888
Views
24
CrossRef citations to date
0
Altmetric
Review

Updated Perspectives on Pulmonary Hypertension in COPD

ORCID Icon, , & ORCID Icon
Pages 1315-1324 | Published online: 09 Jun 2020

References

  • SimonneauG, MontaniD, CelermajerDS, et al. Haemodynamic definitions and updated clinical classification of pulmonary hypertension. Eur Respir J. 2019;53(1):1801913. doi:10.1183/13993003.01913-201830545968
  • KovacsG, BergholdA, ScheidlS, OlschewskiH. Pulmonary arterial pressure during rest and exercise in healthy subjects: a systematic review. Eur Respir J. 2009;34(4):888–894. doi:10.1183/09031936.0014560819324955
  • HoffmannJ, WilhelmJ, OlschewskiA, KwapiszewskaG. Microarray analysis in pulmonary hypertension. Eur Respir J. 2016;48(1):229–241. doi:10.1183/13993003.02030-201527076594
  • ChaouatA, BugnetA-S, KadaouiN, et al. Severe pulmonary hypertension and chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2005;172(2):189–194. doi:10.1164/rccm.200401-006OC15831842
  • WeitzenblumE, SautegeauA, EhrhartM, MammosserM, HirthC, RoegelE. Long-term course of pulmonary arterial pressure in chronic obstructive pulmonary disease. Am Rev Respir Dis. 1984;130(6):993–998. doi:10.1164/arrd.1984.130.6.9936439091
  • PortilloK, TorralbaY, BlancoI, et al. Pulmonary hemodynamic profile in chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2015;10:1313–1320. doi:10.2147/COPD.S7818026203238
  • HildeJM, SkjørtenI, HansteenV, et al. Haemodynamic responses to exercise in patients with COPD. Eur Respir J. 2013;41(5):1031–1041. doi:10.1183/09031936.0008561222903957
  • SantosS, PeinadoVI, RamírezJ, et al. Characterization of pulmonary vascular remodelling in smokers and patients with mild COPD. Eur Respir J. 2002;19(4):632–638. doi:10.1183/09031936.02.0024590211998991
  • PeinadoVI, GómezFP, BarberàJA, et al. Pulmonary vascular abnormalities in chronic obstructive pulmonary disease undergoing lung transplant. J Hear Lung Transpl. 2013;32(12):1262–1269. doi:10.1016/j.healun.2013.09.007
  • SantosS, PeinadoVI, RamírezJ, et al. Enhanced expression of vascular endothelial growth factor in pulmonary arteries of smokers and patients with moderate chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2003;167(9):1250–1256. doi:10.1164/rccm.200210-1233OC12615615
  • CarlsenJ, Hasseriis AndersenK, BoesgaardS, IversenM, SteinbrüchelD, Bøgelund AndersenC. Pulmonary arterial lesions in explanted lungs after transplantation correlate with severity of pulmonary hypertension in chronic obstructive pulmonary disease. J Hear Lung Transpl. 2013;32(3):347–354. doi:10.1016/j.healun.2012.11.014
  • BunelV, GuyardA, DauriatG, et al. Pulmonary arterial histologic lesions in patients with COPD with severe pulmonary hypertension. Chest. 2019;156(1):33–44. doi:10.1016/j.chest.2019.02.33330872017
  • BarberàJA, BlancoI. Pulmonary hypertension in patients with chronic obstructive pulmonary disease: advances in pathophysiology and management. Drugs. 2009;69(9):1153–1171. doi:10.2165/00003495-200969090-0000219537834
  • BlancoI, PiccariL, BarberàJA. Pulmonary vasculature in COPD: the silent component. Respirology. 2016;21(6):984–994. doi:10.1111/resp.1277227028849
  • OpitzI, UlrichS. Pulmonary hypertension in chronic obstructive pulmonary disease and emphysema patients: prevalence, therapeutic options and pulmonary circulatory effects of lung volume reduction surgery. J Thorac Dis. 2018;10(Suppl 23):S2763–S2774. doi:10.21037/jtd.2018.07.6330210830
  • WashkoGR, NardelliP, AshSY, et al. Arterial vascular pruning, right ventricular size, and clinical outcomes in chronic obstructive pulmonary disease a longitudinal observational study. Am J Respir Crit Care Med. 2019;200(4):454–461. doi:10.1164/rccm.201811-2063OC30758975
  • RahaghiFN, ArgemíG, NardelliP, et al. Pulmonary vascular density: comparison of findings on computed tomography imaging with histology. Eur Respir J. 2019;54(2):1900370. doi:10.1183/13993003.00370-201931196942
  • ScharfSM, IqbalM, KellerC, CrinerG, LeeS, FesslerHE. Hemodynamic characterization of patients with severe emphysema. Am J Respir Crit Care Med. 2002;166(3):314–322. doi:10.1164/rccm.210702712153963
  • SysolJR, MachadoRF. Classification and pathophysiology of pulmonary hypertension. Contin Cardiol Educ. 2018;4(1):2–12. doi:10.1002/cce2.71
  • WeitzenblumE, ApprillM, OswaldM, ChaouatA, ImbsJL. Pulmonary hemodynamics in patients with chronic obstructive pulmonary disease before and during an episode of peripheral edema. Chest. 1994;105(5):1377–1382. doi:10.1378/chest.105.5.13778181323
  • Oswald-MammosserM, OswaldT, NyankiyeE, DickeleMC, GrangeD, WeitzenblumE. Non-invasive diagnosis of pulmonary hypertension in chronic obstructive pulmonary disease. Comparison of ECG, radiological measurements, echocardiography and myocardial scintigraphy. Eur J Respir Dis. 1987;71(5):419–429.3443164
  • TanabeN, TaniguchiH, TsujinoI, et al. Multi-institutional retrospective cohort study of patients with severe pulmonary hypertension associated with respiratory diseases. Respirology. 2015;20(5):805–812. doi:10.1111/resp.1253025828844
  • LangeTJ, BaronM, SeilerI, ArztM, PfeiferM. Outcome of patients with severe ph due to lung disease with and without targeted therapy. Cardiovasc Ther. 2014;32(5):202–208. doi:10.1111/1755-5922.1208424909193
  • GreinerS, JudA, AurichM, et al. Reliability of noninvasive assessment of systolic pulmonary artery pressure by doppler echocardiography compared to right heart catheterization: analysis in a large patient population. J Am Heart Assoc. 2014;3(4). doi:10.1161/JAHA.114.001103
  • NowakJ, HudzikB, JastrzȩbskiD, et al. Pulmonary hypertension in advanced lung diseases: echocardiography as an important part of patient evaluation for lung transplantation. Clin Respir J. 2018;12(3):930–938. doi:10.1111/crj.1260828052583
  • D’AndreaA, StanziolaA, Di PalmaE, et al. Right ventricular structure and function in idiopathic pulmonary fibrosis with or without pulmonary hypertension. Echocardiography. 2016;33(1):57–65. doi:10.1111/echo.1299226096076
  • WellsJM, WashkoGR, HanMLK, et al. Pulmonary arterial enlargement and acute exacerbations of COPD. N Engl J Med. 2012;367(10):913–921. doi:10.1056/NEJMoa120383022938715
  • YagiM, TaniguchiH, KondohY, et al. CT-determined pulmonary artery to aorta ratio as a predictor of elevated pulmonary artery pressure and survival in idiopathic pulmonary fibrosis. Respirology. 2017;22(7):1393–1399. doi:10.1111/resp.1306628488784
  • AlkukhunL, WangXF, AhmedMK, et al. Non-invasive screening for pulmonary hypertension in idiopathic pulmonary fibrosis. Respir Med. 2016;117:65–72. doi:10.1016/j.rmed.2016.06.00127492515
  • CosteF, BenlalaI, DournesG, GirodetPO, LaurentF, BergerP. Assessing pulmonary hypertension in COPD. Is there a role for computed tomography? Int J COPD. 2019;14:2065–2079. doi:10.2147/COPD.S207363
  • RahaghiFN, Vegas-Sanchez-FerreroG, MinhasJK, et al. Ventricular geometry from non-contrast non-ECG-gated CT scans: an imaging marker of cardiopulmonary disease in smokers. Acad Radiol. 2017;24(5):594–602. doi:10.1016/j.acra.2016.12.00728215632
  • Agoston-ColdeaL, LupuS, MocanT. Pulmonary artery stiffness by cardiac magnetic resonance imaging predicts major adverse cardiovascular events in patients with chronic obstructive pulmonary disease. Sci Rep. 2018;8(1). doi:10.1038/s41598-018-32784-6
  • JohnsCS, RajaramS, CapenerDA, et al. Non-invasive methods for estimating mPAP in COPD using cardiovascular magnetic resonance imaging. Eur Radiol. 2018;28(4):1438–1448. doi:10.1007/s00330-017-5143-y29147768
  • KovacsG, AgustiA, BarberáJA, et al. Pulmonary vascular involvement in chronic obstructive pulmonary disease is there a pulmonary vascular phenotype? Am J Respir Crit Care Med. 2018;198(8):1000–1011. doi:10.1164/rccm.201801-0095PP29746142
  • WeitzenblumE, MammosserM, EhrhartM. Evolution and prognosis of pulmonary hypertension in chronic obstructive pulmonary diseases. Herz. 1986;11(3):147–154.3744269
  • NathanSD, BarberaJA, GaineSP, et al. Pulmonary hypertension in chronic lung disease and hypoxia. Eur Respir J. 2019;53(1):1801914. doi:10.1183/13993003.01914-201830545980
  • BoerrigterBG, BogaardHJ, TripP, et al. Ventilatory and cardiocirculatory exercise profiles in COPD: the role of pulmonary hypertension. Chest. 2012;142(5):1166–1174. doi:10.1378/chest.11-279822556320
  • EhlkenN, LichtblauM, KloseH, et al. Exercise training improves peak oxygen consumption and haemodynamics in patients with severe pulmonary arterial hypertension and inoperable chronic thrombo-embolic pulmonary hypertension: a prospective, randomized, controlled trial. Eur Heart J. 2016;37(1):35–44. doi:10.1093/eurheartj/ehv33726231884
  • MedrekSK, SharafkhanehA, SpiegelmanAM, KakA, PanditLM. Admission for COPD exacerbation is associated with the clinical diagnosis of pulmonary hypertension: results from a retrospective longitudinal study of a veteran population. COPD J Chronic Obstr Pulm Dis. 2017;14(5):484–489. doi:10.1080/15412555.2017.1336209
  • VachiéryJL, TedfordRJ, RosenkranzS, et al. Pulmonary hypertension due to left heart disease. Eur Respir J. 2019;53(1):1801897. doi:10.1183/13993003.01897-201830545974
  • AlbertRK, AuDH, BlackfordAL, et al. A randomized trial of long-term oxygen for COPD with moderate desaturation. N Engl J Med. 2016;375(17):1617–1627. doi:10.1056/NEJMoa160434427783918
  • GredicM, BlancoI, KovacsG, et al. Pulmonary hypertension in chronic obstructive pulmonary disease. Br J Pharmacol. 2020:bph.14979. doi:10.1111/bph.14979.
  • VituloP, StanziolaA, ConfalonieriM, et al. Sildenafil in severe pulmonary hypertension associated with chronic obstructive pulmonary disease: a randomized controlled multicenter clinical trial. J Hear Lung Transpl. 2017;36(2):166–174. doi:10.1016/j.healun.2016.04.010
  • ChenX, TangS, LiuK, et al. Therapy in stable chronic obstructive pulmonary disease patients with pulmonary hypertension: a systematic review and meta-analysis. J Thorac Dis. 2015;7(3):309–319. doi:10.3978/j.issn.2072-1439.2015.02.0825922708
  • PrinsKW, DuvalS, MarkowitzJ, PritzkerM, ThenappanT. Chronic use of PAH-specific therapy in world health organization group III pulmonary hypertension: a systematic review and meta-analysis. Pulm Circ. 2017;7(1):145–155. doi:10.1086/69001728680574
  • ParkJ, SongJH, ParkDA, LeeJS, DoLS, OhYM. Systematic review and meta-analysis of pulmonary hypertension specific therapy for exercise capacity in chronic obstructive pulmonary disease. J Korean Med Sci. 2013;28(8):1200–1206. doi:10.3346/jkms.2013.28.8.120023960448
  • RaoRS, SinghS, SharmaBB, AgarwalVV, SinghV. Sildenafil improves six-minute walk distance in chronic obstructive pulmonary disease: a randomised, double-blind, placebo-controlled trial. Indian J Chest Dis Allied Sci. 2011;53(2):81–85.21545068
  • ValerioG, BraccialeP, Grazia D’agostinoA. Effect of bosentan upon pulmonary hypertension in chronic obstructive pulmonary disease. Ther Adv Respir Dis. 2009;3(1):15–21. doi:10.1177/175346580810349919293199
  • BlancoI, GimenoE, MunozPA, et al. Hemodynamic and gas exchange effects of sildenafil in patients with chronic obstructive pulmonary disease and pulmonary hypertension. Am J Respir Crit Care Med. 2010;181(3):270–278. doi:10.1164/rccm.200907-0988OC19875684
  • LedererDJ, BartelsMN, SchlugerNW, et al. Sildenafil for chronic obstructive pulmonary disease: a randomized crossover trial. COPD J Chronic Obstruct Pulm Dis. 2012;9(3):268–275. doi:10.3109/15412555.2011.651180
  • StolzD, RaschH, LinkaA, et al. A randomised, controlled trial of bosentan in severe COPD. Eur Respir J. 2008;32(3):619–628. doi:10.1183/09031936.0001130818448495
  • BlancoI, SantosS, GeaJ, et al. Sildenafil to improve respiratory rehabilitation outcomes in COPD: a controlled trial. Eur Respir J. 2013;42(4):982–992. doi:10.1183/09031936.0017631223429918
  • CalcaianuG, CanuetM, SchullerA, EnacheI, ChaouatA, KesslerR. Pulmonary arterial hypertension-specific drug therapy in COPD patients with severe pulmonary hypertension and mild-to-moderate airflow limitation. Respiration. 2016;91(1):9–17. doi:10.1159/00044130426492415
  • GrünigE, EichstaedtC, BarberàJ-A, et al. ERS statement on exercise training and rehabilitation in patients with severe chronic pulmonary hypertension. Eur Respir J. 2019;53(2):1800332. doi:10.1183/13993003.00332-201830578391