55
Views
8
CrossRef citations to date
0
Altmetric
Clinical Trial Report

Bronchodilator efficacy of extrafine glycopyrronium bromide: the Glyco 2 study

, , , , , & show all
Pages 2001-2014 | Published online: 07 Jul 2017

References

  • Global Initiative for Chronic Obstructive Lung DiseaseGlobal strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease Available from: www.goldcopd.orgAccessed December 21, 2016
  • NiewoehnerDERiceKCoteCPrevention of exacerbations of chronic obstructive pulmonary disease with tiotropium, a once-daily inhaled anticholinergic bronchodilator: a randomized trialAnn Intern Med2005143531732616144890
  • DusserDBravoMLIaconoPThe effect of tiotropium on exacerbations and airflow in patients with COPDEur Respir J200627354755516507855
  • HalpinDMenjogeSVielKPatient-level pooled analysis of the effect of tiotropium on COPD exacerbations and related hospitalisationsPrim Care Respir J200918210611319407916
  • CasaburiRMahlerDAJonesPWA long-term evaluation of once-daily inhaled tiotropium in chronic obstructive pulmonary diseaseEur Respir J200219221722411866001
  • TashkinDPCelliBSennSA 4-year trial of tiotropium in chronic obstructive pulmonary diseaseN Engl J Med2008359151543155418836213
  • BrusascoVHodderRMiravitllesMKorduckiLTowseLKestenSHealth outcomes following treatment for six months with once daily tiotropium compared with twice daily salmeterol in patients with COPDThorax200358539940412728159
  • FrithPAThompsonPJRatnavadivelRGlycopyrronium once-daily significantly improves lung function and health status when combined with salmeterol/fluticasone in patients with COPD: the GLISTEN study, a randomized controlled trialThorax201570651952725841237
  • SinghDPapiACorradiMSingle inhaler triple therapy vs inhaled corticosteroid plus long-acting β2-agonist therapy for chronic obstructive pulmonary disease (TRILOGY): a double-blind, parallel group, randomized controlled trialLancet20163881004896397327598678
  • VestboJPapiACorradiMSingle inhaler extrafine triple therapy vs long-acting muscarinic antagonist therapy for chronic obstructive pulmonary disease (TRINITY): a double-blind, parallel group, random-ized controlled trialLancet2017389100821919192928385353
  • KerwinEHébertJGallagherNEfficacy and safety of NVA237 vs placebo and tiotropium in patients with COPD: the GLOW2 studyEur Respir J20124051106111423060624
  • ArievichHOverendTRenardDA novel model-based approach for dose determination of glycopyrronium bromide in COPDBMC Pulm Med20121217423217058
  • RennardSFogartyCReisnerCRandomized study of the safety, pharmacokinetics, and bronchodilatory efficacy of a proprietary glycopyrronium metered-dose inhaler in study patients with chronic obstructive pulmonary diseaseBMC Pulm Med20141411825027304
  • LeakerBRBarnesPJJonesCRTutuncuASinghDEfficacy and safety of nebulized glycopyrrolate for administration using a high efficiency nebulizer in patients with chronic obstructive pulmonary diseaseBr J Clin Pharmacol201579349250025243340
  • SinghDRaviAReidFBuckHO’ConnorGDownGBroncho-dilator effects, pharmacokinetics and safety of PSX1002-GB, a novel glycopyrronium bromide formulation, in COPD patients; a randomized crossover studyPulm Pharmacol Ther20163791426827913
  • RabeKFTimmerWSagkriotisAVielKComparison of a combination of tiotropium plus formoterol to salmeterol plus fluticasone in moderate COPDChest2008134225526218403672
  • MahlerDAD’UrzoABatemanEDINTRUST-1 and INTRUST-2 study investigatorsConcurrent use of indacaterol plus tiotropium in patients with COPD provides superior bronchodilation compared with tiotropium alone: a randomized, double-blind comparisonThorax201267978178822544891
  • BatemanEDFergusonGTBarnesNDual bronchodilation with QVA149 vs single bronchodilator therapy: the SHINE studyEur Respir J20134261484149423722616
  • BuhlRMaltaisFAbrahamsRTiotropium and olodaterol fixed-dose combination vs mono-components in COPD (GOLD 2–4)Eur Respir J201545496997925573406
  • DecramerMAnzuetoAKerwinEEfficacy and safety of umeclidinium plus vilanterol vs tiotropium, vilanterol, or umeclidinium monotherapies over 24 weeks in patients with chronic obstructive pulmonary disease: results from two multicentre, blinded, randomized controlled trialsLancet Respir Med20142647248624835833
  • MahlerDADecramerMD’UrzoADual bronchodilation with QVA149 reduces patient-reported dyspnoea in COPD: the BLAZE studyEur Respir J20144361599160924176997
  • MaltaisFSinghSDonaldACEffects of a combination of umeclidinium/vilanterol on exercise endurance in patients with chronic obstructive pulmonary disease: two randomized, double-blind clinical trialsTher Adv Respir Dis20148616918125452426
  • SilerTMKerwinESousaARDonaldAAliRChurchAEfficacy and safety of umeclidinium added to fluticasone furoate/vilanterol in chronic obstructive pulmonary disease: results of two randomized studiesRespir Med201510991155116326117292
  • SinghDJonesPWBatemanEDEfficacy and safety of aclidinium bromide/formoterol fumarate fixed-dose combinations compared with individual components and placebo in patients with COPD (ACLIFORM-COPD): a multicentre, randomized studyBMC Pulm Med201414117825404569
  • TashkinDPVargheseSTCombined treatment with formoterol and tiotropium is more efficacious than treatment with tiotropium alone in patients with chronic obstructive pulmonary disease, regardless of smoking status, inhaled corticosteroid use, baseline severity, or genderPulm Pharmacol Ther201124114715220659577
  • van NoordJAAumannJLJanssensEEffects of tiotropium with and without formoterol on airflow obstruction and resting hyperinflation in patients with COPDChest2006129350951716537846
  • van NoordJABuhlRLaforceCQVA149 demonstrates superior bronchodilation compared with indacaterol or placebo in patients with chronic obstructive pulmonary diseaseThorax201065121086109120978028
  • ZuWallackRAllenLHernandezGTingNAbrahamsREfficacy and safety of combining olodaterol Respimat(®) and tiotropium Handi-Haler(®) in patients with COPD: results of two randomized, double-blind, active-controlled studiesInt J Chron Obstruct Pulmon Dis201491133114425342898
  • JungKSParkHYParkSYComparison of tiotropium plus fluti-casone propionate/salmeterol with tiotropium in COPD: a randomized controlled studyRespir Med2012106338238921975275
  • SinghDBrooksJHaganGCahnAO’ConnorBJSuperiority of “triple” therapy with salmeterol/fluticasone propionate and tiotropium bromide vs individual components in moderate to severe COPDThorax200863759259818245142
  • ChatterjeeAShahMD’SouzaAOBechtelBCraterGDalalAAObservational study on the impact of initiating tiotropium alone vs tiotropium with fluticasone propionate/salmeterol combination therapy on outcomes and costs in chronic obstructive pulmonary diseaseRespir Res2012131522340019
  • WelteTMiravitllesMHernandezPEfficacy and tolerability of budesonide/formoterol added to tiotropium in patients with chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2009180874175019644045
  • PriceDWestDBrusselleGManagement of COPD in the UK primary-care setting: an analysis of real-life prescribing patternsInt J Chron Obstruct Pulmon Dis2014988990525210450
  • ScichiloneNBenfanteAMorandiLBelliniFPapiAImpact of extrafine formulations of inhaled combinations on patient-related outcomes in asthma and COPDPatient Relat Outcome Meas2014515316225473323
  • SørheimICJohannessenAGulsvikABakkePSSilvermanEKDemeoDLGender differences in COPD: are women more susceptible to smoking effects than men?Thorax201065648048520522842
  • AryalSDiaz-GuzmanEManninoDMInfluence of sex on chronic obstructive pulmonary disease risk and treatment outcomesInt J Chron Obstruct Pulmon Dis201491145115425342899
  • JainNKThakkarMSJainNRohanKASharmaMChronic obstructive pulmonary disease: Does gender really matter?Lung India201128425826222084538
  • VestboJSorianoJBAndersonJACalverleyPPauwelsRJonesPGender does not influence the response to the combination of salme-terol and fluticasone propionate in COPDRespir Med200498111045105015526804
  • TashkinDCelliBKestenSLystigTDecramerMEffect of tiotro-pium in men and women with COPD: Results of the 4-year UPLIFT® trialRespir Med2010104101495150420418083
  • DumitrasSSechaudRDrollmannAEffect of cimetidine, a model drug for inhibition of the organic cation transport (OCT2/MATE1) in the kidney, on the pharmacokinetics of glycopyrroniumInt J Clin Pharmacol Ther2013511077177924040847
  • D’UrzoAFergusonGTvan NoordJAEfficacy and safety of once-daily NVA237 in patients with moderate-to-severe COPD: the GLOW1 trialRespir Res20111215622151296
  • WangCSunTHuangYEfficacy and safety of once-daily glycopyrronium in predominantly Chinese patients with moderate-to-severe chronic obstructive pulmonary disease: the GLOW7 studyInt J Chron Obstruct Pulmon Dis201510576825609940
  • SinghDSchröder-BaboWCohuetGThe bronchodilator effects of extrafine glycopyrronium added to combination treatment with beclometasone dipropionate plus formoterol in COPD: a randomized crossover study (the TRIDENT study)Respir Med2016114849027109816