77
Views
0
CrossRef citations to date
0
Altmetric
Research Letter

Club Cell Secretory Protein (CCSP) is Reduced in Hospitalized Chronic Obstructive Pulmonary Disease (COPD) Exacerbations

ORCID Icon, ORCID Icon, , &
Pages 2461-2464 | Published online: 09 Oct 2020

References

  • BoersJE, AmbergenAW, ThunnissenFB. Number and proliferation of clara cells in normal human airway epithelium. Am J Respir Crit Care Med. 1999;159:1585–1591. doi:10.1164/ajrccm.159.5.980604410228131
  • GuerraS, HalonenM, VasquezMM, et al. Relation between circulating CC16 concentrations, lung function, and development of chronic obstructive pulmonary disease across the lifespan: a prospective study. Lancet Respir Med. 2015;3:613–620. doi:10.1016/S2213-2600(15)00196-426159408
  • HermansC, DongP, RobinM, et al. Determinants of serum levels of surfactant proteins A and B and clara cell protein CC16. Biomarkers. 2003;8(6):461–471. doi:10.1080/1354750031000164702115195678
  • BernardA, MarchandiseFX, DepelchinS, LauwerysR, SibilleY. Clara cell protein in serum and bronchoalveolar lavage. Eur Respir J. 1992;5:1231–1238.1486970
  • LomasDA, SilvermanEK, EdwardsLD, MillerBE, CoxsonHO, Tal-SingerR. Investigators EoCLtIPSEE. Evaluation of serum CC-16 as a biomarker for COPD in the ECLIPSE cohort. Thorax. 2008;63(12):1058–1063. doi:10.1136/thx.2008.10257418757456
  • Laucho-ContrerasME, PolverinoF, TesfaigziY, PilonA, CelliBR, OwenCA. Club Cell Protein 16 (CC16) augmentation: a potential disease-modifying approach for Chronic Obstructive Pulmonary Disease (COPD). Expert Opin Ther Targets. 2016;20(7):869–883. doi:10.1517/14728222.2016.113908426781659
  • LevineCR, GewolbIH, AllenK, et al. The safety, pharmacokinetics, and anti-inflammatory effects of intratracheal recombinant human Clara cell protein in premature infants with respiratory distress syndrome. Pediatr Res. 2005;58(1):15–21. doi:10.1203/01.PDR.0000156371.89952.3515774846