References
- WoodruffPGAgustiARocheNCurrent concepts in targeting COPD pharmacotherapy: making progress towards personalized managementLancet201538599791789179825943943
- WainLVShrineNMillerSUK Brain Expression Consortium (UKBEC)OxGSK ConsortiumNovel insights into the genetics of smoking behavior, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK BiobankLancet Respir Med201531076978126423011
- VogelmeierCHedererBGlaabTPOET-COPD InvestigatorsTiotropium versus Salmeterol for the prevention of exacerbations of COPDN Engl J Med2011364121093110321428765
- ItoKItoMElliottWMDecreased histone deacetylase activity in chronic obstructive pulmonary diseaseN Engl J Med2005352191967197615888697
- LeeSJLeeHRLeeTWUsefulness of neutrophil to lymphocyte ratio in patients with chronic obstructive pulmonary disease: a prospective observational studyKor J Intern Med2016315891898
- GuanyESaric UlasliSAkarONeutrophil-to-lymphocyte ratio in chronic obstructive pulmonary disease: a retrospective studyInflammation201437237438024078279
- SørensenAKHolmgaardDBMygindLHNeutrophil-to-lymphocyte ratio, calprotectin and YKL-40 in patients with chronic obstructive pulmonary disease: correlations and 5-year mortality – a cohort studyJ Inflamm (Lond)2015122025908927
- FurutateRIshiiTMotegiTThe neutrophil to lymphocyte ratio is related to disease severity and exacerbation in patients with chronic obstructive pulmonary diseaseIntern Med201655322322926831014
- LeeHUmS-JKimYSAssociation of the neutrophil-to-lymphocyte ratio with lung function and exacerbations in patients with chronic obstructive pulmonary diseasePLoS One2016116e015651127258044
- KimYJLimBKyungSYParkJWJeongSHComorbidity and inflammatory markers may contribute to predict mortality of high-risk patients with chronic obstructive pulmonary disease exacerbationJ Clin Med Res20168753153627298662
- SahaSBrightlingCEEosinophilic airway inflammation in COPDInt J COPD2006113947
- SaltürkCKarakurtZAdiguzelNDoes eosinophilic COPD exacerbation have a better patient outcome than non-eosinophilic in the intensive care unit?Int J COPD20151018371846
- KaveriSVMouthonLBayryJBasophil and nephritis in lupusN Engl J Med2010363111080108220825323
- TertemizKCOzgen AlpaydinASevincCCould “red cell distribution width” predict COPD severity?Rev Port Pneumol201622419620126809230
- MagnussenHDisseBRodriguez-RoisinRWISDOM InvestigatorsWithdrawal of inhaled glucocorticoids and exacerbations of COPDN Engl J Med2014371141285129425196117
- Global Initiative for Chronic Obstructive Lung Disease (GOLD)Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Pulmonary Disease2016 Available from: http://goldcopd.org/global-strategy-diagnosis-management-prevention-copd-2016Accessed December 1, 2016
- WalterREWilkJBLarsonMGSystemic inflammation and COPD: the Framingham Heart StudyChest20081331192517908709
- DahlMVestboJLangePBojesenSETybjaerg-HansenANordestgaardBGC-reactive protein as a predictor of prognosis in chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2007175325025517053205
- ThomsenMDahlMLangePVestboJNordestgaardBGInflammatory biomarkers and comorbidities in chronic obstructive pulmonary diseaseAm J Respir Crit Care Med20121861098298822983959
- BoschettoPQuintavalleSZeniEAssociation between markers of emphysema and more severe chronic obstructive pulmonary diseaseThorax200661121037104216769715
- BathoornEKerstjensHPostmaDTimensWMacNeeWAirways inflammation and treatment during acute exacerbations of COPDInt J COPD200832217229
- RovinaNKoutsoukouAKoulourisNGInflammation and immune response in COPD: where do we stand?Mediators Inflamm2013201341373523956502
- O’DonnellRBreenDWilsonSInflammatory cells in the airways in COPDThorax200661544845416648353
- BrusselleGGJoosGFBrackeKRNew insights into the immunology of chronic obstructive pulmonary diseaseLancet201137897951015102621907865
- ChungKFAdcockIMMultifaceted mechanisms in COPD: inflammation, immunity, and tissue repair and destructionEur Respir J20083161334135618515558
- DemedtsIKMorel-MonteroALebecqueSElevated MMP-12 protein levels in induced sputum from patients with COPDThorax200661319620116308335
- VestboJHurdSSAgustiAGGlobal strategy for diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summaryAm J Respir Crit Care Med2013187434736522878278
- HoggJCChuFUtokaparchSThe nature of small-airway obstruction in chronic obstructive pulmonary diseaseN Engl J Med2004350262645265315215480
- RetamalesIElliottWMMeshiBAmplification of inflammation in emphysema and its association with latent adenoviral infectionAm J Respir Crit Care Med2001164346947311500352
- Van der StrateBWPostmaDSBrandsmaCACigarette smoke induced emphysema: a role for the B cell?Am J Respir Crit Care Med2006173775175816399994
- GosmanMMWillemseBWJansenDFIncreased number of B-cells in bronchial biopsies in COPDEur Respir J2006271606416387936
- SinghDKolsumUBrightlingCEECLIPSE InvestigatorsEosinophilic inflammation in COPD: prevalence and clinical characteristicsEur Respir J2014441697e170025323230
- WeirMZhaoHHanMKEosinophils in chronic obstructive pulmonary disease, the SPIROMICS cohortAm J Respir Crit Care Med2014189A5902
- BrightlingCEMcKennaSHargadonBSputum eosinophilia and the short term response to inhaled mometasone in chronic obstructive pulmonary diseaseThorax200560319319815741434
- BafadhelMMcKennaSTerrySBlood eosinophils to direct corticosteroid treatment of exacerbations of chronic obstructive pulmonary disease. A randomized placebo-controlled trialAm J Respir Crit Care Med20121861485522447964
- PavordIDLettisSLocantoreNBlood eosinophils and inhaled corticosteroid/long acting β-2 agonist efficacy in COPDThorax201671211812526585525
- WatzHWaschkiBBoehmeCExtrapulmonary effects of chronic obstructive pulmonary disease on physical activityAm J Respir Crit Care Med2008177774375118048807
- ZilzCBlaasSHPfeiferMJörresRABudweiserSMental health, serum biomarkers and survival in severe COPD: a pilot studyMultidiscip Respir Med201611326788321
- CoteCZilberbergMDModySHDordellyLJCelliBHaemoglobin level and its clinical impact in a cohort of patients with COPDEur Respir J200729592392917251227
- SimilowskiTAgustíAMacNeeWSchönhoferBThe potential impact of anaemia of chronic disease in COPDEur Respir J200627239039616452598
- SolerNEsperattiMEwigSSputum purulence-guided antibiotic use in hospitalized patients with exacerbation of COPDEur Respir J20124061344135322523352
- CorsonelloAPedoneCBattagliaSPaglinoGBelliaVIncalziRAC-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) as inflammation markers in elderly patients with stable chronic obstructive pulmonary disease (COPD)Arch Gerontol Geriatr201153219019521074870