999
Views
8
CrossRef citations to date
0
Altmetric
Original Research

Frequency and Severity of Exacerbations of COPD Associated with Future Risk of Exacerbations and Mortality: A UK Routine Health Care Data Study

, , , ORCID Icon, , , & ORCID Icon show all
Pages 427-437 | Published online: 03 Mar 2022

References

  • Hurst JR, Vestbo J, Anzueto A, et al. Susceptibility to exacerbation in chronic obstructive pulmonary disease. N Engl J Med. 2010;363(12):1128–1138. doi:10.1056/NEJMoa0909883
  • Rothnie KJ, Müllerová H, Smeeth L, et al. Natural history of chronic obstructive pulmonary disease exacerbations in a general practice–based population with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2018;198(4):464–471. doi:10.1164/rccm.201710-2029OC
  • Miravitlles M, Ferrer M, Pont A, et al. Effect of exacerbations on quality of life in patients with chronic obstructive pulmonary disease: a 2 year follow up study. Thorax. 2004;59(5):387–395. doi:10.1136/thx.2003.008730
  • Donaldson GC, Seemungal TA, Bhowmik A, Wedzicha J. Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax. 2002;57(10):847–852. doi:10.1136/thorax.57.10.847
  • Seemungal TA, Donaldson GC, Paul EA, et al. Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1998;157(5):1418–1422.
  • Quint JK, Mullerova H, DiSantostefano RL, et al. Validation of chronic obstructive pulmonary disease recording in the Clinical Practice Research Datalink (CPRD-GOLD). BMJ Open. 2014;4(7):e005540. doi:10.1136/bmjopen-2014-005540
  • Wolf A, Dedman D, Campbell J, et al. Data resource profile: clinical Practice Research Datalink (CPRD) Aurum. Int J Epidemiol. 2019;48(6):1740–1740g. doi:10.1093/ije/dyz034
  • Rothnie KJ, Müllerová H, Hurst JR, et al. Validation of the recording of acute exacerbations of COPD in UK Primary Care Electronic Healthcare Records. PLoS One. 2016;11(3):e0151357. doi:10.1371/journal.pone.0151357
  • Rothnie KJ, Müllerová H, Thomas SL, et al. Recording of hospitalizations for acute exacerbations of COPD in UK electronic health care records. Clin Epidemiol. 2016;8:771–782. doi:10.2147/CLEP.S117867
  • Sadatsafavi M, Xie H, Etminan M, et al. The association between previous and future severe exacerbations of chronic obstructive pulmonary disease: updating the literature using robust statistical methodology. PLoS One. 2018;13(1):e0191243–e0191243. doi:10.1371/journal.pone.0191243
  • Hartley BF, Barnes NC, Lettis S, et al. Risk factors for exacerbations and pneumonia in patients with chronic obstructive pulmonary disease: a pooled analysis. Respir Res. 2020;21(1):5. doi:10.1186/s12931-019-1262-0
  • Müllerová H, Shukla A, Hawkins A, et al. Risk factors for acute exacerbations of COPD in a primary care population: a retrospective observational cohort study. BMJ Open. 2014;4(12):e006171. doi:10.1136/bmjopen-2014-006171
  • Margüello MS, Garrastazu R, Ruiz-Nuñez M, et al. Independent effect of prior exacerbation frequency and disease severity on the risk of future exacerbations of COPD: a retrospective cohort study. NPJ Prim Care RespirMed. 2016;26(1):16046. doi:10.1038/npjpcrm.2016.46
  • Gayle AV, Axson EL, Bloom CI, et al. Changing causes of death for patients with chronic respiratory disease in England, 2005-2015. Thorax. 2019;74(5):483. doi:10.1136/thoraxjnl-2018-212514
  • Schmidt SAJ, Johansen MB, Olsen M, et al. The impact of exacerbation frequency on mortality following acute exacerbations of COPD: a registry-based cohort study. BMJ Open. 2014;4(12):e006720. doi:10.1136/bmjopen-2014-006720
  • Falzon C, Soljak M, Elkin SL, Blake ID. Finding the missing millions - the impact of a locally enhanced service for COPD on current and projected rates of diagnosis: a population-based prevalence study using interrupted time series analysis. Primary Care Respir J. 2013;22(1):59–63.
  • Roberts J, Gaduzo S. Finding the ‘missing millions’: do we need incentives to optimise COPD outcomes? Prim Care Respir J. 2013;22(1):12–13. doi:10.4104/pcrj.2013.00024
  • Haroon S, Adab P, Griffin C, et al. Case finding for chronic obstructive pulmonary disease in primary care: a pilot randomised controlled trial. Br J General Pract. 2013;63(606):e55. doi:10.3399/bjgp13X660788
  • Practitioners, R.C.o.G. Fit for the Future: A Vision for General Practice; 2019.