Exacerbations of COPD

References

• JonesPWLamarcaRChuecosFCharacterisation and impact of reported and unreported exacerbations: results from ATTAINEur Respir J20144451156116525234803
   PubMed Web of Science ®Google Scholar
• SpencerSJonesPWTime course of recovery of health status following an infective exacerbation of chronic bronchitisThorax200358758959312832673
   PubMed Web of Science ®Google Scholar
• SuissaSDell’AnielloSErnstPLong-term natural history of chronic obstructive pulmonary disease: severe exacerbations and mortalityThorax2012671195796322684094
   PubMed Web of Science ®Google Scholar
• CelliBRThomasNEAndersonJAEffect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: results from the TORCH studyAm J Respir Crit Care Med2008178433233818511702
   PubMed Web of Science ®Google Scholar
• BafadhelMMcKennaSTerrySBlood eosinophils to direct corticosteroid treatment of exacerbations of chronic obstructive pulmonary disease: a randomized placebo-controlled trialAm J Respir Crit Care Med20121861485522447964
   PubMed Web of Science ®Google Scholar
• HanMKAgustiACalverleyPMChronic obstructive pulmonary disease phenotypes: the future of COPDAm J Respir Crit Care Med2010182559860420522794
   PubMed Web of Science ®Google Scholar
• VestboJHurdSSAgustíAGGlobal strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD Executive SummaryAm J Respir Crit Care Med2013187434736522878278
   PubMed Web of Science ®Google Scholar
• Rodriguez-RoisinRToward a consensus definition for COPD exacerbationsChest20001175 Suppl 2398S401S10843984
   PubMed Web of Science ®Google Scholar
• BurgeSWedzichaJACOPD exacerbations: definitions and classificationsEur Respir J20032141 Suppl46s53s
   Web of Science ®Google Scholar
• SethiSMurphyTFInfection in the pathogenesis and course of chronic obstructive pulmonary diseaseN Engl J Med2008359222355236519038881
   PubMed Web of Science ®Google Scholar
• BafadhelMMcKennaSTerrySAcute exacerbations of chronic obstructive pulmonary disease: identification of biologic clusters and their biomarkersAm J Respir Crit Care Med2011184666267121680942
   PubMed Web of Science ®Google Scholar
• BrightlingCEMonteiroWWardRSputum eosinophilia and short-term response to prednisolone in chronic obstructive pulmonary disease: a randomised controlled trialLancet200035692401480148511081531
   PubMed Web of Science ®Google Scholar
• HurstJRVestboJAnzuetoASusceptibility to exacerbation in chronic obstructive pulmonary diseaseN Engl J Med2010363121128113820843247
   PubMed Web of Science ®Google Scholar
• WedzichaJABrillSEAllinsonJPDonaldsonGCMechanisms and impact of the frequent exacerbator phenotype in chronic obstructive pulmonary diseaseBMC Med20131118123945277
   PubMed Web of Science ®Google Scholar
• BhowmikASeemungalTASapsfordRJWedzichaJARelation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbationsThorax200055211412010639527
   PubMed Web of Science ®Google Scholar
• GroenewegenKHPostmaDSHopWCWieldersPLSchlosserNJWoutersEFIncreased systemic inflammation is a risk factor for COPD exacerbationsChest2008133235035718198263
   PubMed Web of Science ®Google Scholar
• JonesPWChenWHWilcoxTKSethiSLeidyNKCharacterizing and quantifying the symptomatic features of COPD exacerbationsChest201113961388139421071529
   PubMed Web of Science ®Google Scholar
• MackayAJDonaldsonGCPatelARSinghRKowlessarBWedzichaJADetection and severity grading of COPD exacerbations using the exacerbations of Chronic Obstructive Pulmonary Disease Tool (EXACT)Eur Respir J201443373574423988767
   PubMed Web of Science ®Google Scholar
• CoteCGDordellyLJCelliBRImpact of COPD exacerbations on patient-centered outcomesChest2007131369670417356082
   PubMed Web of Science ®Google Scholar
• DonaldsonGCWilkinsonTMHurstJRPereraWRWedzichaJAExacerbations and time spent outdoors in chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2005171544645215579723
   PubMed Web of Science ®Google Scholar
• SeemungalTADonaldsonGCPaulEABestallJCJeffriesDJWedzichaJAEffect of exacerbation on quality of life in patients with chronic obstructive pulmonary diseaseAm J Respir Crit Care Med19981575 Pt 1141814229603117
   PubMed Web of Science ®Google Scholar
• National Institute for Health and Care Excellence [homepage on the Internet]NICE Clinical Guideline 101, Management of chronic obstructive pulmonary disease in adults in primary and secondary care (partial update) [updated 2010] Available from: http://www.nice.org.uk/guidance/CG101Accessed October 21, 2015
   Google Scholar
• DaviesLAngusRMCalverleyPMOral corticosteroids in patients admitted to hospital with exacerbations of chronic obstructive pulmonary disease: a prospective randomised controlled trialLancet1999354917745646010465169
   PubMed Web of Science ®Google Scholar
• NiewoehnerDEErblandMLDeupreeRHEffect of systemic glucocorticoids on exacerbations of chronic obstructive pulmonary disease. Department of Veterans Affairs Cooperative Study GroupN Engl J Med1999340251941194710379017
   PubMed Web of Science ®Google Scholar
• AbrougFKrishnanJAWhat is the right dose of systemic corticosteroids for intensive care unit patients with chronic obstructive pulmonary disease exacerbations? A question in search of a definitive answerAm J Respir Crit Care Med201418991014101624787061
   PubMed Web of Science ®Google Scholar
• Global Initiative for Chronic Obstructive Lung Disease [homepage on the Internet]Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease [updated 2015] Available from: http://www.goldcopd.org/uploads/users/files/GOLD_Report_2015_Feb18.pdfAccessed October 21, 2015
   Google Scholar
• WaltersJATanDJWhiteCJGibsonPGWood-BakerRWaltersEHSystemic corticosteroids for acute exacerbations of chronic obstructive pulmonary diseaseCochrane Database Syst Rev20149CD00128825178099
   PubMed Web of Science ®Google Scholar
• LeuppiJDSchuetzPBingisserRShort-term vs conventional glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease: the REDUCE randomized clinical trialJAMA2013309212223223123695200
   PubMed Web of Science ®Google Scholar
• KiserTHAllenRRValuckRJMossMVandivierRWOutcomes associated with corticosteroid dosage in critically ill patients with acute exacerbations of chronic obstructive pulmonary diseaseAm J Respir Crit Care Med201418991052106424617842
   PubMed Web of Science ®Google Scholar
• BafadhelMDaviesLCalverleyPMAaronSDBrightlingCEPavordIDBlood eosinophil guided prednisolone therapy for exacerbations of COPD: a further analysisEur Respir J201444378979124925917
   PubMed Web of Science ®Google Scholar
• DonohueJFHerjeNCraterGRickardKCharacterization of airway inflammation in patients with COPD using fractional exhaled nitric oxide levels: a pilot studyInt J Chron Obstruct Pulmon Dis2014974575125053884
   PubMed Web of Science ®Google Scholar
• DummerJFEptonMJCowanJOPredicting corticosteroid response in chronic obstructive pulmonary disease using exhaled nitric oxideAm J Respir Crit Care Med2009180984685219661244
   PubMed Web of Science ®Google Scholar
• KunisakiKMRiceKLJanoffENRectorTSNiewoehnerDEExhaled nitric oxide, systemic inflammation, and the spirometric response to inhaled fluticasone propionate in severe chronic obstructive pulmonary disease: a prospective studyTher Adv Respir Dis200822556419124359
   PubMedGoogle Scholar
• VollenweiderDJJarrettHSteurer-SteyCAGarcia-AymerichJPuhanMAAntibiotics for exacerbations of chronic obstructive pulmonary diseaseCochrane Database Syst Rev201212CD01025723235687
   PubMedGoogle Scholar
• NouiraSMarghliSBelghithMBesbesLElatrousSAbrougFOnce daily oral ofloxacin in chronic obstructive pulmonary disease exacerbation requiring mechanical ventilation: a randomised placebo-controlled trialLancet200135892982020202511755608
   PubMed Web of Science ®Google Scholar
• DanielsJMSchoorlMSnijdersDProcalcitonin vs C-reactive protein as predictive markers of response to antibiotic therapy in acute exacerbations of COPDChest201013851108111520576731
   PubMed Web of Science ®Google Scholar
• HerathSCPoolePProphylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD)Cochrane Database Syst Rev201311CD00976424288145
   PubMed Web of Science ®Google Scholar
• PlantPKOwenJLElliottMWEarly use of non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease on general respiratory wards: a multicentre randomised controlled trialLancet200035592191931193510859037
   PubMed Web of Science ®Google Scholar
• PlantPKOwenJLParrottSElliottMWCost effectiveness of ward based non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease: economic analysis of randomised controlled trialBMJ2003326739695612727767
   PubMed Web of Science ®Google Scholar
• StruikFMSprootenRTKerstjensHANocturnal non-invasive ventilation in COPD patients with prolonged hypercapnia after ventilatory support for acute respiratory failure: a randomised, controlled, parallel-group studyThorax201469982683424781217
   PubMed Web of Science ®Google Scholar
• BrillSEWedzichaJAOxygen therapy in acute exacerbations of chronic obstructive pulmonary diseaseInt J Chron Obstruct Pulmon Dis201491241125225404854
   PubMed Web of Science ®Google Scholar
• JeppesenEBrurbergKGVistGEHospital at home for acute exacerbations of chronic obstructive pulmonary diseaseCochrane Database Syst Rev20125CD00357322592692
   PubMed Web of Science ®Google Scholar
• RocheNZureikMSoussanDNeukirchFPerrotinDPredictors of outcomes in COPD exacerbation cases presenting to the emergency departmentEur Respir J200832495396118508819
   PubMed Web of Science ®Google Scholar
• RocheNChavaillonJMMaurerCZureikMPiquetJA clinical in-hospital prognostic score for acute exacerbations of COPDRespir Res2014159925158759
   PubMed Web of Science ®Google Scholar
• HurstJRDonaldsonGCQuintJKGoldringJJBaghai-RavaryRWedzichaJATemporal clustering of exacerbations in chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2009179536937419074596
   PubMed Web of Science ®Google Scholar
• DonaldsonGCWedzichaJACOPD exacerbations. 1: EpidemiologyThorax200661216416816443707
   PubMed Web of Science ®Google Scholar
• BurgePSCalverleyPMJonesPWSpencerSAndersonJAMaslenTKRandomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: the ISOLDE trialBMJ200032072451297130310807619
   PubMed Web of Science ®Google Scholar
• CalverleyPMAndersonJACelliBSalmeterol and fluticasone propionate and survival in chronic obstructive pulmonary diseaseN Engl J Med2007356877578917314337
   PubMed Web of Science ®Google Scholar
• DransfieldMTBourbeauJJonesPWOnce-daily inhaled fluticasone furoate and vilanterol versus vilanterol only for prevention of exacerbations of COPD: two replicate double-blind, parallel-group, randomised controlled trialsLancet Respir Med20131321022324429127
   PubMed Web of Science ®Google Scholar
• SuissaSPatenaudeVLapiFErnstPInhaled corticosteroids in COPD and the risk of serious pneumoniaThorax201368111029103624130228
   PubMed Web of Science ®Google Scholar
• PascoeSLocantoreNDransfieldMTBarnesNCPavordIDBlood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease: a secondary analysis of data from two parallel randomised controlled trialsLancet Respir Med20153643544225878028
   PubMed Web of Science ®Google Scholar
• SiddiquiSHGuasconiAVestboJBlood eosinophils: a bio-marker of response to extrafine beclomethasone/formoterol in chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2015192452352526051430
   PubMed Web of Science ®Google Scholar
• GonemSRajVWardlawAJPavordIDGreenRSiddiquiSPhenotyping airways disease: an A to E approachClin Exp Allergy201242121664168323181785
   PubMed Web of Science ®Google Scholar
• VogelmeierCHedererBGlaabTTiotropium versus salmeterol for the prevention of exacerbations of COPDN Engl J Med2011364121093110321428765
   PubMed Web of Science ®Google Scholar
• RabeKFFabbriLMIsraelEEffect of ADRB2 polymorphisms on the efficacy of salmeterol and tiotropium in preventing COPD exacerbations: a prespecified substudy of the POET-COPD trialLancet Respir Med201421445324461901
   PubMed Web of Science ®Google Scholar
• WedzichaJADecramerMFickerJHAnalysis of chronic obstructive pulmonary disease exacerbations with the dual bronchodilator QVA149 compared with glycopyrronium and tiotropium (SPARK): a randomised, double-blind, parallel-group studyLancet Respir Med20131319920924429126
   PubMed Web of Science ®Google Scholar
• MagnussenHDisseBRodriguez-RoisinRWithdrawal of inhaled glucocorticoids and exacerbations of COPDN Engl J Med2014371141285129425196117
   PubMed Web of Science ®Google Scholar
• AlbertRKConnettJBaileyWCAzithromycin for prevention of exacerbations of COPDN Engl J Med2011365868969821864166
   PubMed Web of Science ®Google Scholar
• HanMKTayobNMurraySPredictors of chronic obstructive pulmonary disease exacerbation reduction in response to daily azithromycin therapyAm J Respir Crit Care Med2014189121503150824779680
   PubMed Web of Science ®Google Scholar
• CalverleyPMRabeKFGoehringUMKristiansenSFabbriLMMartinezFJRoflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trialsLancet2009374969168569419716960
   PubMed Web of Science ®Google Scholar
• ZhengJPKangJHuangSGEffect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (PEACE Study): a randomised placebo-controlled studyLancet200837196292013201818555912
   PubMed Web of Science ®Google Scholar
• ZhengJPWenFQBaiCXTwice daily N-acetylcysteine 600 mg for exacerbations of chronic obstructive pulmonary disease (PANTHEON): a randomised, double-blind placebo-controlled trialLancet Respir Med20142318719424621680
   PubMed Web of Science ®Google Scholar
• PoolePJChackoEWood-BakerRWCatesCJInfluenza vaccine for patients with chronic obstructive pulmonary diseaseCochrane Database Syst Rev20004CD00273311034751
   PubMedGoogle Scholar
• WaltersJASmithSPoolePGrangerRHWood-BakerRInjectable vaccines for preventing pneumococcal infection in patients with chronic obstructive pulmonary diseaseCochrane Database Syst Rev201011CD00139021069668
   PubMed Web of Science ®Google Scholar
• SinDDManSFWhy are patients with chronic obstructive pulmonary disease at increased risk of cardiovascular diseases? The potential role of systemic inflammation in chronic obstructive pulmonary diseaseCirculation2003107111514151912654609
   PubMed Web of Science ®Google Scholar
• van GestelYRHoeksSESinDDEffect of statin therapy on mortality in patients with peripheral arterial disease and comparison of those with versus without associated chronic obstructive pulmonary diseaseAm J Cardiol2008102219219618602520
   PubMed Web of Science ®Google Scholar
• YoungRPHopkinsRJUpdate on the potential role of statins in chronic obstructive pulmonary disease and its co-morbiditiesExpert Rev Respir Med20137553354424138695
   PubMed Web of Science ®Google Scholar
• CrinerGJConnettJEAaronSDSimvastatin for the prevention of exacerbations in moderate-to-severe COPDN Engl J Med2014370232201221024836125
   PubMed Web of Science ®Google Scholar
• MortensenEMCopelandLAPughMJImpact of statins and ACE inhibitors on mortality after COPD exacerbationsRespir Res2009104519493329
   PubMed Web of Science ®Google Scholar
• QuintJKHerrettEBhaskaranKEffect of beta blockers on mortality after myocardial infarction in adults with COPD: population based cohort study of UK electronic healthcare recordsBMJ2013347f665024270505
   PubMed Web of Science ®Google Scholar
• WhiteWBCookeGEKoweyPRCardiovascular safety in patients receiving roflumilast for the treatment of COPDChest2013144375876523412642
   PubMed Web of Science ®Google Scholar