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Review

Distinguishing adult-onset asthma from COPD: a review and a new approach

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Pages 945-962 | Published online: 09 Sep 2014

References

  • BurgessJAMathesonMCGurrinLCFactors influencing asthma remission: a longitudinal study from childhood to middle ageThorax201166650851321450787
  • PavordIDNon-eosinophilic asthma and the innate immune responseThorax200762319319417329554
  • SvanesCSunyerJPlanaEEarly life origins of chronic obstructive pulmonary diseaseThorax2010651142019729360
  • Global Initiative for Asthma [homepage on the Internet]Global Strategy for Asthma Management and Prevention2011 Available from: http://www.ginasthma.org/GINA-Report,-Global-Strategy-for-Asthma-Management-and-PreventionAccessed March 21, 2014
  • PauwelsRABuistASCalverleyPMJenkinsCRHurdSSGOLD Scientific CommitteeGlobal strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summaryAm J Respir Crit Care Med200116351256127611316667
  • RabeKFHurdSAnzuetoAGlobal Initiative for Chronic Obstructive Lung DiseaseGlobal strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summaryAm J Respir Crit Care Med2007176653255517507545
  • MarshSETraversJWeatherallMProportional classifications of COPD phenotypesThorax200863976176718728201
  • GibsonPGSimpsonJLThe overlap syndrome of asthma and COPD: what are its features and how important is it?Thorax200964872873519638566
  • GuerraSAsthma and chronic obstructive pulmonary diseaseCurr Opin Allergy Clin Immunol20099540941619638929
  • GibsonPGMcDonaldVMMarksGBAsthma in the older adultsLancet2010374974380381320816547
  • McDonaldVMHigginsIGibsonPGManaging older patients with coexistent asthma and chronic obstructive pulmonary disease: diagnostic and therapeutic challengesDrugs Aging201330111723229768
  • BuistASMcBurnieMAVollmerWMBOLD Collaborative Research GroupInternational variation in the prevalence of COPD (the BOLD Study): a population-based prevalence studyLancet2007370958974175017765523
  • MasoliMFabianDHoltSBeasleyRGlobal Initiative for Asthma (GINA) ProgramThe global burden of asthma: executive summary of the GINA Dissemination Committee reportAllergy200459546947815080825
  • de NijsSBVenekampLNBelEHAdult-onset asthma: is it really different?Eur Respir Rev201322127445223457164
  • National Heart Lung and Blood Institute [homepage on the Internet]Morbidity and Mortality: 2012 Chart Book on Cardiovascular, Lung and Blood Diseases; 2012 [updated 2013]Washington, DCNational Institutes of Health, US Department of Health and Human Services Available from: http://www.nhlbi.nih.gov/resources/docs/cht-book.htmAccessed March 21, 2014
  • McDonaldVMGibsonPGAsthma mortality and management in older Australians: time for a new approach?Australas J Ageing200827421519032626
  • Australian Centre for Asthma MonitoringAsthma in Australia 2011: with a focus chapter on chronic obstructive pulmonary disease [webpage on the Internet]CanberraAustralian Institute of Health and Welfare2011 Available from: http://www.aihw.gov.au/publication-detail/?id=10737420159Accessed May 9, 2014
  • BurneyPChinnSJarvisDLuczynskaCLaiEEuropean Community Respiratory Health SurveyVariations in the prevalence of respiratory symptoms, self-reported asthma attacks, and use of asthma medication in the European Community Respiratory Health Survey (ECRHS)Eur Respir J1996946876958726932
  • LopezADMathersCDEzzatiMJamisonDTMurrayCJGlobal and regional burden of disease and risk factors, 2001: systematic analysis of population health dataLancet200636795241747175716731270
  • RycroftCEHeyesALanzaLBeckerKEpidemiology of chronic obstructive pulmonary disease: a literature reviewInt J Chron Obstruct Pulmon Dis2012745749422927753
  • Global strategy for the diagnosis, management, and prevention of COPD [webpage on the Internet]Global Initiative for Chronic Obstructive Lung Disease2014 Available from: http://www.goldcopd.org/guidelines-global-strategy-for-diagnosis-management.htmlAccessed March 21, 2014
  • PunekarYSShuklaAMüllerovaHCOPD management costs according to the frequency of COPD exacerbations in UK primary careInt J Chron Obstruct Pulmon Dis20149657324426781
  • CisternasMGBlancPDYenIHA comprehensive study of the direct and indirect costs of adult asthmaJ Allergy Clin Immunol200311161212121812789219
  • TorénKHermanssonBAIncidence rate of adult-onset asthma in relation to age, sex, atopy and smoking: a Swedish population-based study of 15813 adultsInt J Tuberc Lung Dis19993319219710094318
  • ToelleBGPeatJKSalomeCMMellisCMWoolcockAJToward a definition of asthma for epidemiologyAm Rev Respir Dis199214636336371519839
  • ZhangXMorrison-CarpenterTHoltJBCallahanDBTrends in adult current asthma prevalence and contributing risk factors in the United States by state: 2000–2009BMC Public Health201313115624325173
  • PearceNAït-KhaledNBeasleyRISAAC Phase Three Study GroupWorldwide trends in the prevalence of asthma symptoms: phase III of the International Study of Asthma and Allergies in Childhood (ISAAC)Thorax200762975876617504817
  • McHughMKSymanskiEPompeiiLADelclosGLPrevalence of asthma among adult females and males in the United States: results from the National Health and Nutrition Examination Survey (NHANES), 2001–2004J Asthma200946875976619863277
  • ToelleBGXuanWBirdTERespiratory symptoms and illness in older Australians: the Burden of Obstructive Lung Disease (BOLD) studyMed J Aust2013198314414823418694
  • MolloyKHershCPMorrisVBClarification of the risk of chronic obstructive pulmonary disease in α1-antitrypsin deficiency PiMZ heterozygotesAm J Respir Crit Care Med2014189441942724428606
  • HnizdoEGlindmeyerHWPetsonkELEnrightPBuistASCase definitions for chronic obstructive pulmonary diseaseCOPD2006329510017175672
  • QuanjerPHPrettoJJBrazzaleDJBorosPWGrading the severity of airways obstruction: new wine in new bottlesEur Respir J201443250551223988764
  • MehtaAThunGAImbodenMSERPINA1 PiMZ genotype, environmental and occupational exposure, and change in lung functionPaper presented at: ISEE Environment and HealthAugust 19–23, 2013Basel, Switzerland
  • SternDAMorganWJHalonenMWrightALMartinezFDWheezing and bronchial hyper-responsiveness in early childhood as predictors of newly diagnosed asthma in early adulthood: a longitudinal birth-cohort studyLancet200837296431058106418805334
  • StocksJHislopASonnappaSEarly lung development: lifelong effect on respiratory health and diseaseLancet Respir Med20131972874224429276
  • GaudermanWJVoraHMcConnellREffect of exposure to traffic on lung development from 10 to 18 years of age: a cohort studyLancet2007369956157157717307103
  • LandauLITobacco smoke exposure and tracking of lung function into adult lifePaediatr Respir Rev2008913943 quiz 4318280978
  • GaudermanWJAvolEGillilandFThe effect of air pollution on lung development from 10 to 18 years of ageN Engl J Med2004351111057106715356303
  • GillilandFDBerhaneKLiYFRappaportEBPetersJMEffects of early onset asthma and in utero exposure to maternal smoking on childhood lung functionAm J Respir Crit Care Med2003167691792412480608
  • JamrozikEKnuimanMWJamesADivitiniMMuskAWRisk factors for adult-onset asthma: a 14-year longitudinal studyRespirology200914681482119703063
  • HoyRFBurgessJABenkeGOccupational exposures and the development of new-onset asthma: a population-based cohort study from the ages of 13 to 44 yearsJ Occup Environ Med201355323523923439266
  • BlancPDIribarrenCTrupinLOccupational exposures and the risk of COPD: dusty trades revisitedThorax200964161218678700
  • SvanesCWhat has the ECRHS told us about the childhood risks of asthma, allergy and lung function?Clin Respir J20082Suppl 1344420298348
  • JenkinsMADharmageSCFlanderLBParity and decreased use of oral contraceptives as predictors of asthma in young womenClin Exp Allergy200636560961316650045
  • RealFGSvanesCOmenaasERLung function, respiratory symptoms, and the menopausal transitionJ Allergy Clin Immunol200812117280. e318028993
  • RomieuIFabreAFournierAPostmenopausal hormone therapy and asthma onset in the E3N cohortThorax201065429229720142267
  • PoJYFitzGeraldJMCarlstenCRespiratory disease associated with solid biomass fuel exposure in rural women and children: systematic review and meta-analysisThorax201166323223921248322
  • KurmiOPSempleSSimkhadaPSmithWCAyresJGCOPD and chronic bronchitis risk of indoor air pollution from solid fuel: a systematic review and meta-analysisThorax201065322122820335290
  • EisnerMDAnthonisenNCoultasDCommittee on Nonsmoking COPD, Environmental and Occupational Health AssemblyAn official American Thoracic Society public policy statement: Novel risk factors and the global burden of chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2010182569371820802169
  • DimakopoulouKSamoliEBeelenRAir pollution and nonmalignant respiratory mortality in 16 cohorts within the ESCAPE projectAm J Respir Crit Care Med2014189668469624521254
  • McCreanorJCullinanPNieuwenhuijsenMJRespiratory effects of exposure to diesel traffic in persons with asthmaN Engl J Med2007357232348235818057337
  • BalmesJREarnestGKatzPPExposure to traffic: lung function and health status in adults with asthmaJ Allergy Clin Immunol2009123362663119152968
  • BarnesPJThe cytokine network in asthma and chronic obstructive pulmonary diseaseJ Clin Invest2008118113546355618982161
  • BroekemaMTimensWVonkJMPersisting remodeling and less airway wall eosinophil activation in complete remission of asthmaAm J Respir Crit Care Med2011183331031620813885
  • SorianoJBDavisKJColemanBVisickGManninoDPrideNBThe proportional Venn diagram of obstructive lung disease: two approximations from the United States and the United KingdomChest2003124247448112907531
  • WeatherallMTraversJShirtcliffePMDistinct clinical phenotypes of airways disease defined by cluster analysisEur Respir J200934481281819357143
  • PirasBMiravitllesMThe overlap phenotype: the (missing) link between asthma and COPDMultidiscip Respir Med201271822958436
  • RutgersSRPostmaDSten HackenNHOngoing airway inflammation in patients with COPD who do not currently smokeThorax2000551121810607796
  • BarnesPJImmunology of asthma and chronic obstructive pulmonary diseaseNat Rev Immunol20088318319218274560
  • BarnesPJCelliBRSystemic manifestations and comorbidities of COPDEur Respir J20093351165118519407051
  • SindenNJStockleyRASystemic inflammation and comorbidity in COPD: a result of ‘overspill’ of inflammatory mediators from the lungs? Review of the evidenceThorax2010651093093620627907
  • MiravitllesMSoler-CataluñaJJCalleMA new approach to grading and treating COPD based on clinical phenotypes: summary of the Spanish COPD guidelines (GesEPOC)Prim Care Respir J201322111712123443227
  • MirandaCBusackerABalzarSTrudeauJWenzelSEDistinguishing severe asthma phenotypes: role of age at onset and eosinophilic inflammationJ Allergy Clin Immunol2004113110110814713914
  • TaiATranHRobertsMOutcomes of childhood asthma to the age of 50 yearsJ Allergy Clin Immunol2014133615721578. e324495434
  • PerretJLDharmageSCMathesonMCThe interplay between the effects of lifetime asthma, smoking, and atopy on fixed airflow obstruction in middle ageAm J Respir Crit Care Med20131871424823155143
  • JamesALKnuimanMWDivitiniMLChanges in the prevalence of asthma in adults since 1966: the Busselton health studyEur Respir J201035227327819643935
  • HaldarPPavordIDNoneosinophilic asthma: a distinct clinical and pathologic phenotypeJ Allergy Clin Immunol2007119510431052 quiz 105317472810
  • PhelanPDThe natural history of asthma from childhood to adult lifeWallsRSJenkinsCRUnderstanding Asthma. A Management CompanionEastgardens, NSWMacLennan and Petty20002025
  • BurgessJAWaltersEHByrnesGBWho remembers whether they had asthma as children?J Asthma2006431072773017169822
  • VestboJEdwardsLDScanlonPDECLIPSE InvestigatorsChanges in forced expiratory volume in 1 second over time in COPDN Engl J Med2011365131184119221991892
  • SorianoJBVisickGTMuellerovaHPayvandiNHansellALPatterns of comorbidities in newly diagnosed COPD and asthma in primary careChest200512842099210716236861
  • ZvezdinBMilutinovSKojicicMA postmortem analysis of major causes of early death in patients hospitalized with COPD exacerbationChest2009136237638019318666
  • ArnsonYShoenfeldYAmitalHEffects of tobacco smoke on immunity, inflammation and autoimmunityJ Autoimmun2010343J258J26520042314
  • ShaabanRKonySDrissFChange in C-reactive protein levels and FEV1 decline: a longitudinal population-based studyRespir Med2006100122112212016650972
  • SinDDManSFWhy are patients with chronic obstructive pulmonary disease at increased risk of cardiovascular diseases? The potential role of systemic inflammation in chronic obstructive pulmonary diseaseCirculation2003107111514151912654609
  • WeinerPMagadleRWaizmanJWeinerMRabnerMZamirDCharacteristics of asthma in the elderlyEur Respir J19981235645689762780
  • GoemanDPDouglassJAUnderstanding asthma in older Australians: a qualitative approachMed J Aust2005183Suppl 1S26S2715992317
  • KingPTHoldsworthSRFreezerNJVillanuevaEGallagherMHolmesPWOutcome in adult bronchiectasisCOPD200521273417136958
  • PatelISVlahosIWilkinsonTMBronchiectasis, exacerbation indices, and inflammation in chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2004170440040715130905
  • Martínez-GarcíaMAde la Rosa CarrilloDSoler-CataluñaJJPrognostic value of bronchiectasis in patients with moderate-to-severe chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2013187882383123392438
  • PangJChanHSSungJYPrevalence of asthma, atopy, and bronchial hyperreactivity in bronchiectasis: a controlled studyThorax198944119489512595637
  • PellegrinoRViegiGBrusascoVInterpretative strategies for lung function testsEur Respir J200526594896816264058
  • TashkinDPCelliBDecramerMBronchodilator responsiveness in patients with COPDEur Respir J200831474275018256071
  • VonkJMJongepierHPanhuysenCISchoutenJPBleeckerERPostmaDSRisk factors associated with the presence of irreversible airflow limitation and reduced transfer coefficient in patients with asthma after 26 years of follow upThorax200358432232712668795
  • O’ByrnePMInmanMDAirway hyperresponsivenessChest2003123Suppl 3411S416S12629006
  • JuniperEFFrithPAHargreaveFEAirway responsiveness to histamine and methacholine: relationship to minimum treatment to control symptoms of asthmaThorax19813685755797031972
  • ScichiloneNMessinaMBattagliaSCatalanoFBelliaVAirway hyperresponsiveness in the elderly: prevalence and clinical implicationsEur Respir J200525236437515684304
  • TashkinDPAltoseMDConnettJEKannerRELeeWWWiseRAMethacholine reactivity predicts changes in lung function over time in smokers with early chronic obstructive pulmonary disease. The Lung Health Study Research GroupAm J Respir Crit Care Med19961536 Pt 1180218118665038
  • The COPD-X Plan. Australian and New Zealand Guidelines for the management of Chronic Obstructive Pulmonary Disease 2013 [web-page on the Internet]Lung FoundationAustralia2013 Available from: http://www.copdx.org.au/Accessed July 25, 2014
  • CummingGHuntLBForm and function in the human lung: Proceedings of a Symposium held in the University of Birmingham, Birmingham, UK, 5–7 April 1967Edinburgh, ScotlandE & S Livingstone Ltd1968
  • JohannessenASkorgeTDBottaiMMortality by level of emphysema and airway wall thicknessAm J Respir Crit Care Med2013187660260823328525
  • FattahiFten HackenNHLöfdahlCGAtopy is a risk factor for respiratory symptoms in COPD patients: results from the EUROSCOP studyRespir Res2013141023356508
  • ShaabanRZureikMSoussanDRhinitis and onset of asthma: a longitudinal population-based studyLancet200837296431049105718805333
  • CalverleyPMBurgePSSpencerSAndersonJAJonesPWBronchodilator reversibility testing in chronic obstructive pulmonary diseaseThorax200358865966412885978
  • ReidDWSoltaniAJohnsDPBronchodilator reversibility in Australian adults with chronic obstructive pulmonary diseaseIntern Med J2003331257257714656230
  • McDonaldVMSimpsonJLHigginsIGibsonPGMultidimensional assessment of older people with asthma and COPD: clinical management and health statusAge Ageing2011401424921087988
  • PavordIDGibsonPGInflammometry: the current state of playThorax201267319119222344396
  • NairPUpdate on clinical inflammometry for the management of airway diseasesCan Respir J201320211712023616969
  • SalviSSBarnesPJChronic obstructive pulmonary disease in non-smokersLancet2009374969173374319716966
  • VozorisNTStanbrookMBSmoking prevalence, behaviours, and cessation among individuals with COPD or asthmaRespir Med2011105347748420850288
  • D’SilvaLHassanNWangHYHeterogeneity of bronchitis in airway diseases in tertiary care clinical practiceCan Respir J201118314414821766077
  • SimpsonJLScottRBoyleMJGibsonPGInflammatory subtypes in asthma: assessment and identification using induced sputumRespirology2006111546116423202
  • FuJJGibsonPGSimpsonJLMcDonaldVMLongitudinal changes in clinical outcomes in older patients with asthma, COPD and asthma-COPD overlap syndromeRespiration2014871637424029561
  • HardinMSilvermanEKBarrRGCOPDGene InvestigatorsThe clinical features of the overlap between COPD and asthmaRespir Res20111212721951550
  • GonemSRajVWardlawAJPavordIDGreenRSiddiquiSPhenotyping airways disease: an A to E approachClin Exp Allergy201242121664168323181785
  • BainesKJSimpsonJLWoodLGScottRJGibsonPGInduced sputum differential gene expression implicates increased p38 signalling activity in severe asthmaPaper presented at: Annual Meeting of the European Respiratory Society CongressSeptember 24–28, 2011Amsterdam, Netherlands
  • McDonaldVMHigginsIWoodLGGibsonPGMultidimensional assessment and tailored interventions for COPD: respiratory utopia or common sense?Thorax201368769169423503624
  • PavordIDComplex airway disease: an approach to assessment and managementLancet Respir Med201311849024321807
  • GreenRHBrightlingCEMcKennaSAsthma exacerbations and sputum eosinophil counts: a randomised controlled trialLancet200236093471715172112480423
  • JayaramLPizzichiniMMCookRJDetermining asthma treatment by monitoring sputum cell counts: effect on exacerbationsEur Respir J200627348349416507847
  • SivaRGreenRHBrightlingCEEosinophilic airway inflammation and exacerbations of COPD: a randomised controlled trialEur Respir J200729590691317301099
  • PetskyHLCatesCJLassersonTJA systematic review and meta-analysis: tailoring asthma treatment on eosinophilic markers (exhaled nitric oxide or sputum eosinophils)Thorax201267319920820937641
  • BainesKJSimpsonJLWoodLGScottRJGibsonPGTranscriptional phenotypes of asthma defined by gene expression profiling of induced sputum samplesJ Allergy Clin Immunol20111271153160 160.e1–e921211650
  • GorskaKKrenkeRKorczynskiPKosciuchJDomagala-KulawikJChazanREosinophilic airway inflammation in chronic obstructive pulmonary disease and asthmaJ Physiol Pharmacol200859Suppl 626127019218650
  • McDonaldVMGibsonPGExacerbations of severe asthmaClin Exp Allergy201242567067722515389
  • National Asthma Council AustraliaAustralian asthma handbook, Version 1.0MelbourneNational Asthma Council Australia2014 Available from: http://www.asthmahandbook.org.auAccessed March 20, 2014
  • ChapmanKRLoveLBrubakerHA comparison of breath-actuated and conventional metered-dose inhaler inhalation techniques in elderly subjectsChest19931045133213378222783
  • ConnollyMJInhaler technique of elderly patients: comparison of metered-dose inhalers and large volume spacer devicesAge Ageing19952431901927645436
  • BarronsRPegramABorriesAInhaler device selection: special considerations in elderly patients with chronic obstructive pulmonary diseaseAm J Health Syst Pharm201168131221123221690428
  • SovaniMPWhaleCIOborneJPoor adherence with inhaled corticosteroids for asthma: can using a single inhaler containing budesonide and formoterol help?Br J Gen Pract200858546374318186995
  • KewKMKarnerCMindusSMFerraraGCombination formoterol and budesonide as maintenance and reliever therapy versus combination inhaler maintenance for chronic asthma in adults and childrenCochrane Database Syst Rev201312CD00901924343671
  • CalverleyPMAndersonJACelliBTORCH investigatorsSalmeterol and fluticasone propionate and survival in chronic obstructive pulmonary diseaseN Engl J Med2007356877578917314337
  • SinghSLokeYKRisk of pneumonia associated with long-term use of inhaled corticosteroids in chronic obstructive pulmonary disease: a critical review and updateCurr Opin Pulm Med201016211812219926996
  • ManserRReidDAbramsonMJCorticosteroids for acute severe asthma in hospitalised patientsCochrane Database Syst Rev20011CD00174011279726
  • WaltersJAGibsonPGWood-BakerRHannayMWaltersEHSystemic corticosteroids for acute exacerbations of chronic obstructive pulmonary diseaseCochrane Database Syst Rev20091CD00128819160195
  • LeuppiJDSchuetzPBingisserRShort-term vs conventional glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease: the REDUCE randomized clinical trialJAMA2013309212223223123695200
  • McDonoughAKCurtisJRSaagKGThe epidemiology of glucocorticoid-associated adverse eventsCurr Opin Rheumatol200820213113718349741
  • GibsonPGPowellHCoughlanJSelf-management education and regular practitioner review for adults with asthmaCochrane Database Syst Rev20031CD00111712535399
  • AbramsonMJBaileyMJCouperFJVictorian Asthma Mortality Study GroupAre asthma medications and management related to deaths from asthmaAm J Respir Crit Care Med20011631121811208619
  • ZwerinkMBrusse-KeizerMvan der ValkPDSelf management for patients with chronic obstructive pulmonary diseaseCochrane Database Syst Rev20143CD00299024665053
  • WaltersJATurnockACWaltersEHWood-BakerRAction plans with limited patient education only for exacerbations of chronic obstructive pulmonary diseaseCochrane Database Syst Rev20105CD00507420464737
  • FriedlanderALLynchDDyarLABowlerRPPhenotypes of chronic obstructive pulmonary diseaseCOPD20074435538418027163
  • AgustiACalverleyPMCelliBEvaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigatorsCharacterisation of COPD heterogeneity in the ECLIPSE cohortRespir Res20101112220831787
  • NadeemNJTaylorSJEldridgeSMWithdrawal of inhaled corticosteroids in individuals with COPD – a systematic review and comment on trial methodologyRespir Res20111210721838890
  • MagnussenHWatzHKirstenAStepwise withdrawal of inhaled corticosteroids in COPD patients receiving dual bronchodilation: WISDOM study design and rationaleRespir Med2014108459359924477080
  • National Asthma Council AustraliaAsthma Management Handbook 2006MelbourneNational Asthma Council Australia2006 Available from: http://www.nationalasthma.org.au/uploads/handbook/370-amh2006_web_5.pdfAccessed March 20, 2014
  • ChauhanBFDucharmeFMAnti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and childrenCochrane Database Syst Rev20125CD00231422592685
  • NormansellRWalkerSMilanSJWaltersEHNairPOmalizumab for asthma in adults and childrenCochrane Database Syst Rev20141CD00355924414989
  • HaldarPBrightlingCEHargadonBMepolizumab and exacerbations of refractory eosinophilic asthmaN Engl J Med20093601097398419264686
  • McDonaldVMVertiganAEGibsonPGHow to set up a severe asthma serviceRespirology201116690091121692918
  • SteadLFHartmann-BoyceJPereraRLancasterTTelephone counselling for smoking cessationCochrane Database Syst Rev20138CD00285023934971
  • SteadLFPereraRBullenCNicotine replacement therapy for smoking cessationCochrane Database Syst Rev201211CD00014623152200
  • HughesJRSteadLFHartmann-BoyceJCahillKLancasterTAntidepressants for smoking cessationCochrane Database Syst Rev20141CD00003124402784
  • CahillKSteadLFLancasterTNicotine receptor partial agonists for smoking cessationCochrane Database Syst Rev20124CD00610322513936
  • SteadLFLancasterTBehavioural interventions as adjuncts to pharmacotherapy for smoking cessationCochrane Database Syst Rev201212CD00967023235680
  • ThomasDAbramsonMJBonevskiBA pharmacist-led system-change smoking cessation intervention for smokers admitted to Australian public hospitals (GIVE UP FOR GOOD): study protocol for a randomised controlled trialTrials20131414823693155
  • YohannesAMWillgossTGVestboJTiotropium for treatment of stable COPD: a meta-analysis of clinically relevant outcomesRespir Care201156447748721255503
  • VogelmeierCHedererBGlaabTPOET-COPD InvestigatorsTiotropium versus salmeterol for the prevention of exacerbations of COPDN Engl J Med2011364121093110321428765
  • TashkinDPCelliBSennSUPLIFT Study InvestigatorsA 4-year trial of tiotropium in chronic obstructive pulmonary diseaseN Engl J Med2008359151543155418836213
  • KestenSJaraMWentworthCLanesSPooled clinical trial analysis of tiotropium safetyChest200613061695170317166984
  • KerstjensHAEngelMDahlRTiotropium in asthma poorly controlled with standard combination therapyN Engl J Med2012367131198120722938706
  • BefekaduEOnofreiCColiceGLTiotropium in asthma: a systematic reviewJ Asthma Allergy20147112124600237
  • LacasseYBrosseauLMilnePulmonary rehabilitation for chronic obstructive pulmonary diseaseCochrane Database Syst Rev20023CD003793 [updated in Cochrane Database Syst Rev. 2006;4: CD003793]12137716
  • GriffithsTLBurrMLCampbellIAResults at 1 year of outpatient multidisciplinary pulmonary rehabilitation: a randomised controlled trialLancet2000355920136236810665556
  • GriffithsTLPhillipsCJDaviesSBurrMLCampbellIACost effectiveness of an outpatient multidisciplinary pulmonary rehabilitation programmeThorax2001561077978411562517
  • TurnerSEastwoodPCookAJenkinsSImprovements in symptoms and quality of life following exercise training in older adults with moderate/severe persistent asthmaRespiration201181430231020501982
  • BlackstockFCWebsterKEMcDonaldCFHillCJComparable improvements achieved in chronic obstructive pulmonary disease through pulmonary rehabilitation with and without a structured educational intervention: a randomized controlled trialRespirology201419219320224261584
  • GibsonPGPowellHWilsonASelf-management education and regular practitioner review for adults with asthmaCochrane Database of Systematic Reviews20023CD001117
  • TrappenburgJCMonninkhofEMBourbeauJEffect of an action plan with ongoing support by a case manager on exacerbation-related outcome in patients with COPD: a multicentre randomised controlled trialThorax2011661197798421785156
  • BischoffEWHamdDHSedenoMEffects of written action plan adherence on COPD exacerbation recoveryThorax2011661263121037270
  • BourbeauJJulienMMaltaisFChronic Obstructive Pulmonary Disease axis of the Respiratory Network Fonds de la Recherche en Santé du QuébecReduction of hospital utilization in patients with chronic obstructive pulmonary disease: a disease-specific self-management interventionArch Intern Med2003163558559112622605
  • FanVSGazianoJMLewRA comprehensive care management program to prevent chronic obstructive pulmonary disease hospitalizations: a randomized, controlled trialAnn Intern Med20121561067368322586006
  • Chronic obstructive pulmonary disease: management of chronic obstructive pulmonary disease in adults in primary and secondary care (partial update) [webpage on the Internet]BethesdaNational Institute for Health and Care Excellence Available from: http://publications.nice.org.uk/chronic-obstructive-pulmonary-disease-cg101Accessed March 20, 2014
  • MooreRPBerlowitzDJDenehyLA randomised trial of domiciliary, ambulatory oxygen in patients with COPD and dyspnoea but without resting hypoxaemiaThorax2011661323720880870
  • NonoyamaMLBrooksDGuyattGHGoldsteinRSEffect of oxygen on health quality of life in patients with chronic obstructive pulmonary disease with transient exertional hypoxemiaAm J Respir Crit Care Med2007176434334917446339
  • McKeonJLMurree-AllenKSaundersNASupplemental oxygen and quality of sleep in patients with chronic obstructive lung diseaseThorax19894431841882650011
  • ChaouatAWeitzenblumEKesslerRA randomized trial of nocturnal oxygen therapy in chronic obstructive pulmonary disease patientsEur Respir J19991451002100810596681
  • FletcherECLuckettRAGoodnight-WhiteSMillerCCQianWCostarangos-GalarzaCA double-blind trial of nocturnal supplemental oxygen for sleep desaturation in patients with chronic obstructive pulmonary disease and a daytime PaO2 above 60 mmHgAm Rev Respir Dis19921455107010761586049
  • DeanMMEnd-of-life care for COPD patientsPrim Care Respir J2008171465018264648
  • JenningsALDaviesANHigginsJPGibbsJSBroadleyKEA systematic review of the use of opioids in the management of dyspnoeaThorax2002571193994412403875
  • McDonaldVMHigginsIGibsonPGInsight into older peoples’ healthcare experiences with managing COPD, asthma, and asthma-COPD overlapJ Asthma201350549750423638867
  • JonesIKirbyAOrmistonPThe needs of patients dying of chronic obstructive pulmonary disease in the communityFam Pract200421331031315128695
  • TraversJMarshSCaldwellBExternal validity of randomized controlled trials in COPDRespir Med200710161313132017113277
  • WenzelSEAsthma: defining of the persistent adult phenotypesLancet2006368953780481316935691
  • LangePPersistent airway obstruction in asthmaAm J Respir Crit Care Med201318711223281346
  • BeasleyRWeatherallMTraversJShirtcliffePTime to define the disorders of the syndrome of COPDLancet2009374969167067219716947
  • NelsonHSWeissSTBleeckerERYanceySWDorinskyPMSMART Study GroupThe Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterolChest20061291152616424409