References
- MathersCDLoncarDProjections of global mortality and burden of disease from 2002 to 2030PLoS Med2006311e44217132052
- FullertonDGBruceNGordonSBIndoor air pollution from biomass fuel smoke is a major health concern in the developing worldTrans R Soc Trop Med Hyg2008102984385118639310
- HoggJCMcDonoughJESuzukiMSmall airway obstruction in COPD: new insights based on micro-CT imaging and MRI imagingChest201314351436144323648907
- DunnillMSRyderRA quantitative study of the relationship between chronic bronchitis, emphysema and smokingChest197159suppl35S+5575683
- SohalSSReidDSoltaniAReticular basement membrane fragmentation and potential epithelial mesenchymal transition is exaggerated in the airways of smokers with chronic obstructive pulmonary diseaseRespirology201015693093820630030
- SohalSSReidDSoltaniAEvaluation of epithelial mesenchymal transition in patients with chronic obstructive pulmonaryRespir Res20111213021970519
- SoltaniAMullerHKSohalSSDistinctive characteristics of bronchial reticular basement membrane and vessel remodelling in chronic obstructive pulmonary disease (COPD) and in asthma: they are not the same diseaseHistopathology201260696497022320998
- SohalSSWaltersEHEpithelial mesenchymal transition (EMT) in small airways of COPD patientsThorax201368878378423492370
- MilaraJPeiroTSerranoACortijoJEpithelial to mesenchymal transition is increased in patients with COPD and induced by cigarette smokeThorax201368541042023299965
- WaltersEHReidDSoltaniAWardCAngiogenesis: a potentially critical part of remodelling in chronic airway diseases?Pharmacol Ther2008118112813718358536
- HiroshimaKIyodaAShibuyaKEvidence of neoangiogenesis and an increase in the number of proliferating cells within the bronchial epithelium of smokersCancer20029571539154512237923
- ZeisbergEMPotentaSESugimotoHZeisbergMKalluriRFibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transitionJ Am Soc Nephrol200819122282228718987304
- KalluriRWeinbergRAThe basics of epithelial-mesenchymal transitionJ Clin Invest200911961420142819487818
- ParimonTChienJWBrysonCLMcDonellMBUdrisEMAuDHInhaled corticosteroids and risk of lung cancer among patients with chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2007175771271917185647
- YangIARelanVWrightCMCommon pathogenic mechanisms and pathways in the development of COPD and lung cancerExpert Opin Ther Targets201115443945621284573
- HanahanDWeinbergRAHallmarks of cancer: the next generationCell2011144564667421376230
- GOLDGlobal Initiative for Chronic Obstructive Pulmonary Lung Disease2013 Available from: http://www.goldcopd.org
- HoggJCChuFUtokaparchSThe nature of small airway obstruction in chronic obstructive pulmonary diseaseN Engl J Med2004350262645265315215480
- SohalSSSoltaniAReidDA randomized controlled trial of inhaled corticosteroids (ICS) on markers of epithelial-mesenchymal transition (EMT) in large airway samples in COPD: an exploratory proof of concept studyInt J Chron Obstruct Pulmon Dis2014953354224920891
- ShuklaSDSohalSSMahmoodMQReidDMullerHKWaltersEHAirway epithelial platelet-activating factor receptor expression is markedly upregulated in chronic obstructive pulmonary diseaseInt J Chron Obstruct Pulmon Dis2014985386125143722
- YanaiMSekizawaKOhruiTSasakiHTakishimaTSite of airway obstruction in pulmonary disease: direct measurement of intrabronchial pressureJ Appl Physiol (1985)1992723101610231568955
- PrudkinLLiuDDOzburnNCEpithelial-to-mesenchymal transition in the development and progression of adenocarcinoma and squamous cell carcinoma of the lungMod Pathol200922566867819270647
- BurgelPRBourdinAChanezPUpdate on the roles of distal airways in COPDEur Respir Rev20112011972221357888
- ScottonCJChambersRCMolecular targets in pulmonary fibrosis*: the myofibroblast in focusChest200713241311132117934117
- MilaraJSerranoAPeiróTAclidinium inhibits cigarette smoke-induced lung fibroblast-to-myofibroblast transitionEur Respir J20134161264127423018909
- CowardWDeaconKPangLActivation of epidermal growth factor receptor (EGFR) is required for Tgfβ1-induced epithelial-mesenchymal transition (EMT) in idiopathic pulmonary fibrosis (IPF)Am J Respir Crit Care Med2013187A4818
- MilaraJPeiróTSerranoARoflumilast N-oxide inhibits bronchial epithelial to mesenchymal transition induced by cigarette smoke in smokers with COPDPulm Pharmacol Ther201428213814824525294
- WangQWangYZhangYZhangYXiaoWThe role of uPAR in epithelial-mesenchymal transition in small airway epithelium of patients with chronic obstructive pulmonary diseaseRespir Res2013146723806081
- YangKSongYTangYBmAChRs activation induces epithelial-mesenchymal transition on lung epithelial cellsBMC Pulm Med2014145324678619
- KeithRLMillerYEGemmillRMAngiogenic squamous dysplasia in bronchi of individuals at high risk for lung cancerClin Cancer Res2000651616162510815878
- FontaniniGVignatiSBiginiDNeoangiogenesis: a putative marker of malignancy in non-small-cell lung cancer (NSCLC) developmentInt J Cancer19966756156198782647
- SarrazinSMaurageCDelmasDLassallePDeleheddeMEndocan as a biomarker of endothelial dysfunction in cancerJ Cancer Sci Ther2010264752
- IwatsukiMMimoriKYokoboriTEpithelial-mesenchymal transition in cancer development and its clinical significanceCancer Sci2010101229329919961486
- PainMBermudezOLacostePTissue remodelling in chronic bronchial diseases: from the epithelial to mesenchymal phenotypeEur Respir Rev20142313111813024591669