References
- Niimi T, Keck-Waggoner CL, Popescu NC, et al. UGRP1, a uteroglobin/Clara cell secretory protein-related protein, is a novel lung-enriched downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor. Mol Endocrinol. 2001;15(11):2021–2036. doi:10.1210/mend.15.11.0728
- Kimura S, Hara Y, Pineau T, et al. The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary. Genes Dev. 1996;10:60–69.
- Yokoyama S, Cai Y, Murata M, et al. A novel pathway of LPS uptake through syndecan-1 leading to pyroptotic cell death. Elife. 2018;1:7.
- Chiba Y, Kurotani R, Kusakabe T, et al. Uteroglobin-related protein 1 expression suppresses allergic airway inflammation in mice. Am J Respir Crit Care Med. 2006;173:958–964.
- Kurotani R, Okumura S, Matsubara T, et al. Secretoglobin 3A2 suppresses bleomycin-induced pulmonary fibrosis by transforming growth factor beta signaling down-regulation. J Biol Chem. 2011;286:19682–19692.
- Cai Y, Winn ME, Zehmer JK, et al. Preclinical evaluation of human secretoglobin 3A2 in mouse models of lung development and fibrosis. Am J Physiol Lung Cell Mol Physiol. 2014;306:L10–22.
- Cai Y, Yoneda M, Tomita T, et al. Transgenically-expressed secretoglobin 3A2 accelerates resolution of bleomycin-induced pulmonary fibrosis in mice. BMC Pulm Med. 2015;15:72.
- Kurotani R, Tomita T, Yang Q, et al. Role of secretoglobin 3A2 in lung development. Am J Respir Crit Care Med. 2008;178:389–398.
- Yokoyama S, Nakayama S, Xu L, et al. Secretoglobin 3A2 eliminates human cancer cells through pyroptosis. Cell Death Discov. 2021;7:12.
- Miele L. Antiflammins. Bioactive peptides derived from uteroglobin. Ann N Y Acad Sci. 2000;923:128–140.
- Johansson S, Andersson K, Wennergren G, et al. CC16 inhibits the migration of eosinophils towards the formyl peptide fMLF but not towards PGD2. Inflammation. 2009;32:65–69.
- Knabe L, Petit A, Vernisse C, et al. CCSP counterbalances airway epithelial-driven neutrophilic chemotaxis. Eur Respir J. 2019;1:54.
- Xu M, Yang W, Wang X, et al. Lung Secretoglobin Scgb1a1 Influences Alveolar Macrophage-Mediated Inflammation and Immunity. Front Immunol. 2020;11:584310.
- Elliott JE, Mantilla CB, Pabelick CM, et al. Aging-related changes in respiratory system mechanics and morphometry in mice. Am J Physiol Lung Cell Mol Physiol. 2016;311:L167–176.
- Fukuda K. Aging of the Respiratory Systems. Dokkyo j med sci. 2008;35:219–226.
- Lang MR, Fiaux GW, Gillooly M, et al. Collagen content of alveolar wall tissue in emphysematous and non-emphysematous lungs. Thorax. 1994;49:319–326.
- Branchfield K, Li R, Lungova V, et al. A three-dimensional study of alveologenesis in mouse lung. Dev Biol. 2016;409:429–441.
- Starcher BC. Elastin and the lung. Thorax. 1986;41:577–585.
- Kuge K, Fujii N, Miura Y, et al. Kinetic study of racemization of aspartyl residues in synthetic elastin peptides. Amino Acids. 2004;27:193–197.
- Le Page A, Khalil A, Vermette P, et al. The role of elastin-derived peptides in human physiology and diseases. Matrix Biol. 2019;84:81–96.
- Kido T, Yoneda M, Cai Y, et al. Secretoglobin superfamily protein SCGB3A2 deficiency potentiates ovalbumin-induced allergic pulmonary inflammation. Mediators Inflamm. 2014;2014:216465.
- Dunnill MS. Quantitative methods in the study of pulmonary pathology. Thorax. 1962;17:320–328.
- Robbesom AA, Versteeg EM, Veerkamp JH, et al. Morphological quantification of emphysema in small human lung specimens: comparison of methods and relation with clinical data. Mod Pathol. 2003;16:1–7.
- Saetta M, Shiner RJ, Angus GE, et al. Destructive index: a measurement of lung parenchymal destruction in smokers. Am Rev Respir Dis. 1985;131:764–769.
- Milner JD, Ward JM, Keane-Myers A, et al. Lymphopenic mice reconstituted with limited repertoire T cells develop severe, multiorgan, Th2-associated inflammatory disease. Proc Natl Acad Sci U S A. 2007;104:576–581.
- Melton DW, McManus LM, Gelfond JA, et al. Temporal phenotypic features distinguish polarized macrophages in vitro. Autoimmunity. 2015;48:161–176.
- Anders S, Pyl PT, Huber W. HTSeq–a Python framework to work with high-throughput sequencing data. Bioinformatics. 2015;31:166–169.
- Love MI, Huber W, Anders S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol. 2014;15:550.
- Ten Have-Opbroek AA. The development of the lung in mammals: an analysis of concepts and findings. Am J Anat. 1981;162:201–219.
- Ward JM. Lymphomas and leukemias in mice. Exp Toxicol Pathol. 2006;57:377–381.
- Beatty K, Bieth J, Travis J. Kinetics of association of serine proteinases with native and oxidized alpha-1-proteinase inhibitor and alpha-1-antichymotrypsin. J Biol Chem. 1980;255:3931–3934.
- Janoff A. Elastases and emphysema. Current assessment of the protease-antiprotease hypothesis. Am Rev Respir Dis. 1985;132:417–433.
- Amy RW, Bowes D, Burri PH, et al. Postnatal growth of the mouse lung. J Anat. 1977;124:131–151.
- Naizhen X, Kido T, Yokoyama S, et al. Spatiotemporal Expression of Three Secretoglobin Proteins, SCGB1A1, SCGB3A1, and SCGB3A2, in Mouse Airway Epithelia. J Histochem Cytochem. 2019;67:453–463.
- Schulte H, Muhlfeld C, Brandenberger C. Age-Related Structural and Functional Changes in the Mouse Lung. Front Physiol. 2019;10:1466.
- Loukov D, Naidoo A, Puchta A, et al. Tumor necrosis factor drives increased splenic monopoiesis in old mice. J Leukoc Biol. 2016;100:121–129.
- de la Higuera L, Lopez-Garcia M, Castro M, et al. Fate of a Naive T Cell: a Stochastic Journey. Front Immunol. 2019;10:194.
- Collins RA, Ikegami M, Korfhagen TR, et al. In vivo measurements of changes in respiratory mechanics with age in mice deficient in surfactant protein D. Pediatr Res. 2003;53:463–467.
- Tokieda K, Whitsett JA, Clark JC, et al. Pulmonary dysfunction in neonatal SP-B-deficient mice. Am J Physiol. 1997;273:L875–882.
- Wert SE, Whitsett JA, Nogee LM. Genetic disorders of surfactant dysfunction. Pediatr Dev Pathol. 2009;12:253–274.
- Korutla L, Strayer DS. SP-A as a cytokine: surfactant protein-A-regulated transcription of surfactant proteins and other genes. J Cell Physiol. 1999;178:379–386.
- Sarker M, Jackman D, Booth V. Lung surfactant protein A (SP-A) interactions with model lung surfactant lipids and an SP-B fragment. Biochemistry. 2011;50:4867–4876.
- Botas C, Poulain F, Akiyama J, et al. Altered surfactant homeostasis and alveolar type II cell morphology in mice lacking surfactant protein D. Proc Natl Acad Sci U S A. 1998;95:11869–11874.
- Glasser SW, Burhans MS, Korfhagen TR, et al. Altered stability of pulmonary surfactant in SP-C-deficient mice. Proc Natl Acad Sci U S A. 2001;98:6366–6371.
- Jin H, Ciechanowicz AK, Kaplan AR, et al. Surfactant protein C dampens inflammation by decreasing JAK/STAT activation during lung repair. Am J Physiol Lung Cell Mol Physiol. 2018;314:L882–L892.
- Mulugeta S, Beers MF. Surfactant protein C: its unique properties and emerging immunomodulatory role in the lung. Microbes Infect. 2006;8:2317–2323.