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ORIGINAL RESEARCH

Single-Inhaler Triple Therapy in Patients with Advanced COPD: Bayesian Modeling of the Healthcare Resource Utilization Data and Associated Costs from the IMPACT Trial

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Pages 1633-1642 | Received 02 Oct 2021, Accepted 25 Jun 2022, Published online: 25 Jul 2022

References

  • Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease; 2020. Available from: https://goldcopd.org/wp-content/uploads/2019/11/GOLD-2020-REPORT-ver1.1wms.pdf. Accessed November 26, 2019.
  • Iheanacho I, Zhang S, King D, Rizzo M, Ismaila AS. Economic burden of chronic obstructive pulmonary disease (COPD): a systematic literature review. Int J Chron Obstruct Pulmon Dis. 2020;15:439–460. doi:10.2147/COPD.S234942
  • Bogart MR, Hopson SD, Shih HC, Stanford RH, Coutinho AD. COPD exacerbation costs in the IMPACT study: a within-trial analysis. Am J Manag Care. 2020;26(5):e150–e154.
  • Pascoe SJ, Lipson DA, Locantore N, et al. A phase III randomised controlled trial of single-dose triple therapy in COPD: the IMPACT protocol. Eur Respir J. 2016;48(2):320–330. doi:10.1183/13993003.02165-2015
  • Lipson DA, Barnhart F, Brealey N, et al. Once-daily single-inhaler triple versus dual therapy in patients with COPD. N Engl J Med. 2018;378(18):1671–1680. doi:10.1056/NEJMoa1713901
  • Ismaila AS, Risebrough N, Schroeder M, et al. Cost-effectiveness of once-daily single-inhaler triple therapy in COPD: the IMPACT trial. Int J Chron Obstruct Pulmon Dis. 2019;14:2681–2695. doi:10.2147/COPD.S216072
  • Ismaila AS, Paly V, Schroeder M, et al. IMPACT study single inhaler triple therapy (FF/UMEC/VI) versus FF/VI and UMEC/VI in patients with COPD: healthcare resource utilization and costs – UK. Eur Respir J. 2018;52(Suppl 62):OA2128.
  • MIMS; 2018. Available from: https://www.mims.co.uk/. Accessed November 27, 2019.
  • Personal Social Services Research Unit. Unit costs of health and social care; 2017. Available from: https://www.pssru.ac.uk/project-pages/unit-costs/. Accessed November 27, 2019.
  • National Health Service. National health service reference costs 2016/17; 2016. Available from: https://improvement.nhs.uk/resources/reference-costs/. Accessed November 27, 2019.
  • Rubin DB. Inference and missing data. Biometrika. 1976;63:581–592. doi:10.1093/biomet/63.3.581
  • Rubin DB. Multiple Imputation for Nonresponse in Surveys. New York: Wiley; 1987.
  • Gabrio A, Mason AJ, Baio G. A full Bayesian model to handle structural ones and missingness in economic evaluations from individual‐level data. Stat Med. 2019;8(38):1399–1420. doi:10.1002/sim.8045
  • Gabrio A, Mason AJ, Baio G. Handling missing data in within-trial cost-effectiveness analysis: a review with future recommendations. Pharmacoecon Open. 2017;1(2):79–97. doi:10.1007/s41669-017-0015-6
  • Leurent B, Gomes M, Carpenter JR. Missing data in trial‐based cost‐effectiveness analysis: an incomplete journey. Health Econ. 2018;27(6):1024–1040. doi:10.1002/hec.3654
  • Ismaila AS, Birk R, Shah D, et al. Once-daily triple therapy in patients with advanced COPD: healthcare resource utilization data and associated costs from the FULFIL trial. Adv Ther. 2017;34(9):2163–2172. doi:10.1007/s12325-017-0604-x