307
Views
0
CrossRef citations to date
0
Altmetric
Original Research

Association Between Serum Sodium and Long-Term Mortality in Critically Ill Patients with Comorbid Chronic Obstructive Pulmonary Disease: Analysis from the MIMIC-IV Database

, ORCID Icon, , , , & show all
Pages 1143-1155 | Published online: 12 May 2022

References

  • Celli BR, Wedzicha JA. Update on clinical aspects of chronic obstructive pulmonary disease. N Engl J Med. 2019;381 (13):1257–1266. doi:10.1056/NEJMra1900500
  • Vogelmeier CF, Criner GJ, Martinez FJ, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease 2017 report. Gold executive summary. Am J Respir Crit Care Med. 2017;195 (5):557–582. doi:10.1164/rccm.201701-0218PP
  • Soriano JB, Abajobir AA, Abate KH, GBD 2015 Chronic Respiratory Disease Collaborators. Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990–2015: a systematic analysis for the Global Burden Of Disease Study 2015. Lancet Respir Med. 2017;5 (9):691–706.
  • Salvi S, Kumar GA, Dhaliwal RS, India State-Level Disease Burden Initiative CRD Collaborators. The burden of chronic respiratory diseases and their heterogeneity across the states of India: the Global Burden of Disease Study 1990–2016. Lancet Glob Health. 2018;6 (12):e1363–e1374.
  • The Lancet Public Health. Ageing: a 21st century public health challenge? Lancet Public Health. 2017;2 (7):e297.
  • Funk GC, Bauer P, Burghuber OC, et al. Prevalence and prognosis of COPD in critically ill patients between 1998 and 2008. Eur Respir J. 2013;41 (4):792–799. doi:10.1183/09031936.00226411
  • Overgaard-Steensen C, Ring T. Clinical review: practical approach to hyponatraemia and hypernatraemia in critically ill patients. Crit Care. 2013;17 (1):206. doi:10.1186/cc11805
  • Funk GC, Lindner G, Druml W, et al. Incidence and prognosis of dysnatremias present on ICU admission. Intensive Care Med. 2010;36 (2):304–311. doi:10.1007/s00134-009-1692-0
  • Tokgöz Akyil F, Akyil M, Çoban Ağca M, et al. Hyponatremia prolongs hospital stay and hypernatremia better predicts mortality than hyponatremia in hospitalized patients with community-acquired pneumonia. Tuberk Toraks. 2019;67 (4):239–247. doi:10.5578/tt.68779
  • Ruiz-Sánchez JG, Núñez-Gil IJ, Cuesta M, et al. Prognostic impact of hyponatremia and hypernatremia in COVID-19 pneumonia. A HOPE-COVID-19 (health outcome predictive evaluation for COVID-19) registry analysis. Front Endocrinol. 2020;11:599255. doi:10.3389/fendo.2020.599255
  • Combs S, Berl T. Dysnatremias in patients with kidney disease. Am J Kidney Dis. 2014;63 (2):294–303. doi:10.1053/j.ajkd.2013.09.017
  • Spatenkova V, Bradac O, de Lacy P, et al. Dysnatremia as a poor prognostic indicator in patients with acute subarachnoid hemorrhage. J Neurosurg Sci. 2017;61 (4):371–379. doi:10.23736/S0390-5616.16.03411-1
  • Garcia-Elias A, Lorenzo IM, Vicente R, et al. IP3 receptor binds to and sensitizes TRPV4 channel to osmotic stimuli via a calmodulin-binding site. J Biol Chem. 2008;283 (46):31284–31288. doi:10.1074/jbc.C800184200
  • Mizuno A, Matsumoto N, Imai M, et al. Impaired osmotic sensation in mice lacking TRPV4. Am J Physiol Cell Physiol. 2003;285 (1):C96–C101. doi:10.1152/ajpcell.00559.2002
  • Yin J, Kuebler WM. Mechanotransduction by TRP channels: general concepts and specific role in the vasculature. Cell Biochem Biophys. 2010;56 (1):1–18. doi:10.1007/s12013-009-9067-2
  • Rugg C, Ströhle M, Treml B, et al. ICU-acquired hypernatremia is associated with persistent inflammation, immunosuppression and catabolism syndrome. J Clin Med. 2020;9 (9):3017. doi:10.3390/jcm9093017
  • Pogson ZE, McKeever TM, Fogarty A. The association between serum osmolality and lung function among adults. Eur Respir J. 2008;32 (1):98–104. doi:10.1183/09031936.00144207
  • Tokgöz Akyıl F, Tural Önür S, Abalı H, et al. Hyponatremia is an independent predictor of emergency department revisits in acute exacerbation of COPD. Clin Respir J. 2021;15 (10):1063–1072. doi:10.1111/crj.13409
  • Goldberger AL, Amaral LA, Glass L, et al. PhysioBank, physiotoolkit, and physioNet: components of a new research resource for complex physiologic signals. Circulation. 2000;101 (23):E215–E220. doi:10.1161/01.cir.101.23.e215
  • Li L, Zou G, Liu J. Preoperative glucose-to-lymphocyte ratio is an independent predictor for acute kidney injury after cardiac surgery in patients in intensive care unit. Int J Gen Med. 2021;14:6529–6537. doi:10.2147/IJGM.S335896
  • Demircan NC, Alan Ö, Başoğlu Tüylü T, et al. Impact of the Charlson comorbidity index on dose-limiting toxicity and survival in locally advanced and metastatic renal cell carcinoma patients treated with first-line sunitinib or pazopanib. J Oncol Pharm Pract. 2020;26 (5):1147–1155. doi:10.1177/1078155219890032
  • Moreno R, Vincent JL, Matos R, et al. The use of maximum SOFA score to quantify organ dysfunction/failure in intensive care. Results of a prospective, multicentre study. working group on sepsis related problems of the ESICM. Intensive Care Med. 1999;25 (7):686–696. doi:10.1007/s001340050931
  • Johnson AE, Kramer AA, Clifford GD. A new severity of illness scale using a subset of acute physiology and chronic health evaluation data elements shows comparable predictive accuracy. Crit Care Med. 2013;41 (7):1711–1718. doi:10.1097/CCM.0b013e31828a24fe
  • Knaus WA, Wagner DP, Draper EA, et al. The APACHE III prognostic system. Risk prediction of hospital mortality for critically ill hospitalized adults. Chest. 1991;100 (6):1619–1636. doi:10.1378/chest.100.6.1619
  • Spasovski G, Vanholder R, Allolio B, et al. Clinical practice guideline on diagnosis and treatment of hyponatraemia. Intensive Care Med. 2014;40 (3):320–331. doi:10.1007/s00134-014-3210-2
  • Qian Q. Hypernatremia. Clin J Am Soc Nephrol. 2019;14 (3):432–434. doi:10.2215/CJN.12141018
  • Chi C, Patel S, Cheung NW. Admission sodium levels and hospital outcomes. Intern Med J. 2021;51 (1):93–98. doi:10.1111/imj.14777
  • García-Sanz MT, Martínez-Gestoso S, Calvo-álvarez U, et al. Impact of hyponatremia on COPD exacerbation prognosis. J Clin Med. 2020;9 (2):503. doi:10.3390/jcm9020503
  • Chalela R, González-García JG, Chillarón JJ, et al. Impact of hyponatremia on mortality and morbidity in patients with COPD exacerbations. Respir Med. 2016;117:237–242. doi:10.1016/j.rmed.2016.05.003
  • Pokaharel M, Block CA. Dysnatremia in the ICU. Curr Opin Crit Care. 2011;17 (6):581–593. doi:10.1097/MCC.0b013e32834cd388
  • Oude Lansink-Hartgring A, Hessels L, Weigel J, et al. Long-term changes in dysnatremia incidence in the ICU: a shift from hyponatremia to hypernatremia. Ann Intensive Care. 2016;6 (1):22. doi:10.1186/s13613-016-0124-x
  • Ravioli S, Gygli R, Funk GC, et al. Prevalence and impact on outcome of sodium and potassium disorders in patients with community-acquired pneumonia: a retrospective analysis. Eur J Intern Med. 2021;85:63–67. doi:10.1016/j.ejim.2020.12.003
  • Atila C, Sailer CO, Bassetti S, et al. Prevalence and outcome of dysnatremia in patients with COVID-19 compared to controls. Eur J Endocrinol. 2021;184 (3):409–418. doi:10.1530/EJE-20-1374
  • Tzoulis P, Waung JA, Bagkeris E, et al. Dysnatremia is a predictor for morbidity and mortality in hospitalized patients with COVID-19. J Clin Endocrinol Metab. 2021;106 (6):1637–1648. doi:10.1210/clinem/dgab107
  • Bernardi M, Zaccherini G. Approach and management of dysnatremias in cirrhosis. Hepatol Int. 2018;12 (6):487–499. doi:10.1007/s12072-018-9894-6
  • Huang H, Jolly SE, Airy M, et al. Associations of dysnatremias with mortality in chronic kidney disease. Nephrol Dial Transplant. 2017;32 (7):1204–1210. doi:10.1093/ndt/gfw209
  • Sen S, Tran N, Chan B, et al. Sodium variability is associated with increased mortality in severe burn injury. Burns Trauma. 2017;5:34. doi:10.1186/s41038-017-0098-4
  • Darmon M, Diconne E, Souweine B, et al. Prognostic consequences of borderline dysnatremia: pay attention to minimal serum sodium change. Crit Care. 2013;17 (1):R12. doi:10.1186/cc11937
  • Martino M, Falcioni P, Giancola G, et al. Sodium alterations impair the prognosis of hospitalized patients with COVID-19 pneumonia. Endocr Connect. 2021;10 (10):1344–1351. doi:10.1530/EC-21-0411
  • Chen L, Liu C, Liu L. Osmolality-induced tuning of action potentials in trigeminal ganglion neurons. Neurosci Lett. 2009;452 (1):79–83. doi:10.1016/j.neulet.2009.01.022
  • Chen L, Liu C, Liu L, Cao X. Changes in osmolality modulate voltage-gated sodium channels in trigeminal ganglion neurons. Neurosci Res. 2009;64 (2):199–207. doi:10.1016/j.neures.2009.02.012
  • Becker D, Bereiter-Hahn J, Jendrach M. Functional interaction of the cation channel transient receptor potential vanilloid 4 (TRPV4) and actin in volume regulation. Eur J Cell Biol. 2009;88 (3):141–152. doi:10.1016/j.ejcb.2008.10.002
  • Vanhaebost J, Palmiere C, Scarpelli MP, et al. Postmortem diagnosis of hyponatremia: case report and literature review. Int J Legal Med. 2018;132 (1):173–179. doi:10.1007/s00414-017-1601-y
  • Urso C, Brucculeri S, Caimi G. Physiopathological, epidemiological, clinical and therapeutic aspects of exercise-associated hyponatremia. J Clin Med. 2014;3 (4):1258–1275. doi:10.3390/jcm3041258
  • Bihari S, Peake SL, Bailey M, et al. Admission high serum sodium is not associated with increased intensive care unit mortality risk in respiratory patients. J Crit Care. 2014;29 (6):948–954. doi:10.1016/j.jcrc.2014.06.008
  • Krüger S, Ewig S, Giersdorf S, et al. Dysnatremia, vasopressin, atrial natriuretic peptide and mortality in patients with community-acquired pneumonia: results from the German competence network CAPNETZ. Respir Med. 2014;108 (11):1696–1705. doi:10.1016/j.rmed.2014.09.014
  • Stewart AG, Waterhouse JC, Billings CG, et al. Hormonal, renal, and autonomic nerve factors involved in the excretion of sodium and water during dynamic salt and water loading in hypoxaemic chronic obstructive pulmonary disease. Thorax. 1995;50 (8):838–845. doi:10.1136/thx.50.8.838
  • Yagi T, Kaneko T, Tsuruta R, et al. Global end-diastolic volume, serum osmolarity, and albumin are risk factors for increased extravascular lung water. J Crit Care. 2011;26 (2):224.e9–13. doi:10.1016/j.jcrc.2010.07.011
  • Shen Y, Cheng X, Ying M, et al. Association between serum osmolarity and mortality in patients who are critically ill: a retrospective cohort study. BMJ Open. 2017;7 (5):e015729. doi:10.1136/bmjopen-2016-015729
  • Yu Y, Yu J, Yao R, et al. Admission serum ionized and total calcium as new predictors of mortality in patients with cardiogenic shock. Biomed Res Int. 2021;2021:6612276. doi:10.1155/2021/6612276
  • Yang J, Yang J. Association between blood eosinophils and mortality in critically ill patients with acute exacerbation of chronic obstructive pulmonary disease: a Retrospective Cohort Study. Int J Chron Obstruct Pulmon Dis. 2021;16:281–288. doi:10.2147/COPD.S289920
  • Zhu M, Dai L, Wan L, et al. Dynamic increase of red cell distribution width predicts increased risk of 30-day readmission in patients with acute exacerbation of chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2021;16:393–400. doi:10.2147/COPD.S291833
  • Kumar P, Law S, Sriram KB. Evaluation of platelet lymphocyte ratio and 90-day mortality in patients with acute exacerbation of chronic obstructive pulmonary disease. J Thorac Dis. 2017;9 (6):1509–1516. doi:10.21037/jtd.2017.05.77
  • Sakurai K, Chubachi S, Irie H, et al. Clinical utility of blood neutrophil-lymphocyte ratio in Japanese COPD patients. BMC Pulm Med. 2018;18 (1):65. doi:10.1186/s12890-018-0639-z