Bibliometric Analysis of Global Trends in Remimazolam-Related Research Over the Past 15 Years: Compared with Propofol

References

• Kilpatrick GJ, McIntyre MS, Cox RF, et al. CNS 7056: a Novel Ultra–short-acting benzodiazepine. Anesthesiology. 2007;107(1):60–66. doi:10.1097/01.anes.0000267503.85085.c0
   PubMed Web of Science ®Google Scholar
• Keam SJ. Remimazolam: first Approval. Drugs. 2020;80(6):625–633. doi:10.1007/s40265-020-01299-8
   PubMed Web of Science ®Google Scholar
• Chen Y, Jin Q, Fang H, et al. Analytic network process: academic insights and perspectives analysis. J Clean Prod. 2019;235:1276–1294. doi:10.1016/j.jclepro.2019.07.016
   Web of Science ®Google Scholar
• Ninkov A, Frank JR, Maggio LA. Bibliometrics: methods for studying academic publishing. Perspect Med Educ. 2022;11(3):173–176. doi:10.1007/s40037-021-00695-4
   PubMed Web of Science ®Google Scholar
• Synnestvedt MB, Chen C, Holmes JH. CiteSpace II: visualization and knowledge discovery in bibliographic databases. AMIA Annu Symp Proc. 2005;2005:724–728.
   PubMedGoogle Scholar
• Aria M, Cuccurullo C. bibliometrix: an R-tool for comprehensive science mapping analysis. J Informetr. 2017;11(4):959–975. doi:10.1016/j.joi.2017.08.007
   Web of Science ®Google Scholar
• van Eck NJ, Waltman L. Software survey: vOSviewer, a computer program for bibliometric mapping. Scientometrics. 2010;84(2):523–538. doi:10.1007/s11192-009-0146-3
   PubMed Web of Science ®Google Scholar
• Chen C. Predictive effects of structural variation on citation counts. J Am Soc Inf Sci. 2012;63(3):431–449. doi:10.1002/asi.21694
   Web of Science ®Google Scholar
• Jones T, Huggett S, Kamalski J. Finding a way through the scientific literature: indexes and measures. World Neurosurg. 2011;76(1):36–38. doi:10.1016/j.wneu.2011.01.015
   PubMed Web of Science ®Google Scholar
• Upton RN, Somogyi AA, Martinez AM, Colvill J, Grant C. Pharmacokinetics and pharmacodynamics of the short-acting sedative CNS 7056 in sheep. Br J Anaesth. 2010;105(6):798–809. doi:10.1093/bja/aeq260
   PubMed Web of Science ®Google Scholar
• Pambianco DJ, Borkett KM, Riff DS, et al. A phase IIb study comparing the safety and efficacy of remimazolam and midazolam in patients undergoing colonoscopy. Gastrointest Endosc. 2016;83(5):984–992. doi:10.1016/j.gie.2015.08.062
   PubMed Web of Science ®Google Scholar
• Wesolowski AM, Zaccagnino MP, Malapero RJ, Kaye AD, Urman RD. Remimazolam: pharmacologic considerations and clinical role in anesthesiology. Pharmacotherapy. 2016;36(9):1021–1027. doi:10.1002/phar.1806
   PubMed Web of Science ®Google Scholar
• Antonik LJ, Goldwater DR, Kilpatrick GJ, Tilbrook GS, Borkett KM. A placebo- and midazolam-controlled phase I single ascending-dose study evaluating the safety, pharmacokinetics, and pharmacodynamics of remimazolam (CNS 7056): part I. Safety, efficacy, and basic pharmacokinetics. Anesth Analg. 2012;115(2):274–283. doi:10.1213/ANE.0b013e31823f0c28
   PubMed Web of Science ®Google Scholar
• Rex DK, Bhandari R, Desta T, et al. A Phase III study evaluating the efficacy and safety of remimazolam (CNS 7056) compared with placebo and midazolam in patients undergoing colonoscopy. Gastrointest Endosc. 2018;88(3):427–437.e6. doi:10.1016/j.gie.2018.04.2351
   PubMed Web of Science ®Google Scholar
• Rex DK, Bhandari R, Lorch DG, Meyers M, Schippers F, Bernstein D. Safety and efficacy of remimazolam in high risk colonoscopy: a randomized trial. Dig Liver Dis. 2021;53(1):94–101. doi:10.1016/j.dld.2020.10.039
   PubMedGoogle Scholar
• Pastis NJ, Yarmus LB, Schippers F, et al. Safety and efficacy of remimazolam compared with placebo and midazolam for moderate sedation during bronchoscopy. Chest. 2019;155(1):137–146. doi:10.1016/j.chest.2018.09.015
   PubMed Web of Science ®Google Scholar
• Dou D, Feng Y, Jiang L. Efficiency and safety of remimazolam and midazolam in digestive endoscopic sedation: systematic review and meta-analysis. Dig Endosc. 2022;34(3):653. doi:10.1111/den.14219
   PubMed Web of Science ®Google Scholar
• Wang M, Zhao X, Yin P, Bao X, Tang H, Kang X. Profile of remimazolam in anesthesiology: a narrative review of clinical research progress. Drug Des Devel Ther. 2022;16:3431–3444. doi:10.2147/DDDT.S375957
   PubMed Web of Science ®Google Scholar
• Chen S, Wang J, Xu X, et al. The efficacy and safety of remimazolam tosylate versus propofol in patients undergoing colonoscopy: a multicentered, randomized, positive-controlled, phase III clinical trial. Am J Transl Res. 2020;12(8):4594–4603.
   PubMed Web of Science ®Google Scholar
• Kilpatrick GJ. Remimazolam: non-clinical and clinical profile of a new sedative/anesthetic agent. Front Pharmacol. 2021;12:690875. doi:10.3389/fphar.2021.690875
   PubMed Web of Science ®Google Scholar
• Park I, Cho M, Nam SW, Hwang JW, Do SH, Na HS. Total intravenous anesthesia induced and maintained by a combination of remimazolam and remifentanil without a neuromuscular blocking agent: a prospective, observational pilot study. BMC Anesthesiol. 2022;22(1):237. doi:10.1186/s12871-022-01779-2
   PubMed Web of Science ®Google Scholar
• Doi M, Hirata N, Suzuki T, Morisaki H, Morimatsu H, Sakamoto A. Safety and efficacy of remimazolam in induction and maintenance of general anesthesia in high-risk surgical patients (ASA Class III): results of a multicenter, randomized, double-blind, parallel-group comparative trial. J Anesth. 2020;34(4):491–501. doi:10.1007/s00540-020-02776-w
   PubMed Web of Science ®Google Scholar
• Doi M, Morita K, Takeda J, Sakamoto A, Yamakage M, Suzuki T. Efficacy and safety of remimazolam versus propofol for general anesthesia: a multicenter, single-blind, randomized, parallel-group, phase IIb/III trial. J Anesth. 2020;34(4):543–553. doi:10.1007/s00540-020-02788-6
   PubMed Web of Science ®Google Scholar
• Zhou J, Leonowens C, Ivaturi VD, et al. Population pharmacokinetic/pharmacodynamic modeling for remimazolam in the induction and maintenance of general anesthesia in healthy subjects and in surgical subjects. J Clin Anesth. 2020;66:109899. doi:10.1016/j.jclinane.2020.109899
   PubMed Web of Science ®Google Scholar
• Tang Y, Yang X, Shu H, et al. Remimazolam besylate for sedation of postoperative patients in intensive care units: a Phase I, open label, dose-finding study. Chin Med J. 2022;135(17):2134–2136. doi:10.1097/CM9.0000000000002243
   PubMed Web of Science ®Google Scholar
• Tang Y, Yang X, Yu Y, et al. Remimazolam besylate versus propofol for long-term sedation during invasive mechanical ventilation: a pilot study. Crit Care. 2022;26(1):279. doi:10.1186/s13054-022-04168-w
   PubMed Web of Science ®Google Scholar
• Choi JY, Lee HS, Kim JY, et al. Comparison of remimazolam-based and propofol-based total intravenous anesthesia on postoperative quality of recovery: a randomized non-inferiority trial. J Clin Anesth. 2022;82:110955. doi:10.1016/j.jclinane.2022.110955
   PubMed Web of Science ®Google Scholar
• Suzuki Y, Kawashima S, Makino H, Doi M, Nakajima Y. A comparison of remimazolam and propofol for postoperative nausea and vomiting: a propensity score-matched, observational, single-center cohort study. Korean J Anesthesiol. 2022;76:143–151. doi:10.4097/kja.22441
   PubMed Web of Science ®Google Scholar
• Mao Y, Guo J, Yuan J, Zhao E, Yang J. Quality of recovery after general anesthesia with remimazolam in patients’ undergoing urologic surgery: a randomized controlled trial comparing remimazolam with propofol. DDDT. 2022;16:1199–1209. doi:10.2147/DDDT.S359496
   PubMed Web of Science ®Google Scholar
• Lu C, Ren J, Guo X, Qian J. Effects of remimazolam combined with esketamine anesthesia on circulatory and respiratory function during painless gastroenteroscopy. Contrast Media Mol Imaging. 2022;2022:1079099. doi:10.1155/2022/1079099
   PubMed Web of Science ®Google Scholar
• Yi X, Xu W, Li A. The clinical application of remimazolam benzenesulfonate combined with esketamine intravenous anesthesia in endoscopic retrograde cholangiopancreatography. Biomed Res Int. 2022;2022:5628687. doi:10.1155/2022/5628687
   PubMed Web of Science ®Google Scholar
• Xu C, He L, Ren J, et al. Efficacy and safety of remimazolam besylate combined with alfentanil in painless gastroscopy: a randomized, single-blind, parallel controlled study. Contrast Media Mol Imaging. 2022;2022:7102293. doi:10.1155/2022/7102293
   PubMed Web of Science ®Google Scholar
• Dong SA, Guo Y, Liu SS, et al. A randomized, controlled clinical trial comparing remimazolam to propofol when combined with alfentanil for sedation during ERCP procedures. J Clin Anesth. 2023;86:111077. doi:10.1016/j.jclinane.2023.111077
   PubMed Web of Science ®Google Scholar
• Stöhr T, Colin PJ, Ossig J, et al. Pharmacokinetic properties of remimazolam in subjects with hepatic or renal impairment. Br J Anaesth. 2021;127(3):415–423. doi:10.1016/j.bja.2021.05.027
   PubMed Web of Science ®Google Scholar
• Nakanishi T, Sento Y, Kamimura Y, Tsuji T, Kako E, Sobue K. Remimazolam for induction of anesthesia in elderly patients with severe aortic stenosis: a prospective, observational pilot study. BMC Anesthesiol. 2021;21(1):306. doi:10.1186/s12871-021-01530-3
   PubMed Web of Science ®Google Scholar
• Liu T, Lai T, Chen J, et al. Effect of remimazolam induction on hemodynamics in patients undergoing valve replacement surgery: a randomized, double-blind, controlled trial. Pharmacol Res Perspect. 2021;9(5):e00851. doi:10.1002/prp2.851
   PubMed Web of Science ®Google Scholar
• Miyoshi H, Watanabe T, Kido K, et al. Remimazolam requires less vasopressor support during induction and maintenance of general anesthesia in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement: a retrospective analysis from a single center. Biomed Res Int. 2022;2022:6386606. doi:10.1155/2022/6386606
   PubMed Web of Science ®Google Scholar
• Tan Y, Ouyang W, Tang Y, Fang N, Fang C, Quan C. Effect of remimazolam tosilate on early cognitive function in elderly patients undergoing upper gastrointestinal endoscopy. J Gastroenterol Hepatol. 2022;37(3):576–583. doi:10.1111/jgh.15761
   PubMed Web of Science ®Google Scholar
• Ibrahim AE, Taraday JK, Kharasch ED. Bispectral index monitoring during sedation with sevoflurane, midazolam, and propofol. Anesthesiology. 2001;95(5):1151–1159. doi:10.1097/00000542-200111000-00019
   PubMed Web of Science ®Google Scholar
• Schüttler J, Eisenried A, Lerch M, Fechner J, Jeleazcov C, Ihmsen H. Pharmacokinetics and pharmacodynamics of remimazolam (CNS 7056) after continuous infusion in healthy male volunteers: part I. pharmacokinetics and clinical pharmacodynamics. Anesthesiology. 2020;132(4):636–651. doi:10.1097/ALN.0000000000003103
   PubMed Web of Science ®Google Scholar
• Eisenried A, Schuettler J, Lerch M, Ihmsen H, Jeleazcov C. Pharmacokinetics and pharmacodynamics of remimazolam (CNS 7056) after continuous infusion in healthy male volunteers part II. Pharmacodynamics of electroencephalogram effects. Anesthesiology. 2020;132(4):652–666. doi:10.1097/ALN.0000000000003102
   PubMed Web of Science ®Google Scholar
• Horikoshi Y, Kuratani N, Tateno K, et al. Anesthetic management with remimazolam for a pediatric patient with Duchenne muscular dystrophy. Medicine. 2021;100(49):e28209. doi:10.1097/MD.0000000000028209
   PubMed Web of Science ®Google Scholar
• Petkus H, Willer BL, Tobias JD. Remimazolam in a pediatric patient with a suspected family history of malignant hyperthermia. J Med Cases. 2022;13(8):386–390. doi:10.14740/jmc3977
   PubMedGoogle Scholar
• Yamadori Y, Yamagami Y, Matsumoto Y, et al. General anesthesia with remimazolam for a pediatric patient with MELAS and recurrent epilepsy: a case report. JA Clin Rep. 2022;8(1):75. doi:10.1186/s40981-022-00564-x
   PubMed Web of Science ®Google Scholar
• Yang X, Lin C, Chen S, Huang Y, Cheng Q, Yao Y. Remimazolam for the prevention of emergence delirium in children following tonsillectomy and adenoidectomy under sevoflurane anesthesia: a randomized controlled study. Drug Des Devel Ther. 2022;16:3413–3420. doi:10.2147/DDDT.S381611
   PubMed Web of Science ®Google Scholar