References
- Global Initiative for Chronic Obstructive Lung DiseaseGlobal Strategy for the Diagnosis, Management and Prevention of COPDNHLBI/WHO workshop reportBethesda, MDNational Heart, Lung and Blood Institute42001 NIH Publication. No 27011100 Last updated 2014. Available from: http://www.goldcopd.org/guidelines-global-strategy-for-diagnosis-management.htmlAccessed January 27, 2014
- QaseemAWiltTJWeinbergerSEAmerican College of PhysiciansAmerican College of Chest PhysiciansAmerican Thoracic SocietyEuropean Respiratory SocietyDiagnosis and management of stable chronic obstructive pulmonary disease: a clinical practice guideline update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory SocietyAnn Intern Med201115517919121810710
- AppletonSPoolePSmithBVealeALassersonTJChanMMLong-acting beta-agonists for poorly reversible chronic obstructive pulmonary diseaseCochrane Database Syst Rev20063CD00110416855959
- ChongJKarnerCPoolePTiotropium versus long-acting beta-agonists for stable chronic obstructive pulmonary diseaseCochrane Database Syst Rev20129CD00915722972134
- YangIAClarkeMSSimEHFongKMInhaled corticosteroids for stable chronic obstructive pulmonary diseaseCochrane Database Syst Rev20127CD00299122786484
- SpencerSKarnerCCatesCJEvansDJInhaled corticosteroids versus long-acting beta-agonists for chronic obstructive pulmonary diseaseCochrane Database Syst Rev201112CD007033
- YawnBPLiYTianHZhangJArconaSKahlerKHInhaled corticosteroid use in patients with chronic obstructive pulmonary disease and the risk of pneumonia: a retrospective claims data analysisInt J Chron Obstruct Pulmon Dis2013829530423836970
- NanniniLJPoolePMilanSJHolmesRNormansellRCombined corticosteroid and long-acting beta2-agonist in one inhaler versus placebo for chronic obstructive pulmonary diseaseCochrane Database Syst Rev201311CD00379424214176
- CalverleyPMAndersonJACelliBTORCH investigatorsSalmeterol and fluticasone propionate and survival in chronic obstructive pulmonary diseaseN Engl J Med200735677578917314337
- KliberALyndLDSinDDThe effects of long-acting bronchodilators on total mortality in patients with stable chronic obstructive pulmonary diseaseRespir Res2010115620459831
- DongYHLinHHShauWYWuYCChangCHLaiMSComparative safety of inhaled medications in patients with chronic obstructive pulmonary disease: systematic review and mixed treatment comparison meta-analysis of randomised controlled trialsThorax201368485623042705
- CyrMCBeauchesneMFLemièreCAaronSDBlaisLEffects of inhaled corticosteroids in monotherapy or combined with long-acting β2-agonists on mortality among patients with chronic obstructive pulmonary diseaseAnn Pharmacother20104461362220233915
- CazzolaMPageCPCalzettaLMateraMGPharmacology and therapeutics of bronchodilatorsPharmacol Rev20126445050422611179
- CazzolaMRoglianiPSegretiAMateraMGAn update on bronchodilators in Phase I and II clinical trialsExpert Opin Investig Drugs20122114891501
- CazzolaMPageCPRoglianiPMateraMGβ2-agonist therapy in lung diseaseAm J Respir Crit Care Med201318769069623348973
- RossiAPoleseGIndacaterol: a comprehensive reviewInt J Chron Obstruct Pulmon Dis2013835336323922496
- SpinaDCurrent and novel bronchodilators in respiratory diseaseCurr Opin Pulm Med201420738624247039
- AdcockIMCaramoriGKirkhamPAStrategies for improving the efficacy and therapeutic ratio of glucocorticoidsCurr Opin Pharmacol20121224625122445282
- GoldenbergMMPharmaceutical approval updatePharmacy and Therapeutics20133838940324049424
- http://www.ema.europa.eu [homepage on the Internet]Accessed January 27, 2014
- CaramoriGAdcockIMPharmacology of airway inflammation in asthma and COPDPulm Pharmacol Ther20031624727712877818
- CaramoriGCasolariPAdcockIRole of transcription factors in the pathogenesis of asthma and COPDCell Commun Adhes201320214023472830
- RamamoorthySCidlowskiJAExploring the molecular mechanisms of glucocorticoid receptor action from sensitivity to resistanceEndocr Dev201324415623392094
- OakleyRHCidlowskiJAThe biology of the glucocorticoid receptor: new signaling mechanisms in health and diseaseJ Allergy Clin Immunol20131321033104424084075
- SalterMBiggadikeKMatthewsJLPharmacological properties of the enhanced-affinity glucocorticoid fluticasone furoate in vitro and in an in vivo model of respiratory inflammatory diseaseAm J Physiol Lung Cell Mol Physiol2007293L660L66717575011
- BiggadikeKBledsoeRKHassellAMX-ray crystal structure of the novel enhanced-affinity glucocorticoid agonist fluticasone furoate in the glucocorticoid receptor-ligand binding domainJ Med Chem2008513349335218522385
- ValotisAHöggerPHuman receptor kinetics and lung tissue retention of the enhanced-affinity glucocorticoid fluticasone furoateRespir Res200785417650349
- RossiosCToYToMLong-acting fluticasone furoate has a superior pharmacological profile to fluticasone propionate in human respiratory cellsEur J Pharmacol201167024425121920359
- AllenABalJCheesbroughAHamiltonMKempsfordRPharmacokinetics (PK) and pharmacodynamics (PD) of intravenous and inhaled fluticasone furoate (FF) in healthy Caucasian and East Asian subjectsBr J Clin Pharmacol Epub10242013
- AllenABareillePJRousellVMFluticasone furoate, a novel inhaled corticosteroid, demonstrates prolonged lung absorption kinetics in man compared with inhaled fluticasone propionateClin Pharmacokinet201352374223184737
- JohnsonMRennardSAlternative mechanisms for long-acting β2-adrenergic agonists in COPDChest200112025827011451847
- BarnesPJDistribution of receptor targets in the lungProc Am Thorac Soc2004134535116113456
- ChungKFCaramoriGAdcockIMInhaled corticosteroids as combination therapy with beta-adrenergic agonists in airways disease: present and futureEur J Clin Pharmacol20096585387119557399
- HaqueRHakimAMoodleyTInhaled long-acting β2 agonists enhance glucocorticoid receptor nuclear translocation and efficacy in sputum macrophages in COPDJ Allergy Clin Immunol20131321166117324070494
- RothMJohnsonPRRüdigerJJInteraction between glucocorticoids and beta2 agonists on bronchial airway smooth muscle cells through synchronised cellular signallingLancet20023601293129912414205
- ProcopiouPABarrettVJBevanNJSynthesis and structure-activity relationships of long-acting β2 adrenergic receptor agonists incorporating metabolic inactivation: an antedrug approachJ Med Chem2010534522453020462258
- SlackRJBarrettVJMorrisonVSIn vitro pharmacological characterization of vilanterol, a novel long-acting β2-adrenoceptor agonist with 24-hour duration of actionJ Pharmacol Exp Ther201334421823023131596
- HananiaNASharafkhanehABarberRDickeyBFBeta-agonist intrinsic efficacy: measurement and clinical significanceAm J Respir Crit Care Med20021651353135812016095
- HananiaNAFeldmanGZachgoWThe efficacy and safety of the novel long-acting β2 agonist vilanterol in patients with COPD: a randomized placebo-controlled trialChest201214211912722241764
- KempsfordRNorrisVSiedererSVilanterol trifenatate, a novel inhaled long-acting beta2 adrenoceptor agonist, is well tolerated in healthy subjects and demonstrates prolonged bronchodilation in subjects with asthma and COPDPulm Pharmacol Ther20132625626423232038
- SterlingRLimJFrithLSnowiseNGJacquesLHaumannBEfficacy and optimal dosing interval of the long-acting beta2 agonist, vilanterol, in persistent asthma: a randomised trialRespir Med20121061110111522520084
- KumarRKumarDParakhAFluticasone furoate: a new intranasal corticosteroidJ Postgrad Med201258798322387656
- KempsfordRAllenABalJRubinDTombsLThe effect of ketoconazole on the pharmacokinetics and pharmacodynamics of inhaled fluticasone furoate and vilanterol trifenatate in healthy subjectsBr J Clin Pharmacol2013751478148723116485
- AllenAThe relationship between fluticasone furoate systemic exposure and cortisol suppressionClin Pharmacokinet20135288589623719680
- AllenADavisAHardesKTombsLKempsfordRInfluence of renal and hepatic impairment on the pharmacokinetic and pharmacodynamic properties and tolerability of fluticasone furoate and vilanterol in combinationClin Ther2012342316233223200625
- BosciaJAPudiKKZvarichMTSanfordLSiedererSKCrimCEffect of once-daily fluticasone furoate/vilanterol on 24-hour pulmonary function in patients with chronic obstructive pulmonary disease: a randomized, three-way, incomplete block, crossover studyClin Ther2012341655166622789766
- LötvallJBakkePSBjermerLEfficacy and safety of 4 weeks’ treatment with combined fluticasone furoate/vilanterol in a single inhaler given once daily in COPD: a placebo-controlled randomised trialBMJ Open20122e000370
- AgustíAde TeresaLDe BackerWA comparison of the efficacy and safety of once-daily fluticasone furoate/vilanterol with twice-daily fluticasone propionate/salmeterol in moderate to very severe COPDEur Respir J Epub10102013
- BollmeierSGProsserTRCombination of fluticasone furoate and vilanterol for the treatment of chronic obstructive pulmonary diseaseAnn Pharmacother Epub11192013
- KerwinEMScott-WilsonCSanfordLA randomised trial of fluticasone furoate/vilanterol (50/25 μg; 100/25 μg) on lung function in COPDRespir Med201310756056923352226
- MartinezFJBosciaJFeldmanGFluticasone furoate/vilanterol (100/25; 200/25 μg) improves lung function in COPD: a randomised trialRespir Med201310755055923332861
- DransfieldMTBourbeauJJonesPWOnce-daily inhaled fluticasone furoate and vilanterol versus vilanterol only for prevention of exacerbations of COPD: two replicate double-blind, parallel-group, randomised controlled trialsLancet Respir Med2013121022324429127
- VestboJAndersonJBrookRDThe Study to Understand Mortality and Morbidity in COPD (SUMMIT) study protocolEur Respir J2013411017102223018908
- SvedsaterHDalePGarrillKWalkerRWoepseMWQualitative assessment of attributes and ease of use of the ELLIPTATM dry powder inhaler for delivery of maintenance therapy for asthma and COPDBMC Pulm Med2013137224314123
- KelleherDLMehtaRSJean-FrancoisBMSafety, tolerability, pharmacodynamics and pharmacokinetics of umeclidinium and vilanterol alone and in combination: a randomized crossover trialPLoS One20127e5071623284643
- KempsfordRAllenAKellyKSagguPCrimCA repeat-dose thorough QT study of inhaled fluticasone furoate (FF)/vilanterol (VI) combination in healthy subjectsBr J Clin Pharmacol Epub1042013
- NakaharaNWakamatsuAKempsfordRThe safety, pharmacokinetics and pharmacodynamics of a combination of fluticasone furoate and vilanterol in healthy Japanese subjectsInt J Clin Pharmacol Ther20135166067123735179
- HussarDAAhmadAVilanterol trifenatate/fluticasone furoate, lomitapide mesylate, and mipomersen sodiumJ Am Pharm Assoc201353662670
- FromerLBarnesTGarveyCOrtizGSaverDFYawnBInnovations to achieve excellence in COPD diagnosis and treatment in primary carePostgrad Med201012215016420861599
- VestboJAndersonJACalverleyPMAdherence to inhaled therapy, mortality and hospital admission in COPDThorax20096493994319703830
- Simoni-WastilaLWeiYJQianJAssociation of chronic obstructive pulmonary disease maintenance medication adherence with all-cause hospitalization and spending in a Medicare populationAm J Geriatr Pharmacother20121020121022521808
- ÁghTInotaiAMészárosÁFactors associated with medication adherence in patients with chronic obstructive pulmonary diseaseRespiration20118232833421454953
- BourbeauJBartlettSJPatient adherence in COPDThorax20086383183818728206