genomesNucleic Acids Res2000281273010592173
   PubMed Web of Science ®Google Scholar
• SteinkeJWBorishLCytokines and chemokinesJ Allergy Clin Immunol20061172441445
   Web of Science ®Google Scholar
• KumarVAbbasAKAsterJCRobbins and Cotran Pathologic Basis of Disease4th edPennsylvaniaElsevier Saunders2005
   Google Scholar
• PlattsMillsTAThe role of immunoglobulin E in allergy and asthmaAm J Respir Crit Care Med20011648 pt 21511435228
   PubMed Web of Science ®Google Scholar
• BjermerLDiamantZCurrent and emerging nonsteroidal anti-inflammatory therapies targeting specific mechanisms in asthma and allergyTreat Respir Med20043323524615350162
   PubMedGoogle Scholar
• NakaeSHoLHYuMMast cell–derived TNF contributes to airway hyperreactivity, inflammation, and TH2 cytokine production in an asthma model in miceJ Allergy Clin Immunol20071201485517482668
   PubMed Web of Science ®Google Scholar
• ZeigerRSSchatzMLiQHigh blood eosinophil count is a risk factor for future asthma exacerbations in adult persistent asthmaJ Allergy Clin Immunol Pract20142674175025439366
   PubMed Web of Science ®Google Scholar
• ShokryDMEltarahonySAOxidant-antioxidant balance in childhood asthmaEgypt J Pediatr Allergy Immunol20131113540
   Google Scholar
• LeeITYangCMRole of NADPH oxidase/ROS in pro-inflammatory mediators-induced airway and pulmonary diseasesBiochem Pharmacol201284558159022587816
   PubMed Web of Science ®Google Scholar
• ReszkaKJSallansLMachaSAirway peroxidases catalyze nitration of the {beta}2-agonist salbutamol and decrease its pharmacological activityJ Pharmacol Exp Ther2011336244044920974700
   PubMed Web of Science ®Google Scholar
• DrögeWFree radicals in the physiological control of cell functionPhysiol Rev2002821479511773609
   PubMed Web of Science ®Google Scholar
• EvansPHalliwellBMicronutrients: oxidant/antioxidant statusBr J Nutr200185suppl 2S67S7411509092
   PubMed Web of Science ®Google Scholar
• ChaudièreJFerrari-IliouRIntracellular antioxidants: from chemical to biochemical mechanismsFood Chem Toxicol1999379–1094996210541450
   PubMed Web of Science ®Google Scholar
• BrozovichFVNicholsonCJDegenCVGaoYZAggarwalMMorganKGMechanisms of vascular smooth muscle contraction and the basis for pharmacologic treatment of smooth muscle disordersPharmacol Rev201668247653227037223
   PubMed Web of Science ®Google Scholar
• NadeemASiddiquiNAlharbiNOAlharbiMMAirway and systemic oxidant-antioxidant dysregulation in asthma: a possible scenario of oxidants spill over from lung into bloodPulm Pharmacol Ther2014291314024929073
   PubMed Web of Science ®Google Scholar
• FranovaSNosal’OvaGACE-inhibitors and defence reflexes of the airwaysActa Physiol Hung199785435936610431607
   PubMedGoogle Scholar
• GunawardhanaLPGibsonPGSimpsonJLBentonMCLeaRABainesKJCharacteristic DNA methylation profiles in peripheral blood monocytes are associated with inflammatory phenotypes of asthmaEpigenetics2014991302131625147914
   PubMed Web of Science ®Google Scholar
• AbebeWMustafaSJA1 adenosine receptor-mediated Ins(1,4,5) P3 generation in allergic rabbit airway smooth muscleAm J Physiol19982755990997
   Google Scholar
• HolgateSTPolosaRTreatment strategies for allergy and asthmaNat Rev Immunol20088321823018274559
   PubMed Web of Science ®Google Scholar
• ValentaRThe future of antigen-specific immunotherapy of allergyNat Rev Immunol20022644645312093011
   PubMed Web of Science ®Google Scholar
• WuKBiYSunKWangCIL-10-producing type 1 regulatory T cells and allergyCell Mol Immunol20074426927517764617
   PubMed Web of Science ®Google Scholar
• GrünigGCorryDBLeachMWSeymourBWKurupVPRennickDMInterleukin-10 is a natural suppressor of cytokine production and inflammation in a murine model of allergic bronchopulmonary aspergillosisJ Exp Med19971856108910999091582
   PubMed Web of Science ®Google Scholar
• NelsonHSDaviesDEWicksJPowellRMPuddicombeSMHolgateSTAirway remodeling in asthma: new insightsJ Allergy Clin Immunol2003111221522512589337
   PubMed Web of Science ®Google Scholar
• WynnTAIL-13 effector functionsAnnu Rev Immunol200321142545612615888
   PubMed Web of Science ®Google Scholar
• GrunigGWarnockMWakilAERequirement for IL-13 independently of IL-4 in experimental asthmaScience19982825397226122639856950
   PubMed Web of Science ®Google Scholar
• GalliSJKalesnikoffJGrimbaldestonMAPiliponskyAMWilliamsCMTsaiMMast cells as “tunable” effector and immunoregulatory cells: recent advancesAnnu Rev Immunol20052374978615771585
   PubMed Web of Science ®Google Scholar
• RenauldJ-CNew insights into the role of cytokines in asthmaJ Clin Pathol200154857758911477111
   PubMed Web of Science ®Google Scholar
• CieslewiczGTomkinsonAAdlerAThe late, but not early, asthmatic response is dependent on IL-5 and correlates with eosinophil infiltrationJ Clin Invest1999104330130810430611
   PubMed Web of Science ®Google Scholar
• DombrowiczDCapronMEosinophils, allergy and parasitesCurr Opin Immunol200113671672011677095
   PubMed Web of Science ®Google Scholar
• WuWSamoszukMKComhairSAEosinophils generate brominating oxidants in allergen-induced asthmaJ Clin Invest2000105101455146310811853
   PubMed Web of Science ®Google Scholar
• VanCEVanDJOpdenakkerGThe MCP/eotaxin subfamily of CC chemokinesCytokine Growth Factor Rev1999101618610379912
   PubMed Web of Science ®Google Scholar
• PonathPDQinSRinglerDJCloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophilsJ Clin Invest19969736046128609214
   PubMed Web of Science ®Google Scholar
• KodaliRBKimWJGalariaIICCL11 (eotaxin) induces CCR3-dependent smooth muscle cell migrationArterioscler Thromb Vasc Biol20042471211121615130922
   PubMed Web of Science ®Google Scholar
• RankinSMConroyDMWilliamsTJEotaxin and eosinophil recruitment: implications for human diseaseMol Med Today200061202710637571
   PubMedGoogle Scholar
• HeathHQinSRaoPChemokine receptor usage by human eosinophils. The importance of CCR3 demonstrated using an antagonistic monoclonal antibodyJ Clin Invest19979921781849005985
   PubMed Web of Science ®Google Scholar
• ZhangGLiQChenQSuSNetwork pharmacology: a new approach for Chinese herbal medicine researchEvid Based Complement Alternat Med20132013862142362142323762149
   PubMedGoogle Scholar
• AiGTianCDengDA combination of 2D similarity search, pharmacophore, and molecular docking techniques for the identification of vascular endothelial growth factor receptor-2 inhibitorsAnticancer Drugs201526439940925569705
   PubMed Web of Science ®Google Scholar