283
Views
14
CrossRef citations to date
0
Altmetric
Original Research

Identification of Patient Profiles with High Risk of Hospital Re-Admissions for Acute COPD Exacerbations (AECOPD) in France Using a Machine Learning Model

, , , ORCID Icon, ORCID Icon, , , , , & show all
Pages 949-962 | Published online: 30 Apr 2020

References

  • Global Initiative for Chronic Obstructive Lung Disease G. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease. Updated 2013; 2019.
  • LozanoR, NaghaviM, ForemanK, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380(9859):2095–2128. doi:10.1016/S0140-6736(12)61728-023245604
  • MathersCD, LoncarD. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med. 2006;3(11):e442. doi:10.1371/journal.pmed.003044217132052
  • RocheN, DalmayF, PerezT, et al. Impact of chronic airflow obstruction in a working population. Eur Respir J. 2008;31(6):1227–1233. doi:10.1183/09031936.0008960718216058
  • PipernoD, HuchonG, PribilC, BoucotI, SimilowskiT. The burden of COPD in France: results from the confronting COPD survey. Respir Med. 2003;97 Suppl C:S33–42. doi:10.1016/S0954-6111(03)80023-912647941
  • HuchonGJ, VergnenegreA, NeukirchF, BramiG, RocheN, PreuxPM. Chronic bronchitis among French adults: high prevalence and underdiagnosis. Eur Respir J. 2002;20(4):806–812. doi:10.1183/09031936.02.0004200212412668
  • FuhrmanC, DelmasM-C. Épidémiologie descriptive de la bronchopneumopathie chronique obstructive (BPCO) en France. [Descriptive epidemiology of Chronic Obstructive Pulmonary Disease (COPD) in France]. Rev Malad Respir. 2010;27(2):160–168. doi:10.1016/j.rmr.2009.08.003 [In French].
  • LaurendeauC, ChouaidC, RocheN, TerriouxP, GourmelenJ, DetournayB. Prise en charge et coûts de la bronchopneumopathie chronique obstructive en France en 2011. [Management and costs of chronic pulmonary obstructive disease in France in 2011]. Rev Mal Respir. 2015;32(7):682–691. doi:10.1016/j.rmr.2014.10.731 [In French].25613440
  • Soler-CatalunaJJ, Martinez-GarciaMA, Roman SanchezP, SalcedoE, NavarroM, OchandoR. Severe acute exacerbations and mortality in patients with chronic obstructive pulmonary disease. Thorax. 2005;60(11):925–931. doi:10.1136/thx.2005.04052716055622
  • PereraPN, ArmstrongEP, SherrillDL, SkrepnekGH. Acute exacerbations of COPD in the United States: inpatient burden and predictors of costs and mortality. Copd. 2012;9(2):131–141. doi:10.3109/15412555.2011.65023922409371
  • FournierM, TonnelAB, HoussetB, et al. Impact économique de la BPCO en France: étude SCOPE. [Economic impact of COPD in France: SCOPE study]. Rev Mal Respir. 2005;22(2 Pt 1):247–255. doi:10.1016/S0761-8425(05)85478-6 [In French].16092163
  • HurstJR, VestboJ, AnzuetoA, et al. Susceptibility to exacerbation in chronic obstructive pulmonary disease. N Engl J Med. 2010;363(12):1128–1138. doi:10.1056/NEJMoa090988320843247
  • MullerovaH, MaselliDJ, LocantoreN, et al. Hospitalized exacerbations of COPD: risk factors and outcomes in the ECLIPSE cohort. Chest. 2015;147(4):999–1007. doi:10.1378/chest.14-065525356881
  • HanMK, KazerooniEA, LynchDA, et al. Chronic obstructive pulmonary disease exacerbations in the COPDGene study: associated radiologic phenotypes. Radiology. 2011;261(1):274–282. doi:10.1148/radiol.1111017321788524
  • HanMK, QuibreraPM, CarrettaEE, et al. Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort. Lancet Respir Med. 2017;5(8):619–626. doi:10.1016/S2213-2600(17)30207-228668356
  • ManninoDM, Tal-SingerR, LomasDA, et al. Plasma fibrinogen as a biomarker for mortality and hospitalized exacerbations in people with COPD. Chronic Obstr Pulm Dis. 2015;2(1):23–34. doi:10.15326/jcopdf.2.1.2014.013825685850
  • BreimanL, FriedmanJ, StoneCJ, OlshenRA. Classification and Regression Trees. Belmont: Wadsworth International; 1984.
  • RennardSI. The promise of observational studies (ECLIPSE, SPIROMICS, and COPDGene) in achieving the goal of personalized treatment of chronic obstructive pulmonary disease. Semin Respir Crit Care Med. 2015;36(4):478–490. doi:10.1055/s-0000007526238636
  • RennardSI, LocantoreN, DelafontB, et al. Identification of five chronic obstructive pulmonary disease subgroups with different prognoses in the ECLIPSE cohort using cluster analysis. Ann Am Thorac Soc. 2015;12(3):303–312. doi:10.1513/AnnalsATS.201403-125OC25642832
  • KoppadSH, KumarA Application of big data analytics in healthcare system to predict COPD. International Conference on Circuit, Power and Computing Technologies [ICCPCT]; 2016; Nagercoil, India.
  • Ministere des Solidarites et de la Santé. Guide methodologique de production des informations relatives a l’activite medicale et a sa facturation en medecine, chirurgie, obstetrique et odontologie. [Methodological guide for the production of information relating to medical activity and its invoicing in medicine, surgery, obstetrics and dentistry]. Bull Off. 2014. [In French].
  • BezinJ, DuongM, LassalleR, et al. The national healthcare system claims databases in France, SNIIRAM and EGB: powerful tools for pharmacoepidemiology. Pharmacoepidemiol Drug Saf. 2017;26(8):954–962. doi:10.1002/pds.v26.828544284
  • FuhrmanC, DelmasMC. Hospitalisations pour exacerbations de BPCO: Comment les identifier à partir des données du programme de médicalisation des systèmes d’information? [Hospitalizations for COPD exacerbations: How to identify them from the data of the information systems medicalization program?]. Saint-Maurice: Institut de veille sanitaire; 2009. [In French].
  • ReyG, JouglaE, FouilletA, HemonD. Ecological association between a deprivation index and mortality in France over the period 1997–2001: variations with spatial scale, degree of urbanicity, age, gender and cause of death. BMC Public Health. 2009;9:33. doi:10.1186/1471-2458-9-3319161613
  • De OliveiraH, ProdelM, AugustoV Binary classification on French hospital data: benchmark of 7 machine learning algorithms. Paper presented at: IEEE International Conference on Systems, Man, and Cybernetics; 2018; Miyazaki, Japan.
  • DonaldsonGC, LawM, KowlessarB, et al. Impact of prolonged exacerbation recovery in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2015;192(8):943–950. doi:10.1164/rccm.201412-2269OC26151174
  • DonaldsonGC, SeemungalTA, BhowmikA, WedzichaJA. Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax. 2002;57(10):847–852. doi:10.1136/thorax.57.10.84712324669
  • DonaldsonGC, MullerovaH, LocantoreN, et al. Factors associated with change in exacerbation frequency in COPD. Respir Res. 2013;14:79. doi:10.1186/1465-9921-14-7923899210
  • BuhrRG, JacksonNJ, KominskiGF, DubinettSM, OngMK, MangioneCM. Comorbidity and thirty-day hospital readmission odds in chronic obstructive pulmonary disease: a comparison of the Charlson and Elixhauser comorbidity indices. BMC Health Serv Res. 2019;19(1):701. doi:10.1186/s12913-019-4549-431615508
  • MahboubB, AlzaabiA, IqbalMN, et al. Comorbidities associated with COPD in the Middle East and North Africa region: association with severity and exacerbations. Int J Chron Obstruct Pulmon Dis. 2016;11:273–280. doi:10.2147/COPD.S9062626917957
  • CavaillesA, Brinchault-RabinG, DixmierA, et al. Comorbidities of COPD. Eur Respir Rev. 2013;22(130):454–475. doi:10.1183/09059180.0000861224293462
  • GudmundssonG, GislasonT, JansonC, et al. Risk factors for rehospitalisation in COPD: role of health status, anxiety and depression. Eur Respir J. 2005;26(3):414–419. doi:10.1183/09031936.05.0007850416135721
  • RegvatJ, ZmitekA, VegnutiM, KosnikM, SuskovicS. Anxiety and depression during hospital treatment of exacerbation of chronic obstructive pulmonary disease. J Int Med Res. 2011;39(3):1028–1038. doi:10.1177/14732300110390033821819737
  • AbramsTE, Vaughan-SarrazinM, Van der WegMW. Acute exacerbations of chronic obstructive pulmonary disease and the effect of existing psychiatric comorbidity on subsequent mortality. Psychosomatics. 2011;52(5):441–449. doi:10.1016/j.psym.2011.03.00521907063
  • MorganAD, ZakeriR, QuintJK. Defining the relationship between COPD and CVD: what are the implications for clinical practice? Ther Adv Respir Dis. 2018;12:1753465817750524. doi:10.1177/175346581775052429355081
  • MaclayJD, MacNeeW. Assessment of cardiovascular comorbidity In: RabeKF, WedzichaJA, WoutersEFM, editors. COPD and Comorbidity. Vol. Monograph 59 European Respiratory Society; 2013:28–49.
  • PatelARC, DonaldsonGC, MackayAJ, WedzichaJA, HurstJR. The impact of ischemic heart disease on symptoms, health status, and exacerbations in patients with COPD. Chest. 2012;141(4):851–857. doi:10.1378/chest.11-085321940771
  • BlanchetteCM, BerrySR, LaneSJ. Advances in chronic obstructive pulmonary disease among older adults. Curr Opin Pulm Med. 2011;17(2):84–89. doi:10.1097/MCP.0b013e32834316ff21178625
  • BenzE, TrajanoskaK, LahousseL, et al. Sarcopenia in COPD: a systematic review and meta-analysis. Eur Respir Rev. 2019;28:154. doi:10.1183/16000617.0049-2019
  • DhamaneAD, MoretzC, ZhouY, et al. COPD exacerbation frequency and its association with health care resource utilization and costs. Int J Chron Obstruct Pulmon Dis. 2015;10:2609–2618. doi:10.2147/COPD26664109
  • Assurance Maladie. Améliorer la qualité du système de santé et maîtriser les dépenses. Propositions de l’Assurance Maladie pour 2019. [Improve the quality of the health system and control spending. Health Insurance proposals for 2019]. Paris: Caisse Nationale de l’Assurance Maladie; 2018. [In French].
  • MolinariN, ChanezP, RocheN, AhmedE, VachierI, BourdinA. Rising total costs and mortality rates associated with admissions due to COPD exacerbations. Respir Res. 2016;17(1):149. doi:10.1186/s12931-016-0469-627842545
  • ToyEL, BeaulieuNU, McHaleJM, et al. Treatment of COPD: relationships between daily dosing frequency, adherence, resource use, and costs. Respir Med. 2011;105(3):435–441. doi:10.1016/j.rmed.2010.09.00620880687
  • PuhanMA, ScharplatzM, TroostersT, SteurerJ. Respiratory rehabilitation after acute exacerbation of COPD may reduce risk for readmission and mortality – a systematic review. Respir Res. 2005;6:54. doi:10.1186/1465-9921-6-5415943867
  • van BovenJF, ChavannesNH, van der MolenT, Rutten-van MolkenMP, PostmaMJ, VegterS. Clinical and economic impact of non-adherence in COPD: a systematic review. Respir Med. 2014;108(1):103–113. doi:10.1016/j.rmed.2013.08.04424070566
  • HalpinDM, MiravitllesM, MetzdorfN, CelliB. Impact and prevention of severe exacerbations of COPD: a review of the evidence. Int J Chron Obstruct Pulmon Dis. 2017;12:2891–2908. doi:10.2147/COPD.S13947029062228
  • DoatS, SamsonS, Fagot-CampagnaA, TuppinP, MenegauxF. Estimation of breast, prostate, and colorectal cancer incidence using a French administrative database (general sample of health insurance beneficiaries). Rev Epidemiol Sante Publique. 2016;64(3):145–152. doi:10.1016/j.respe.2015.12.02027238161
  • WedzichaJAE-C-C, MiravitllesM, HurstJR, et al. Management of COPD exacerbations: a European Respiratory Society/American Thoracic Society guideline. Eur Respir J. 2017;49(3):1600791. doi:10.1183/13993003.00791-201628298398
  • JouneauS, ChabotF, RocheN. New guidelines for acute COPD exacerbations. Rev Mal Respir. 2017;34(4):279–281. doi:10.1016/j.rmr.2017.05.00128599784
  • Haute Autorité de Santé. Bronchopneumopathie chronique obstructive. Guide du parcours de soins [Chronic obstructive pulmonary disease. Care pathway guidelines]. 2014. [In French].