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ORIGINAL RESEARCH

A Multicenter Study of COPD and Cognitive Impairment: Unraveling the Interplay of Quantitative CT, Lung Function, HIF-1α, and Clinical Variables

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Pages 1741-1753 | Received 01 Mar 2024, Accepted 20 Jul 2024, Published online: 30 Jul 2024

References

  • GOLD Report - Global Initiative for Chronic Obstructive Lung Disease – GOLD. 2024; Available from:. https://goldcopd.org/2024-gold-report/. Accessed February 15, 2024
  • Siraj RA. Comorbid Cognitive Impairment in Chronic Obstructive Pulmonary Disease (COPD): current Understanding, Risk Factors, Implications for Clinical Practice, and Suggested Interventions. Medicina. 2023;59(4). doi:10.3390/medicina59040732
  • Thaipisuttikul P, Jaikla K, Satthong S, et al. Rate of conversion from mild cognitive impairment to dementia in a Thai hospital-based population: a retrospective cohort. Alzheimer's Dementia. 2022;8(1)
  • Rong B, Liu Y, Li M, Fu T, Gao W, Liu H. Correlation of serum levels of HIF-1α and IL-19 with the disease progression of COPD: a retrospective study. Int J Chron Obstruct Pulmon Dis. 2018;13:3791–3803. doi:10.2147/COPD.S177034
  • Dodd JW. Lung disease as a determinant of cognitive decline and dementia. Alzheimers Res Ther. 2015;7(1). doi:10.1186/s13195-015-0116-3
  • Li J, Huang Y, Fei GH. The evaluation of cognitive impairment and relevant factors in patients with chronic obstructive pulmonary disease. Respiration. 2013;85(2):98–105. doi:10.1159/000342970
  • Dodd JW, Getov SV, Jones PW. Cognitive function in COPD. Eur Respir J. 2010;35(4):913–922. doi:10.1183/09031936.00125109
  • Kurashima K, Fukuda C, Nakamoto K, et al. CT-diagnosed emphysema and prognosis of chronic airflow obstruction: a retrospective study. BMJ Open. 2013;3(11):3541. doi:10.1136/bmjopen-2013-003541
  • Han MLK, Kazerooni EA, Lynch DA, et al. Chronic obstructive pulmonary disease exacerbations in the COPDGene study: associated radiologic phenotypes. Radiology. 2011;261(1):274–282. doi:10.1148/radiol.11110173
  • Fernandes L, Fernandes Y, Mesquita A. Quantitative computed tomography imaging in chronic obstructive pulmonary disease. Lung India. 2016;33(6):646. doi:10.4103/0970-2113.192880
  • Schroeder JD, McKenzie AS, Zach JA, et al. Relationships between airflow obstruction and quantitative CT measurements of emphysema, air trapping, and airways in subjects with and without chronic obstructive pulmonary disease. AJR Am J Roentgenol. 2013;201(3):W460–W470. doi:10.2214/AJR.12.10102
  • Bak SH, Kwon SO, Han SS, et al. Computed tomography-derived area and density of pectoralis muscle associated disease severity and longitudinal changes in chronic obstructive pulmonary disease: a case control study. Respir Res. 2019;20(1). doi:10.1186/s12931-019-1191-y
  • Wells JM, Washko GR, Han MK, et al. Pulmonary arterial enlargement and acute exacerbations of COPD. N Engl J Med. 2012;367(10):913–921. doi:10.1056/NEJMoa1203830
  • McDonald MLN, Diaz AA, Ross JC, et al. Quantitative computed tomography measures of pectoralis muscle area and disease severity in chronic obstructive pulmonary disease. A cross-sectional study. Ann Am Thorac Soc. 2014;11(3):326–334. doi:10.1513/AnnalsATS.201307-229OC
  • Graham BL, Steenbruggen I, Barjaktarevic IZ, et al. Standardization of Spirometry 2019 UpdateAn Official American Thoracic Society and European Respiratory Society Technical Statement. Am J Respir Crit Care Med. 2019;200(8):E70–E88.
  • Yamashiro T, Matsuoka S, San José Estépar R, et al. Quantitative assessment of bronchial wall attenuation with thin-section CT: an indicator of airflow limitation in chronic obstructive pulmonary disease. AJR Am J Roentgenol. 2010;195(2):363–369. doi:10.2214/AJR.09.3653
  • Takayanagi T, Suzuki S, Katada Y, et al. Comparison of Motion Artifacts on CT Images Obtained in the Ultrafast Scan Mode and Conventional Scan Mode for Unconscious Patients in the Emergency Department. AJR Am J Roentgenol. 2019;213(4):153–161. doi:10.2214/AJR.19.21456
  • Dudurych I, Muiser S, McVeigh N, et al. Bronchial wall parameters on CT in healthy never-smoking, smoking, COPD, and asthma populations: a systematic review and meta-analysis. Eur Radiol. 2022;32(8):5308. doi:10.1007/s00330-022-08600-1
  • Koyama H, Ohno Y, Nishio M, et al. Three-dimensional airway lumen volumetry: comparison with bronchial wall area and parenchymal densitometry in assessment of airway obstruction in pulmonary emphysema. Br J Radiol. 2012;85(1020):1525. doi:10.1259/bjr/22602417
  • Nakano Y, Wong JC, De Jong PA, et al. The prediction of small airway dimensions using computed tomography. Am J Respir Crit Care Med. 2005;171(2):142–146. doi:10.1164/rccm.200407-874OC
  • Schneider M, Ran H, Pistritto AM, et al. Pulmonary artery to ascending aorta ratio by echocardiography: a strong predictor for presence and severity of pulmonary hypertension. PLoS One. 2020;15(7):e0235716. doi:10.1371/journal.pone.0235716
  • Malenfant S, Brassard P, Paquette M, et al. Compromised Cerebrovascular Regulation and Cerebral Oxygenation in Pulmonary Arterial Hypertension. J Am Heart Assoc. 2017;6(10). doi:10.1161/JAHA.117.006126
  • Wu XG, Shi YJ, Wang XH, et al. Diagnostic value of computed tomography‐based pulmonary artery to aorta ratio measurement in chronic obstructive pulmonary disease with pulmonary hypertension: a systematic review and meta‐analysis. Clin Respir J. 2022;16(4):276–283. doi:10.1111/crj.13485
  • Sun R, Ge B, Wu S, et al. Optimal cut-off MoCA score for screening for mild cognitive impairment in elderly individuals in China: a systematic review and meta-analysis. Asian J Psychiatr. 2023;87:103691. doi:10.1016/j.ajp.2023.103691
  • Valenzuela MJ, Sachdev P. Brain reserve and cognitive decline: a non-parametric systematic review. Psychol Med. 2006;36(8):1065–1073. doi:10.1017/S0033291706007744
  • Meng X, D’Arcy C, Laks J. Education and Dementia in the Context of the Cognitive Reserve Hypothesis: a Systematic Review with Meta-Analyses and Qualitative Analyses. PLoS One. 2012;7(6). doi:10.1371/journal.pone.0038268
  • Clouston SAP, Smith DM, Mukherjee S, et al. Education and Cognitive Decline: an Integrative Analysis of Global Longitudinal Studies of Cognitive Aging. J Gerontol B Psychol Sci Soc Sci. 2020;75(7):E151–E160. doi:10.1093/geronb/gbz053
  • Sun Y, Milne S, Jaw JE, et al. BMI is associated with FEV1 decline in chronic obstructive pulmonary disease: a meta-analysis of clinical trials. Respir Res. 2019;20(1):1–10. doi:10.1186/s12931-019-1209-5
  • Mun YS, Park HK, Kim J, et al. Association Between Body Mass Index and Cognitive Function in Mild Cognitive Impairment Regardless of APOE ε4 Status. Dement Neurocogn Disord. 2022;21(1):30. doi:10.12779/dnd.2022.21.1.30
  • Qu Y, Hu HY, Ou YN, et al. Association of body mass index with risk of cognitive impairment and dementia: a systematic review and meta-analysis of prospective studies. Neurosci Biobehav Rev. 2020;115:189–198. doi:10.1016/j.neubiorev.2020.05.012
  • Puzianowska-Kuznicka M, Kuryłowicz A, Walkiewicz D, et al. Obesity Paradox in Caucasian Seniors: results of the PolSenior Study. J Nutr Health Aging. 2019;23(9):796–804. doi:10.1007/s12603-019-1257-z
  • Konietzke P, Wielpütz MO, Wagner WL, et al. Quantitative CT detects progression in COPD patients with severe emphysema in a 3-month interval. Eur Radiol. 2020;30(5):2502–2512. doi:10.1007/s00330-019-06577-y
  • Martini K, Frauenfelder T. Emphysema and lung volume reduction: the role of radiology. J Thorac Dis. 2018;10(Suppl 23):S2719–S2731. doi:10.21037/jtd.2018.05.117
  • Harmouche R, Ross JC, Diaz AA, et al. A Robust Emphysema Severity Measure Based on Disease Subtypes. Acad Radiol. 2016;23(4):421–428. doi:10.1016/j.acra.2015.12.021
  • Mizusawa H, Shiraishi O, Shiraishi M, et al. Quantitative emphysema on computed tomography imaging of chest is a risk factor for prognosis of esophagectomy: a retrospective cohort study. Medicine. 2023;102(41):E35547.
  • Knudsen L, Ochs M. The micromechanics of lung alveoli: structure and function of surfactant and tissue components. Histochem Cell Biol. 2018;150(6):661–676. doi:10.1007/s00418-018-1747-9
  • Martinez CH, Richardson CR, Han MLK, et al. Chronic obstructive pulmonary disease, cognitive impairment, and development of disability: the health and retirement study. Ann Am Thorac Soc. 2014;11(9):1362–1370. doi:10.1513/AnnalsATS.201405-187OC
  • Maclay JD, McAllister DA, Rabinovich R, et al. Systemic elastin degradation in chronic obstructive pulmonary disease. Thorax. 2012;67(7):606–612. doi:10.1136/thoraxjnl-2011-200949
  • Ginouvès A, Ilc K, Macías N, et al. PHDs overactivation during chronic hypoxia “desensitizes” HIFα and protects cells from necrosis. Proc Natl Acad Sci U S A. 2008;105(12):4745–4750. doi:10.1073/pnas.0705680105
  • Jaśkiewicz M, Moszyńska A, Króliczewski J, et al. The transition from HIF-1 to HIF-2 during prolonged hypoxia results from reactivation of PHDs and HIF1A mRNA instability. Cell Mol Biol Lett. 2022;27(1):1–19. doi:10.1186/s11658-022-00408-7
  • Yasuo M, Mizuno S, Kraskauskas D, et al. Hypoxia inducible factor-1α in human emphysema lung tissue. Eur Respir J. 2011;37(4):775–783. doi:10.1183/09031936.00022910
  • To M, Yamamura S, Akashi K, et al. Defect of adaptation to hypoxia in patients with COPD due to reduction of histone deacetylase 7. Chest. 2012;141(5):1233–1242. doi:10.1378/chest.11-1536
  • Fard MT, Cribb L, Nolidin K, Savage K, Wesnes K, Stough C. Is there a relationship between low-grade systemic inflammation and cognition in healthy people aged 60-75 years? Behav Brain Res. 2020;383.
  • Dyer AH, McNulty H, Caffrey A, et al. Low-Grade systemic inflammation is associated with domain-specific cognitive performance and cognitive decline in older adults: data from the TUDA study. Neurobiol Aging. 2024;134:94–105. doi:10.1016/j.neurobiolaging.2023.11.008
  • Kipinoinen T, Toppala S, Rinne JO, et al. Association of Midlife Inflammatory Markers with Cognitive Performance at 10-Year Follow-up. Neurology. 2022;99(20):E2294–E2302. doi:10.1212/WNL.0000000000201116