References
- AngiolilloDJFernandez-OrtizABernardoEVariability in individual responsiveness to clopidogrel: clinical implications, management, and future perspectivesJ Am Coll Cardiol200749141505151617418288
- GurbelPABlidenKPGuyerKPlatelet reactivity in patients and recurrent events post-stenting: results of the PREPARE POST-STENTING studyJ Am Coll Cardiol200546101820182616286165
- BuonamiciPMarcucciRMiglioriniAImpact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosisJ Am Coll Cardiol200749242312231717572245
- BreetNJvan WerkumJWBoumanHJComparison of platelet function tests in predicting clinical outcome in patients undergoing coronary stent implantationJAMA2010303875476220179285
- TrenkDHochholzerWFrommMFCytochrome P450 2C19 681G>A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug-eluting or bare-metal stentsJ Am Coll Cardiol200851201925193418482659
- MegaJLCloseSLWiviottSDCytochrome P-450 polymorphisms and response to clopidogrelN Engl J Med2009360435436219106084
- ColletJPHulotJSPenaACytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort studyLancet2009373966030931719108880
- SimonTVerstuyftCMary-KrauseMGenetic determinants of response to clopidogrel and cardiovascular eventsN Engl J Med2009360436337519106083
- MegaJLSimonTColletJPReduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysisJAMA2010304161821183020978260
- BoumanHJSchömigEvan WerkumJWParaoxonase-1 is a major determinant of clopidogrel efficacyNat Med201117111011621170047
- ShuldinerARO’ConnellJRBlidenKPAssociation of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapyJAMA2009302884985719706858
- KreutzRPTantryUSBlidenKPGurbelPAInflammatory changes during the ‘common cold’ are associated with platelet activation and increased reactivity of platelets to agonistsBlood Coagul Fibrinolysis200718871371817982310
- KreutzRPAllooshMMansourKMorbid obesity and metabolic syndrome in Ossabaw miniature swine are associated with increased platelet reactivityDiabetes Metab Syndr Obes201149910521660293
- JakubowskiJAPayneCDLiYGThe use of the VerifyNow P2Y12 point-of-care device to monitor platelet function across a range of P2Y12 inhibition levels following prasugrel and clopidogrel administrationThromb Haemost200899240941518278193
- International HapMap Project [database] Available from: http://www.hapmap.orgAccessed September 26, 2011
- SibbingDKochWMassbergSNo association of paraoxonase- 1 Q192R genotypes with platelet response to clopidogrel and risk of stent thrombosis after coronary stentingEur Heart J201132131605161321527445
- LewisJPFischASRyanKParaoxonase 1 (PON1) gene variants are not associated with clopidogrel responseClin Pharmacol Ther201190456857421881565
- RidegOKomócsiAMagyarlakiTImpact of genetic variants on post-clopidogrel platelet reactivity in patients after elective percutaneous coronary interventionPharmacogenomics20111291269128021806387
- FontanaPJamesRBarazerIRelationship between paraoxonase- 1 activity, its Q192R genetic variant and clopidogrel responsiveness in the ADRIE studyJ Thromb Haemost2011981664166621692977
- TrenkDHochholzerWFrommMFParaoxonase-1 Q192R polymorphism and antiplatelet effects of clopidogrel in patients undergoing elective coronary stent placementCirc Cardiovasc Genet20114442943621685174
- SimonTStegPGBecquemontLEffect of paraoxonase-1 polymorphism on clinical outcomes in patients treated with clopidogrel after an acute myocardial infarctionClin Pharmacol Ther201190456156721918510
- GeislerTSchaeffelerEDipponJCYP2C19 and nongenetic factors predict poor responsiveness to clopidogrel loading dose after coronary stent implantationPharmacogenomics2008991251125918781853
- UmemuraKFurutaTKondoKThe common gene variants of CYP2C19 affect pharmacokinetics and pharmacodynamics in an active metabolite of clopidogrel in healthy subjectsJ Thromb Haemost2008681439144118532997