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Review

Wound pruritus: pathophysiology and management

Pages 119-127 | Published online: 12 Aug 2015

References

  • Upton D, Richardson C, Andrews A, Rippon M. Wound pruritus: prevalence, aetiology and treatment. J Wound Care. 2013;22(9):501–508.
  • Paus R, Schmelz M, Biro T, Steinhoff M. Frontiers in pruritus research: scratching the brain for more effective itch therapy. J Clin Invest. 2006;16(5):1174–1185.
  • Garibyan L, Rheingold CG, Lerner EA. Understanding the pathophysiology of itch. Dermatol Ther. 2013;26(2):86–91.
  • Tawa MC. 7th World Congress on Itch. J Dermatol Nurses’ Assoc. 2014;6(2):82–83.
  • Paul J. Characteristics of chronic wounds that itch. Adv Skin Wound Care. 2013;26(7):320–332.
  • Guarneri C, Terranova M, Terranova G, Guarneri F. The future: critical knowledge about anti-itch therapy. Dermatol Ther. 2005;18:363–365.
  • Ikoma A, Steinhoff M, Stander S, Yosipovitch G, Schmelz M. The neurobiology of itch. Nat Rev Neurosci. 2006;7:535–547.
  • Greaves MW, Khalifa N. Itch: more than skin deep. Inter Arch Allergy Immunol. 2004;135(2):166–172.
  • Hawkins JM, Allen R, editors. The Oxford Encyclopedic English Dictionary. Oxford, UK: Clarindon Press; 1991.
  • Stedman TL. Stedman’s Medical Dictionary. 28th ed. Philadelphia, PA: Lippincott, Williams & Wilkins; 2006.
  • Waxler B, Dadabhoy ZP, Stojiljkovic L, Rabito SF. Primer of postoperative pruritus for anesthesiologists. Anesthesiology. 2005;103:168–178.
  • Bernhard JD, editor. Itch: Mechanisms and Management of Pruritus. New York, NY: McGraw-Hill, Inc.; 1994.
  • Paul J. A cross-sectional study of chronic wound-related pain and itching. Ostomy Wound Manage. 2013;59(7):28–34.
  • VanLoey NE, Bremmer M, Faber AW, et al. Itching following burns: epidemiology and predictors. Br J Dermatol. 2008;158(1):95–100.
  • Lazarus G S, Cooper DM, Knighton DR, et al. Definitions and guidelines for assessment of wounds and evaluation of healing. Arch Dermatol. 1994;130:489–493.
  • Doughty DB, Sparks-Defries B. Wound-healing physiology. In: Bryant RA, Nix DP, editors. Acute and Chronic Wounds: Current Management Concepts. St Louis, MO: Mosby/Elsevier; 2007:307–336.
  • Yosipovitch G, Greaves MW. Definitions of itch. In: Yosipovitch G, Greaves MW, Fleischer AB, Jr, McGlone F, editors. Itch: Basic Mechanisms and Therapy. New York, NY: Marcel Dekker, Inc.; 2004:1–4.
  • Stander S, Weisshaar E, Mettang T, et al. Clinical classification of itch: a position paper of the International Forum for the Study of Itch. Acta Derm Venereol. 2007;87:291–294.
  • Twycross R, Greaves MW, Handwerker H, et al. Itch: scratching more than the surface. QJM. 2003;96(1):7–26.
  • Patel TS, Dong X. An itch to be scratched. Neuron. 2010;68(4):334–339.
  • Han L, Ma C, Liu Q, et al. A subpopulation of nociceptors specifically linked to itch. Nat Neurosci. 2013;16(2):174–182.
  • Schmelz M, Schmidt R, Bickel A, Handwerker HO, Torebjork HE. Specific C-receptors for itch in human skin. J Neurosci. 1997;17(20):8003–8008.
  • Stander S, Schmelz M. Chronic itch and pain – similarities and differences. Eur J Pain. 2006;10(5):473–478.
  • Heymann WR. Itch. J Am Acad Dermatol. 2006;54(4):705–706.
  • Stander S, Steinhoff M, Schmelz M, Weisshaar E, Metze D, Luger T. Neurophysiology of pruritus: cutaneous elicitation of itch. Arch Dermatol. 2003;139:1463–1470.
  • Baker RA, Zeller RA, Klein RL, et al. Burn wound itch control using H1 and H2 antagonists. J Burn Care Rehabil. 2001;22(4):263–268.
  • Sun Y, Chen Z. A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord. Nature. 2007;448(7154):700–703.
  • Swain MG. Gastrin-releasing peptide and pruritus: more than just scratching the surface. J Hepatol. 2008;48:681–683.
  • Metze D. Skin nerve anatomy: neuropeptide distribution and its relationship to itch. In: Yosipovitch G, Greaves MW, Fleischer AB Jr, McGlone F, editors, Itch: Basic Mechanisms and Therapy. New York, NY: Marcel Dekker, Inc.; 2004:305–314.
  • Yosipovitch G, Papoiu AD. What causes itch in atopic dermatitis? Curr Allergy Asthma Rep. 2008;8:306–311.
  • Johanek LM, Meyer RA, Hartke T, et al. Psychophysical physiological evidence for parallel afferent pathways mediating the sensation of itch. J Neurosci. 2007;27(28):4790–4797.
  • Andrew D, Craig AD. Spinothalamic lamina I neurons selectively sensitive to histamine: a central neural pathway for itch. Nat Neurosci. 2001;4(1):72–77.
  • Darsow U, Drzezga A, Ring J. Central nervous system imaging of itch with PET. In: Yosipovitch G, Greaves MW, Fleischer AB, Jr, McGlone F, editors. Itch: Basic Mechanisms and Therapy. New York, NY: Marcel Dekker, Inc.; 2004:63–70.
  • Yosipovitch G, Greaves M, Schmelz M. Itch. Lancet. 2003;362:690–694.
  • Drzezga A, Darsow U, Treede R, et al. Central activation by histamine-induced itch: analogies to pain processing: a correlational analysis of O-15 H2O positron emission tomography studies. Pain. 2001;92:295–305.
  • Yosipovitch G, Ishiuji Y, Patel TS, et al. The brain processing of scratching. J Invest Dermatol. 2008;128:1806–1811.
  • Davidson S, Zhang X, Khasabov SG, Simone DA, Giesler GJ Jr. Relief of scratching: State-dependent inhibition of primate spinothalamic tract neurons. Nat Neurosci. 2009;12(5):544–546.
  • Yosipovitch G, Duque MI, Fast K, Dawn AG, Coghill RC. Scratching and noxious heat stimuli inhibit itch in humans: a psychophysical approach. Br J Dermatol. 2007;156:629–634.
  • Yosipovitch G, Hundley JL. Practical guide lines for the relief of itch. Dermatol Nurs. 2004;16(4):325–328.
  • Leknes SG, Bantick S, Willis CM, Wilkinson JP, Wise RG, Tracey I. Itch and motivation to scratch: an investigation of the central and peripheral correlates of allergen- and histamine-induced itch in humans. J Neurophysiol. 2007;97:415–422.
  • Schmelz M, Handwerker HO. Neurophysiologic basis of itch. In: Yosipovitch G, Greaves MW, Fleischer AB, Jr, McGlone F, editors. Itch: Basic Mechanisms and Therapy. New York, NY: Marcel Dekker, Inc.; 2004:5–12.
  • Pogatzki-Zahn E, Marziniak M, Schneider G, Luger TA, Stander S. Chronic pruritus: targets, mechanisms and future therapies. Drug News Perspect. 2008;21(10):541–551.
  • Schmelz M. Modulators of pruritus: peripheral and central sensitization. In: Misery L, Stander S, editors. Pruritus. London, UK: Springer-Verlag; 2010:22–29.
  • Gieler U, Niemeier V, Brosig B, Kupfer J. Psychosomatic aspects of pruritus. Psychosom Dermatol. 2002;3:6–13.
  • Yelverton CB, Yosipovitch G. Exogenous factors in the itch response. Curr Probl Dermatol. 2007;35:146–153.
  • McMahon SB, Koltzenburg M. Itching for an explanation. Trends Neurosci. 1992;15(12):497–501.
  • Yosipovitch G, Bernhard, JD. Chronic pruritus. N Engl J Med. 2013;368:1625–1634.
  • Farahani PV, Hekmatpou D, Khani SS. Effectiveness of muscle relaxation on pain, pruritus and vital signs of patients with burns. Iran J Crit Care Nurs. 2013;6(2):87–94.
  • Matheson J, Clayton J, Muller M. The reduction of itch during burn wound healing. J Burn Care Rehabil. 2001;22(1):76–81.
  • Mendham, JE. Gabapentin for the treatment of itching produced by burns and wound healing in children: a pilot study. Burns. 2004;30:851–853.
  • Gross S, Overbaugh R, Jansen R. Ondansetron for treating itch in healing burns. Internet J Pain Symptom Contr Palliat Care. 2006;5(1):4.
  • Elmariah SB, Lerner EA. Topical therapies for pruritus. Semin Cutan Med Surg. 2011;30(2):118–126.
  • Biró T, Ko MC, Bromm B, et al. How to fight that nasty itch – from new insights into the neuroimmunological, neuroendocrine, and neurophysiological bases of pruritus to novel therapeutic approaches. Exp Dermatol. 2005;14:225–240.
  • Weisshaar E, Kucenic M, Fleischer AB. Pruritus: a review. Acta Derm Venereol. 2003;213:5–32.
  • Greaves MW. Itch in systemic disease: therapeutic options. Dermatol Ther. 2005;18:323–327.
  • Miller MJS, Reuter BK, Wallace JL, Sharkey KA, Bobrowski P. Mechanistic and clinical assessment of Zangrado, an extract of the Amazonian ethnomedicinesangre de grado, for the treatment of itch. In: Yosipovitch G, Greaves MW, Fleischer AB, Jr, McGlone F, editors. Itch: Basic Mechanisms and Therapy. New York, NY: Marcel Dekker, Inc.; 2004:305–314.
  • Wallengren J. Cutaneous nerve stimulation in the treatment of localized itch. In: Yosipovitch G, Greaves MW, Fleischer AB, Jr, McGlone F, editors. Itch: Basic Mechanisms and Therapy. New York, NY: Marcel Dekker, Inc.; 2004:335–341.
  • Upton D, Penn F, Richardson C, Rippon M. Psychological management of wound pruritus. J Wound Care. 2014;23(6):291–299.
  • Roh YS, Cho H, Oh JO, Yoon CJ. Effects of skin rehabilitation massage therapy on pruritus, skin status and depression in burn survivors. J Korean Acad Nurs. 2007;37(2):221–226.
  • Gurol AP, Polat S, Akcay MN. Itching, pain, and anxiety level are reduced with massage therapy in burned adolescents. J Burn Care Res. 2010;31:429–432.
  • Van Os-medendorp H, Eland-de Kok PC, Ros, WJ, Bruijnzeel- Koomen CA, Grypdonck M. The nursing programme ‘Coping with Itch’: a promising intervention for patients with chronic pruritic skin diseases. J Clin Nurs. 2007;16:1238–1246.
  • Raap U, Stander S, Metz M. Pathophysiology of itch and new treatments. Curr Opin Allergy Clin Immunol. 2011;11:420–427.
  • Sarvis C. Providing relief to patients with malignant burns. Nurs Spectr. 2005;14(23):19–21.