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International Journal of Chronic Obstructive Pulmonary Disease Volume 16, 2021 - Issue
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Original Research

T-Helper 17 Cell/Regulatory T-Cell Imbalance in COPD Combined with T2DM Patients

Cheng Wang1 Second Department of Respiratory Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, 650032, People’s Republic of China
,
Hong Wang2 Department of Burns Surgery, The Second Affiliated Hospital of Kunming Medical University, Kunming, 650101, People’s Republic of China
,
Luming Dai1 Second Department of Respiratory Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, 650032, People’s Republic of China
,
Jianqing Zhang1 Second Department of Respiratory Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, 650032, People’s Republic of China
,
Lizhou Fang1 Second Department of Respiratory Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, 650032, People’s Republic of China
,
Ling Liu1 Second Department of Respiratory Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, 650032, People’s Republic of China
,
Weiping Fu1 Second Department of Respiratory Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, 650032, People’s Republic of China
&
Dang Tang3 First Department of Neurosurgery, The First Affiliated Hospital of Kunming Medical University, Kunming, 650032, People’s Republic of ChinaCorrespondence[email protected]
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Pages 1425-1435 | Published online: 27 May 2021

References

  • Muneswarao J, Verma AK, Hassali Ahmad MA. Global initiative for chronic obstructive lung disease (GOLD) 2018 report: highlighting an incorrect information. Pulm Pharmacol Ther. 2017;49:10. doi:10.1016/j.pupt.2017.12.009
  • Caughey GE, Roughead EE, Vitry AI, et al. Comorbidity in the elderly with diabetes: identification of areas of potential treatment conflicts. Diabetes Res Clin Pract. 2010;87(3):385–393. doi:10.1016/j.diabres.2009.10.019
  • Cazzola M, Bettoncelli G, Sessa E, et al. Prevalence of comorbidities in patients with chronic obstructive pulmonary disease. Respiration. 2010;80(2):112–119. doi:10.1159/000281880
  • Miller J, Edwards LD, Agusti A, et al. Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort. Respir Med. 2013;107(9):1376–1384. doi:10.1016/j.rmed.2013.05.001
  • Crisafulli E 1, Torres A, Huerta A, et al. C-reactive protein at discharge, diabetes mellitus and ≥ 1 hospitalization during previous year predict early readmission in patients with acute exacerbation of chronic obstructive pulmonary disease. COPD. 2015;12(3):306–314. doi:10.3109/15412555.2014.933954
  • Cazzola M, Calzetta L, Rogliani P, et al. High glucose enhances responsiveness of human airways smooth muscle via the Rho/ROCK pathway. Am J Respir Cell Mol Biol. 2012;47(4):509–516. doi:10.1165/rcmb.2011-0449OC
  • Brennan AL, Gyi KM, Wood DM, et al. Airway glucose concentrations and effect on growth of respiratory pathogens in cystic fibrosis. J Cyst Fibros. 2007;6(2):101–109. doi:10.1016/j.jcf.2006.03.009
  • Gläser S, Krüger S, Merkel M, et al. Chronic obstructive pulmonary disease and diabetes mellitus: a systematic review of the literature. Respiration. 2015;89(3):253–264. doi:10.1159/000369863
  • Zhang JC, Chen G, Chen L, et al. TGF-β/BAMBI pathway dysfunction contributes to peripheral Th17/Treg imbalance in chronic obstructive pulmonary disease. Sci Rep. 2016;6:31911. doi:10.1038/srep31911
  • Imani S, Salimian J, Fu J, et al. Th17/Treg-related cytokine imbalance in sulfur mustard exposed and stable chronic obstructive pulmonary (COPD) patients: correlation with disease activity. Immunopharmacol Immunotoxicol. 2016:1–11. doi:10.3109/08923973.2015.1127509
  • Vargas-Rojas MI, Ramírez-Venegas A, Limón-Camacho L, Ochoa L, Hernández-Zenteno R, Sansores RH. Increase of Th17 cells in peripheral blood of patients with chronic obstructive pulmonary disease. Respir Med. 2011;105(11):1648–1654. doi:10.1016/j.rmed.2011.05.017
  • Stefano AD, Caramori G, Gnemmi I, et al. T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients. Clin Exp Immunol. 2010;157(2):316–324. doi:10.1111/j.1365-2249.2009.03965.x
  • Yang X, Huo B, Zhong X, et al. Imbalance between subpopulations of regulatory T cells in patients with acute exacerbation of COPD. COPD. 2017;14(6):618–625. doi:10.1080/15412555.2017.1385055
  • Dawei L, Jinni C, Xiaolin C, et al. Expression of Th17/Treg cells and related cytokines in peripheral blood of diabetes mellitus patients. Prog Mod Biomed. 2016;16(30):5987.
  • Korn T, Bettelli E, Gao W, et al. IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature. 2007;448(7152):484–487. doi:10.1038/nature05970
  • Sun N, Wei X, Wang J, et al. Caveolin-1 promotes the imbalance of Th17/Treg in patients with chronic obstructive pulmonary disease. Inflammation. 2016;39(6):2008–2015. doi:10.1007/s10753-016-0436-x
  • Zeng C, Shi X, Zhang B, et al. The imbalance of Th17/Th1/Tregs in patients with type 2 diabetes: relationship with metabolic factors and complications. J Mol Med. 2012;90(2):175–186. doi:10.1007/s00109-011-0816-5
  • Noack M, Miossec P. Th17 and regulatory T cell balance in autoimmune and inflammatory diseases. Autoimmun Rev. 2014;13(6):668–677. doi:10.1016/j.autrev.2013.12.004
  • Kumar P, Subramaniyam G. Molecular underpinnings of Th17 immune-regulation and their implications in autoimmune diabetes. Cytokine. 2015;71(2):366–376. doi:10.1016/j.cyto.2014.10.010
  • Lei L, Zhong X-N, He Z-Y, et al. IL-21 induction of CD4+ T cell differentiation into Th17 cells contributes to bleomycin-induced fibrosis in mice. Cell Biol Int. 2015;39(4):388–399. doi:10.1002/cbin.10410
  • Jia X, Minghui H, Wang C, et al. Coordinated gene expression of Th17- and Treg-associated molecules correlated with resolution of the monophasic experimental autoimmune uveitis. Mol Vis. 2011;17:1493–1507.
  • Yang HY. Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1. Cell. 2011;146(5):772–784. doi:10.1016/j.cell.2011.07.033
  • Bilate AM, Lafaille J. Induced CD4+Foxp3+ regulatory T cells in immune tolerance. Annu Rev Immunol. 2012;30(30):733–758. doi:10.1146/annurev-immunol-020711-075043

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